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Ticagrelor Impurity 293
Formula: C26H32F2N6O4S
562.64
RM-T030993
2-(((3aR,4S,6R,6aS)-6-((3-((1R,2R)-2-(3,4-difluorophenyl)cyclopropyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Impurity 294
Formula: C25H30F2N6O6S
580.61
RM-T030994
2-hydroxyethyl 2-(((1S,2S,3S,4R)-4-(7-(((1R,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,3-dihydroxycyclopentyl)oxy)acetate

Ticagrelor Impurity 295
Formula: C14H23ClN4O4S
378.87
RM-T030995
(1R,2R,3S,5S)-3-((5-amino-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 296
Formula: C18H27ClN4O6S
462.95
RM-T030996
(3aR,4S,6S,6aS)-6-((5-amino-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl (2-hydroxyethyl) carbonate

Ticagrelor Impurity 297
CAS:2681352-85-0
Formula: C18H24ClN7O4S2
502.01
RM-T030997
2-((6-chloro-5-(7-(2-hydroxyethoxy)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2-(propylthio)pyrimidin-4-yl)oxy)ethan-1-ol

Ticagrelor Impurity 298
Formula: C14H21N5O5S
371.41
RM-T030998
(1R,2R,3S,5R)-3-(7-hydroxy-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 299
Formula: C26H32F2N6O4S
562.64
RM-T030999
2-(((3aS,4R,6S,6aR)-6-((3-((1R,2R)-2-(3,4-difluorophenyl)cyclopropyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

TICAGRELOR IMPURITY 3
CAS:2197189-31-2
Formula: C17H27ClN4O5S
434.94
RM-T030729
2-(((3aR,4S,6R,6aS)-6-((5-amino-6-chloro-2-(propylsulfinyl)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol

Ticagrelor Impurity 301
Formula: C8H15NO3
173.21
RM-T031001
(3aS,4S,6R,6aR)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol

Ticagrelor Impurity 302
Formula: C14H22ClN5O6S
423.87
RM-T031002
N-(5-amino-6-chloro-2-(propylsulfinyl)pyrimidin-4-yl)-N-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)nitrous amide

Ticagrelor Impurity 303
Formula: C8H15NO3
173.21
RM-T031003
(3aS,4S,6S,6aR)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol

Ticagrelor Impurity 304
Formula: C28H34F2N6O5S
604.67
RM-T031004
2-(((3aR,4S,6R,6aS)-6-(7-(((1S,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethyl acetate

Ticagrelor Impurity 305
Formula: C23H28F2N6O4S
522.57
RM-T031005
(1S,2S,3R,5S)-3-((3-((1S,2R)-2-(3,4-difluorophenyl)cyclopropyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 306
CAS:2724654-44-6
Formula: C10H19NO4 C4H8O6
217.27 152.10
RM-T031006
2-(((3aS,4S,6S,6aR)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol (2S,3R)-4-hydroperoxy-2,3-dihydroxybutanoate

Ticagrelor Impurity 307
CAS:2703957-62-2
Formula: C10H19NO4
217.27
RM-T031007
2-(((3aR,4S,6S,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol--2-(((3aS,4R,6R,6aR)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol (1/1)

Ticagrelor Impurity 308
CAS:42245-42-1
Formula: C11H12O4
208.21
RM-T031008
Methyl 3-(4-methoxyphenyl)oxirane-2-carboxylate

Ticagrelor Impurity 309
CAS:16546-01-3
Formula: C12H14O4
222.24
RM-T031009
Ethyl 3-(4-methoxyphenyl)oxirane-2-carboxylate

Ticagrelor Impurity 310
CAS:1822784-83-7
Formula: C12H12F2O2
226.22
RM-T031010
ethyl 2-(3,4-difluorophenyl)cyclopropane-1-carboxylate

Ticagrelor Impurity 311
CAS:1808068-84-9
Formula: C9H9ClFN
185.63
RM-T031011
(1R,2S)-2-(4-chloro-3-fluorophenyl)cyclopropan-1-amine/(1S,2R)-2-(4-chloro-3-fluorophenyl)cyclopropan-1-amine

Ticagrelor Impurity 312
Formula: C10H19NO4
217.27
RM-T031012
2-(((3aR,4R,6S,6aR)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Impurity 313
CAS:378236-67-0
Formula: C10H7F2N3O
223.18
RM-T031013
(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carbonyl azide

Ticagrelor Impurity 316
Formula: C23H27F2N7O5S
551.57
RM-T031016
(1S,2S,3R,5S)-3-(7-(((E)-2-(3,4-difluorophenyl)-3-nitrosoprop-1-en-1-yl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 325
Formula: C26H32F2N6O4S
562.64
RM-T031025
2-(((3aS,4R,6S,6aR)-6-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Impurity 326
Formula: C14H20ClN5O4S
389.86
RM-T031026
3-(7-chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 327
Formula: C23H28F2N6O4S
522.57
RM-T031027
(1S,2S,3S,5R)-3-(7-(((1S,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity 328
CAS:2245167-79-5
Formula: C21H24F2N6O3S
478.52
RM-T031028
(1S,2R,3S,4R)-4-(7-(((1S,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)cyclopentane-1,2,3-triol Chemical Formula: C21H24F2N6O3S Molecular Weight: 478.52

Ticagrelor Impurity 329
CAS:2714888-22-7
Formula: C23H30F2N6O4S
524.59
RM-T031029
rel-(1R,2R,3S,5R)-3-[7-Amino-1,2-dihydro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-[2-[[2-(3,4-difluorophenyl)cyclopropyl]oxy]ethoxy]-1,2-cyclopentanediol

TICAGRELOR IMPURITY 4
CAS:274693-53-7
Formula: C16H21NO5
307.34
RM-T030730
benzyl ((3aS,4R,6S,6aR)-6-hydroxy-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)carbamate

TICAGRELOR IMPURITY 50
Formula: C25H30F2N6O6S
580.6
RM-T030750
2-hydroxyethyl 2-(((1S,2S,3S,4R)-4-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,3-dihydroxycyclopentyl)oxy)acetate

TICAGRELOR IMPURITY 59
Formula: C23H28F2N6O4S
522.57
RM-T030759
(1S,2R,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICAGRELOR IMPURITY 6
Formula: C9H11ClFN
187.64
RM-T030732
2-(3-fluorophenyl)cyclopropanamine hydrochloride

TICAGRELOR IMPURITY 60
Formula: C23H28F2N6O4S
522.57
RM-T030760
(1R,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICAGRELOR IMPURITY 61
Formula: C15H20ClN5O3S
385.87
RM-T030761
(3aR,4S,6R,6aS)-6-(7-chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol

Ticagrelor Impurity 62(Az13265501)
CAS:2435586-23-3
Formula: C24H31FN6O4S2
550.67
RM-T030762
(1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(4-fluoro-3-(methylthio)phenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICAGRELOR IMPURITY 63
CAS:2227766-79-0
Formula: C9H9ClFN
185.63
RM-T030763
(1R,2S)-2-(3-chloro-4-fluorophenyl)cyclopropanamine

TICAGRELOR IMPURITY 64
Formula: C25H33FN6O5S
548.63
RM-T030764
(1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3-ethoxy-4-fluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICAGRELOR IMPURITY 65
Formula: C11H15ClFNO
231.69
RM-T030765
(1R,2S)-2-(3-ethoxy-4-fluorophenyl)cyclopropanamine hydrochloride

TICAGRELOR IMPURITY 66
CAS:1643378-48-6
Formula: C23H28F2N6O4S
522.57
RM-T030766
(1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(2,3-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICAGRELOR IMPURITY 68
Formula: C28H44N6O8S
624.75
RM-T030768
3-(((3aR,4S,6R,6aS)-6-((3-((3aS,4R,6S,6aR)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)

TICAGRELOR IMPURITY 69
Formula: C19H26ClN5O5S
471.96
RM-T030769
2-(((3aR,4S,6R,6aS)-6-(7-chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethyl acetate

TICAGRELOR IMPURITY 7
CAS:1823431-32-8
Formula: C7H9Cl2N3OS
254.14
RM-T030733
4,6-dichloro-2-(propylsulfinyl)pyrimidin-5-amine

TICAGRELOR IMPURITY 70
Formula: C34H50ClN9O8S2
812.4
RM-T030770
2-(((3aR,4S,6R,6aS)-6-((6-chloro-5-((3-((3aS,4R,6S,6aR)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dime

TICAGRELOR IMPURITY 71
Formula: C26H33F2N5O6S
581.63
RM-T030771
2-(((3aR,4S,6R,6aS)-6-((6-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-nitro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol

TICAGRELOR IMPURITY 72
CAS:1628340-74-8
Formula: C28H34F2N6O5S
604.67
RM-T030772
2-(((3aR,4S,6R,6aS)-6-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethyl acetate

TICAGRELOR IMPURITY 73
Formula: C23H31F2N5O4S
511.59
RM-T030773
(1S,2S,3R,5S)-3-((5-amino-6-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-2-(propylthio)pyrimidin-4-yl)amino)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICAGRELOR IMPURITY 74
CAS:274693-55-9
Formula: C10H19NO4
217.27
RM-T030774
2-(((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

TICAGRELOR IMPURITY 75
Formula: C9H9F2N
169.17
RM-T030775
(1R,2R)-2-(3,4-difluorophenyl)cyclopropan-1-amine--(1S,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine (1/1)

TICAGRELOR IMPURITY 76
Formula: C26H32F2N6O4S
562.63
RM-T030776
2-(((3aR,4S,6R,6aS)-6-(7-(((1S,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol

TICAGRELOR IMPURITY 77
Formula: C9H9F2N
169.17
RM-T030777
2-(3,4-difluorophenyl)cyclopropanamine

TICAGRELOR IMPURITY 78
CAS:155899-66-4
Formula: C8H15NO3
173.21
RM-T030778
(3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol

TICAGRELOR IMPURITY 79
CAS:1643378-46-4
Formula: C23H29FN6O4S
504.58
RM-T030779
(1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3-fluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICAGRELOR IMPURITY 8
CAS:1401318-10-2
Formula: C7H8Cl2N2S
223.12
RM-T030734
4,6-Dichloro-2-(propylthio)pyrimidine

TICAGRELOR IMPURITY 80
CAS:1006376-63-1
Formula: C8H6F2O
156.13
RM-T030780
(S)-2-(3,4-difluorophenyl)oxirane

TICAGRELOR IMPURITY 81
CAS:1006376-60-8
Formula: C8H7ClF2O
192.59
RM-T030781
(S)-2-Chloro-1-(3,4-difluorophenyl)ethanol

TICAGRELOR IMPURITY 82
CAS:1006376-61-9
Formula: C12H12F2O2
226.22
RM-T030782
(1R,2R)-Ethyl 2-(3,4-difluorophenyl)cyclopropanecarboxylate

Ticagrelor Impurity 83
CAS:2435586-40-4
Formula: C23H28F2N6O4S
522.57
RM-T030783
(1S,2S,3R,5S)-3-(7-(((1S,2S)-2-(3,4-difluorophenyl)cyclopropyl)aMino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICAGRELOR IMPURITY 84
CAS:2056269-94-2+N/A
Formula: C23H28F2N6O4S*2
522.57*2
RM-T030784
(1S,2S,3R,5S)-3-(7-(((1R,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol--(1S,2S,3R,5S)-3-(7-(((1S,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-

Ticagrelor Impurity 85
Formula: C17H17ClFNO3
337.77
RM-T030785
2-(3-chloro-4-fluorophenyl)cyclopropanamine (R)-2-hydroxy-2-phenylacetate

Ticagrelor Impurity 86
Formula: C9H9ClFN*C8H8O3
185.63*152.15
RM-T030786
2-(4-chloro-3-fluorophenyl)cyclopropanamine (R)-2-hydroxy-2-phenylacetate

Ticagrelor Impurity 87
Formula: C9H10FN*C8H8O
151.18*152.15
RM-T030787
2-(4-fluorophenyl)cyclopropanamine (R)-2-hydroxy-2-phenylacetate

TICAGRELOR IMPURITY 88
CAS:1414348-35-8
Formula: C9H9F2N
169.17
RM-T030788
(1R,2R)-2-(3,4-Difluorophenyl)cyclopropanamine

TICAGRELOR IMPURITY 89
CAS:1265919-24-1
Formula: C12H21NO5
259.3
RM-T030789
ethyl 2-(((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)acetate

TICAGRELOR IMPURITY 9
CAS:220241-60-1
Formula: C15H23ClN4O3S
374.89
RM-T030735
(3aR,4S,6R,6aS)-6-((5-amino-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol

TICAGRELOR IMPURITY 90
CAS:367-11-3
Formula: C6H4F2
114.09
RM-T030790
1,2-Difluorobenzene

TICAGRELOR IMPURITY 91
CAS:51336-95-9
Formula: C8H5ClF2O
190.57
RM-T030791
2-chloro-1-(3,4-difluorophenyl)ethanone

Ticagrelor Impurity 92
CAS:867-13-0
Formula: C8H17O5P
224.19
RM-T030792
Ethyl 2-(diethoxyphosphoryl)acetate

TICAGRELOR IMPURITY 93
Formula: C17H26ClN5O5S
447.94
RM-T030793
N-(5-amino-6-chloro-2-(propylthio)pyrimidin-4-yl)-N-((3aS,4R,6S,6aR)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)nitrous amide

TICAGRELOR IMPURITY 94
Formula: C23H28F2N6O5S
538.57
RM-T030794
(1S,2S,3R,5S)-3-(7-(((1S,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylsulfinyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICAGRELOR IMPURITY 95
Formula: C27H45N5O8S
599.74
RM-T030795
2,2'-(((3aR,3a'R,4S,4'S,6R,6aS,6'R,6a'S)-6,6'-((5-amino-2-(propylthio)pyrimidine-4,6-diyl)bis(azanediyl))bis(2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxole-6,4-diyl))bis(oxy))diethanol

TICAGRELOR IMPURITY 96
CAS:1643413-84-6
Formula: C9H9F2N
169.17
RM-T030796
(1R,2S)-2-(2,5-difluorophenyl)cyclopropanamine

TICAGRELOR IMPURITY 97
CAS:220352-50-1
Formula: C9H9F2N
169.17
RM-T030797
(1R,2S)-2-(3,5-difluorophenyl)cyclopropanamine

TICAGRELOR IMPURITY 98
CAS:1643413-83-5
Formula: C9H9F2N
169.17
RM-T030798
(1R,2S)-2-(2,4-difluorophenyl)cyclopropanamine

TICAGRELOR IMPURITY 99
CAS:1643413-85-7
Formula: C9H9F2N
169.17
RM-T030799
(1R,2S)-2-(2,6-difluorophenyl)cyclopropanamine

TICAGRELOR IMPURITY A (TICAGRELOR ENANTIOMER)
CAS:2096989-55-6
Formula: C23H28F2N6O4S
522.57
RM-T030701
(1R,2R,3S,5R)-3-(7-(((1S,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity B (Ticagrelor Isomer 2)
CAS:2435586-30-2
Formula: C23H28F2N6O4S
522.57
RM-T030702
(1R,2R,3S,5R)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICAGRELOR IMPURITY C (TICAGRELOR ISOMER 3)
CAS:2096989-56-7
Formula: C23H28F2N6O4S
522.57
RM-T030703
(1S,2S,3R,5S)-3-(7-(((1S,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICAGRELOR IMPURITY D(UL127)
CAS:274693-26-4
Formula: C26H32F2N6O4S
562.63
RM-T030704
2-(((3aR,4S,6R,6aS)-6-(7-(((1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol

TICAGRELOR IMPURITY E (UL133)
CAS:1788033-05-5
Formula: C23H28F2N6O4S
522.57
RM-T030705
(1S,2S,3R,5S)-3-((3-((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Impurity F(Az13232789)
CAS:1616703-93-5
Formula: C25H30F2N6O5S
564.6
RM-T030706
2-(((1S,2S,3S,4R)-4-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,3-dihydroxycyclopentyl)oxy)ethyl acetate

TICAGRELOR IMPURITY G
CAS:220347-05-7
Formula: C21H24F2N6O3S
478.52
RM-T030707
(1S,2R,3S,4R)-4-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)cyclopentane-1,2,3-triol

TICAGRELOR IMPURITY G-D7
Formula: C21H17D7F2N6O3S
485.56
RM-T031030
(1S,2R,3S,4R)-4-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-((propyl-d7)thio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)cyclopentane-1,2,3-triol

TICAGRELOR IMPURITY H (UL134)
CAS:1251765-07-7
Formula: C14H22N6O4S
370.43
RM-T030708
(1S,2S,3R,5S)-3-(7-Amino-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICAGRELOR IMPURITY I (UL136)
CAS:1445580-43-7
Formula: C14H21N5O5S
371.41
RM-T030709
(1S,2S,3R,5S)-3-(7-hydroxy-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICAGRELOR IMPURITY J
CAS:1402150-32-6
Formula: C14H23ClN4O4S
378.87
RM-T030710
(1S,2S,3R,5S)-3-((5-amino-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICAGRELOR IMPURITY K
CAS:2248538-63-6
Formula: C14H20ClN5O4S
389.86
RM-T030711
(1S,2S,3R,5S)-3-(7-Chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICAGRELOR IMPURITY L (MIXTURE OF DIASTEREOMERS)
CAS:1644461-85-7
Formula: C23H28F2N6O5S
538.57
RM-T030712
(1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylsulfinyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICAGRELOR IMPURITY M
CAS:274693-39-9
Formula: C23H28F2N6O6S
554.57
RM-T030713
(1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylsulfonyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICAGRELOR IMPURITY N
CAS:1643378-47-5
Formula: C23H29FN6O4S
504.58
RM-T030714
(1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(4-fluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICAGRELOR IMPURITY O
Formula: C17H25ClN4O6S
448.92
RM-T030715
2-{[(3aR,4S,6R,6aS)-6-{[6-chloro-5-nitro-2-(propylsulfanyl)pyrimidin-4-yl]amino}-2,2-dimethyl-hexahydrocyclopenta[d][1,3]dioxol-4-yl]oxy}ethan-1-ol

TICAGRELOR IMPURITY R
CAS:2205903-73-5
Formula: C28H42ClN9O8S2
732.28
RM-T030718
(1S,2S,3R,5S)-3-((6-Chloro-5-((3-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-2-(propylthio)pyrimidin-4-yl)amino)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICAGRELOR IMPURITY S
CAS:2165799-36-8
Formula: C10H19NO4
217.26
RM-T030719
2-(((3aS,4S,6R,6aR)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol

TICAGRELOR IMPURITY T
CAS:1644461-81-3
Formula: C20H22F2N6O5
464.43
RM-T030720
(1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-hydroxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICAGRELOR IMPURITY U
CAS:145783-15-9
Formula: C7H9Cl2N3S
238.14
RM-T030721
4,6-dichloro-2-(propylthio)pyrimidin-5-amine

Ticagrelor Impurity W
CAS:2518331-26-3
Formula: C7H8ClN3O2S
233.68
RM-T030723
4-Chloro-5-nitro-2-(propylthio)pyrimidine

TICAGRELOR IMPURITY X
Formula: C8H11N3O3S
229.26
RM-T030724
4-Methoxy-5-nitro-2-(propylthio)pyrimidine

Ticagrelor Impurity Z
CAS:376608-75-2
Formula: C17H24ClN5O4S
429.92
RM-T030726
2-(((3aR,4S,6R,6aS)-6-(7-chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Ticagrelor Nitroso Impurity 314
Formula: C21H33N7O9S
559.6
RM-T031014
N-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)-N-(3-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)nitrous amide

Ticagrelor Nitroso Impurity 315
Formula: C21H23F2N7O4S
507.52
RM-T031015
N-(2-(3,4-difluorophenyl)cyclopropyl)-N-(5-(propylthio)-3-((1R,2S,3S,4R)-2,3,4-trihydroxycyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)nitrous amide

Ticagrelor Nitroso Impurity 317
Formula: C17H26ClN5O5S
447.94
RM-T031017
N-(5-amino-6-chloro-2-(propylthio)pyrimidin-4-yl)-N-((3aR,4R,6S,6aS)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)nitrous amide

Ticagrelor Nitroso Impurity 318
Formula: C23H27F2N7O5S
551.57
RM-T031018
N-((1S,2R)-2-(3,4-difluorophenyl)cyclopropyl)-N-(3-((1S,2R,3R,4R)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)nitrous amide

Ticagrelor Nitroso Impurity 319
Formula: C21H23F2N7O4S
507.52
RM-T031019
N-((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)-N-(5-(propylthio)-3-((1S,2S,3R,4S)-2,3,4-trihydroxycyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)nitrous amide

Ticagrelor Nitroso Impurity 322
Formula: C17H26ClN5O5S
447.94
RM-T031022
N-(5-amino-6-chloro-2-(propylthio)pyrimidin-4-yl)-N-((3aS,4R,6S,6aR)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)nitrous amide

Ticagrelor Nitroso Impurity 33
Formula: C26H31F2N7O5S
591.63
RM-T031023
N-((1R,2R)-2-(3,4-difluorophenyl)cyclopropyl)-N-(3-((3aS,4R,6S,6aR)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)nitrous amide

Ticagrelor Nitroso Impurity 34
Formula: C23H27F2N7O5S
551.57
RM-T031024
N-((1R,2R)-2-(3,4-difluorophenyl)cyclopropyl)-N-(3-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)nitrous amide

Ticagrelor Related Compound Gà¦
CAS:220352-38-5
Formula: C9H9F2N
169.17
RM-T030757
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine

TICAGRELOR RELATED COMPOUND I
CAS:2165881-71-8
Formula: C10H19NO4
217.26
RM-T030751
2-(((3aS,4R,6S,6aR)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol

TICAGRELOR RELATED COMPOUND II
CAS:274693-54-8
Formula: C18H25NO6
351.39
RM-T030752
benzyl ((3aR,4S,6R,6aS)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)carbamate

Ticagrelor Related Compound Iii
CAS:1345413-20-8
Formula: C9H9F2N
169.17
RM-T030753
(1S,2R)-2-(3,4-difluorophenyl)cyclopropan-1-amine

Ticagrelor Related Compound Iv
Formula: C14H17F2NO2
269.29
RM-T030754
tert-butyl ((1S,2R)-2-(3,4-difluorophenyl)cyclopropyl)carbamate

TICAGRELOR RELATED COMPOUND V
Formula: C17H25ClN4O6S
448.92
RM-T030755
2-(((3aR,4S,6R,6aS)-6-((6-chloro-5-nitro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol

TICAGRELOR-D7
CAS:1265911-55-4
Formula: C23H21D7F2N6O4S
529.61
RM-T030914
(1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-((propyl-d7)thio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

TICARCILLIN DISODIUM
CAS:4697-14-7
Formula: C15H14N2Na2O6S2
428.39
RM-T030300
Disodium (2S,5R,6R)-6-[[(2RS)-2-carboxylato-2-(thiophen-3-yl)acetyl] amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; sodium (2S,5R,6R)-6-(2-carboxylato-2-(thiophen-3-yl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabi

TICARCILLIN EP IMPURITY A
CAS:36041-93-7
Formula: C14H16N2O4S2
340.42
RM-T030301
(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[[(thiophen-3-yl)acetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

TICARCILLIN EP IMPURITY B
CAS:6964-21-2
Formula: C6H6O2S
142.18
RM-T030302
3-Thiopheneacetic acid

TICARCILLIN EP IMPURITY C
CAS:21080-92-2
Formula: C7H6O4S
186.19
RM-T030303
2-(Thiophen-3-yl)propanedioic acid

TICARCILLIN EP IMPURITY D
Formula: C15H18N2O7S2
402.44
RM-T030304
(4S)-2-[Carboxy[[2-carboxy-2-(thiophen-3-yl)acetyl]amino]methyl]-5,5-dimethylthiazolidine-4-carboxylic acid

TICARCILLIN EP IMPURITY E
CAS:2747990-79-8
Formula: C14H18N2O5S2
358.43
RM-T030305
(4S)-2-((2-carboxy-2-(thiophen-3-yl)acetamido)methyl)-5,5-dimethylthiazolidine-4-carboxylic acid

Ticarcillin Impurity 10
CAS:50530-49-9
Formula: C7H6O4S
186.18
RM-T030310
2-(thiophen-2-yl)malonic acid

Ticarcillin Impurity 11
CAS:34787-01-4
Formula: C15H16N2O6S2
384.42
RM-T030311
(2S,5R,6R)-6-((R)-2-carboxy-2-(thiophen-3-yl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Ticarcillin Impurity 12
Formula: C15H16N2O8S2
416.42
RM-T030312
(2S,5R,6R)-6-(2-carboxy-2-(thiophen-3-yl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide

TICLOPIDINE HYDROCHLORIDE
CAS:53885-35-1
Formula: C14H14ClNS HCl
263.79 36.46
RM-T091600
5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride

Ticlopidine Hydrochloride EP Impurity A
CAS:272-14-0
Formula: C7H5NS
135.19
RM-T091601
Thieno[3,2-c]pyridine

Ticlopidine Hydrochloride EP Impurity B
CAS:68559-60-4
Formula: C7H7NOS
153.2
RM-T091602
6,7-dihydrothieno[3,2-c]pyridin-4(5H)-one

Ticlopidine Hydrochloride EP Impurity C
CAS:89-97-4
Formula: C7H8ClN
141.6
RM-T091603
(2-chlorophenyl)methanamine

Ticlopidine Hydrochloride EP Impurity D
CAS:55142-78-4
Formula: C14H15NS
229.34
RM-T091604
5-Benzyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine

Ticlopidine Hydrochloride EP Impurity E
CAS:53885-64-6
Formula: C14H11ClNS*Cl
260.76*35.45
RM-T091605
5-(2-chlorobenzyl)thieno[3,2-c]pyridin-5-ium chloride

Ticlopidine Hydrochloride EP Impurity F
CAS:62019-75-4
Formula: C14H14ClNS
263.79
RM-T091606
6-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine

Ticlopidine Hydrochloride EP Impurity G
CAS:55142-86-4
Formula: C14H14ClNS
263.79
RM-T091607
5-(3-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine

Ticlopidine Hydrochloride EP Impurity H
CAS:55157-56-7
Formula: C14H14ClNS
263.79
RM-T091608
5-(4-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine

Ticlopidine Hydrochloride EP Impurity I
CAS:69061-17-2
Formula: C13H14ClNS
251.77
RM-T091609
N-(2-chlorobenzyl)-2-(thiophen-2-yl)ethanamine

Ticlopidine Hydrochloride EP Impurity J
CAS:108896-78-2
Formula: C16H18Cl2N2
309.23
RM-T091610
N1,N2-bis(2-chlorobenzyl)ethane-1,2-diamine

Ticlopidine Hydrochloride EP Impurity K
Formula: C24H24Cl2N2S
443.43
RM-T091611
2,8-bis(2-chlorobenzyl)-1,2,3,4,6,7,8,9-octahydrothieno[3,2-c:4,5-c']dipyridine

Ticlopidine Hydrochloride EP Impurity L
CAS:68559-55-7
Formula: C14H12ClNOS
277.77
RM-T091612
5-(2-Chlorobenzyl)-6,7-dihydrothieno[3,2-c]pyridin-4(5H)-one

Ticlopidine Hydrochloride Impurity 13
Formula: C13H14O3S2
282.38
RM-T091613
2-(thiophen-2-yl)ethyl 3-methylbenzenesulfonate

Ticlopidine Hydrochloride Impurity 14
Formula: C13H14O3S2
282.38
RM-T091614
2-(thiophen-2-yl)ethyl 2-methylbenzenesulfonate

TICLOPIDINE HYDROCHLORIDE IMPURITY 15
CAS:138956-81-7
Formula: C14H12ClN
229.7
RM-T091615
(E)-N-benzylidene-1-(2-chlorophenyl)methanamine

TIGECYCLINE
CAS:220620-09-7
Formula: C29H39N5O8
585.65
RM-T070500
(4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

Tigecycline EP Impurity A(Tigecycline Epimer)
CAS:1422262-97-2
Formula: C29H39N5O8
585.65
RM-T070501
(4R,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

Tigecycline EP Impurity B(9-Aminominocycline)
CAS:149934-19-0
Formula: C23H28N4O7
472.49
RM-M140313
(4S,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

Tigecycline EP Impurity D(Tigecycline Open Ring)
CAS:1138343-10-8
Formula: C29H37N5O10
615.64
RM-T070503
(3S,4R)-7-(2-(tert-butylamino)acetamido)-3-(4-carbamoyl-2-(dimethylamino)-3,5,6-trihydroxybenzyl)-5-(dimethyliminio)-1,4-dihydroxy-8-oxo-3,4,5,8-tetrahydronaphthalene-2-carboxylate

TIGECYCLINE IMPURITY 11
Formula: C29H39N5O9
601.66
RM-T070511
(4S,4aS,5aR,11aS,12aR)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-3,10,11a,12a-tetrahydroxy-1,11,12-trioxo-1,4,4a,5,5a,6,11,11a,12,12a-decahydrotetracene-2-carboxamide

Tigecycline Impurity 15; N-Nitroso-Desmethyl-Eravacycline
Formula: C26H28FN5O9
573.53
RM-T070515
(4S,4aS,5aR,12aS)-7-fluoro-3,10,12,12a-tetrahydroxy-4-(methyl(nitroso)amino)-1,11-dioxo-9-(2-(pyrrolidin-1-yl)acetamido)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

TIGECYCLINE IMPURITY 16
Formula: C29H39N5O10
617.66
RM-T070516
(3S)-7-(2-(tert-butylamino)acetamido)-3-(4-carbamoyl-2-(dimethylamino)-3,5,6-trihydroxybenzyl)-5-(dimethylamino)-1,4,8-trihydroxy-3,4-dihydronaphthalene-2-carboxylic acid

Tigecycline Impurity 17; Eravacycline
CAS:1207283-85-9
Formula: C27H31FN4O8
558.56
RM-T070517
(4S,4aS,5aR,12aS)-4-(dimethylamino)-7-fluoro-3,10,12,12a-tetrahydroxy-1,11-dioxo-9-(2-(pyrrolidin-1-yl)acetamido)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

TIGECYCLINE IMPURITY 18
CAS:866602-58-6
Formula: C29H39N5O9
601.66
RM-T070518
(4S,4aS,5aR,12aR)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-3,10,11a,12a-tetrahydroxy-1,11,12-trioxo-1,4,4a,5,5a,6,11,11a,12,12a-decahydrotetracene-2-carboxamide

TIGECYCLINE IMPURITY 19
Formula: C27H32N4O9
556.57
RM-T070519
(1S,4aR,4bR,10aR)-7-(2-(tert-butylamino)acetamido)-9-(dimethylamino)-1,4,4a,6-tetrahydroxy-2,5,12-trioxo-1,2,4a,5,10,10a,11,11a-octahydro-1,4b-methanobenzo[b]fluorene-3-carboxamide

Tigecycline Impurity 2(Tigecycline Quinone Analog)
CAS:1268494-46-7
Formula: C26H32N4O8
528.55
RM-T070502
(S)-4-((6-(2-(tert-butylamino)acetamido)-8-(dimethylamino)-5-hydroxy-4-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)methyl)-2,5-dihydroxy-3,6-dioxocyclohexa-1,4-dienecarboxamide

TIGECYCLINE IMPURITY 20
CAS:957187-94-9
Formula: C23H28N4O7
472.5
RM-T070520
(4R,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

TIGECYCLINE IMPURITY 21
Formula: C23H28N4O8
488.5
RM-T070521
(4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

TIGECYCLINE IMPURITY 22
Formula: C23H29N5O7
487.51
RM-T070522
(4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

Tigecycline Impurity 4(Tigecycline 12-Oxo-11-Hydroxy)
CAS:1633815-62-9
Formula: C29H37N5O8
583.63
RM-T070504
(4S,4aS,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,11,12a-hexahydrotetracene-2-carboxamide

TIGECYCLINE IMPURITY 5
Formula: C27H32N4O9
556.56
RM-T070505
(1S,10aR)-7-(2-(tert-butylamino)acetamido)-9-(dimethylamino)-1,4,4a,6-tetrahydroxy-2,5,12-trioxo-1,2,4a,5,10,10a,11,11a-octahydro-1,4b-methanobenzo[b]fluorene-3-carboxamide

TIGECYCLINE IMPURITY 6
Formula: C29H39N5O10
617.65
RM-T070506
(3S,4R)-7-(2-(tert-butylamino)acetamido)-3-(4-carbamoyl-2-(dimethylamino)-3,5,6-trihydroxybenzyl)-5-(dimethyliminio)-1,4,8-trihydroxy-3,4,5,8-tetrahydronaphthalene-2-carboxylate

Tigecycline Impurity 7(Tigecycline Tricyclic Analog)
CAS:1268494-40-1
Formula: C27H32N4O9
556.57
RM-T070507
(1S,4aR,4bR,10aR,11aS)-7-(2-(tert-butylamino)acetamido)-9-(dimethylamino)-1,4,4a,6-tetrahydroxy-2,5,12-trioxo-1,2,4a,5,10,10a,11,11a-octahydro-1,4b-methanobenzo[b]fluorene-3-carboxamide

TIGECYCLINE IMPURITY 8
CAS:488820-34-4
Formula: C24H30N4O7
486.52
RM-T070508
(4S,4aS,5aR,12aS)-9-(aminomethyl)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

TIGECYCLINE IMPURITY 9
Formula: C24H28F2N4O7
522.5
RM-T070509
(4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-9-fluorocarbonyl-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

TIGECYCLINE-D9
Formula: C29H30D9N5O8
594.7
RM-T070510
Tigecycline -D9

TILDIPIROSIN
CAS:328898-40-4
Formula: C41H71N3O8
734.03
RM-T010400
(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4S,5S,6R)-4-(dimethylamino)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-5,9,13-trimethyl-7-(2-piperidin-1-ylethyl)-15-(piperidin-1-ylmethyl)-1-oxacyclohexadeca-11,13-diene-2,10-dione

TILMICOSIN
CAS:108050-54-0
Formula: C46H80N2O13
869.13
RM-T121900
20-Deoxo-20-(3,5-dimethyl-1-piperidinyl)desmycosin

TILMICOSIN-D3
Formula: C46H77D3N2O13
872.17
RM-T121901
(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-(((2R,3R,4S,5S,6R)-3,5-dihydroxy-6-methyl-4-(methyl(methyl-d3)amino)tetrahydro-2H-pyran-2-yl)oxy)-7-(2-((3S,5R)-3,5-dimethylpiperidin-1-yl)ethyl)-16-ethyl-4-hydroxy-15-((((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dim

TILORONE
CAS:27591-97-5
Formula: C25H34N2O3
410.56
RM-T321000
2,7-bis(2-(diethylamino)ethoxy)-9H-fluoren-9-one

TIMIPERONE
CAS:57648-21-2
Formula: C22H24FN3OS
397.51
RM-T328000
4-[4-(2,3-Dihydro-2-thioxo-1H-benzimidazol-1-yl)-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone; Celmanil; DD 3480; Timeperone; Timiperone; Tolopelon; 1-(4-fluorophenyl)-4-(4-(2-thioxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)butan

TIMOLOL MALEATE
CAS:26921-17-5
Formula: C13H24N4O3S C4H4O4
316.42 116.07
RM-T131200
(S)-1-(tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol maleate

Timolol Maleate EP Impurity A
CAS:26839-77-0
Formula: C17H28N4O7S
432.49
RM-T131201
(R)-1-(tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol maleate

Timolol Maleate EP Impurity B
CAS:59697-06-2
Formula: C13H24N4O3S
316.42
RM-T131202
3-(tert-butylamino)-2-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-1-ol

TIMOLOL MALEATE EP IMPURITY C
CAS:610271-56-2
Formula: C19H31N7O4S2
485.62
RM-T131203
N-(tert-butyl)-2,3-bis((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-1-amine

TIMOLOL MALEATE EP IMPURITY D
CAS:30165-97-0
Formula: C6H9N3O2S
187.22
RM-T131204
4-morpholino-1,2,5-thiadiazol-3-ol

TIMOLOL MALEATE EP IMPURITY E
CAS:1026075-53-5
Formula: C17H26N4O6S
414.48
RM-T131205
(S,Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid

Timolol Maleate EP Impurity F
CAS:30165-96-9
Formula: C6H8ClN3OS
205.67
RM-T131206
4-(4-Chloro-1,2,5-thiadiazol-3-yl)morpholine

TIMOLOL MALEATE EP IMPURITY G
CAS:75202-36-7
Formula: C6H9N3O3S
203.22
RM-T131207
4-morpholino-1,2,5-thiadiazol-3(2H)-one 1-oxide

TIMOLOL MALEATE EP IMPURITY H
CAS:158636-97-6
Formula: C13H24N4O3S
316.42
RM-T131208
2-(3-(tert-butylamino)-2-hydroxypropyl)-4-morpholino-1,2,5-thiadiazol-3(2H)-one

Timolol Maleate EP Impurity I
CAS:2469037-77-0
Formula: C11H20N4O3S
288.37
RM-T131209
1-(ethylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol

Timolol Maleate EP Impurity J
Formula: C16H32N4O4S
376.51
RM-T131210
3,3'-((1,2,5-thiadiazole-3,4-diyl)bis(oxy))bis(1-(tert-butylamino)propan-2-ol)

TIMOLOL MALEATE IMPURITY 11
CAS:1391068-18-0
Formula: C19H31N7O4S2
485.62
RM-T131211
(S)-N-(tert-butyl)-2,3-bis((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-1-amine

TIMOLOL MALEATE IMPURITY 12
CAS:158636-96-5
Formula: C13H24N4O3S
316.42
RM-T131212
(S)-3-(tert-butylamino)-2-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-1-ol

Timolol Maleate Impurity 13
Formula: C9H13N3O5S
275.28
RM-T131213
(R)-2-hydroxy-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propanoic acid

Timolol Maleate Impurity 14
Formula: C16H26N4O4S
370.47
RM-T131214
(S)-1-(tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-yl acrylate

Timolol Maleate Impurity 15
Formula: C13H24N4O2S2
332.48
RM-T131215
(S)-1-(tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)thio)propan-2-ol

Timolol Maleate Impurity 16
Formula: C13H24N4O4S
332.42
RM-T131216
3-((R)-3-(tert-butylamino)-2-hydroxypropoxy)-4-morpholino-1,2,5-thiadiazole 1-oxide

Timolol Maleate Impurity 17
Formula: C13H24N4O3S
316.42
RM-T131217
(R)-1-(tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol

Timolol Maleate Impurity 19
CAS:214691-24-4
Formula: C6H9N3OS
171.22
RM-T131219
4-(1,2,5-thiadiazol-3-yl)morpholine

Timolol Maleate Impurity 20
Formula: C9H15N3O4S
261.3
RM-T131220
(S)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propane-1,2-diol

Timolol Maleate Impurity 21
Formula: C9H13N3O3S
243.28
RM-T131221
(R)-4-(4-(oxiran-2-ylmethoxy)-1,2,5-thiadiazol-3-yl)morpholine

Timolol Maleate Impurity 22
Formula: C15H22N6O5S2
430.5
RM-T131222
1,3-bis((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol

Timolol Maleate Impurity 23
Formula: C9H14ClN3O3S
279.74
RM-T131223
(R)-1-chloro-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol

Timolol Maleate Impurity 24
Formula: C22H37N7O6S2
559.7
RM-T131224
3,3'-(tert-butylazanediyl)bis(1-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol)

Timolol Maleate Impurity 25
Formula: C11H20N4O3S
288.37
RM-T131225
(S)-1-(ethylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol

Timolol Maleate Impurity 26
CAS:69500-53-4
Formula: C9H13N3O3S
243.28
RM-T131226
(S)-4-(4-(oxiran-2-ylmethoxy)-1,2,5-thiadiazol-3-yl)morpholine

Timolol Maleate Impurity 27
Formula: C13H24N4O2S2
332.48
RM-T131227
1-(tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)thio)propan-2-ol

Timolol Maleate Impurity 29
CAS:30315-46-9
Formula: C7H17NO2
147.22
RM-T131229
(S)-3-(tert-butylamino)propane-1,2-diol

Timolol Maleate Impurity 30
Formula: C14H21NO2
235.33
RM-T131230
((5S)-3-(tert-butyl)-2-phenyloxazolidin-5-yl)methanol

Timolol Maleate Nitroso Impurity 28
Formula: C7H16N2O3
176.22
RM-T131228
N-(tert-butyl)-N-(2,3-dihydroxypropyl)nitrous amide

Timolol Maleate Nitroso Impurity 31
Formula: C7H16N2O3
176.22
RM-T131231
(S)-N-(tert-butyl)-N-(2,3-dihydroxypropyl)nitrous amide

TIMOSAPONIN A III
CAS:41059-79-4
Formula: C39H64O13
740.93
RG-T010620
Timosaponine A III; Filiferin B; (3+¦,5+¦,25S)-Spirostan-3-yl 2-O-+¦-D-glucopyranosyl-+¦-D-galactopyranoside; (2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(((2aR,4S,5'S,6aS,6bS,8aS,8bR,9S,10R,11aS,12aS,12bR)-5',6a,8a,

TIMOSAPONIN B III
CAS:142759-74-8
Formula: C45H74O18
903.07
RG-T010621
Anemarrhenasaponin IV; Pseudoprototimosaponin A III; Timosaponin B; (2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(((2aR,4S,6aS,6bS,8aS,8bS,11aS,12aS,12bR)-6a,8a,9-trimethyl-10-((S)-3-methyl-4-(((2R,3R,4S,5S,6R)-3,

Timtec-Bb Sbb005357
CAS:7526-77-4
Formula: C6H8N2O2
140.14
RG-A261467
5-(propan-2-ylidene)imidazolidine-2,4-dione

TINIDAZOLE
CAS:19387-91-8
Formula: C8H13N3O4S
247.27
RM-T140400
1-(2-(ethylsulfonyl)ethyl)-2-methyl-5-nitro-1H-imidazole

TINIDAZOLE EP IMPURITY B
CAS:25459-12-5
Formula: C8H13N3O4S
247.27
RM-T140402
1-(2-(Ethylsulfonyl)ethyl)-2-methyl-4-nitro-1H-imidazole

Tinidazole Impurity 10
Formula: C8H11N3O6S
277.25
RM-T140410
1-(2-(ethylsulfonyl)ethyl)-5-nitro-1H-imidazole-2-carboxylic acid

TINIDAZOLE IMPURITY 11
Formula: C4H6N2O
98.1
RM-T140411
2-methyl-1H-imidazole 3-oxide

TINIDAZOLE IMPURITY 12
CAS:159790-76-8
Formula: C7H11N3O4S
233.24
RM-T140412
1-(2-(ethylsulfonyl)ethyl)-5-nitro-1H-imidazole

TINIDAZOLE IMPURITY 13
CAS:159790-77-9
Formula: C7H11N3O4S
233.24
RM-T140413
1-(2-(ethylsulfonyl)ethyl)-4-nitro-1H-imidazole

TINIDAZOLE IMPURITY 14
CAS:19387-94-1
Formula: C7H11N3O4S
233.24
RG-A262046
2-methyl-1-(2-(methylsulfonyl)ethyl)-5-nitro-1H-imidazole

TINIDAZOLE IMPURITY 15
Formula: C8H11N3O5S
261.25
RM-T140415
1-(2-(ethylsulfonyl)ethyl)-5-nitro-1H-imidazole-2-carbaldehyde

TINIDAZOLE IMPURITY 16
Formula: C8H11N3O6S
277.25
RM-T140416
1-(2-(ethylsulfonyl)ethyl)-2-formyl-5-nitro-1H-imidazole 3-oxide

Tinidazole Impurity 17
Formula: C8H13N3O5S
263.27
RM-T140417
1-(2-(ethylsulfonyl)ethyl)-2-methyl-5-nitro-1H-imidazole 3-oxide

Tinidazole Impurity 18
Formula: C8H13N3O5S
263.27
RM-T140418
1-(2-(ethylsulfonyl)ethyl)-2-methyl-5-nitro-1H-imidazole 1-oxide

Tinidazole Impurity 19
Formula: C6H11NO5S
209.22
RM-T140419
2-((2-(ethylsulfonyl)ethyl)amino)-2-oxoacetic acid

Tinidazole Impurity 20
CAS:79318-98-2
Formula: C8H14N2O2S
202.27
RM-T140420
1-(2-(ethylsulfonyl)ethyl)-2-methyl-1H-imidazole

Tinidazole Impurity 21
Formula: C6H7Cl2N3O2
224.04
RM-T140421
4-chloro-1-(2-chloroethyl)-2-methyl-5-nitro-1H-imidazole

Tinidazole Impurity 22
Formula: C7H11N3O2S
201.24
RM-T140422
1-(2-(ethylthio)ethyl)-4-nitro-1H-imidazole

Tinidazole Impurity 23
Formula: C7H11N3O2S
201.24
RM-T140423
1-(2-(ethylthio)ethyl)-5-nitro-1H-imidazole

Tinidazole Impurity 24
Formula: C8H18OS2
194.35
RM-T140424
(oxybis(ethane-2,1-diyl))bis(ethylsulfane)

TINIDAZOLE IMPURITY 3
CAS:28795-33-7
Formula: C8H13N3O2S
215.27
RM-T140403
1-(2-(Ethylthio)ethyl)-2-methyl-5-nitro-1H-imidazole

TINIDAZOLE IMPURITY 4
CAS:13230-19-8
Formula: C8H13N3O2S
215.27
RM-T140404
1-(2-(Ethylthio)ethyl)-2-methyl-4-nitro-1H-imidazole

TINIDAZOLE IMPURITY 5
CAS:110-77-0
Formula: C4H10OS
106.19
RM-T140405
2-(ethylthio)ethanol

TINIDAZOLE IMPURITY 6
CAS:2376335-05-4
Formula: C8H13N3O3S
231.27
RM-T140406
1-(2-(ethylsulfinyl)ethyl)-2-methyl-5-nitro-1H-imidazole

Tinidazole Impurity 7
Formula: C8H13N3O4S
247.27
RM-T140407
(Z)-1-(2-(ethylsulfonyl)ethyl)-4-(hydroxyimino)-2-methyl-1H-imidazol-5(4H)-one

TINIDAZOLE IMPURITY 8
CAS:140165-54-4
Formula: C8H13N3O4S
247.27
RM-T140408
N-(2-(ethylsulfonyl)ethyl)-5-methyl-1,2,4-oxadiazole-3-carboxamide

TINIDAZOLE IMPURITY 9
CAS:140165-55-5
Formula: C6H12N2O4S
208.24
RM-T140409
N1-(2-(ethylsulfonyl)ethyl)oxalamide

TINIDAZOLE IMPURITY A
CAS:351990-51-7
Formula: C4H3N3O4
157.08
RM-T140401
5-Nitro-1H-imidazole-2-carboxylic acid

TINOSORB A 2B
CAS:31274-51-8
Formula: C39H27N3
537.67
RG-T010900
2,4,6-tri([1,1'-biphenyl]-4-yl)-1,3,5-triazine

Tiocloxacillin;Cloxacillin Sodium Impurity 7
CAS:5053-36-1
Formula: C19H18ClN3O4S2
451.95
RM-C651207
(2R,5R,6R)-6-(3-(2-chlorophenyl)-5-methylisoxazole-4-carboxamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carbothioic S-acid

TIOCONAZOLE
CAS:65899-73-2
Formula: C16H13Cl3N2OS
387.71
RM-T090800
1-[(2RS)-2-[(2-Chlorothiophen-3-yl)methoxy]-2-(2,4- dichlorophenyl)ethyl]-1H-imidazole

Tioconazole EP Impurity A
Formula: C16H14Cl2N2OS
353.27
RM-T090801
1-[(2RS)-2-(2,4-dichlorophenyl)-2- [(thiophen-3-yl)methoxy]ethyl]-1H-imidazole

Tioconazole EP Impurity B
CAS:119386-75-3
Formula: C16H12Cl4N2OS
422.16
RM-T090802
1-[(2RS)-2-(2,4-dichlorophenyl)-2-[(2,5- dichlorothiophen-3-yl)methoxy]ethyl]-1H-imidazole

TIOCONAZOLE EP IMPURITY C
Formula: C16H12BrCl3N2OS
466.61
RM-T090803
1-[(2RS)-2-[(5-bromo-2-chlorothiophen- 3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole

TIOPRONIN
CAS:1953-02-2
Formula: C5H9NO3S
163.19
RM-T151600
2-(2-mercaptopropanamido)acetic acid

TIOPRONIN 13CD3
CAS:1189695-13-3
Formula: C413CH6D3NO3S
167.2
RM-T151608
(2-mercaptopropanoyl-3,3,3-d3)glycine-2-13C

TIOPRONIN IMPURITY 1
Formula: C7H13NO3S
191.25
RM-T151611
ethyl (S)-(2-mercaptopropanoyl)glycinate

Tiopronin Impurity 7
CAS:21301-10-0
Formula: C5H9NO4S
179.19
RM-T151607
(carboxymethyl)cysteine; DL-Cysteine, N-(carboxymethyl)-

TIOPRONIN IMPURITY A
CAS:85038-45-5
Formula: C5H8ClNO3
165.57
RM-T151601
2-Chloropropionylglycine

TIOPRONIN IMPURITY B
CAS:79-42-5
Formula: C3H6O2S
106.14
RM-T151602
2-mercaptopropanoic acid

TIOPRONIN IMPURITY C
CAS:21709-90-0
Formula: C5H9NO3
131.13
RM-T151603
2-propionamidoacetic acid

TIOPRONIN IMPURITY D
CAS:21269-37-4
Formula: C10H16N2O6S2
324.37
RM-T151604
2,2'-((2,2'-disulfanediylbis(propanoyl))bis(azanediyl))diacetic acid

TIOPRONIN IMPURITY E
CAS:177219-40-8
Formula: C11H20N2O2
212.29
RM-T151605
1-pentanamidocyclopentanecarboxamide

TIOPRONIN SULFONE
Formula: C5H9NO5S
195.19
RM-T151609
(2-hydrosulfonylpropanoyl)glycine

TIOPRONIN SULFOXIDE
Formula: C5H9NO4S
179.19
RM-T151606
2-(2-hydrosulfinylpropanamido)acetic acid

TIOTROPIUM BROMIDE
CAS:136310-93-5
Formula: C19H22NBrO4S2
472.42
RM-T201600
(1R,2R,4S,5S,7s)-7-(2-Hydroxy-2,2-di(thiophen-2-yl)acetoxy)-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-9-ium bromide

Tiotropium Bromide EP Impurity G-D3
Formula: C9H13D3BrNO2
253.15
RM-T201627
Tiotropium Bromide EP Impurity G-d3

TIOTROPIUM BROMIDE EP IMPURITY H
CAS:845870-40-8
Formula: C9H16BrNO2
250.13
RM-T201608
(1s,3RS,4RS,5RS,7SR)-4-hydroxy-6,6-dimethyl-2-oxa-6azoniatricyclo[3.3.1.03,7]nonanebromide

TIOTROPIUM BROMIDE EP IMPURITY H BROMIDE
CAS:1044148-31-3
Formula: C9H16NO2 Br
170.23 79.90
RM-T201631
(2R,3aS,5R,6R,6aR)-6-hydroxy-4,4-dimethylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-4-ium (2S,3aR,5S,6S,6aS)-6-hydroxy-4,4-dimethylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-4-ium bromide

Tiotropium Bromide EP Impurity H-D3
Formula: C9H13D3BrNO2
253.15
RM-T201619
Tiotropium Bromide EP Impurity H-d3

TIOTROPIUM BROMIDE IMPURITY 12
CAS:498-46-4
Formula: C8H13NO2
155.19
RM-T201612
(1R,2R,4S,5S,7r)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol

TIOTROPIUM BROMIDE IMPURITY 13
CAS:1459721-06-2
Formula: C18H19NO4S2
377.48
RM-T201613
(2R,3aR,5S)-4-methylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-6-yl 2-hydroxy-2,2-di(thiophen-2-yl)acetate

TIOTROPIUM BROMIDE IMPURITY 14
Formula: C14H10O2S3
306.42
RM-T201614
2-hydroxy-1,2,2-tri(thiophen-2-yl)ethanone

TIOTROPIUM BROMIDE IMPURITY 15
Formula: C19H22BrNO4S2
472.42
RM-T201615
(2R,3aR,5S)-6-(2-hydroxy-2,2-di(thiophen-2-yl)acetoxy)-4,4-dimethylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-4-ium bromide

TIOTROPIUM BROMIDE IMPURITY 16
CAS:1978292-75-9
Formula: C19H22BrNO4S2
472.42
RM-T201616
(1R,2R,4S,5S,7r)-7-(2-hydroxy-2-(thiophen-2-yl)-2-(thiophen-3-yl)acetoxy)-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-9-ium bromide

TIOTROPIUM BROMIDE IMPURITY 17
Formula: C9H16BrNO2
250.13
RM-T201617
(2S,3aR,5S)-6-hydroxy-4,4-dimethylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-4-ium bromide

TIOTROPIUM BROMIDE IMPURITY 18
CAS:320347-97-5
Formula: C17H19NO3S2
349.47
RM-T201618
(R)-quinuclidin-3-yl 2-hydroxy-2,2-di(thiophen-2-yl)acetate

Tiotropium Bromide Impurity 21
Formula: C19H21ClINO3S2
537.86
RM-T201621
(1R,3s,5S)-8-(chloromethyl)-3-(2-hydroxy-2,2-di(thiophen-2-yl)acetoxy)-8-methyl-8-azabicyclo[3.2.1]oct-6-en-8-ium iodide

TIOTROPIUM BROMIDE IMPURITY 22
CAS:3140-92-9
Formula: C4H2Br2S
241.93
RM-T201622
2,4-Dibromothiophene

TIOTROPIUM BROMIDE IMPURITY 23
CAS:3141-27-3
Formula: C4H2Br2S
241.93
RM-T201623
2,5-Dibromothiophene

TIOTROPIUM BROMIDE IMPURITY 24
CAS:3140-93-0
Formula: C4H2Br2S
241.93
RM-T201624
2,3-Dibromothiophene

Tiotropium Bromide Impurity 25
CAS:3141-26-2
Formula: C4H2Br2S
241.93
RM-T201625
3,4-DIBROMOTHIOPHENE

TIOTROPIUM BROMIDE IMPURITY 28
CAS:59516-66-4
Formula: C4H2O7
162.05
RM-T201628
2,2'-oxybis(2-oxoacetic acid)

TIOTROPIUM BROMIDE IMPURITY 29 (DIOXANE TETRAKETONE)
CAS:213967-57-8
Formula: C4O6
144.04
RM-T201629
1,4-Dioxane-2,3,5,6-tetrone

TIOTROPIUM BROMIDE IMPURITY 30 (SCOPOLINE)
CAS:487-27-4
Formula: C8H13NO2
155.19
RM-T201630
4-methylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-6-ol

Tiotropium Bromide Impurity 32
Formula: C13H16O3*2
220.27
RM-T201632
(R)-2-cyclopentyl-2-hydroxy-2-phenylacetic acid--(S)-2-cyclopentyl-2-hydroxy-2-phenylacetic acid (1/1)

Tiotropium Bromide Impurity 33
CAS:16202-15-6
Formula: C9H10O3
166.18
RM-T201633
(S)-3-hydroxy-2-phenylpropanoic acid

Tiotropium Bromide Impurity 34(Tropenol)
CAS:20513-09-1
Formula: C8H13NO
139.2
RM-T201636
(1R,3s,5S)-8-methyl-8-azabicyclo[3.2.1]oct-6-en-3-ol

Tiotropium Bromide Impurity 37
Formula: C9H14ClNO2
203.67
RM-T201637
(1R,2R,4S,5S,7s,9s)-9-(chloromethyl)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-9-ium-7-olate

Tiotropium Bromide Impurity 38
CAS:186691-13-4
Formula: C19H22BrNO4S2
472.41
RM-T201638
3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 7-[(2-hydroxy-2,2-di-2-thienylacetyl)oxy]-9,9-dimethyl-, bromide, hydrate (1:1:1), (1+¦,2+¦,4+¦,5+¦,7+¦)-

Tiotropium Bromide Impurity 39
Formula: C19H22BrNO4S2
472.41
RM-T201639
(2S,3aS,5R,6R)-6-(2-hydroxy-2,2-di(thiophen-2-yl)acetoxy)-4,4-dimethylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-4-ium bromide

Tiotropium Bromide Impurity 40
Formula: C17H21NO3
287.36
RM-T201640
(1R,3s,5S)-8-methyl-8-azabicyclo[3.2.1]oct-6-en-3-yl 3-hydroxy-2-phenylpropanoate

Tiotropium Bromide Impurity 41
Formula: C18H19NO4S2
377.47
RM-T201641
(1R,2R,4S,5S,7r)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl 2-hydroxy-2,2-di(thiophen-2-yl)acetate

Tiotropium Bromide Impurity 42
Formula: C18H19NO4S2
377.47
RM-T201642
(1R,2R,4S,5S,7s)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl 2-hydroxy-2-(thiophen-2-yl)-2-(thiophen-3-yl)acetate

Tiotropium Bromide Impurity 43
CAS:783273-13-2
Formula: C18H19NO4S2
377.47
RM-T201643
(1R,2S,4R,5S,7s)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl 2-hydroxy-2-(thiophen-2-yl)-2-(thiophen-3-yl)acetate

Tiotropium Bromide Impurity 44
Formula: C18H21NO4S2
379.49
RM-T201644
(1S,3R,5S,6R)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2,2-di(thiophen-2-yl)acetate

Tiotropium Bromide Impurity 45
Formula: C19H22NO4S2*I
392.51*126.91
RM-T201645
(1R,2R,4S,5S,7s)-7-(2-hydroxy-2-(thiophen-2-yl)-2-(thiophen-3-yl)acetoxy)-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-9-ium iodide

Tiotropium Bromide Impurity 46
Formula: C19H22NO4S2*Br
392.51*79.90
RM-T201646
(2S,3aS,5R,6R,6aR)-6-(2-hydroxy-2,2-di(thiophen-2-yl)acetoxy)-4,4-dimethylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-4-ium bromide

Tiotropium Bromide Impurity 47
Formula: C18H21NO3S2
363.49
RM-T201647
(1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2,2-di(thiophen-2-yl)acetate

Tiotropium Bromide Impurity 48
CAS:29461-90-3
Formula: C18H21NO3S2
363.49
RM-T201648
(1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2,2-di(thiophen-2-yl)acetate

Tiotropium Bromide Impurity 49
CAS:6006-81-1
Formula: C9H10O
134.18
RM-T201649
2-phenylprop-2-en-1-ol

Tiotropium Bromide Impurity 50
CAS:61616-97-5
Formula: C17H21NO3
287.36
RM-T201650
(1R,3s,5S)-8-methyl-8-azabicyclo[3.2.1]oct-6-en-3-yl (S)-3-hydroxy-2-phenylpropanoate

Tiotropium Bromide Impurity 52
CAS:4438-38-4
Formula: C8H11NO
137.18
RM-T201652
8-methyl-8-azabicyclo[3.2.1]oct-6-en-3-one

Tiotropium Bromide Impurity 53
Formula: C8H13NO2
155.2
RM-T201653
9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol

Tiotropium Bromide Impurity 54
CAS:498-45-3
Formula: C8H13NO2
155.2
RM-T201654
Scopine;(1R,2R,4S,5S,7s)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol

Tiotropium Bromide Impurity 55
CAS:2020375-99-7
Formula: C17H19NO3S2
349.46
RM-T201655
(S)-quinuclidin-3-yl 2-hydroxy-2,2-di(thiophen-2-yl)acetate

Tiotropium Bromide Impurity 56
Formula: C9H16NO2 Br
170.23 79.90
RM-T201656
(1R,2R,4S,5S,7s)-7-hydroxy-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-9-ium bromide

Tiotropium Bromide Impurity 57
Formula: C9H16NO2 Br
170.23 79.90
RM-T201657
(2R,3aS,5R)-6-hydroxy-4,4-dimethylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-4-ium bromide

Tiotropium Bromide Impurity 58
CAS:136431-94-2
Formula: C19H22NO4S2 Br
392.51 79.90
RM-T201658
7-(2-hydroxy-2-(thiophen-2-yl)-2-(thiophen-3-yl)acetoxy)-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-9-ium bromide

TIOTROPIUM EP IMPURITY A
CAS:4746-63-8
Formula: C10H8O3S2
240.3
RM-T201601
2-Hydroxy-2,2-dithiophen-2-ylacetic acid

TIOTROPIUM EP IMPURITY C
CAS:136310-95-7
Formula: C19H22NBrO3S2
456.42
RM-T201603
(1R,3s,5S)-3-[(2-Hydroxy-2,2-dithiophen-2-ylacetyl)oxy]-8,8-dimethyl-8-azoniabicyclo[3.2.1]oct-6-ene bromide; (1R,3s,5S)-3-(2-hydroxy-2,2-di(thiophen-2-yl)acetoxy)-8,8-dimethyl-8-azabicyclo[3.2.1]oct-6-en-8-ium bromide

TIOTROPIUM EP IMPURITY E
CAS:26447-85-8
Formula: C11H10O3S2
254.33
RM-T201605
Methyl 2-hydroxy-2,2-dithiophen-2-ylacetate

TIOTROPIUM EP IMPURITY F
CAS:704-38-1
Formula: C9H6OS2
194.27
RM-T201606
dithiophen-2-ylmethanone

TIOTROPIUM EP IMPURITY G
CAS:1508-46-9
Formula: C9H16NBrO2
250.13
RM-T201607
(1R,2R,4S,5S,7s)-7-Hydroxy-9,9-dimethyl-3-oxa-9-azoniatricyclo [3.3.1.02,4] nonane bromide

TIOTROPIUM EP IMPURITY I
CAS:136521-48-7
Formula: C19H22BrNO4S2
472.42
RM-T201609
(1R,2R,4S,5S,7r)-7-(2-hydroxy-2,2-di(thiophen-2-yl)acetoxy)-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-9-ium bromide

TIOTROPIUM EP IMPURITY J
Formula: C19H21Cl2NO3S2
446.41
RM-T201610
(1R,3s,5S,8s)-8-(chloromethyl)-3-(2-hydroxy-2,2-di(thiophen-2-yl)acetoxy)-8-methyl-8-azabicyclo[3.2.1]oct-6-en-8-ium chloride

TIOTROPIUM EP IMPURITY K
Formula: C19H19NO5S2
405.49
RM-T201611
(1R,2R,4S,5S,7s)-9-acetyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl 2-hydroxy-2,2-di(thiophen-2-yl)acetate

Tiotropium Impurity 34
CAS:736108-96-6
Formula: C18H19NO3S2
361.47
RM-T201634
(1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]oct-6-en-3-yl 2-hydroxy-2,2-di(thiophen-2-yl)acetate

Tiotropium Impurity 35
CAS:28748-67-6
Formula: C11H10O3S2
254.32
RM-T201635
methyl 2-hydroxy-2-(thiophen-2-yl)-2-(thiophen-3-yl)acetate

Tiotropium Impurity B
CAS:136310-64-0
Formula: C18H19NO4S2
377.48
RM-T201602
(1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl 2-hydroxy-2,2-dithiophen-2-ylacetate

Tiotropium Impurity D
CAS:136310-66-2
Formula: C18H19NO3S2
361.48
RM-T201604
(1R,3s,5S)-8-methyl-8-azabicyclo[3.2.1]oct-6-en-3-yl 2-hydroxy-2,2-di(thiophen-2-yl)acetate

TIOTROPIUM-D6 BROMIDE
CAS:1126775-44-7
Formula: C19H16D6NO4S2 Br
398.54 79.90
RM-T201651
(1R,2R,4S,5S,7s)-7-(2-hydroxy-2,2-di(thiophen-2-yl)acetoxy)-9,9-bis(methyl-d3)-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-9-ium bromide

TIPIRACIL HCL
CAS:183204-72-0
Formula: C9H12Cl2N4O2
279.12
RM-T041300
5-chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dione hydrochloride

TIPIRACIL IMPURITY 10
CAS:872-34-4
Formula: C4H8N2
84.12
RM-T041310
3,4-dihydro-2H-pyrrol-5-amine

Tipiracil Impurity 11
CAS:18592-13-7
Formula: C5H5ClN2O2
160.56
RM-T090514
6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione

Tipiracil Impurity 6
Formula: C5H3ClN2O3
174.54
RM-T041306
5-chloro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carbaldehyde

TIPIRACIL-13C-15N2 HCL
Formula: C813CH11ClN215N2O2 HCl
245.64 36.46
RM-T041307
Tipiracil-13C-15N2 HCl

Tipranavir Impurity 1
CAS:174484-41-4
Formula: C31H33F3N2O5S
602.67
RM-T100002
N-(3-((R)-1-((R)-4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)propyl)phenyl)-5-(trifluoromethyl)pyridine-2-sulfonamide

TIROFIBAN HCL
CAS:142373-60-2
Formula: C22H37ClN2O5S
477.06
RM-T180600
(S)-2-(Butylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid hydrochloride

TIROFIBAN IMPURITY 10
CAS:464175-13-1(free base)
Formula: C9H19Cl2N
212.16
RM-T180636
4-(4-chlorobutyl)piperidine hydrochloride

Tirofiban Impurity 101
Formula: C22H30N2O5S
434.55
RM-T180701
2-(butylsulfonamido)-3-(4-(4-(pyridin-4-yl)butoxy)phenyl)propanoic acid

Tirofiban Impurity 102
Formula: C6H14O3S
166.24
RM-T180702
tert-butyl ethanesulfonate

Tirofiban Impurity 103
CAS:14245-63-7
Formula: C6H14O3S
166.24
RM-T180703
butyl ethanesulfonate

Tirofiban Impurity 104
Formula: C13H20O4S
272.36
RM-T180704
3-hydroxy-2,3-dimethylbutan-2-yl 4-methylbenzenesulfonate

Tirofiban Impurity 105
Formula: C8H18O4S
210.29
RM-T180705
3-hydroxy-2,3-dimethylbutan-2-yl ethanesulfonate

Tirofiban Impurity 106
CAS:2244604-49-5
Formula: C21H22ClN3
351.88
RM-T180706
4,4',4''-(6-chlorohexane-1,2,3-triyl)tripyridine

Tirofiban Impurity 107
CAS:2374-66-5
Formula: C8H18O3S
194.29
RM-T180707
butyl butane-1-sulfonate

Tirofiban Impurity 108
Formula: C12H17NO5S
287.33
RM-T180708
(propylsulfonyl)-D-tyrosine

TIROFIBAN IMPURITY 11
CAS:2374-69-8
Formula: C5H12O3S
152.21
RM-T180637
methyl butane-1-sulfonate

Tirofiban Impurity 110
Formula: C21H28N2O5S
420.52
RM-T180710
(R)-2-(propylsulfonamido)-3-(4-(4-(pyridin-4-yl)butoxy)phenyl)propanoic acid

Tirofiban Impurity 111
CAS:155727-68-7
Formula: C24H40N2O5S
468.65
RM-T180711
ethyl (S)-2-(butylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoate

Tirofiban Impurity 112
CAS:721444-72-0
Formula: C10H13NO5S
259.28
RM-T180712
(methylsulfonyl)-L-tyrosine

Tirofiban Impurity 113
CAS:1103328-61-5
Formula: C11H15NO5S
273.3
RM-T180713
(ethylsulfonyl)-L-tyrosine

Tirofiban Impurity 114
Formula: C18H20N2O5
344.37
RM-T180714
(S)-3-(4-((L-tyrosyl)oxy)phenyl)-2-aminopropanoic acid

Tirofiban Impurity 115
Formula: C31H53N3O5S
579.84
RM-T180715
4-(piperidin-4-yl)butyl (S)-2-(butylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoate

Tirofiban Impurity 116
CAS:1332692-49-5
Formula: C23H38N2O5S
454.63
RM-T180716
(S)-2-(pentylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid

Tirofiban Impurity 117
Formula: C14H21NO5S
315.38
RM-T180717
(pentylsulfonyl)-L-tyrosine

Tirofiban Impurity 118
Formula: C31H41N3O5S
567.75
RM-T180718
4-(pyridin-4-yl)butyl (S)-2-(butylsulfonamido)-3-(4-(4-(pyridin-4-yl)butoxy)phenyl)propanoate

TIROFIBAN IMPURITY 13
CAS:2714335-86-9
Formula: C31H53N3O5S
579.83
RM-T180639
(S)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)-2-(N-(4-(piperidin-4-yl)butyl)butylsulfonamido)propanoic acid

TIROFIBAN IMPURITY 2
CAS:2713130-63-1
Formula: C22H35ClN2O5S
475.04
RM-T180628
(S)-2-(butylsulfonamido)-3-(3-chloro-4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid

TIROFIBAN IMPURITY 3
Formula: C20H24N2O4
356.42
RM-T180629
(S)-2-acetamido-3-(4-(4-(pyridin-4-yl)butoxy)phenyl)propanoic acid

TIROFIBAN IMPURITY 4
Formula: C9H19NO2
173.25
RM-T180630
4-(4-hydroxybutyl)piperidin-1-ol

TIROFIBAN IMPURITY 40
CAS:91284-46-7
Formula: C7H16O3S
180.27
RM-T180640
isopropyl butane-1-sulfonate

TIROFIBAN IMPURITY 41
Formula: C16H23NO2
261.36
RM-T180641
4-(4-(piperidin-4-yl)butoxy)benzaldehyde

TIROFIBAN IMPURITY 42
Formula: C32H43N3O5S
581.77
RM-T180642
(S)-methyl 3-(4-(4-(pyridin-4-yl)butoxy)phenyl)-2-(N-(4-(pyridin-4-yl)butyl)butylsulfonamido)propanoate

TIROFIBAN IMPURITY 43
Formula: C24H38N2O6S
482.63
RM-T180643
(R)-3-(4-(4-(1-acetylpiperidin-4-yl)butoxy)phenyl)-2-(butylsulfonamido)propanoic acid

TIROFIBAN IMPURITY 44
Formula: C15H16N2
224.3
RM-T180644
(E)-4,4'-(pent-1-ene-1,5-diyl)dipyridine

TIROFIBAN IMPURITY 45
CAS:2250244-28-9
Formula: C13H19NO5S
301.36
RM-T180645
(S)-2-amino-3-(4-((butylsulfonyl)oxy)phenyl)propanoic acid

TIROFIBAN IMPURITY 46
Formula: C13H27NO3S HCl
277.42 36.46
RM-T180646
4-(piperidin-4-yl)butyl butane-1-sulfonate hydrochloride

TIROFIBAN IMPURITY 47
CAS:1346918-32-8
Formula: C13H19NO5S
301.36
RM-T180647
(R)-2-(butylsulfonamido)-3-(4-hydroxyphenyl)propanoic acid

TIROFIBAN IMPURITY 48
CAS:1838627-40-9
Formula: C22H36N2O6S
456.6
RM-T180648
(2S)-2-(butylsulfonamido)-3-hydroxy-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid

TIROFIBAN IMPURITY 49
Formula: C40H64N4O6S
729.02
RM-T180649
(S)-3-(4-(4-(piperidin-4-yl)butoxy)-3-(4-(pyridin-4-yl)butoxy)phenyl)-2-(N-(4-(piperidin-4-yl)butyl)butylsulfonamido)propanoic acid

TIROFIBAN IMPURITY 5
CAS:5264-15-3
Formula: C9H13NO
151.21
RM-T180631
4-(Pyridin-4-yl)butan-1-ol

TIROFIBAN IMPURITY 50
Formula: C31H53N3O6S 2HCl
595.83 72.92
RM-T180650
(S)-2-(N-(4-(piperidin-4-yl)butoxy)butylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid dihydrochloride

TIROFIBAN IMPURITY 51
Formula: C18H29NO7S2
435.56
RM-T180651
(S)-methyl 2-(butylsulfonamido)-3-(4-((butylsulfonyl)oxy)phenyl)propanoate

TIROFIBAN IMPURITY 52
CAS:4916-57-8
Formula: C12H12N2
184.24
RM-T180652
1,2-di(pyridin-4-yl)ethane

TIROFIBAN IMPURITY 53
Formula: C13H19NO5S
301.36
RM-T180653
2-(butylsulfonamido)-3-(4-hydroxyphenyl)propanoic acid

TIROFIBAN IMPURITY 54
Formula: C24H38N2O6S
482.63
RM-T180654
(S)-3-(4-(4-(1-acetylpiperidin-4-yl)butoxy)phenyl)-2-(butylsulfonamido)propanoic acid

Tirofiban Impurity 55
Formula: C12H17NO5S
287.33
RM-T180655
(R)-3-(4-hydroxyphenyl)-2-(propylsulfonamido)propanoic acid

TIROFIBAN IMPURITY 56
Formula: C11H15NO5S
273.31
RM-T180656
(R)-2-(ethylsulfonamido)-3-(4-hydroxyphenyl)propanoic acid

TIROFIBAN IMPURITY 57
Formula: C10H13NO5S
259.28
RM-T180657
(R)-3-(4-hydroxyphenyl)-2-(methylsulfonamido)propanoic acid

TIROFIBAN IMPURITY 58
CAS:6304-31-0
Formula: C10H15N
149.23
RM-T180658
2-butyl-4-methylpyridine

TIROFIBAN IMPURITY 59
CAS:1134-35-6
Formula: C12H12N2
184.24
RM-T180659
4,4'-Dimethyl-2,2'-bipyridine

TIROFIBAN IMPURITY 6
Formula: C13H21NO3S
271.38
RM-T180632
4-(pyridin-4-yl)butyl butane-1-sulfonate

TIROFIBAN IMPURITY 60
Formula: C20H26N2O5S
406.5
RM-T180660
(R)-2-(ethylsulfonamido)-3-(4-(4-(pyridin-4-yl)butoxy)phenyl)propanoic acid

TIROFIBAN IMPURITY 61
Formula: C19H24N2O5S
392.47
RM-T180661
(R)-2-(methylsulfonamido)-3-(4-(4-(pyridin-4-yl)butoxy)phenyl)propanoic acid

Tirofiban Impurity 62
Formula: C22H30N2O5S
434.55
RM-T180662
(S)-3-(4-((butylsulfonyl)oxy)phenyl)-2-((4-(pyridin-4-yl)butyl)amino)propanoic acid

TIROFIBAN IMPURITY 63
Formula: C31H41N3O5S
567.74
RM-T180663
(S)-2-(bis(4-(pyridin-4-yl)butyl)amino)-3-(4-((butylsulfonyl)oxy)phenyl)propanoic acid

TIROFIBAN IMPURITY 64
Formula: C21H34N2O5S
426.57
RM-T180664
(R)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)-2-(propylsulfonamido)propanoic acid

TIROFIBAN IMPURITY 65
Formula: C20H32N2O5S
412.54
RM-T180665
(R)-2-(ethylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid

TIROFIBAN IMPURITY 66
Formula: C19H30N2O5S
398.52
RM-T180666
(R)-2-(methylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid

Tirofiban Impurity 67
Formula: C22H36N2O5S
440.6
RM-T180667
(S)-3-(4-((butylsulfonyl)oxy)phenyl)-2-((4-(piperidin-4-yl)butyl)amino)propanoic acid

TIROFIBAN IMPURITY 68
Formula: C31H53N3O5S
579.83
RM-T180668
(S)-2-(bis(4-(piperidin-4-yl)butyl)amino)-3-(4-((butylsulfonyl)oxy)phenyl)propanoic acid

TIROFIBAN IMPURITY 69
CAS:25561-30-2
Formula: C8H18F3NOSi2
257.4
RM-T180669
trimethylsilyl 2,2,2-trifluoro-N-(trimethylsilyl)acetimidate

TIROFIBAN IMPURITY 7
Formula: C21H35ClN2O5S
463.03
RM-T180633
3-(4-(4-(piperidin-4-yl)butoxy)phenyl)-2-(propylsulfonamido)propanoic acid hydrochloride

TIROFIBAN IMPURITY 70
CAS:109315-44-8
Formula: C9H12BrN
214.1
RM-T180670
4-(4-bromobutyl)pyridine

TIROFIBAN IMPURITY 71
Formula: C22H35ClN2O5S
475.04
RM-T180671
2-(butylsulfonamido)-3-(2-chloro-4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid

TIROFIBAN IMPURITY 72
CAS:594-44-5
Formula: C2H5ClO2S
128.58
RM-T180672
Ethanesulfonyl chloride

TIROFIBAN IMPURITY 73
CAS:10147-36-1
Formula: C3H7ClO2S
142.6
RM-T180673
propane-1-sulfonyl chloride

TIROFIBAN IMPURITY 74
CAS:1103300-75-9
Formula: C12H17NO5S
287.33
RM-T180674
(S)-3-(4-hydroxyphenyl)-2-(propylsulfonamido)propanoic acid

Tirofiban Impurity 75
Formula: C21H28N2O5S
420.52
RM-T180675
(S)-2-(propylsulfonamido)-3-(4-(4-(pyridin-4-yl)butoxy)phenyl)propanoic acid

Tirofiban Impurity 76
Formula: C20H26N2O5S
406.5
RM-T180676
(S)-2-(ethylsulfonamido)-3-(4-(4-(pyridin-4-yl)butoxy)phenyl)propanoic acid

Tirofiban Impurity 77
Formula: C19H24N2O5S
392.47
RM-T180677
(S)-2-(methylsulfonamido)-3-(4-(4-(pyridin-4-yl)butoxy)phenyl)propanoic acid

Tirofiban Impurity 78
CAS:158808-85-6
Formula: C21H34N2O5S
426.57
RM-T180678
(S)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)-2-(propylsulfonamido)propanoic acid

TIROFIBAN IMPURITY 79
Formula: C20H32N2O5S
412.54
RM-T180679
(S)-2-(ethylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid

Tirofiban Impurity 80
Formula: C19H30N2O5S
398.52
RM-T180680
(S)-2-(methylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid

TIROFIBAN IMPURITY 81
Formula: C23H38N2O5S
454.62
RM-T180681
(S)-2-(butylsulfonamido)-3-(4-(4-(1-methylpiperidin-4-yl)butoxy)phenyl)propanoic acid

TIROFIBAN IMPURITY 82
Formula: C17H28N2O
276.42
RM-T180682
2-(4-(4-(piperidin-4-yl)butoxy)phenyl)ethanamine

TIROFIBAN IMPURITY 83
CAS:85691-54-9(free base)
Formula: C10H13NO2 HCl
179.22 36.46
RM-T180683
methyl 4-(pyridin-4-yl)butanoate hydrochloride

TIROFIBAN IMPURITY 84
Formula: C22H34N2O6S
454.58
RM-T180684
N-(7-(4-(1-hydroxypiperidin-4-yl)butoxy)-2-oxochroman-3-yl)butane-1-sulfonamide

Tirofiban Impurity 85
Formula: C12H17Cl2N
246.18
RM-T180685
4-(1,7-dichloroheptan-4-yl)pyridine

Tirofiban Impurity 86
Formula: C17H18N2O4
314.34
RM-T180686
2,2-bis(2-(pyridin-4-yl)ethyl)malonic acid

Tirofiban Impurity 87
Formula: C16H18N2O2
270.33
RM-T180687
4-(pyridin-4-yl)-2-(2-(pyridin-4-yl)ethyl)butanoic acid

Tirofiban Impurity 88
Formula: C9H14BN
147.03
RM-T180688
4-(4-borylbutyl)pyridine

Tirofiban Impurity 89
Formula: C9H13NO2
167.21
RM-T180689
4-(4-hydroxybutyl)pyridine 1-oxide

TIROFIBAN IMPURITY 9
CAS:25382-33-6(free base)
Formula: C15H20Cl2N2
299.24
RM-T180635
1,5-di(pyridin-4-yl)pentane dihydrochloride

Tirofiban Impurity 90
Formula: C16H20N2O
256.34
RM-T180690
4-(pyridin-4-yl)-2-(2-(pyridin-4-yl)ethyl)butan-1-ol

Tirofiban Impurity 91
Formula: C18H24N2O
284.4
RM-T180691
4,4'-(oxybis(butane-4,1-diyl))dipyridine

Tirofiban Impurity 92
Formula: C17H27NO7S2
421.53
RM-T180692
(S)-2-(N-(butylsulfonyl)butylsulfonamido)-3-(4-hydroxyphenyl)propanoic acid

Tirofiban Impurity 93
Formula: C27H38N2O10S2
614.73
RM-T180693
(2S,2'S)-3,3'-((methylenebis(oxy))bis(4,1-phenylene))bis(2-(butylsulfonamido)propanoic acid)

TIROFIBAN IMPURITY 94
CAS:151414-73-2
Formula: C23H32N2O5S
448.58
RM-T180694
(S)-methyl 2-(butylsulfonamido)-3-(4-(4-(pyridin-4-yl)butoxy)phenyl)propanoate

Tirofiban Impurity 95
Formula: C30H39N3O5S
553.71
RM-T180695
(S)-3-(pyridin-4-yl)propyl 2-(butylsulfonamido)-3-(4-(4-(pyridin-4-yl)butoxy)phenyl)propanoate

Tirofiban Impurity 96
Formula: C23H38N2O5S
454.62
RM-T180696
(S)-methyl 2-(butylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoate

Tirofiban Impurity 98
Formula: C18H24Cl2N2
339.3
RM-T180698
4-(4-chlorobutyl)-1-(4-(pyridin-4-yl)butyl)pyridin-1-ium chloride

Tirofiban Impurity 99; Tirofiban Impurity W
Formula: C22H42N2O5S
446.65
RM-T180699
(S)-2-(butylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)cyclohexyl)propanoic acid

TIROFIBAN IMPURITY A
CAS:149490-60-8
Formula: C13H19NO5S
301.36
RM-T180601
(butylsulfonyl)-L-tyrosine

TIROFIBAN IMPURITY B
CAS:149463-65-0
Formula: C9H12ClN. HCl
169.66 36.46
RM-T180602
4-(4-Chlorobutyl)pyridine hydrochloride

TIROFIBAN IMPURITY C
Formula: C31H43Cl2N3O5S
640.66
RM-T180603
3-(4-(4-(pyridin-4-yl)butoxy)phenyl)-2-(N-(4-(pyridin-4-yl)butyl)butylsulfonamido)propanoic acid dihydrochloride

Tirofiban impurity D
CAS:149490-61-9
Formula: C22H30N2O5S
434.55
RM-T180604
(S)-2-(Butylsulfonamido)-3-(4-(4-(pyridin-4-yl)butoxy)phenyl)propanoic acid

Tirofiban Impurity E
Formula: C9H12ClNO
185.65
RM-T180605
4-(4-chlorobutyl)pyridine 1-oxide

Tirofiban Impurity F
Formula: C22H30N2O6S
450.55
RM-T180606
(S)-4-(4-(4-(2-(butylsulfonamido)-2-carboxyethyl)phenoxy)butyl)pyridine 1-oxide

Tirofiban impurity G
Formula: C22H35N2NaO6S
478.58
RM-T180607
sodium (S)-2-(butylsulfonamido)-3-(4-(4-(1-hydroxypiperidin-4-yl)butoxy)phenyl)propanoate

Tirofiban Impurity I
CAS:2250244-31-4
Formula: C17H27NO7S2
421.53
RM-T180609
(S)-2-(butylsulfonamido)-3-(4-((butylsulfonyl)oxy)phenyl)propanoic acid

Tirofiban Impurity J
Formula: C31H49Cl2N3O5S
646.71
RM-T180610
(S)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)-2-(N-(4-(pyridin-4-yl)butyl)butylsulfonamido)propanoic acid dihydrochloride

Tirofiban Impurity L
Formula: C18H22N2O3
314.38
RM-T180612
(S)-2-amino-3-(4-(4-(pyridin-4-yl)butoxy)phenyl)propanoic acid

TIROFIBAN IMPURITY M
CAS:158808-75-4
Formula: C18H28N2O3
320.43
RM-T180613
(S)-2-amino-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid

Tirofiban Impurity N
Formula: C18H22N2O3
314.38
RM-T180614
(S)-3-(4-hydroxyphenyl)-2-((4-(pyridin-4-yl)butyl)amino)propanoic acid

Tirofiban Impurity O
Formula: C18H28N2O3
320.43
RM-T180615
(S)-3-(4-hydroxyphenyl)-2-((4-(piperidin-4-yl)butyl)amino)propanoic acid

Tirofiban Impurity P
Formula: C27H33N3O3
447.57
RM-T180616
(S)-3-(4-(4-(pyridin-4-yl)butoxy)phenyl)-2-((4-(pyridin-4-yl)butyl)amino)propanoic acid

Tirofiban Impurity Q
Formula: C27H47Cl2N3O3
532.59
RM-T180617
(S)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)-2-((4-(piperidin-4-yl)butyl)amino)propanoic acid dihydrochloride

Tirofiban Impurity R
Formula: C36H44N4O3
580.76
RM-T180618
(S)-2-(bis(4-(pyridin-4-yl)butyl)amino)-3-(4-(4-(pyridin-4-yl)butoxy)phenyl)propanoic acid

Tirofiban Impurity S
Formula: C36H62N4O3
598.9
RM-T180619
(S)-2-(bis(4-(piperidin-4-yl)butyl)amino)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid

Tirofiban Impurity T
Formula: C22H30N2O5S
434.55
RM-T180620
(R)-2-(butylsulfonamido)-3-(4-(4-(pyridin-4-yl)butoxy)phenyl)propanoic acid

TIROFIBAN IMPURITY U
CAS:2374-68-7
Formula: C6H14O3S
166.24
RM-T180621
ethyl butane-1-sulfonate

Tirofiban Impurity V
Formula: C31H41N3O5S
567.74
RM-T180622
(S)-3-(4-(4-(pyridin-4-yl)butoxy)phenyl)-2-(N-(4-(pyridin-4-yl)butyl)butylsulfonamido)propanoic acid

Tirofiban Impurity X
Formula: C22H35ClN2O5S HCl
475.04 36.46
RM-T180624
(S)-2-(butylsulfonamido)-3-(2-chloro-4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid hydrochloride

Tirofiban Impurity Y
Formula: C22H37ClN2O5S
477.06
RM-T180625
2-(butylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid hydrochloride

TIROFIBAN IMPURITY Z
CAS:102878-73-9
Formula: C9H11NO2
165.19
RM-T180626
4-(pyridin-4-yl)butanoic acid

TIRZEPATIDE
CAS:2023788-19-2
Formula: C225H348N48O68
4813.53
RM-T466000
TIRZEPATIDE

Tirzepatide Impurity 1
Formula: C109H176N14O27
2114.68
RM-T466001
(2-((2S,3S)-2-((S)-3-(tert-butoxy)-2-((S)-2-((S)-4-(tert-butoxy)-2-((S)-3-(tert-butoxy)-2-((2S,3R)-3-(tert-butoxy)-2-((S)-2-((2S,3R)-3-(tert-butoxy)-2-(2-((S)-5-(tert-butoxy)-2-(2-((S)-3-(4-(tert-butoxy)phenyl)-2-((tert-butoxycarbonyl)amino

Tirzepatide Impurity 10
Formula: C225H347N47O69
4814.51
RM-T466010
Tirzepatide Impurity 10

Tirzepatide Impurity 11
Formula: C225H347N47O69
4814.51
RM-T466011
Tirzepatide Impurity 11

Tirzepatide Impurity 12
CAS:2915356-76-0
Formula: C66H105N5O16
1224.59
RM-T466012
Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH; (25S,52S)-52-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-25-(tert-butoxycarbonyl)-2,2-dimethyl-4,23,28,37,46-pentaoxo-3,32,35,41,44-pentaoxa-24,29,38,47-tetraazatripentacontan-53-oic acid

Tirzepatide Impurity 13
Formula: C61H95N5O16
1154.45
RM-T466013
(22S,49R)-49-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-22-(tert-butoxycarbonyl)-4,20,25,34,43-pentaoxo-3,29,32,38,41-pentaoxa-21,26,35,44-tetraazapentacontan-50-oic acid

Tirzepatide Impurity 14
Formula: C61H95N5O16
1154.45
RM-T466014
(22S,49S)-49-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-22-(ethoxycarbonyl)-2,2-dimethyl-4,20,25,34,43-pentaoxo-3,29,32,38,41-pentaoxa-21,26,35,44-tetraazapentacontan-50-oic acid

Tirzepatide Impurity 15
Formula: C65H103N5O16
1210.56
RM-T466015
(24R,51S)-51-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-24-(tert-butoxycarbonyl)-2,2-dimethyl-4,22,27,36,45-pentaoxo-3,31,34,40,43-pentaoxa-23,28,37,46-tetraazadopentacontan-52-oic acid

Tirzepatide Impurity 16
Formula: C72H116N6O19
1369.74
RM-T466016
(25S,61S)-61-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-25-(tert-butoxycarbonyl)-2,2-dimethyl-4,23,28,37,46,55-hexaoxo-3,32,35,41,44,50,53-heptaoxa-24,29,38,47,56-pentaazadohexacontan-62-oic acid

Tirzepatide Impurity 17
Formula: C60H94N4O13
1079.43
RM-T466017
(25R,43S)-43-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-25-(tert-butoxycarbonyl)-2,2-dimethyl-4,23,28,37-tetraoxo-3,32,35-trioxa-24,29,38-triazatetratetracontan-44-oic acid

Tirzepatide Impurity 18
Formula: C87H127N7O19
1575
RM-T466018
(25S,52S,59S)-52,59-bis((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-25-(tert-butoxycarbonyl)-2,2-dimethyl-4,23,28,37,46,53-hexaoxo-3,32,35,41,44-pentaoxa-24,29,38,47,54-pentaazahexacontan-60-oic acid

Tirzepatide Impurity 19
Formula: C67H107N5O16
1238.61
RM-T466019
32,52-di-tert-butyl 5-methyl (5S)-1-(9H-fluoren-9-yl)-3,11,20,29,34-pentaoxo-2,13,16,22,25-pentaoxa-4,10,19,28,33-pentaazadopentacontane-5,32,52-tricarboxylate

Tirzepatide Impurity 2
Formula: C121H181N13O27
2249.84
RM-T466002
((25S,52S)-52-((S)-2-((S)-2-((2S,3S)-2-((S)-2-((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(tert-butoxy)-4-oxobutanamido)-6-((tert-butoxycarbonyl)amino)hexanamido)-3-methylpentanamido)propanamido)-5-oxo-5-(tritylamino)pentanamido)-2

Tirzepatide Impurity 20
Formula: C70H113N5O16
1280.69
RM-T466020
tri-tert-butyl (5S)-1-(9H-fluoren-9-yl)-3,11,20,29,34-pentaoxo-2,13,16,22,25-pentaoxa-4,10,19,28,33-pentaazadopentacontane-5,32,52-tricarboxylate

Tirzepatide Impurity 21
Formula: C66H105N5O16
1224.59
RM-T466021
(25S,52R)-52-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-25-(tert-butoxycarbonyl)-2,2-dimethyl-4,23,28,37,46-pentaoxo-3,32,35,41,44-pentaoxa-24,29,38,47-tetraazatripentacontan-53-oic acid

Tirzepatide Impurity 22
Formula: C66H105N5O16
1224.59
RM-T466022
(25R,52S)-52-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-25-(tert-butoxycarbonyl)-2,2-dimethyl-4,23,28,37,46-pentaoxo-3,32,35,41,44-pentaoxa-24,29,38,47-tetraazatripentacontan-53-oic acid

Tirzepatide Impurity 23
Formula: C66H105N5O16
1224.59
RM-T466023
(25R,52R)-52-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-25-(tert-butoxycarbonyl)-2,2-dimethyl-4,23,28,37,46-pentaoxo-3,32,35,41,44-pentaoxa-24,29,38,47-tetraazatripentacontan-53-oic acid

Tirzepatide Impurity 24
Formula: C69H110N6O17
1295.66
RM-T466024
56-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-25-(tert-butoxycarbonyl)-2,2-dimethyl-4,23,28,32,41,50-hexaoxo-3,36,39,45,48-pentaoxa-24,29,33,42,51-pentaazaheptapentacontan-57-oic acid

Tirzepatide Impurity 25
Formula: C11H15NO6
257.24
RM-T466025
tert-Butyl (2,5-Dioxopyrrolidin-1-yl) Malonate

Tirzepatide Impurity 26
Formula: C16H27NO7
345.39
RM-T466026
(S)-5-(tert-butoxy)-4-(3-(tert-butoxy)-3-oxopropanamido)-5-oxopentanoic acid

Tirzepatide Impurity 27
Formula: C20H30N2O9
442.47
RM-T466027
1-(tert-butyl) 5-(2,5-dioxopyrrolidin-1-yl) (3-(tert-butoxy)-3-oxopropanoyl)-L-glutamate

Tirzepatide Impurity 28
Formula: C25H43N3O13
593.63
RM-T466028
(S)-7-(tert-butoxycarbonyl)-3,5,10,19-tetraoxo-2,14,17,23,26-pentaoxa-6,11,20-triazaoctacosan-28-oic acid

Tirzepatide Impurity 3
Formula: C86H100N10O14
1497.8
RM-T466003
Na-(N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-L-phenylalanyl-L-valyl-N5-trityl-L-glutaminyl)-1-(tert-butoxycarbonyl)-L-tryptophyl-L-leucyl-L-isoleucyl-L-alanylglycine

Tirzepatide Impurity 4
Formula: C48H81N11O13
1020.24
RM-T466004
(S)-N-((S)-1-amino-3-(tert-butoxy)-1-oxopropan-2-yl)-1-(O-(tert-butyl)-N-(O-(tert-butyl)-N-glycyl-L-prolyl-L-seryl)-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl)pyrrolidine-2-carboxamide

Tirzepatide Impurity 5
Formula: C225H348N48O68
4813.53
RM-T466005
Tirzepatide Impurity 5

Tirzepatide Impurity 6
Formula: C225H348N48O68
4813.53
RM-T466006
Tirzepatide Impurity 6

Tirzepatide Impurity 7
Formula: C224H346N48O68
4799.5
RM-T466007
Tirzepatide Impurity 7

Tirzepatide Impurity 8
Formula: C225H348N48O68
4813.53
RM-T466008
Tirzepatide Impurity 8

Tirzepatide Impurity 9
Formula: C225H347N47O69
4814.51
RM-T466009
Tirzepatide Impurity 9

TIXOCORTOL PIVALATE
CAS:55560-96-8
Formula: C26H38O5S
462.64
RM-T092401
S-(2-((8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl) 2,2-dimethylpropanethioate

TIZANIDINE
CAS:51322-75-9
Formula: C9H8ClN5S
253.71
RM-T092600
5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)benzo[c][1,2,5]thiadiazol-4-amine

TIZANIDINE EP IMPURITY A
CAS:51322-69-1
Formula: C9H9N5S
219.27
RM-T092601
N-(4,5-dihydro-1H-imidazol-2-yl)benzo[c][1,2,5]thiadiazol-4-amine

TIZANIDINE EP IMPURITY B
CAS:51323-05-8
Formula: C7H5ClN4S2
244.72
RM-T092602
1-(5-chlorobenzo[c][1,2,5]thiadiazol-4-yl)thiourea

TIZANIDINE EP IMPURITY C
CAS:1147548-83-1
Formula: C16H14Cl2N10S2
481.39
RM-T092603
1,1'-(ethane-1,2-diyl)bis(3-(5-chlorobenzo[c][1,2,5]thiadiazol-4-yl)guanidine)

TIZANIDINE EP IMPURITY D
CAS:560120-68-5
Formula: C8H7ClN4S2
258.75
RM-T092604
methyl (5-chlorobenzo[c][1,2,5]thiadiazol-4-yl)carbamimidothioate

TIZANIDINE EP IMPURITY E
CAS:30536-19-7
Formula: C6H4ClN3S
185.63
RM-T092605
5-chlorobenzo[c][1,2,5]thiadiazol-4-amine

TIZANIDINE EP IMPURITY F
CAS:1147548-85-3
Formula: C16H11Cl2N9S2
464.35
RM-T092606
1,3-bis(5-chlorobenzo[c][1,2,5]thiadiazol-4-yl)-1-(4,5-dihydro-1H-imidazol-2-yl)guanidine

TIZANIDINE EP IMPURITY G
CAS:51322-80-6
Formula: C7H3ClN4S
210.64
RM-T092607
N-(5-chlorobenzo[c][1,2,5]thiadiazol-4-yl)cyanamide

TIZANIDINE IMPURITY 20
CAS:173532-15-5
Formula: C11H10ClN5OS
295.75
RM-T092620
1-(2-((5-chlorobenzo[c][1,2,5]thiadiazol-4-yl)amino)-4,5-dihydro-1H-imidazol-1-yl)ethanone

Tizanidine Impurity 21
CAS:5391-52-6
Formula: C5H8N2OS
144.19
RM-T092621
1-(2-thioxoimidazolidin-1-yl)ethan-1-one

Tizanidine Impurity 23
CAS:2207-32-1
Formula: C6H3ClN2S
170.61
RM-T092623
5-chlorobenzo[c][1,2,5]thiadiazole

Tizanidine Impurity 24
CAS:2274-89-7
Formula: C6H2ClN3O2S
215.61
RM-T092624
5-chloro-4-nitrobenzo[c][1,2,5]thiadiazole

Tizanidine Impurity 25
CAS:100191-31-9
Formula: C6H4ClN3S
185.63
RM-T092625
6-chlorobenzo[c][1,2,5]thiadiazol-5-amine

Tizanidine Impurity 26
Formula: C6H4ClN3S
185.63
RM-T092626
6-chlorobenzo[c][1,2,5]thiadiazol-4-amine

Tizanidine Impurity 27
Formula: C9H8ClN5S
253.71
RM-T092627
6-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)benzo[c][1,2,5]thiadiazol-5-amine

Tizanidine Impurity 28
Formula: C11H10ClN5OS
295.75
RM-T092628
(E)-1-(1-((5-chlorobenzo[c][1,2,5]thiadiazol-4-yl)imino)ethyl)imidazolidin-2-one

Tizanidine Impurity 29
Formula: C11H11N5OS
261.3
RM-T092629
1-(2-(benzo[c][1,2,5]thiadiazol-4-ylamino)-4,5-dihydro-1H-imidazol-1-yl)ethan-1-one

Tizanidine Impurity 30
Formula: C13H12ClN5O2S
337.78
RM-T092630
(E)-1-acetyl-3-(1-((5-chlorobenzo[c][1,2,5]thiadiazol-4-yl)imino)ethyl)imidazolidin-2-one

Tizanidine Impurity 31
Formula: C11H10ClN5OS
295.75
RM-T092631
1-(2-((6-chlorobenzo[c][1,2,5]thiadiazol-5-yl)amino)-4,5-dihydro-1H-imidazol-1-yl)ethan-1-one

Tizanidine Impurity 32
Formula: C11H11ClN4O3
282.68
RM-T092632
1-(2-((4-chloro-2-nitrophenyl)amino)-4,5-dihydro-1H-imidazol-1-yl)ethan-1-one

Tizanidine Impurity 33
CAS:34658-84-9
Formula: C9H11ClN4
210.67
RM-T092633
4-chloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,2-diamine

Tizanidine Impurity 34
CAS:65959-12-8
Formula: C9H11ClN4
210.67
RM-T092634
5-chloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,2-diamine

Tizanidine Impurity 35
Formula: C9H9ClN4O2
240.65
RM-T092635
N-(4-chloro-2-nitrophenyl)-4,5-dihydro-1H-imidazol-2-amine

Tizanidine Impurity 36
Formula: C16H12ClN5OS
357.82
RM-T092636
(2-((5-chlorobenzo[c][1,2,5]thiadiazol-4-yl)amino)-4,5-dihydro-1H-imidazol-1-yl)(phenyl)methanone

Tizanidine Impurity 37
Formula: C17H14N2O3
294.31
RM-T092637
(2-oxoimidazolidine-1,3-diyl)bis(phenylmethanone)

Tizanidine Impurity 38
CAS:767-64-6
Formula: C6H5N3S
151.19
RM-T092638
Benzo[c][1,2,5]thiadiazol-4-amine

Tizanidine Impurity 39
CAS:2207-33-2
Formula: C6H2ClN3O2S
215.61
RM-T092639
5-Chloro-6-nitrobenzo[c][1,2,5]thiadiazole

Tizanidine Impurity 40
CAS:5391-40-2
Formula: C7H10N2O3
170.17
RM-T092640
1,1'-(2-oxoimidazolidine-1,3-diyl)bis(ethan-1-one)

Tizanidine Impurity 41
Formula: C6HCl2N3O2S
250.05
RM-T092641
5,6-dichloro-4-nitrobenzo[c][1,2,5]thiadiazole

Tizanidine Impurity 42
Formula: C6H2ClN3O2S
215.61
RM-T092642
6-chloro-4-nitrobenzo[c][1,2,5]thiadiazole

Tizanidine Impurity 43
Formula: C9H7Cl2N5S
288.15
RM-T092643
5,6-dichloro-N-(4,5-dihydro-1H-imidazol-2-yl)benzo[c][1,2,5]thiadiazol-4-amine

Tizanidine Impurity 44
Formula: C9H8ClN5S
253.71
RM-T092644
6-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)benzo[c][1,2,5]thiadiazol-4-amine

Tizanidine Impurity 45
Formula: C9H7ClN6OS
282.71
RM-T092645
N-(5-chlorobenzo[c][1,2,5]thiadiazol-4-yl)-N-(4,5-dihydro-1H-imidazol-2-yl)nitrous amide

Tizanidine Impurity 46
Formula: C9H7ClN6OS
282.71
RM-T092646
5-chloro-N-(1-nitroso-4,5-dihydro-1H-imidazol-2-yl)benzo[c][1,2,5]thiadiazol-4-amine

Tizanidine Impurity 47
Formula: C14H12Cl2N8S2
427.33
RM-T092647
2-(1,3-bis(5-chlorobenzo[d][1,2,3]thiadiazol-4-yl)triazan-2-yl)ethan-1-amine

Tizanidine Impurity 48
Formula: C12H16N6
244.3
RM-T092648
N1,N2-bis(4,5-dihydro-1H-imidazol-2-yl)benzene-1,2-diamine

Tizanidine Impurity 49
Formula: C9H9ClN4O2
240.65
RM-T092649
N-(5-chloro-2-nitrophenyl)-4,5-dihydro-1H-imidazol-2-amine

Tizanidine Nitroso Impurity 50
Formula: C10H6ClN5OS
279.7
RM-T092650
5-chloro-N-(1-nitroso-1H-pyrrol-2-yl)benzo[c][1,2,5]thiadiazol-4-amine

TIZANIDINE-D4
CAS:1188331-19-2
Formula: C9H4D4ClN5S
257.73
RM-T092622
5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl-4,4,5,5-d4)benzo[c][1,2,5]thiadiazol-4-amine

TNCA
CAS:42438-90-4
Formula: C12H12N2O2
216.24
RG-A260738
TNCA

TOBRAMYCIN
CAS:32986-56-4
Formula: C18H37N5O9
467.51
RM-T150200
Nebramycin factor 6; 3GÇ¦-Deoxykanamycin B; D-Streptamine, O-3-amino-3-deoxy-+¦-D-glucopyranosyl-(1GåÆ6)-O-[2,6-diamino-2,3,6-trideoxy-+¦-D-ribo-hexopyranosyl-(1GåÆ4)]-2-deoxy-; (2S,3R,4S,5S,6R)-4-amino-2-(((1S,2S,3R,4S,6R)-4,6-diamino-3-(((2R,3R,5

Tobramycin A; Deoxystreptamine Kanosaminide
CAS:20744-51-8
Formula: C12H25N3O7
323.34
RM-T150201
(2S,3R,4S,5S,6R)-4-amino-2-(((1S,2S,3R,4S,6R)-4,6-diamino-2,3-dihydroxycyclohexyl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diol

TOBRAMYCIN IMPURITY 10
CAS:51736-77-7
Formula: C19H38N6O10
510.54
RM-T150210
((2R,3S,4S,5R,6S)-4-amino-6-(((1S,2S,3R,4S,6R)-4,6-diamino-3-(((2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxytetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-3,5-dihydroxytetrahydro-2H-pyran-2-yl)methyl carbamate

Tobramycin Impurity 11
Formula: C19H38N6O10
510.54
RM-T150211
1-((1S,2R,3R,4S,5R)-5-amino-4-(((2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-(((2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxytetrahydro-2H-pyran-2-yl)oxy)-3-hydroxycyclohexyl)urea

Tobramycin Impurity 12
CAS:64332-33-8
Formula: C19H38N6O10
510.55
RM-T150212
D-Streptamine, O-6-amino-2-[(aminocarbonyl)amino]-2,3,6-trideoxy-+¦-D-ribo-hexopyranosyl-(1GåÆ4)-O-[3-amino-3-deoxy-+¦-D-glucopyranosyl-(1GåÆ6)]-2- deoxy- (9CI)

Tobramycin Impurity 13
Formula: C19H38N6O10
510.55
RM-T150213
1-((2R,3R,5S,6R)-6-(aminomethyl)-2-(((1R,2S,3S,4R,6S)-4,6-diamino-3-(((2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-5-hydroxytetrahydro-2H-pyran-3-yl)urea

Tobramycin Impurity 14
Formula: C19H38N6O10
510.55
RM-T150214
1-((1S,2R,3R,4S,5R)-5-amino-4-(((3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-(((2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxytetrahydro-2H-pyran-2-yl)oxy)-3-hydroxycyclohexyl)urea

Tobramycin Impurity 15
Formula: C19H38N6O10
510.55
RM-T150215
1-((1S,2R,3R,4S,5R)-5-amino-4-(((2R,3S,4R,5R,6S)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-(((2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxytetrahydro-2H-pyran-2-yl)oxy)-3-hydroxycyclohexyl)urea

Tobramycin Impurity 16
Formula: C19H38N6O10
510.55
RM-T150216
1-((1S,2R,3S,4S,5R)-5-amino-4-(((2S,3R,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-(((2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxytetrahydro-2H-pyran-2-yl)oxy)-3-hydroxycyclohexyl)urea

Tobramycin Impurity 17
Formula: C19H38N6O10
510.55
RM-T150217
1-((1S,2R,3R,4S,5R)-5-amino-4-(((2S,3R,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-(((3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxytetrahydro-2H-pyran-2-yl)oxy)-3-hydroxycyclohexyl)urea

Tobramycin Impurity 18
Formula: C12H27N3O7
325.36
RM-T150218
(2S,3R,4S,5S,6R)-4-amino-2-(((2R,4S,5R)-2,4-diamino-5,6-dihydroxyhexyl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diol

Tobramycin Impurity 19
CAS:74501-86-3
Formula: C18H35N5O8
449.51
RM-T150219
(2R,3S,4R,5R,6S)-4-amino-2-(((1S,2S,3R,4S,6R)-4,6-diamino-3-(((2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diol

Tobramycin Impurity 20
CAS:111170-72-0
Formula: C6H14N2O3
162.19
RM-T150220
(2R,4S,5R)-2,6-diamino-4,5-dihydroxyhexanal

Tobramycin Impurity 21
Formula: C20H40N6O9
508.57
RM-T150221
((2R,3S,4S,5R,6R)-4-amino-6-(((1S,2R,3R,4R,6S)-4,6-diamino-3-(((2R,3S,5R,6S)-3-amino-6-(aminomethyl)-5-hydroxytetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)methyl)-3,5-dihydroxytetrahydro-2H-pyran-2-yl)methyl carbamate

Tobramycin Impurity 22
Formula: C19H38N6O10
510.55
RM-T150222
1-((1S,2R,3R,4S,5R)-5-amino-4-(((2S,3R,4R,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-(((2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxytetrahydro-2H-pyran-2-yl)oxy)-3-hydroxycyclohexyl)urea

Tobramycin Impurity 23
Formula: C12H25N3O7
323.35
RM-T150223
(2S,3R,4R,5S,6R)-4-amino-2-(((1S,2S,3R,4S,6R)-4,6-diamino-2,3-dihydroxycyclohexyl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diol

Tobramycin Impurity 24
CAS:19309-98-9
Formula: C6H13NO5
179.17
RM-T150224
(3R,4S,5S,6R)-4-amino-6-(hydroxymethyl)tetrahydro-2H-pyran-2,3,5-triol

Tobramycin Impurity 25
CAS:52850-89-2
Formula: C6H14N2O3
162.19
RM-T150225
(2S,3R,5S,6R)-3-amino-6-(aminomethyl)tetrahydro-2H-pyran-2,5-diol

Tobramycin Impurity 26
Formula: C24H47N5O10
565.67
RM-T150226
((2R,3S,4S,5R,6S)-4-amino-6-(((1S,2S,3R,4S,6R)-4,6-diamino-3-(((2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxytetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-3,5-dihydroxytetrahydro-2H-pyran-2-yl)methyl hexanoate

Tobramycin Impurity 27
Formula: C24H47N5O10
565.67
RM-T150227
N-((2R,3R,5S,6R)-6-(aminomethyl)-2-(((1R,2S,3S,4R,6S)-4,6-diamino-3-(((2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-5-hydroxytetrahydro-2H-pyran-3-yl)hexanamide

Tobramycin Impurity 28
Formula: C30H49N7O14
731.76
RM-T150228
((2R,3S,4S,5R,6S)-4-amino-6-(((1S,2S,3R,4S,6R)-4,6-diamino-3-(((2R,3R,5S,6R)-3-amino-6-(((2,4-dinitrophenyl)amino)methyl)-5-hydroxytetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-3,5-dihydroxytetrahydro-2H-pyran-2-yl)methyl hexanoate

Tobramycin Impurity 29
Formula: C30H49N7O14
731.76
RM-T150229
N-((2R,3R,5S,6R)-2-(((1R,2S,3S,4R,6S)-4,6-diamino-3-(((2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-6-(((2,4-dinitrophenyl)amino)methyl)-5-hydroxytetrahydro-2H-pyran-3-yl)hexa

TOCERANIB
CAS:356068-94-5
Formula: C22H25FN4O2
396.46
RM-T152700
(Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-N-(2-(pyrrolidin-1-yl)ethyl)-1H-pyrrole-3-carboxamide

Toceranib Impurity 1
Formula: C28H22Cl2FNO3
510.39
RM-T152701
cyano(4-fluoro-3-phenoxyphenyl)methyl (1R,3R)-3-((Z)-2-chloro-2-(4-chlorophenyl)vinyl)-2,2-dimethylcyclopropane-1-carboxylate

Toceranib Impurity 2
Formula: C28H22Cl2FNO3
510.39
RM-T152702
cyano(4-fluoro-3-phenoxyphenyl)methyl (1S,3S)-3-((Z)-2-chloro-2-(4-chlorophenyl)vinyl)-2,2-dimethylcyclopropane-1-carboxylate

Tocopherol Impurity 60
CAS:113892-09-4
Formula: C29H48O2
428.7
RG-A262148
(R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-2H-chromen-6-ol

TOCOPHEROL IMPURITY 61
CAS:185672-33-7
Formula: C29H50O2
430.71
RM-T031861
2,3,4,6,7-pentamethyl-2-(4,8,12-trimethyltridecyl)-2,3-dihydrobenzofuran-5-ol

Tocopherol Impurity 63
CAS:3808-26-2
Formula: C29H48O2
428.7
RM-T031863
2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-chromen-6-ol

Tocopherol Impurity 64
CAS:75917-94-1
Formula: C29H50O2
430.72
RM-T031864
2,3,5-trimethyl-6-(3,7,11,15-tetramethylhexadecyl)cyclohexa-2,5-diene-1,4-dione

Tocopherol Impurity 65
CAS:72657-56-8
Formula: C29H50O3
446.72
RM-T031865
2-(3-hydroxy-3,7,11,15-tetramethylhexadecyl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione

Tocopherol Impurity 66
Formula: C29H50O2
430.72
RM-T031866
(2R,3S)-2,3,4,6,7-pentamethyl-2-(4,8,12-trimethyltridecyl)-2,3-dihydrobenzofuran-5-ol

Tocopherol Impurity 67
CAS:1560705-69-2
Formula: C29H50O2
430.72
RM-T031867
(2R,3R)-2,3,4,6,7-pentamethyl-2-(4,8,12-trimethyltridecyl)-2,3-dihydrobenzofuran-5-ol

Tocopherol Impurity 68
Formula: C29H50O2
430.72
RM-T031868
2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-ol

Tocopherol Impurity 73
Formula: C29H50O2
430.72
RM-T031873
(2S,3R)-2,3,4,6,7-pentamethyl-2-(4,8,12-trimethyltridecyl)-2,3-dihydrobenzofuran-5-ol

Tocopherol Impurity 74
Formula: C29H50O2
430.72
RM-T031874
(2S,3S)-2,3,4,6,7-pentamethyl-2-(4,8,12-trimethyltridecyl)-2,3-dihydrobenzofuran-5-ol

Tocopherol Impurity 75
Formula: C29H52O2
432.73
RM-T031875
3-(3-hydroxy-3-methylnonadecyl)-2,5,6-trimethylphenol

Tocopherol Impurity 77
CAS:69371-91-1
Formula: C29H52O2
432.73
RM-T031877
3-(3-hydroxy-3,7,11,15-tetramethylhexadecyl)-2,5,6-trimethylphenol

Tocopherol Impurity 78
CAS:2896-55-1
Formula: C58H98O4
859.42
RM-T031878
(2R,2'R)-5,5'-(ethane-1,2-diyl)bis(2,7,8-trimethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-ol)

Tocopherol Impurity 79
CAS:1604-73-5
Formula: C58H96O4
857.4
RM-T031879
(2R,8'R)-2,5',6',7,8,8'-hexamethyl-2,8'-bis((4R,8R)-4,8,12-trimethyltridecyl)-1',3,4,8',9',10'-hexahydro-2'H-spiro[chromene-5,3'-pyrano[3,2-f]chromen]-6(2H)-one

TOFACITINIB CITRATE
CAS:540737-29-9
Formula: C16H20N6O*C6H8O7
312.38*192.12
RM-T060300
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile 2-hydroxypropane-1,2,3-tricarboxylate

Tofacitinib Impurity 100
CAS:2102039-99-4
Formula: C21H27N7O3
425.48
RM-T060400
ethyl 4-cyano-3-imino-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopentanoate

Tofacitinib Impurity 101
Formula: C21H27N7O3
425.48
RM-T060401
(E)-ethyl 5-amino-2-cyano-3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopent-2-enoate

Tofacitinib Impurity 102
Formula: C21H27N7O3
425.48
RM-T060402
3-ethoxy-3-hydroxy-2-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carbonyl)pentanedinitrile

Tofacitinib Impurity 103
Formula: C23H31N7O3
453.54
RM-T060403
3-butoxy-3-hydroxy-2-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carbonyl)pentanedinitrile

Tofacitinib Impurity 104
Formula: C12H5Cl3N6
339.57
RM-T060404
2,2',4'-trichloro-7H-4,7'-bipyrrolo[2,3-d]pyrimidine

Tofacitinib Impurity 105
Formula: C12H8N6
236.23
RM-T060405
7H-4,7'-bipyrrolo[2,3-d]pyrimidine

Tofacitinib Impurity 106
Formula: C16H21ClN6O
348.83
RM-T060406
3-((3R,4R)-3-((2-chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

Tofacitinib Impurity 107
Formula: C21H26ClN7O3
459.93
RM-T060407
(E)-ethyl 3-amino-5-((3R,4R)-3-((2-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-2-cyano-5-oxopent-2-enoate

Tofacitinib Impurity 108
CAS:2282653-53-4
Formula: C8H9ClN4
196.64
RM-T060408
2-chloro-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 109
Formula: C8H10N4
162.19
RM-T060409
N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY 11
CAS:2250241-69-9
Formula: C13H11N3O3S
289.31
RM-T050241
7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-ol

TOFACITINIB IMPURITY 111
CAS:1615709-90-4
Formula: C14H17ClN2
248.75
RM-T060411
1-benzyl-4-methyl-3-(methylamino)pyridin-1-ium chloride

TOFACITINIB IMPURITY 112
Formula: C21H28N2
308.46
RM-T060412
N,1-dibenzyl-N,4-dimethylpiperidin-3-amine

Tofacitinib Impurity 113
Formula: C6H5N3OS
167.19
RM-T060413
2-mercapto-7H-pyrrolo[2,3-d]pyrimidin-4-ol

TOFACITINIB IMPURITY 114
CAS:3680-71-5
Formula: C6H5N3O
135.12
RM-T060414
7H-Pyrrolo[2,3-d]pyrimidin-4-ol

Tofacitinib Impurity 115
CAS:934524-10-4
Formula: C13H9Cl2N3O2S
342.2
RM-T060415
2,4-Dichloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine

Tofacitinib Impurity 116
Formula: C13H10ClN3O2S
307.76
RM-T060416
2-chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine

Tofacitinib Impurity 117
Formula: C13H11N3O2S
273.31
RM-T060417
7-tosyl-7H-pyrrolo[2,3-d]pyrimidine

Tofacitinib Impurity 118
CAS:2504210-48-2
Formula: C22H23N9O
429.48
RM-T060418
3-((3R,4R)-3-(7H-[4,7'-bipyrrolo[2,3-d]pyrimidin]-4'-yl(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

Tofacitinib Impurity 119
CAS:2459302-86-2
Formula: C19H22N8
362.43
RM-T060419
N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-[4,7'-bipyrrolo[2,3-d]pyrimidin]-4'-amine

TOFACITINIB IMPURITY 12
CAS:2227199-28-0
Formula: C14H19N5O
273.33
RM-T060338
(3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carbaldehyde

Tofacitinib Impurity 120
Formula: C20H24ClN5
369.89
RM-T060420
N-((3S,4S)-1-benzyl-4-methylpiperidin-3-yl)-4-chloro-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine

Tofacitinib Impurity 121
CAS:6066-82-6
Formula: C4H5NO3
115.09
RM-T060421
1-hydroxypyrrolidine-2,5-dione

TOFACITINIB IMPURITY 122
Formula: C16H20N6O
312.37
RM-T060422
2-cyano-N-methyl-N-((3R,4S)-3-methyl-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl)acetamide

TOFACITINIB IMPURITY 123
CAS:1092578-43-2
Formula: C16H20N6O
312.37
RM-T060423
2-cyano-N-methyl-N-((3R,4R)-4-methyl-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl)acetamide

TOFACITINIB IMPURITY 124
Formula: C14H21ClN2
252.78
RM-T060424
1-benzyl-4-methyl-3-(methylamino)-2,3,4,5-tetrahydropyridin-1-ium chloride

TOFACITINIB IMPURITY 125
Formula: C14H18N2
214.31
RM-T060425
1-benzyl-N,4-dimethyl-1,6-dihydropyridin-3-amine

TOFACITINIB IMPURITY 126
Formula: C14H22N2O
234.34
RM-T060426
1-benzyl-4-methyl-3-(methylamino)piperidin-4-ol

TOFACITINIB IMPURITY 127
Formula: C13H19N
189.3
RM-T060427
1-benzyl-4-methylpiperidine

TOFACITINIB IMPURITY 128
Formula: C14H22N2
218.34
RM-T060428
N-benzyl-N,4-dimethylpiperidin-3-amine

TOFACITINIB IMPURITY 129
Formula: C14H22N2
218.34
RM-T060429
1-benzyl-N,3-dimethylpiperidin-4-amine

TOFACITINIB IMPURITY 13
CAS:134965-85-8
Formula: C12H7ClN6
270.68
RM-T060337
4'-chloro-7H-4,7'-bipyrrolo[2,3-d]pyrimidine

TOFACITINIB IMPURITY 130
CAS:384338-20-9(free base)
Formula: C13H19NO C7H8O3S
205.30 172.20
RM-T060430
1-benzyl-4-methylpiperidin-3-ol 4-methylbenzenesulfonate

Tofacitinib Impurity 131
Formula: C26H35N9O2
505.62
RM-T060431
3,3'-((3R,3'R,4R,4'R)-((7H-pyrrolo[2,3-d]pyrimidine-2,4-diyl)bis(methylazanediyl))bis(4-methylpiperidine-3,1-diyl))bis(3-oxopropanenitrile)

TOFACITINIB IMPURITY 132
CAS:923036-25-3
Formula: C20H24ClN5
369.89
RM-T060432
N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-2-chloro-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY 133
CAS:344418-92-4(free base)
Formula: C16H20N6O C6H8O7
312.37 192.12
RM-T060433
3-(4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile 2-hydroxypropane-1,2,3-tricarboxylate

TOFACITINIB IMPURITY 136
CAS:2407039-29-4
Formula: C16H20N6O2
328.37
RM-T060436
3-((3R,4R)-3-((7-hydroxy-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

Tofacitinib Impurity 137
CAS:2106832-55-5
Formula: C14H22N2 2HCl
218.34 72.92
RM-T060437
(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride/(3S,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride

Tofacitinib Impurity 138
CAS:1204176-45-3
Formula: C8H16N2O2
172.22
RM-T060438
Methyl (4-methylpiperidin-3-yl)carbamate

Tofacitinib Impurity 139
Formula: C13H19N5
245.32
RM-T060439
(3S,4R)-N,4-dimethyl-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-amine

TOFACITINIB IMPURITY 14
Formula: C15H21N5O
287.36
RM-T060339
3-(3-((4-aminopyridin-2-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

Tofacitinib Impurity 140
Formula: C13H19N5
245.32
RM-T060440
(3R,4R)-N,4-Dimethyl-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-amine

Tofacitinib Impurity 141
Formula: C10H14N2O4
226.23
RM-T060441
(Z)-diethyl 3-amino-2-cyanopent-2-enedioate

Tofacitinib Impurity 143
CAS:32634-66-5
Formula: C20H18O8
386.35
RM-T060443
(2R,3R)-2,3-bis((4-methylbenzoyl)oxy)succinic acid

Tofacitinib Impurity 144
Formula: C15H20ClN5O
321.81
RM-T060444
2-chloro-1-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)ethanone

Tofacitinib Impurity 145
Formula: C16H22N6O3
346.38
RM-T060445
3-((3R,4R)-3-((5,6-dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

Tofacitinib Impurity 146
CAS:2102040-00-4
Formula: C32H40N12O2
624.74
RM-T060446
3-imino-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-2-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carbonyl)-5-oxopentanenitrile

Tofacitinib Impurity 147
CAS:2101951-20-4
Formula: C16H20N6O2
328.37
RM-T060447
3-((3R,4R)-4-methyl-3-(methyl(5-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

TOFACITINIB IMPURITY 148
CAS:1615709-89-1
Formula: C14H17N2 Br
213.30 79.90
RM-T060448
1-benzyl-4-methyl-3-(methylamino)pyridin-1-ium bromide

Tofacitinib Impurity 149
CAS:861612-04-6
Formula: C8H8N2O3
180.16
RM-T060449
(Z)-ethyl 2,4-dicyano-3-hydroxybut-2-enoate

Tofacitinib Impurity 150
Formula: C27H31N5O2S
489.63
RM-T060450
N-((3S,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine/N-((3R,4S)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY 151
Formula: C27H31N5
425.57
RM-T060451
7-benzyl-N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 152
Formula: C19H27N5O3
373.45
RM-T060452
ethyl 4-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-4-oxobutanoate

TOFACITINIB IMPURITY 153
CAS:2032-35-1
Formula: C6H13BrO2
197.07
RM-T060453
2-Bromo-1,1-diethoxyethane

TOFACITINIB IMPURITY 154
Formula: C4H4N3NaOS
165.15
RM-T060454
sodium 6-amino-2-mercaptopyrimidin-4-olate

TOFACITINIB IMPURITY 155
Formula: C4H5N3O
111.1
RM-T060455
6-Aminopyrimidin-4-ol

Tofacitinib Impurity 156
Formula: C10H17N3O3
227.26
RM-T060456
6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol

Tofacitinib Impurity 157
CAS:7400-05-7
Formula: C10H17N3O3S
259.33
RM-T060457
6-Amino-5-(2,2-diethoxyethyl)-2-mercaptopyrimidin-4-ol

Tofacitinib Impurity 158
Formula: C20H24ClN5
369.89
RM-T060458
N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-4-chloro-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine

Tofacitinib Impurity 159
Formula: C20H25N7O3
411.46
RM-T060459
(Z)-methyl 3-amino-2-cyano-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopent-2-enoate

TOFACITINIB IMPURITY 16
CAS:2504210-41-5
Formula: C29H38N10O2
558.68
RM-T060341
1,3-bis((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)propane-1,3-dione

Tofacitinib Impurity 160
Formula: C6H4Cl3N3
224.48
RM-T060460
(Z)-2,6-dichloro-N-(2-chloroethylidene)pyrimidin-4-amine

TOFACITINIB IMPURITY 161
Formula: C6H7Cl2N3O2
224.04
RM-T060461
2-((2,6-dichloropyrimidin-4-yl)amino)ethane-1,1-diol

TOFACITINIB IMPURITY 162
CAS:2459302-88-4
Formula: C20H29N5O3
387.48
RM-T060462
tert-butyl 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoate

TOFACITINIB IMPURITY 163
Formula: C23H31N7O3
453.54
RM-T060463
(E)-tert-butyl 3-amino-2-cyano-5-((3S,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopent-2-enoate

TOFACITINIB IMPURITY 164
CAS:2504210-49-3
Formula: C20H24ClN5
369.9
RM-T060464
N-((3S,4R)-1-benzyl-4-methylpiperidin-3-yl)-4-chloro-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine

Tofacitinib Impurity 166
CAS:1638499-36-1
Formula: C15H20N2O
244.34
RM-T060466
N-(1-benzyl-4-methyl-1,2,5,6-tetrahydropyridin-3-yl)acetamide

TOFACITINIB IMPURITY 167
Formula: C10H17N3O
195.27
RM-T060467
2-cyano-N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)acetamide

TOFACITINIB IMPURITY 168
Formula: C27H36N8O2
504.64
RM-T060468
3,3'-((3R,3'R,4R,4'R)-((1H-pyrrolo[2,3-c]pyridine-5,7-diyl)bis(methylazanediyl))bis(4-methylpiperidine-3,1-diyl))bis(3-oxopropanenitrile)

TOFACITINIB IMPURITY 169
CAS:2564-07-0
Formula: C10H12ClNO
197.66
RG-C081234
2-chloro-N-(2,3-dimethylphenyl)acetamide

TOFACITINIB IMPURITY 17
CAS:2459302-77-1
Formula: C19H21N7O2
379.42
RM-T060342
3-(4-(((3R,4R)-1-(2-Cyanoacetyl)-4-methylpiperidin-3-yl)(methyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-oxopropanenitrile

TOFACITINIB IMPURITY 170
Formula: C14H22N2O
234.34
RM-T060469
(3S)-1-benzyl-4-methyl-3-(methylamino)piperidin-4-ol

TOFACITINIB IMPURITY 171
Formula: C20H25N5O
351.45
RM-T060470
4-(((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)(methyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-2-ol

Tofacitinib Impurity 172
Formula: C6H3Cl2N3
188.01
RM-T060471
4,6-dichloro-7H-pyrrolo[2,3-d]pyrimidine

Tofacitinib Impurity 173
CAS:2504210-32-4
Formula: C13H18ClN5
279.77
RM-T060501
(3R,4R)-1-(2-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-N,4-dimethylpiperidin-3-amine

Tofacitinib Impurity 174
Formula: C19H20Cl2N8
431.33
RM-T060502
2-chloro-N-((3R,4R)-1-(2-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 175
Formula: C20H27N5
337.47
RM-T060503
N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 176
CAS:2504210-34-6
Formula: C20H26ClN5
371.91
RM-T060504
N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-2-chloro-N-methyl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 177
Formula: C11H4Cl3N7
340.55
RM-T060505
2-chloro-6-(2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-9H-purine

Tofacitinib Impurity 178
Formula: C6H5Cl2N3O
206.03
RM-T060506
2-((2,6-dichloropyrimidin-4-yl)amino)acetaldehyde

Tofacitinib Impurity 179
Formula: C13H20ClN5
281.79
RM-T060507
2-chloro-N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY 18
CAS:2028267-73-2
Formula: C16H20N6O2
328.37
RM-T060343
N-((3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine oxide

Tofacitinib Impurity 180
Formula: C13H18ClN5
279.77
RM-T060508
2-chloro-N-methyl-N-((3S,4S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 181
Formula: C13H18ClN5
279.77
RM-T060509
2-chloro-N-methyl-N-((3S,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 182
Formula: C13H18ClN5
279.77
RM-T060510
2-chloro-N-methyl-N-((3R,4S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 183
Formula: C20H33N7
371.53
RM-T060511
N2,N4-dimethyl-N2,N4-bis((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine

Tofacitinib Impurity 184
Formula: C34H42N10O2
622.78
RM-T060512
3-((3R,4R)-3-((1H-indol-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-hydroxy-2-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carbonyl)pentanedinitrile

Tofacitinib Impurity 185
CAS:221221-30-3
Formula: C6H14N2
114.19
RM-T060513
4-methylpiperidin-3-amine

Tofacitinib Impurity 186
Formula: C13H20N2
204.32
RM-T060514
N-benzyl-4-methylpiperidin-3-amine

Tofacitinib Impurity 187
Formula: C14H22N2
218.34
RM-T060515
(3S,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine

TOFACITINIB IMPURITY 188
Formula: C34H45N7
551.78
RM-T060516
N4-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N2-((3S,4S)-1-benzyl-4-methylpiperidin-3-yl)-N2,N4-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine

TOFACITINIB IMPURITY 189
Formula: C14H20N6O
288.36
RM-T060517
3-((3S,4R)-3-((6-aminopyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

TOFACITINIB IMPURITY 19
Formula: C14H22N2O
234.34
RM-T060344
((1-benzyl-4-methylpiperidin-3-yl)amino)methanol

TOFACITINIB IMPURITY 190
Formula: C14H20N6O
288.36
RM-T060518
3-((3R,4S)-3-((6-aminopyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

TOFACITINIB IMPURITY 191
CAS:2183519-70-0
Formula: C15H23N5
273.38
RM-T060519
N-((3R,4R)-1-ethyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY 192
Formula: C17H23N5O2
329.4
RM-T060520
1-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)butane-1,3-dione

Tofacitinib Impurity 193
Formula: C17H26ClN5
335.88
RM-T060521
N-((3R,4R)-1-butyl-4-methylpiperidin-3-yl)-2-chloro-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 194
CAS:477600-69-4
Formula: C14H22N2
218.34
RM-T060522
3-Piperidinamine, N,4-dimethyl-1-(phenylmethyl)-, (3R,4R)-rel-

Tofacitinib Impurity 195
Formula: C19H13ClN6O2S
424.86
RM-T060523
4'-chloro-7-tosyl-7H-4,7'-bipyrrolo[2,3-d]pyrimidine

Tofacitinib Impurity 196
Formula: C22H29N5
363.51
RM-T060524
N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-7-ethyl-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY 197
Formula: C14H21N5
259.36
RM-T060525
N,7-dimethyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY 198
CAS:2641343-91-9
Formula: C21H27N5
349.48
RM-T060526
N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N,7-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 199
CAS:2639657-79-5
Formula: C23H31N5
377.54
RM-T060527
N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-7-isopropyl-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY 20
CAS:1092578-48-7+1092578-46-5
Formula: C16H20N6O*2
312.38*2
RM-T060345
3-((3R,4S)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile--3-((3S,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile (1/1)

Tofacitinib Impurity 200
CAS:2639657-81-9
Formula: C16H25N5
287.41
RM-T060528
7-isopropyl-N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY 201
Formula: C16H25N5
287.41
RM-T060529
N-((3R,4R)-1-isopropyl-4-methylpiperidin-3-yl)-N-methyl-1H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 202
CAS:1325182-06-6
Formula: C20H25N5O2S
399.51
RM-T060530
N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 203
Formula: C18H27BN4O4
374.25
RM-T060531
isopropyl 3-(cyanomethyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)azetidine-1-carboxylate

Tofacitinib Impurity 204
Formula: C24H34B2N6O5
508.19
RM-T060532
2-(3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carbonyl)azetidin-3-yl)acetonitrile

Tofacitinib Impurity 205
Formula: C18H24B2N6O5
426.05
RM-T060533
(1-(3-(cyanomethyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)azetidine-1-carbonyl)-1H-pyrazol-4-yl)boronic acid

Tofacitinib Impurity 206
Formula: C12H14B2N6O5
343.9
RM-T060534
(1-(1-(4-borono-1H-pyrazole-1-carbonyl)-3-(cyanomethyl)azetidin-3-yl)-1H-pyrazol-4-yl)boronic acid

Tofacitinib Impurity 207
Formula: C9H9BN4O3
232.01
RM-T060535
(1-(3-(cyanomethylene)azetidine-1-carbonyl)-1H-pyrazol-4-yl)boronic acid

TOFACITINIB IMPURITY 208
Formula: C15H19BN4O3
314.15
RM-T060536
2-(1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carbonyl)azetidin-3-ylidene)acetonitrile

Tofacitinib Impurity 209
Formula: C26H34N8O4
522.61
RM-T060537
di-tert-butyl 3,3'-(1H,1'H-[4,4'-bipyrazole]-1,1'-diyl)bis(3-(cyanomethyl)azetidine-1-carboxylate)

TOFACITINIB IMPURITY 21
CAS:2259288-22-5
Formula: C23H26N6O3S
466.56
RM-T060347
3-((3R,4R)-4-methyl-3-(methyl(7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

Tofacitinib Impurity 210
Formula: C25H24N10O2
496.54
RM-T060538
tert-butyl 3-(4-(7H-[4,7'-bipyrrolo[2,3-d]pyrimidin]-4'-yl)-1H-pyrazol-1-yl)-3-(cyanomethyl)azetidine-1-carboxylate

Tofacitinib Impurity 211
Formula: C12H8N6
236.24
RM-T060539
7H,7'H-4,4'-bipyrrolo[2,3-d]pyrimidine

Tofacitinib Impurity 212
CAS:2280085-84-7
Formula: C30H41N11O2
587.73
RM-T060540
2,2'-azanediylbis(1-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)ethan-1-one)

Tofacitinib Impurity 213
Formula: C25H32ClN5O2
470.01
RM-T060541
tert-butyl 2-(((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)(methyl)amino)-4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate

Tofacitinib Impurity 214
Formula: C39H53N7O2
651.9
RM-T060542
tert-butyl 2,4-bis(((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)(methyl)amino)-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate

Tofacitinib Impurity 215
CAS:2716897-36-6
Formula: C23H31N7O3
453.55
RM-T060543
butyl 3-amino-2-cyano-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopent-2-enoate

Tofacitinib Impurity 216
Formula: C30H41N11O2
587.73
RM-T060544
2,2'-azanediylbis(1-((3S,4S)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)ethan-1-one)

Tofacitinib Impurity 217
CAS:1245811-22-6
Formula: C6H4ClN3O
169.57
RM-T060545
2-chloro-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one

Tofacitinib Impurity 218
Formula: C22H28N2O
336.48
RM-T060546
N-((3S,4S)-1-benzyl-4-methylpiperidin-3-yl)-N,4-dimethylbenzamide

Tofacitinib Impurity 219
Formula: C21H28N2
308.47
RM-T060547
(3R,4R)-N,1-dibenzyl-N,4-dimethylpiperidin-3-amine

TOFACITINIB IMPURITY 22
CAS:1640972-35-5
Formula: C16H22N6O
314.39
RM-T060348
3-((3R,4R)-3-((6,7-Dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

TOFACITINIB IMPURITY 220
Formula: C16H26N2
246.4
RM-T060548
(3R,4R)-1-benzyl-N-ethyl-N,4-dimethylpiperidin-3-amine

Tofacitinib Impurity 222
Formula: C33H34N8O2S
606.75
RM-T060550
N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-[4,7'-bipyrrolo[2,3-d]pyrimidin]-4'-amine

Tofacitinib Impurity 223
Formula: C30H40N10O2
572.72
RM-T060551
1,4-bis((3S,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)butane-1,4-dione

Tofacitinib Impurity 224
Formula: C30H40N10O2
572.72
RM-T060552
1,4-bis((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)butane-1,4-dione

Tofacitinib Impurity 225
Formula: C26H28N8O2S
516.62
RM-T060553
N-methyl-N-((3R,4R)-4-methyl-1-(7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 226
Formula: C16H19ClN6O
346.82
RM-T060554
3-((3R,4R)-3-((4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

Tofacitinib Impurity 227
Formula: C13H18ClN5
279.77
RM-T060555
4-chloro-N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine

Tofacitinib Impurity 228
Formula: C27H30ClN5O2S
524.08
RM-T060556
N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-2-chloro-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 229
Formula: C20H24ClN5O2S
433.96
RM-T060557
2-chloro-N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY 23
CAS:1640971-60-3
Formula: C14H20N6O
288.35
RM-T060349
3-((3R,4R)-3-((6-Aminopyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

Tofacitinib Impurity 230
Formula: C27H30ClN5O2S
524.08
RM-T060558
N-(1-benzyl-4-methylpiperidin-3-yl)-2-chloro-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 231
Formula: C6H7N5
149.16
RM-T060559
4-hydrazineyl-7H-pyrrolo[2,3-d]pyrimidine

Tofacitinib Impurity 232
Formula: C13H13N5O2S
303.34
RM-T060560
4-hydrazineyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine

Tofacitinib Impurity 233
Formula: C20H25N7O3
411.47
RM-T060561
methyl (E)-3-amino-2-cyano-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopent-2-enoate

Tofacitinib Impurity 234
CAS:1629858-78-1
Formula: C10H17N3O
195.27
RM-T060562
3-((3R,4R)-4-Methyl-3-(methylamino)piperidin-1-yl)-3-oxopropanenitrile

Tofacitinib Impurity 235
CAS:1206875-42-4
Formula: C10H17N3O
195.27
RM-T060563
3-(4-methyl-3-(methylamino)piperidin-1-yl)-3-oxopropanenitrile

Tofacitinib Impurity 236
Formula: C27H36N10O
516.65
RM-T060564
bis((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methanone

Tofacitinib Impurity 237
Formula: C20H22N8O2
406.45
RM-T060565
1H-benzo[d][1,2,3]triazol-1-yl (3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carboxylate

Tofacitinib Impurity 238
CAS:2106832-56-6
Formula: C14H20N2
216.33
RM-T060566
1-benzyl-N,4-dimethylpiperidin-3-imine

Tofacitinib Impurity 239
Formula: C34H45N7
551.78
RM-T060567
N2,N4-bis((3S,4R)-1-benzyl-4-methylpiperidin-3-yl)-N2,N4-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine

TOFACITINIB IMPURITY 24
CAS:2459302-85-1
Formula: C21H27N7O3
425.48
RM-T060350
(E)-ethyl 3-amino-2-cyano-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopent-2-enoate

Tofacitinib Impurity 240
Formula: C6H5N3O2
151.13
RM-T060568
4-aminofuro[2,3-d]pyrimidin-2-ol

Tofacitinib Impurity 241
Formula: C15H18N6O*2
298.35*2
RM-T060569
3-((3R,4R)-3-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile--3-((3S,4S)-3-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

Tofacitinib Impurity 242
CAS:2374700-38-4
Formula: C20H25N5
335.46
RM-T060570
7H-Pyrrolo[2,3-d]pyrimidin-2-amine, N-methyl-N-[(3R,4R)-4-methyl- 1-(phenylmethyl)-3-piperidinyl]

Tofacitinib Impurity 243
CAS:1251908-67-4
Formula: C13H20N2
204.32
RM-T060571
(3R,4R)-1-benzyl-4-methylpiperidin-3-amine--(3S,4S)-1-benzyl-4-methylpiperidin-3-amine (1/1)

Tofacitinib Impurity 244
Formula: C26H29N5O2S
475.61
RM-T060572
N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine--N-((3S,4S)-1-benzyl-4-methylpiperidin-3-yl)-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine (1/1)

Tofacitinib Impurity 245
Formula: C19H23N5
321.43
RM-T060573
N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine--N-((3S,4S)-1-benzyl-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (1/1)

Tofacitinib Impurity 246
Formula: C15H22N2O2
262.35
RM-T060574
methyl ((3S,4S)-1-benzyl-4-methylpiperidin-3-yl)carbamate

Tofacitinib Impurity 247
Formula: C15H22N2O2
262.35
RM-T060575
methyl ((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)carbamate--methyl ((3S,4S)-1-benzyl-4-methylpiperidin-3-yl)carbamate (1/1)

Tofacitinib Impurity 248
Formula: C15H22N2O2
262.35
RM-T060576
methyl ((3R,4S)-1-benzyl-4-methylpiperidin-3-yl)carbamate--methyl ((3S,4R)-1-benzyl-4-methylpiperidin-3-yl)carbamate (1/1)

Tofacitinib Impurity 249
Formula: C8H13ClO4
208.64
RM-T060577
diethyl 2-chlorosuccinate

TOFACITINIB IMPURITY 25
Formula: C16H20N6O2
328.37
RM-T060351
N-((3S,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine oxide

Tofacitinib Impurity 250
CAS:377751-50-3
Formula: C8H13ClO4
208.64
RM-T060578
diethyl (R)-2-chlorosuccinate

Tofacitinib Impurity 251
Formula: C16H20N6O
312.38
RM-T060579
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile--3-((3S,4S)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile (1/1)

Tofacitinib Impurity 252
Formula: C13H19N5O
261.33
RM-T060580
(3S)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-4-ol

Tofacitinib Impurity 253
Formula: C20H24ClN5O
385.9
RM-T060581
(3S)-1-benzyl-3-((2-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-4-ol

Tofacitinib Impurity 254
CAS:2382711-65-9
Formula: C32H40N12O2
624.75
RM-T060582
3-amino-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-2-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carbonyl)-5-oxopent-2-enenitrile

Tofacitinib Impurity 255
Formula: C23H31N7O3
453.55
RM-T060583
tert-butyl (E)-3-amino-2-cyano-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopent-2-enoate

Tofacitinib Impurity 256
Formula: C14H20N6O
288.36
RM-T060584
3-((3R,4R)-3-((4-aminopyrimidin-2-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

Tofacitinib Impurity 257
CAS:1011723-46-8
Formula: C16H23N5O2
317.39
RM-T060585
2-methoxy-1-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)ethan-1-one

Tofacitinib Impurity 259
Formula: C13H20N6
260.35
RM-T060587
(3S)-N3,N4-dimethyl-N3-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-3,4-diamine

TOFACITINIB IMPURITY 26
CAS:1812890-23-5
Formula: C13H21N5
247.34
RM-T060352
N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 260
Formula: C20H25ClN6
384.91
RM-T060588
(3S)-1-benzyl-N3-(2-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-N3,N4-dimethylpiperidine-3,4-diamine

Tofacitinib Impurity 261
CAS:477600-71-8
Formula: C20H18O8 2C14H22N2
386.36 436.69
RM-T060589
3-bis(4-Methylbenzoyloxy)succinate); (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine hemi((2R,3R)-2,3-bis((4-methylbenzoyl)oxy)succinate)

Tofacitinib Impurity 262
CAS:84905-80-6
Formula: C6H4ClN3
153.57
RM-T060590
4-chloro-5H-pyrrolo[3,2-d]pyrimidine

Tofacitinib Impurity 263
CAS:186454-70-6
Formula: C6H5N3O
135.13
RM-T060591
furo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 264
CAS:7400-06-8
Formula: C10H17N3O3
227.26
RM-T060592
6-amino-5-(2,2-diethoxyethyl)pyrimidin-4(1H)-one

Tofacitinib Impurity 265
CAS:1269822-97-0
Formula: C6H5N3O
135.13
RM-T060593
7H-pyrrolo[2,3-c]pyridazin-4-ol

Tofacitinib Impurity 266
Formula: C16H19N7O2
341.38
RM-T060594
3-((3R,4R)-4-methyl-3-(methyl(7-nitroso-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

Tofacitinib Impurity 267
Formula: C14H20N6O
288.36
RM-T060595
3-((3R,4R)-3-((6-aminopyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile--3-((3S,4S)-3-((6-aminopyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile (1/1)

Tofacitinib Impurity 268
Formula: C16H20N6O2
328.38
RM-T060596
3-((3R,4R)-3-((7-hydroxy-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile--3-((3S,4S)-3-((7-hydroxy-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile (1/1)

Tofacitinib Impurity 269
Formula: C16H22N6O
314.39
RM-T060597
3-((3R,4R)-3-((6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile--3-((3S,4S)-3-((6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile (1/

TOFACITINIB IMPURITY 27
CAS:2227199-31-5
Formula: C20H29N5O3
387.48
RM-T060353
butyl 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoate

Tofacitinib Impurity 270
CAS:1236033-21-8
Formula: C11H12ClN3O2
253.69
RM-T060598
tert-butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate

Tofacitinib Impurity 271
Formula: C13H18N6O
274.33
RM-T060599
N-methyl-N-((3R,4R)-4-methyl-1-nitrosopiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 272
Formula: C10H16N4O2
224.26
RM-T060601
N-((3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl)-N-methylnitrous amide

Tofacitinib Impurity 273
Formula: C14H21N3O
247.34
RM-T060602
N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methylnitrous amide

Tofacitinib Impurity 274
Formula: C7H15N3O
157.22
RM-T060603
N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)nitrous amide

Tofacitinib Impurity 275
Formula: C7H14N4O2
186.22
RM-T060604
N-methyl-N-((3R,4R)-4-methyl-1-nitrosopiperidin-3-yl)nitrous amide

Tofacitinib Impurity 277
CAS:694495-64-2
Formula: C8H16N2O2
172.23
RM-T060606
methyl ((3R,4R)-4-methylpiperidin-3-yl)carbamate--methyl ((3S,4S)-4-methylpiperidin-3-yl)carbamate (1/1)

Tofacitinib Impurity 278
Formula: C10H12N2O3
208.22
RM-T060607
ethyl (Z)-2,4-dicyano-3-ethoxybut-2-enoate

Tofacitinib Impurity 279
Formula: C10H15N3O4
241.25
RM-T060608
5-(2,2-diethoxyethyl)-6-nitrosopyrimidin-4-ol

TOFACITINIB IMPURITY 28
Formula: C23H31N7O3
453.54
RM-T060354
(E)-butyl 3-amino-2-cyano-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopent-2-enoate

Tofacitinib Impurity 280
Formula: C14H16N2
212.3
RM-T060609
N-benzyl-N,4-dimethylpyridin-3-amine

Tofacitinib Impurity 281
CAS:67831-84-9
Formula: C6H5N3OS
167.19
RM-T060610
2-thioxo-1,2,3,7-tetrahydro-4H-pyrrolo[2,3-d]pyrimidin-4-one

Tofacitinib Impurity 282
Formula: C18H27N5O
329.45
RM-T060611
2,2-dimethyl-1-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)propan-1-one

Tofacitinib Impurity 283
Formula: C23H31N7O3
453.55
RM-T060612
butyl (E)-3-amino-2-cyano-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopent-2-enoate

Tofacitinib Impurity 284
Formula: C18H24ClN5
345.88
RM-T060613
N4-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-2-chloro-N4-methylpyrimidine-4,6-diamine

Tofacitinib Impurity 285
CAS:2518385-78-7
Formula: C25H32ClN5O2
470.01
RM-T060614
2-(3-(4-(4-chlorophenyl)piperazin-1-yl)propyl)-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

Tofacitinib Impurity 286
Formula: C16H22N6O4
362.39
RM-T060615
3-((3R,4R)-4-methyl-3-(methyl(2,5,6-trihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

TOFACITINIB IMPURITY 29
CAS:2504210-38-0
Formula: C19H22N8
362.43
RM-T060355
N-methyl-N-((3R,4R)-4-methyl-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY 30
Formula: C20H24ClN5
369.89
RM-T060356
N-((3S,4S)-1-benzyl-4-methylpiperidin-3-yl)-2-chloro-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY 31
Formula: C20H24ClN5
369.89
RM-T060357
N-((3R,4S)-1-benzyl-4-methylpiperidin-3-yl)-2-chloro-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY 32
Formula: C20H24ClN5
369.89
RM-T060358
N-((3S,4R)-1-benzyl-4-methylpiperidin-3-yl)-2-chloro-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY 33
Formula: C13H19N5
245.32
RM-T060359
N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine

TOFACITINIB IMPURITY 34
CAS:5305-59-9
Formula: C4H4ClN3
129.55
RM-T060472
6-chloropyrimidin-4-amine

TOFACITINIB IMPURITY 35
Formula: C6H6ClN3
155.59
RM-T060473
(E)-2-(4-chloropyrimidin-5-yl)ethen-1-amine

TOFACITINIB IMPURITY 36
Formula: C6H6ClN3
155.59
RM-T060474
6-chloro-5-vinylpyrimidin-4-amine

TOFACITINIB IMPURITY 37
Formula: C14H22N2O
234.34
RM-T060475
(3R)-1-benzyl-4-methyl-3-(methylamino)piperidin-4-ol

TOFACITINIB IMPURITY 40
Formula: C23H31N7O3
453.55
RM-T060478
butyl (Z)-3-amino-2-cyano-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopent-2-enoate

TOFACITINIB IMPURITY 41
Formula: C24H32N6O3
452.56
RM-T060480
butyl (E)-5-((3S,4R)-3-((S)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)ethyl)-4-methylpiperidin-1-yl)-3-amino-2-cyano-5-oxopent-2-enoate

TOFACITINIB IMPURITY 43
Formula: C6H4ClN3O
169.57
RM-T060481
4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-ol

TOFACITINIB IMPURITY 44
Formula: C6H4ClN3O
169.57
RM-T060482
2-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-ol

TOFACITINIB IMPURITY 45
CAS:1039738-27-6
Formula: C13H20N2
204.32
RM-T060483
1-benzyl-4-methylpiperidin-3-amine

TOFACITINIB IMPURITY 46
Formula: C19H22ClN5
355.87
RM-T060484
N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-2-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY 47
Formula: C16H20N6O2
328.38
RM-T060485
3-((3R,4R)-3-((2-hydroxy-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

TOFACITINIB IMPURITY 48
Formula: C14H21N5O
275.36
RM-T060486
((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methanol

TOFACITINIB IMPURITY 49
Formula: C17H22N6O
326.4
RM-T060487
3-((3R,4R)-4-methyl-3-(methyl(7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

TOFACITINIB IMPURITY 50
Formula: C32H40N12O2
624.75
RM-T060488
(Z)-3-amino-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-2-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carbonyl)-5-oxopent-2-enenitrile

TOFACITINIB IMPURITY 51
Formula: C21H27N7O3
425.49
RM-T060489
ethyl 2-cyano-3-imino-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopentanoate

TOFACITINIB IMPURITY 52
Formula: C25H33N9O2
491.6
RM-T060490
(3R,4R)-3-((2-(((3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl)(methyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidine-1-carbonyl cyanide

TOFACITINIB IMPURITY 53
CAS:1527525-58-1
Formula: C15H18N6O
298.35
RM-T060491
3-((3R,4R)-3-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

TOFACITINIB IMPURITY 54
Formula: C20H25N5*2
335.46*2
RM-T060492
N-((3R,4S)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine--N-((3S,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine (1/1)

TOFACITINIB IMPURITY 55
Formula: C26H35N5O
433.6
RM-T060493
4-(4-(((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)(methyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-4-methylpentan-2-one

TOFACITINIB IMPURITY 57
Formula: C16H20N6O
312.38
RM-T060495
3-((3S,4S)-4-methyl-3-(methyl(5H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

TOFACITINIB IMPURITY 58
Formula: C14H20N6O
288.36
RM-T060496
3-((3S,4S)-3-((6-aminopyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

TOFACITINIB IMPURITY 59
Formula: C16H20N6O2
328.38
RM-T060497
3-((3S,4S)-3-((7-hydroxy-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

TOFACITINIB IMPURITY 60
CAS:1269823-96-2
Formula: C16H20N6O2
328.38
RM-T060498
3-(4-methyl-3-(methyl(6-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

TOFACITINIB IMPURITY 61
CAS:923036-28-6
Formula: C15H20N2O2
260.34
RM-T060499
methyl (1-benzyl-4-methyl-1,2,5,6-tetrahydropyridin-3-yl)carbamate

TOFACITINIB IMPURITY 63
CAS:1354621-59-2
Formula: C14H22N2
218.34
RM-T060363
(3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine

TOFACITINIB IMPURITY 64
CAS:2026634-40-0
Formula: C13H20N2
204.31
RM-T060364
(3R,4R)-1-benzyl-4-methylpiperidin-3-amine

TOFACITINIB IMPURITY 65
Formula: C6H4ClN3O
169.57
RM-T060365
2-chlorofuro[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY 66
CAS:10132-07-7
Formula: C4H3Cl2N3
163.99
RM-T060366
2,6-Dichloropyrimidin-4-amine

TOFACITINIB IMPURITY 67
CAS:2459302-87-3
Formula: C26H26Cl2N8
521.44
RM-T060367
N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-2,2'-dichloro-N-methyl-7H-[4,7'-bipyrrolo[2,3-d]pyrimidin]-4'-amine

TOFACITINIB IMPURITY 68
CAS:1616761-00-2
Formula: C16H19ClN6O
346.81
RM-T060368
3-((3R,4R)-3-((2-Chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

TOFACITINIB IMPURITY 69
CAS:2227197-38-6
Formula: C14H21N5
259.35
RM-T060369
N-((3R,4R)-1,4-dimethylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY 70
Formula: C14H22N2O
234.34
RM-T060370
N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methylhydroxylamine

Tofacitinib Impurity 71
Formula: C14H22N2O
234.34
RM-T060371
(3R,4R)-1-benzyl-4-methyl-3-(methylamino)piperidine 1-oxide

TOFACITINIB IMPURITY 72
CAS:2374700-40-8
Formula: C16H20N6O
312.37
RM-T060372
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

Tofacitinib Impurity 73
CAS:1616760-97-4
Formula: C13H18ClN5
279.77
RM-T060373
2-chloro-N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 74
CAS:1260614-73-0
Formula: C13H19N5
245.32
RM-T060374
N-methyl-N-((3s,4s)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY 75
Formula: C6H5N3O2
151.12
RM-T060375
7H-Pyrrolo[2,3-d]pyrimidine-2,4-diol

TOFACITINIB IMPURITY 76
Formula: C15H21N5O
287.36
RM-T060376
3-((3R,4R)-3-((4-aminopyridin-2-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

TOFACITINIB IMPURITY 77
CAS:1640971-51-2
Formula: C16H20N6O2
328.37
RM-T060377
3-((3R,4R)-4-methyl-3-(methyl(6-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

TOFACITINIB IMPURITY 78
Formula: C32H40N12O2
624.74
RM-T060378
3-hydroxy-3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-2-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carbonyl)pentanedinitrile

Tofacitinib Impurity 79
Formula: C34H45N7
551.77
RM-T060379
N2,N4-bis((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N2,N4-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine

Tofacitinib Impurity 80
CAS:271-70-5
Formula: C6H5N3
119.12
RM-T060380
7H-Pyrrolo[2,3-d]pyrimidine

TOFACITINIB IMPURITY 81
Formula: C13H19N5O
261.32
RM-T060381
(3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-ol

Tofacitinib Impurity 82
CAS:2268720-86-9
Formula: C20H24ClN5
369.89
RM-T060382
N-(1-benzyl-4-methylpiperidin-3-yl)-2-chloro-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY 83
Formula: C13H19N5
245.32
RM-T060383
N-methyl-N-((3R,4S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine--N-methyl-N-((3S,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (1/1)

Tofacitinib Impurity 84
CAS:3680-69-1
Formula: C6H4ClN3
153.57
RM-T060384
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine

TOFACITINIB IMPURITY 85
CAS:2459302-75-9
Formula: C13H19N5
245.32
RM-T060385
N-methyl-N-((3R,4S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 86
Formula: C13H19N5
245.32
RM-T060386
N-methyl-N-((3S,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 87
Formula: C13H18N4O2
262.31
RM-T060387
2-cyano-N-((3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl)-N-methylacetamide

TOFACITINIB IMPURITY 88
CAS:1206875-41-3(free base)
Formula: C15H23ClN2O2
298.81
RM-T060388
methyl (1-benzyl-4-methylpiperidin-3-yl)carbamate hydrochloride

Tofacitinib Impurity 89
CAS:2504210-51-7
Formula: C26H28N8
452.55
RM-T060389
N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-[4,7'-bipyrrolo[2,3-d]pyrimidin]-4'-amine

TOFACITINIB IMPURITY 90
CAS:1675248-18-6
Formula: C18H25N5O3
359.42
RM-T060390
ethyl 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoate

TOFACITINIB IMPURITY 91
CAS:16372-08-0
Formula: C6H6ClN3
155.58
RM-T060391
4-chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine

Tofacitinib Impurity 92
Formula: C33H34N8O4S2
670.8
RM-T060392
N-methyl-N-((3R,4R)-4-methyl-1-(7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl)-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Tofacitinib Impurity 93
CAS:1616761-01-3
Formula: C17H23N5O3
345.4
RM-T060393
methyl 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoate

TOFACITINIB IMPURITY 94
CAS:77862-24-9
Formula: C7H10N2
122.17
RM-T060394
N,4-dimethylpyridin-3-amine

Tofacitinib Impurity 95
Formula: C20H25N5
335.45
RM-T060395
N-(1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY 96
CAS:52090-68-3
Formula: C8H10N2O
150.18
RM-T060396
N-(4-methylpyridin-3-yl)acetamide

TOFACITINIB IMPURITY 97
CAS:1638499-35-0
Formula: C15H17ClN2O
276.76
RM-T060397
3-acetamido-1-benzyl-4-methylpyridin-1-ium chloride

Tofacitinib Impurity 98
CAS:32018-96-5
Formula: C13H17NO
203.28
RM-T060398
1-benzyl-4-methylpiperidin-3-one

Tofacitinib Impurity 99
Formula: C15H20N2O
244.33
RM-T060399
N-(1-benzyl-4-methyl-1,2,5,6-tetrahydropyridin-3-yl)acetamide

TOFACITINIB IMPURITY A
Formula: C27H31N5O2S
489.63
RM-T060301
N-((3R,4S)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY B
Formula: C27H31N5O2S
489.63
RM-T060302
N-((3S,4S)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY C
Formula: C27H31N5O2S
489.63
RM-T060303
N-((3S,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY D
CAS:479633-63-1
Formula: C13H10ClN3O2S
307.76
RM-T060304
4-Chloro-7-tosyl-7h-pyrrolo[2,3-d]pyrimidine

TOFACITINIB IMPURITY E
CAS:923036-30-0
Formula: C27H31N5O2S
489.63
RM-T060305
N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY F
CAS:1702274-61-0(X HCl)
Formula: C20H25N5
335.45
RM-T060306
N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY I
Formula: C13H19N5
245.32
RM-T060309
N-methyl-N-((3S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY K
Formula: C16H20N6O
312.37
RM-T060311
3-((3S)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

TOFACITINIB IMPURITY M
CAS:477600-74-1
Formula: C13H19N5
245.33
RM-T060360
N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY O
CAS:1092578-46-5
Formula: C16H20N6O
312.37
RM-T060315
3-((3R,4S)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

TOFACITINIB IMPURITY P
CAS:1092578-48-7
Formula: C16H20N6O
312.37
RM-T060316
3-((3S,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

TOFACITINIB IMPURITY Q
CAS:1092578-47-6
Formula: C16H20N6O
312.38
RM-T060346
3-((3S,4S)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

TOFACITINIB IMPURITY R
CAS:477600-76-3
Formula: C15H21N5O
287.36
RM-T060318
1-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)ethanone

TOFACITINIB IMPURITY S
CAS:2328165-36-0
Formula: C16H21N5O3
331.37
RM-T060319
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoic acid/3-((3R,4R)-4-methyl-3-(methyl(3H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoic acid

TOFACITINIB IMPURITY T
CAS:1675248-19-7
Formula: C16H22N6O2
330.38
RM-T060320
3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanamide

TOFACITINIB IMPURITY U
Formula: C15H21N3
243.35
RM-T060321
N-methyl-N-((3R,4S)-4-methylpiperidin-3-yl)-1H-indol-4-amine

TOFACITINIB IMPURITY V
Formula: C15H21N3
243.35
RM-T060322
N-methyl-N-((3S,4R)-4-methylpiperidin-3-yl)-1H-indol-4-amine

TOFACITINIB IMPURITY W
Formula: C15H21N3O
259.35
RM-T060323
(3S,4S)-3-((1H-indol-4-yl)(methyl)amino)-4-methylpiperidin-1-ol

TOFACITINIB IMPURITY X
CAS:1252883-90-1
Formula: C20H25N5
335.45
RM-T060324
N-((3S,4S)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY Y
Formula: C20H25N5
335.45
RM-T060325
N-((3R,4S)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB IMPURITY Z
Formula: C20H25N5
335.45
RM-T060326
N-((3S,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

TOFACITINIB RELATED IMPURITY 1
CAS:1354469-76-3
Formula: C7H16N2
128.22
RM-T060327
(3R,4R)-N,4-Dimethylpiperidin-3-amine

TOFACITINIB RELATED IMPURITY 10
CAS:1821769-41-8
Formula: C14H22N2*2HCl
291.26
RM-T060336
(3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride

TOFACITINIB RELATED IMPURITY 2
CAS:3430-27-1
Formula: C6H8N2
108.14
RM-T060328
3-Amino-4-methylpyridine

TOFACITINIB RELATED IMPURITY 3
CAS:694495-63-1
Formula: C8H10N2O2
166.18
RM-T060329
Methyl N-(4-methylpyridin-3-yl)carbamate

TOFACITINIB RELATED IMPURITY 4
Formula: C8H16N2O2
172.22
RM-T060330
methyl ((3R,4R)-4-methylpiperidin-3-yl)carbamate

TOFACITINIB RELATED IMPURITY 5
Formula: C15H22N2O2
262.35
RM-T060331
methyl ((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)carbamate

TOFACITINIB RELATED IMPURITY 6
CAS:384338-23-2
Formula: C14H22N2
218.34
RM-T060332
1-benzyl-N,4-dimethylpiperidin-3-amine

Tofacitinib Related Impurity 7
CAS:477600-70-7
Formula: C14H22N2
218.34
RM-T060333
(3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine

Tofacitinib Related Impurity 9
CAS:1638499-31-6
Formula: C14H22N2
218.34
RM-T060335
(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine

TOFACITINIB-D3 CITRATE
Formula: C16H17D3N6O
315.4
RM-T060442
3-((3R,4R)-4-methyl-3-((methyl-d3)(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

TOLBUTAMIDE
CAS:64-77-7
Formula: C12H18N2O3S
270.35
RM-T151300
N-(butylcarbamoyl)-4-methylbenzenesulfonamide

Tolbutamide EP Impurity B; Gliclazide Impurity 11
CAS:1694-06-0
Formula: C8H10N2O3S
214.24
RM-T151302
N-carbamoyl-4-methylbenzenesulfonamide

Tolbutamide EP Impurity C
Formula: C14H21N3O3S
311.4
RM-T151303
N-(azepan-1-ylcarbamoyl)-4-methylbenzenesulfonamide

TOLBUTAMIDE IMPURITY 4
CAS:5719-85-7
Formula: C12H18N2O4S
286.35
RM-T151304
N-(butylcarbamoyl)-4-(hydroxymethyl)benzenesulfonamide

TOLCAPONE
CAS:134308-13-7
Formula: C14H11NO5
273.24
RM-T450000
(3,4-dihydroxy-5-nitrophenyl)(p-tolyl)methanone

TOLCAPONE IMPURITY 1
CAS:134612-80-9
Formula: C15H13NO5
287.27
RM-T450001
(4-Hydroxy-3-methoxy-5-nitrophenyl)(p-tolyl)methanone

TOLCLOFOS-METHYL
CAS:57018-04-9
Formula: C9H11Cl2O3PS
301.13
RM-T120800
O-(2,6-Dichloro-4-methylphenyl) O,O-dimethyl phosphorothioate

TOLFENAMIC ACID
CAS:13710-19-5
Formula: C14H12ClNO2
261.7
RM-T151400
2-((3-chloro-2-methylphenyl)amino)benzoic acid

TOLFENAMIC ACID EP IMPURITY B
CAS:87-60-5
Formula: C7H8ClN
141.6
RM-T151402
3-Chloro-2-methylaniline

TOLFENAMIC ACID EP IMPURITY C
Formula: C14H10ClNO
243.69
RM-T151403
3-chloro-4-methylacridin-9(10H)-one

TOLFENPYRAD
CAS:129558-76-5
Formula: C21H22ClN3O2
383.87
RG-A260516
TOLFENPYRAD

TOLNAFTATE
CAS:2398-96-1
Formula: C19H17NOS
307.41
RM-T151500
O-naphthalen-2-yl methyl(m-tolyl)carbamothioate

TOLNAFTATE EP IMPURITY B
Formula: C21H14O2S
330.4
RM-T151502
O,O-di(naphthalen-2-yl) carbonothioate

TOLNAFTATE EP IMPURITY D
Formula: C8H11N
121.18
RM-T151504
N,3-Dimethylaniline

TOLNAFTATE IMPURITY 5
CAS:842-07-9
Formula: C16H12N2O
248.28
RM-T151505
Sudan Yellow; 1-(phenyldiazenyl)naphthalen-2-ol

Tolnaftate Impurity 6
CAS:3118-97-6
Formula: C18H16N2O
276.34
RM-T151506
Sudan Red; 1-((2,4-dimethylphenyl)diazenyl)naphthalen-2-ol

TOLPERISONE IMPURITY 1
CAS:5337-93-9
Formula: C10H12O
148.2
RM-T150501
1-(p-tolyl)propan-1-one

Tolperisone Impurity 10
Formula: C16H23NO2
261.37
RM-T150510
1-(4-(hydroxymethyl)phenyl)-2-methyl-3-(piperidin-1-yl)propan-1-one

TOLPERISONE IMPURITY 2
CAS:158176-60-4
Formula: C16H23NO
245.37
RM-T150502
2-methyl-3-(piperidin-1-yl)-1-(o-tolyl)propan-1-one

TOLPERISONE IMPURITY 3
CAS:756433-31-5
Formula: C16H23NO
245.36
RM-T150503
2-methyl-3-(piperidin-1-yl)-1-(m-tolyl)propan-1-one

TOLPERISONE IMPURITY 4
CAS:1023-20-7
Formula: C15H21NO HCl
231.33 36.46
RM-T150504
3-(piperidin-1-yl)-1-(p-tolyl)propan-1-one hydrochloride

TOLPERISONE IMPURITY 5
CAS:62834-89-3
Formula: C11H12O
160.21
RM-T150505
2-methyl-1-(p-tolyl)prop-2-en-1-one

TOLPERISONE IMPURITY 6
Formula: C16H23NO2
261.36
RM-T150506
1-(2-methyl-3-oxo-3-(p-tolyl)propyl)piperidine 1-oxide

TOLPERISONE IMPURITY 7
Formula: C13H16O2
204.26
RM-T150507
1,1'-(4-methyl-1,3-phenylene)bis(propan-1-one)

Tolperisone Impurity 8
CAS:2040-14-4
Formula: C10H12O
148.21
RM-T150508
1-(o-tolyl)propan-1-one

Tolperisone Impurity 9
CAS:51772-30-6
Formula: C10H12O
148.21
RM-T150509
1-(m-tolyl)propan-1-one

TOLTERODINE
CAS:124937-51-5
Formula: C22H31NO
325.49
RM-T201800
(R)-2-(3-(diisopropylamino)-1-phenylpropyl)-4-methylphenol

TOLTERODINE 5-HYDROXYMETHYL ANALOG RACEMATE
CAS:200801-70-3
Formula: C22H31NO2
341.49
RM-T201808
N,N-Diisopropyl-3-(2-hydroxy-5-hydroxymethylphenyl)-3-phenylpropan-1-amine

TOLTERODINE ACID
Formula: C16H16O3
256.3
RM-T201802
3-(2-Hydroxy-5-methylphenyl)-3-phenylpropanoic acid

TOLTERODINE EP IMPURITY A
CAS:124937-73-1
Formula: C17H20O2
256.34
RM-T201803
3-Phenyl-3-(2-methoxy-5-methylphenyl)propanol

TOLTERODINE EP IMPURITY C
CAS:124935-89-3
Formula: C27H37NO5
455.59
RM-T201801
N,N-Diisopropyl-3-(2-methoxy-5-methylphenyl)-3-phenylpropan-1-amine fumarate

Tolterodine EP Impurity D
CAS:1391053-65-8
Formula: C20H27NO
297.44
RM-T201806
N-isopropyl-3-(2-methoxy-5-methylphenyl)-3-phenylpropan-1-amine

TOLTERODINE EP IMPURITY E
CAS:480432-14-2
Formula: C19H25NO
283.42
RM-T201805
2-(3-(isopropylamino)-1-phenylpropyl)-4-methylphenol

TOLTERODINE EP IMPURITY F
CAS:124937-53-7
Formula: C22H31NO
325.49
RM-T201811
(S)-2-(3-(diisopropylamino)-1-phenylpropyl)-4-methylphenol

TOLTERODINE EP IMPURITY G
CAS:1554029-91-2
Formula: C22H31NO2
341.49
RM-T201813
3-(2-hydroxy-5-methylphenyl)-N,N-diisopropyl-3-phenylpropan-1-amine oxide

TOLTERODINE IMPURITY 14
Formula: C21H29NO HCl
311.46 36.46
RM-T201814
2-(3-(diisopropylamino)-1-phenylpropyl)phenol hydrochloride

TOLTERODINE IMPURITY 15
CAS:851789-43-0
Formula: C16H18O2
242.31
RM-T201815
2-(3-Hydroxy-1-phenylpropyl)-4-methylphenol

TOLTERODINE IMPURITY 16
CAS:209747-04-6
Formula: C16H16O2
240.3
RM-T201816
6-Methyl-4-phenylchroman-2-ol

TOLTERODINE IMPURITY 17
Formula: C18H20O3
284.35
RM-T201817
3-(2-Hydroxy-5-methylphenyl)-3-phenylpropyl acetate

Tolterodine Impurity 18
CAS:40546-94-9
Formula: C16H14O2
238.28
RM-T201818
6-Methyl-4-phenylchroman-2-one

TOLTERODINE IMPURITY 19
CAS:194482-41-2(free base)
Formula: C19H25NO HCl
283.41 36.46
RM-T201819
(R)-2-(3-(isopropylamino)-1-phenylpropyl)-4-methylphenol hydrochloride

TOLTERODINE IMPURITY 20
CAS:848768-06-9
Formula: C29H37NO
415.61
RM-T201820
(R)-3-(2-(benzyloxy)-5-methylphenyl)-N,N-diisopropyl-3-phenylpropan-1-amine

TOLTERODINE IMPURITY 21
CAS:260389-90-0
Formula: C22H31NO2
341.49
RM-T201821
(S)-2-(3-(diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenol

TOLTERODINE IMPURITY 22
CAS:906532-18-1
Formula: C22H31NO
325.49
RM-T201822
N,N-diisopropyl-3-phenyl-3-(p-tolyloxy)propan-1-amine

TOLTERODINE IMPURITY 23
CAS:173948-30-6
Formula: C15H23N
217.35
RM-T201823
(E)-N,N-Diisopropyl-3-phenylprop-2-en-1-amine

TOLTERODINE IMPURITY 24
CAS:156755-37-2
Formula: C29H37NO2
431.61
RM-T201824
(R)-(4-(benzyloxy)-3-(3-(diisopropylamino)-1-phenylpropyl)phenyl)methanol

TOLTERODINE IMPURITY 25
CAS:1076199-77-3
Formula: C22H29NO3
355.47
RM-T201825
3-(3-(diisopropylamino)-1-phenylpropyl)-4-hydroxybenzoic acid

TOLTERODINE IMPURITY 26
CAS:210573-52-7
Formula: C28H39NO8
517.61
RM-T201826
(2S,3S,4S,5R,6S)-6-(2-((R)-3-(diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

Tolterodine Impurity 27
CAS:124936-82-9
Formula: C22H31NO
325.5
RM-T201827
2-(3-(diisopropylamino)-1-phenylpropyl)-5-methylphenol

Tolterodine Impurity 28
Formula: C16H19NO
241.33
RM-T201828
(S)-2-(3-amino-1-phenylpropyl)-4-methylphenol

Tolterodine Impurity 29
CAS:828933-86-4
Formula: C16H16O2
240.3
RM-T201829
(4R)-6-methyl-4-phenylchroman-2-ol

Tolterodine Impurity 31
Formula: C16H19NO
241.33
RM-T201831
2-(3-Amino-1-phenylpropyl)-4-methylphenol

Tolterodine Impurity 32
Formula: C17H18O3
270.33
RM-T201832
3-(2-methoxy-5-methylphenyl)-3-phenylpropanoic acid

Tolterodine Impurity 33
CAS:124935-88-2
Formula: C23H33NO
339.52
RM-T201833
N,N-Diisopropyl-3-(2-methoxy-5-methylphenyl)-3-phenylpropan-1-amine

Tolterodine Impurity 34
CAS:1380491-70-2
Formula: C26H37NO3
411.59
RM-T201834
(R)-3-(3-(diisopropylamino)-1-phenylpropyl)-4-hydroxybenzyl isobutyrate

Tolterodine Impurity 35
Formula: C16H14O2
238.29
RM-T201835
7-methyl-4-phenylchroman-2-one

Tolterodine Impurity 36
Formula: C18H20O3
284.36
RM-T201836
methyl 3-(2-methoxy-4-methylphenyl)-3-phenylpropanoate

Tolterodine Impurity 38
Formula: C17H20O2
256.35
RM-T201838
3-(2-methoxy-4-methylphenyl)-3-phenylpropan-1-ol

Tolterodine Impurity 39
Formula: C23H33NO
339.52
RM-T201839
N,N-diisopropyl-3-(2-methoxy-4-methylphenyl)-3-phenylpropan-1-amine

TOLTERODINE IMPURITY 4
Formula: C22H31NO
325.5
RM-T201804
2-(3-(diisopropylamino)-1-phenylpropyl)-4-methylphenol

Tolterodine Impurity 40
CAS:851789-51-0
Formula: C16H18O2
242.32
RM-T201840
(R)-2-(3-hydroxy-1-phenylpropyl)-4-methylphenol

Tolterodine Impurity 41
Formula: C16H18O2
242.32
RM-T201841
(S)-2-(3-hydroxy-1-phenylpropyl)-4-methylphenol

Tolterodine Impurity 42
Formula: C24H24O3
360.45
RM-T201842
Methyl 3-(2-(benzyloxy)-5-methylphenyl)-3-phenylpropanoate

Tolterodine Impurity 43
Formula: C25H26O3
374.48
RM-T201843
3-(2-(benzyloxy)-5-methylphenyl)-3-phenylpropyl acetate

Tolterodine Impurity 44
Formula: C23H24O2
332.44
RM-T201844
3-(2-(Benzyloxy)-5-methylphenyl)-3-phenylpropan-1-ol

Tolterodine Impurity J
CAS:854306-72-2
Formula: C35H41NO2
507.71
RM-T201810
2,2'-((isopropylazanediyl)bis(1-phenylpropane-3,1-diyl))bis(4-methylphenol)

Tolterodine Impurity L
Formula: C29H37NO
415.61
RM-T201812
3-(2-(benzyloxy)-5-methylphenyl)-N,N-diisopropyl-3-phenylpropan-1-amine

TOLTERODINE-D14
CAS:1191280-43-9
Formula: C22H17D14NO
339.58
RM-T201830
(R)-2-(3-(bis(propan-2-yl-d7)amino)-1-phenylpropyl)-4-methylphenol

TOLTRAZURIL
CAS:69004-03-1
Formula: C18H14F3N3O4S
425.38
RG-A260864
Toltrazuril

TOLTRAZURIL SULFONE (PONAZURIL)
CAS:69004-04-2
Formula: C18H14F3N3O6S
457.38
RM-T385001
1-methyl-3-(3-methyl-4-(4-((trifluoromethyl)sulfonyl)phenoxy)phenyl)-1,3,5-triazinane-2,4,6-trione

Toluene-4-Sulfonic Acid; Anastrozole EP Impurity F; Tizanidine EP Impurity I; Sultamicillin EP Impurity B; Lisinopril EP Impurity B; Escitalopram EP Impurity J
CAS:104-15-4
Formula: C7H8O3S
172.2
RG-T121401
4-Methylbenzenesulfonic Acid

TOLVAPTAN
CAS:150683-30-0
Formula: C26H25ClN2O3
448.94
RM-T151200
N-(4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

Tolvaptan Dimer Impurity 102
Formula: C52H49ClN4O6
861.44
RM-T152302
N-(4-(7-((7-chloro-1-(2-methyl-4-(2-methylbenzamido)benzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl)oxy)-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

Tolvaptan Dimer Impurity 99
Formula: C52H48Cl2N4O5
879.88
RM-T151299
N,N'-((5,5'-oxybis(7-chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepine-5,1-diyl-1-carbonyl))bis(3-methyl-4,1-phenylene))bis(2-methylbenzamide)

TOLVAPTAN IMPURITY 1
CAS:150683-27-5
Formula: C25H23ClN2O3
434.91
RM-T151201
N-(4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-2-methylbenzamide

TOLVAPTAN IMPURITY 10
CAS:1432725-23-9
Formula: C26H26N2O3
414.5
RM-T151210
N-(4-(5-Hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

Tolvaptan Impurity 101
CAS:1448365-49-8
Formula: C19H18ClNO5S
407.87
RM-T151301
methyl 7-chloro-5-oxo-1-tosyl-2,3,4,5-tetrahydro-1H-benzo[b]azepine-4-carboxylate

Tolvaptan Impurity 103
Formula: C27H27ClN2O3
462.97
RM-T152303
N-(4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2,3-dimethylbenzamide

Tolvaptan Impurity 104
CAS:1859917-54-6
Formula: C27H28N2O4
444.53
RM-T152304
N-(4-(5-hydroxy-7-methoxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

Tolvaptan Impurity 105
Formula: C34H29ClN2O4
565.07
RM-T152305
N-(4-(7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methyl-N-(2-methylbenzoyl)benzamide

Tolvaptan Impurity 106
Formula: C42H35ClN2O5
683.2
RM-T152306
7-chloro-1-(2-methyl-4-(2-methyl-N-(2-methylbenzoyl)benzamido)benzoyl)-2,3-dihydro-1H-benzo[b]azepin-5-yl 2-methylbenzoate

Tolvaptan Impurity 107
CAS:1580889-23-1
Formula: C34H31ClN2O4
567.08
RM-T152307
7-chloro-1-(2-methyl-4-(2-methylbenzamido)benzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl 2-methylbenzoate

Tolvaptan Impurity 108
Formula: C26H26ClN2O5P
512.93
RM-T152308
7-chloro-1-(2-methyl-4-(2-methylbenzamido)benzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl hydrogen phosphonate

TOLVAPTAN IMPURITY 11
CAS:1127-74-8
Formula: C10H11NO
161.2
RM-T151211
3,4-dihydro-1H-benzo[b]azepin-5(2H)-one

TOLVAPTAN IMPURITY 12
Formula: C26H25BrN2O3
493.4
RM-T151212
N-(4-(7-bromo-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

TOLVAPTAN IMPURITY 13
CAS:1310357-40-4
Formula: C10H12ClNO
197.66
RM-T151213
7-chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-ol

TOLVAPTAN IMPURITY 14
CAS:317374-08-6
Formula: C16H15NO3
269.3
RM-T151214
2-methyl-4-(2-methylbenzamido)benzoic acid

TOLVAPTAN IMPURITY 15
CAS:2486-75-1
Formula: C8H9NO2
151.17
RM-T151215
4-Amino-2-methylbenzoic acid

TOLVAPTAN IMPURITY 16
CAS:1587638-05-8
Formula: C26H25ClN2O4
464.95
RM-T151216
N-(4-(7-chloro-4,5-dihydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

TOLVAPTAN IMPURITY 17
CAS:2657689-28-4
Formula: C42H38ClN3O5
700.23
RM-T151217
N-(4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methyl-4-(2-methylbenzamido)-N-(2-methylbenzoyl)benzamide

TOLVAPTAN IMPURITY 18
CAS:2458812-60-5
Formula: C34H32ClN3O4
582.1
RM-T151218
N-(4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methyl-4-(2-methylbenzamido)benzamide

TOLVAPTAN IMPURITY 19
CAS:1580889-36-6
Formula: C42H36ClN3O5
698.22
RM-T151219
7-chloro-1-(2-methyl-4-(2-methylbenzamido)benzoyl)-2,3-dihydro-1H-benzo[b]azepin-5-yl 2-methyl-4-(2-methylbenzamido)benzoate

TOLVAPTAN IMPURITY 2
Formula: C11H14ClNO
211.69
RM-T151202
7-chloro-4-methoxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine

TOLVAPTAN IMPURITY 20
Formula: C16H15NO3
269.3
RM-T151220
2-methyl-4-(3-methylbenzamido)benzoic acid

TOLVAPTAN IMPURITY 21
CAS:1580889-26-4
Formula: C26H23ClN2O3
446.93
RM-T151221
N-(4-(7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-3-methylbenzamide

TOLVAPTAN IMPURITY 22
Formula: C15H13NO3
255.27
RM-T151222
4-benzamido-2-methylbenzoic acid

TOLVAPTAN IMPURITY 23
Formula: C25H21ClN2O3
432.9
RM-T151223
N-(4-(7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)benzamide

TOLVAPTAN IMPURITY 25
CAS:2657689-30-8
Formula: C32H28N2O5
520.59
RM-T151225
2-methyl-4-(2-methyl-4-(2-methylbenzamido)-N-(2-methylbenzoyl)benzamido)benzoic acid

TOLVAPTAN IMPURITY 26
CAS:2657689-34-2
Formula: C42H36ClN3O5
698.22
RM-T151226
N-(4-(7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methyl-4-(2-methylbenzamido)-N-(2-methylbenzoyl)benzamide

TOLVAPTAN IMPURITY 27
CAS:160129-45-3
Formula: C10H10ClNO
195.65
RM-T151227
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one

TOLVAPTAN IMPURITY 28
CAS:1859917-22-8
Formula: C18H17ClN2O
312.8
RM-T151228
(4-amino-2-methylphenyl)(7-chloro-2,3-dihydro-1H-benzo[b]azepin-1-yl)methanone

TOLVAPTAN IMPURITY 29
CAS:4277-00-3
Formula: C8H6N2O6
226.14
RM-T151229
2-methyl-4,6-dinitrobenzoic acid

TOLVAPTAN IMPURITY 3
Formula: C30H33ClN2O4
521.05
RM-T151203
N-(4-(7-chloro-5,5-diethoxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

TOLVAPTAN IMPURITY 30
CAS:193686-76-9
Formula: C17H16ClNO3S
349.83
RM-T151230
7-chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one

TOLVAPTAN IMPURITY 31
CAS:247237-56-5
Formula: C10H10ClNO
195.65
RM-T151231
9-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one

TOLVAPTAN IMPURITY 32
CAS:792931-76-1
Formula: C13H14ClNO3
267.71
RM-T151232
ethyl 7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-4-carboxylate

TOLVAPTAN IMPURITY 33
CAS:1711-06-4
Formula: C8H7ClO
154.59
RM-T151233
3-Methylbenzoyl Chloride

TOLVAPTAN IMPURITY 34
CAS:1975-51-5
Formula: C8H7NO4
181.15
RM-T151234
2-Methyl-4-nitrobenzoic acid

TOLVAPTAN IMPURITY 35
Formula: C32H28N2O5
520.59
RM-T151235
2-methyl-4-(2-methyl-N-(2-methyl-4-(2-methylbenzamido)benzoyl)benzamido)benzoic acid

TOLVAPTAN IMPURITY 36
CAS:30459-70-2
Formula: C8H6ClNO3
199.59
RM-T151236
2-methyl-4-nitrobenzoyl chloride

TOLVAPTAN IMPURITY 37
CAS:176970-21-1
Formula: C26H23ClN2O2
430.93
RM-T151237
N-(4-(7-chloro-2,3-dihydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

TOLVAPTAN IMPURITY 38
Formula: C18H15BrN2O4
403.23
RM-T151238
7-bromo-1-(2-methyl-4-nitrobenzoyl)-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one

TOLVAPTAN IMPURITY 39
Formula: C18H17ClN2O3
344.8
RM-T151239
7-chloro-1-(4-(hydroxyamino)-2-methylbenzoyl)-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one

TOLVAPTAN IMPURITY 4
CAS:1432725-24-0
Formula: C18H19ClN2O2
330.81
RM-T151204
(4-amino-2-methylphenyl)(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)methanone

TOLVAPTAN IMPURITY 40
Formula: C36H34Cl2N4O3
641.59
RM-T151240
1-(4-((1-(4-amino-2-methylbenzoyl)-7-chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl)amino)-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one

TOLVAPTAN IMPURITY 41
CAS:1580889-24-2
Formula: C26H23ClN2O3
446.93
RM-T151241
N-(4-(7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-4-methylbenzamide

TOLVAPTAN IMPURITY 42
CAS:1580889-27-5
Formula: C26H25ClN2O3
448.95
RM-T151242
N-(4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-3-methylbenzamide

TOLVAPTAN IMPURITY 43
CAS:1346599-56-1
Formula: C26H23ClN2O5
478.93
RM-T151243
4-(5-chloro-2-(2-methyl-4-(2-methylbenzamido)benzamido)phenyl)-4-oxobutanoic acid

TOLVAPTAN IMPURITY 44
Formula: C26H25ClN2O5
480.95
RM-T151244
4-(5-chloro-2-(2-methyl-4-(2-methylbenzamido)benzamido)phenyl)-4-hydroxybutanoic acid

TOLVAPTAN IMPURITY 45
Formula: C26H27ClN2O4
466.96
RM-T151245
N-(4-chloro-2-(1,4-dihydroxybutyl)phenyl)-2-methyl-4-(2-methylbenzamido)benzamide

TOLVAPTAN IMPURITY 46
CAS:1133419-00-7
Formula: C20H20ClNO5S
421.89
RM-T151246
ethyl 7-chloro-5-oxo-1-tosyl-2,3,4,5-tetrahydro-1H-benzo[b]azepine-4-carboxylate

TOLVAPTAN IMPURITY 47
CAS:942619-74-1
Formula: C26H26ClN2O6P
528.93
RM-T151247
7-chloro-1-(2-methyl-4-(2-methylbenzamido)benzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl dihydrogen phosphate

TOLVAPTAN IMPURITY 48
CAS:6933-47-7
Formula: C9H11NO2
165.19
RM-T151248
Methyl 4-amino-2-methylbenzoate

TOLVAPTAN IMPURITY 49
CAS:74450-59-2
Formula: C10H13NO2
179.22
RM-T151249
Ethyl 4-amino-2-methylbenzoate

TOLVAPTAN IMPURITY 5
CAS:137977-97-0
Formula: C18H17ClN2O2
328.79
RM-T151205
1-(4-Amino-2-methylbenzoyl)-7-chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one

TOLVAPTAN IMPURITY 50
CAS:5202-89-1
Formula: C8H8ClNO2
185.61
RM-T151250
Methyl 2-amino-5-chlorobenzoate

TOLVAPTAN IMPURITY 51
CAS:247237-38-3
Formula: C15H14ClNO4S
339.79
RM-T151251
methyl 5-chloro-2-((4-methylphenyl)sulfonamido)benzoate

TOLVAPTAN IMPURITY 52
CAS:247237-43-0
Formula: C21H24ClNO6S
453.93
RM-T151252
methyl 5-chloro-2-((N-(4-ethoxy-4-oxobutyl)-4-methylphenyl)sulfonamido)benzoate

TOLVAPTAN IMPURITY 53
Formula: C26H27ClN2O9P2
608.9
RM-T151253
7-chloro-1-(2-methyl-4-(2-methylbenzamido)benzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl trihydrogen diphosphate

TOLVAPTAN IMPURITY 54
CAS:150683-52-6
Formula: C27H27ClN2O3
462.97
RM-T151254
N-(4-(7-chloro-5-methoxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

TOLVAPTAN IMPURITY 55
Formula: C27H27ClN2O4
478.97
RM-T151255
N-(4-(7-chloro-5-hydroxy-5-methoxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

TOLVAPTAN IMPURITY 56
Formula: C10H11ClN2O2
226.66
RM-T151256
7-chloro-1-nitroso-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-ol

TOLVAPTAN IMPURITY 57
Formula: C18H16ClNO2
313.78
RM-T151257
7-chloro-1-(2-methylbenzoyl)-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one

Tolvaptan Impurity 58
Formula: C16H16N2O3
284.32
RM-T151258
4-(4-amino-2-methylbenzamido)-2-methylbenzoic acid

Tolvaptan Impurity 59
CAS:137982-91-3
Formula: C18H15ClN2O4
358.78
RM-T151259
7-chloro-1-(2-methyl-4-nitrobenzoyl)-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one

TOLVAPTAN IMPURITY 6
Formula: C25H24N2O3
400.47
RM-T151206
N-(4-(5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-2-methylbenzamide

Tolvaptan Impurity 60
Formula: C18H18ClNO2
315.8
RM-T151260
(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)(o-tolyl)methanone

Tolvaptan Impurity 61
Formula: C26H26N2O3
414.51
RM-T151261
N-(4-(5-Hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-4-methylbenzamide

Tolvaptan Impurity 62
Formula: C27H26N2O3
426.52
RM-T151262
N-(4-(5-methoxy-2,3-dihydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

Tolvaptan Impurity 63
Formula: C42H38ClN3O5
700.23
RM-T151263
7-chloro-1-(2-methyl-4-(2-methylbenzamido)benzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl 2-methyl-4-(2-methylbenzamido)benzoate

Tolvaptan Impurity 64
Formula: C18H17ClN2O4
360.79
RM-T151264
(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)(2-methyl-4-nitrophenyl)methanone

Tolvaptan Impurity 65
Formula: C26H23ClN2O4
462.93
RM-T151265
7-chloro-1-(4-(hydroxyamino)-2-methylbenzoyl)-2,3-dihydro-1H-benzo[b]azepin-5-yl 2-methylbenzoate

Tolvaptan Impurity 66
CAS:1580889-29-7
Formula: C27H27ClN2O3
462.97
RM-T151266
N-(4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-3,4-dimethylbenzamide

Tolvaptan Impurity 67
Formula: C14H12ClNO4S
325.76
RM-T151267
5-chloro-2-((4-methylphenyl)sulfonamido)benzoic acid

Tolvaptan Impurity 68
Formula: C14H18ClNO4
299.75
RM-T151268
methyl 5-chloro-2-((4-ethoxy-4-oxobutyl)amino)benzoate

Tolvaptan Impurity 69
CAS:1316312-24-9
Formula: C10H10ClN
179.65
RM-T151269
7-Chloro-2,3-dihydro-1H-benzo[b]azepine

TOLVAPTAN IMPURITY 7
CAS:1580889-33-3
Formula: C25H23ClN2O3
434.91
RM-T151207
N-(4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)benzamide

Tolvaptan Impurity 70
Formula: C52H49Cl2N4O8P
959.86
RM-T151270
bis(7-chloro-1-(2-methyl-4-(2-methylbenzamido)benzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl) hydrogen phosphate

Tolvaptan Impurity 71
Formula: C26H27N2O6P
494.48
RM-T151271
1-(2-methyl-4-(2-methylbenzamido)benzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl dihydrogen phosphate

Tolvaptan Impurity 72
CAS:1401998-56-8
Formula: C18H19NO3
297.35
RM-T151272
ethyl 2-methyl-4-(2-methylbenzamido)benzoate

Tolvaptan Impurity 73
CAS:108166-22-9
Formula: C15H13NO3
255.27
RM-T151273
4-(2-methylbenzamido)benzoic acid

Tolvaptan Impurity 74
CAS:1305606-71-6
Formula: C15H13NO3
255.27
RM-T151274
4-benzamido-2-methylbenzoic acid

Tolvaptan Impurity 75
CAS:1306528-12-0
Formula: C16H15NO3
269.3
RM-T151275
2-methyl-4-(4-methylbenzamido)benzoic acid

Tolvaptan Impurity 76
CAS:1030654-92-2
Formula: C16H15NO3
269.3
RM-T151276
2-methyl-3-(2-methylbenzamido)benzoic acid

Tolvaptan Impurity 77
CAS:137977-65-2
Formula: C26H24N2O3
412.49
RM-T151277
2-methyl-N-(3-methyl-4-(5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)benzamide

Tolvaptan Impurity 78
CAS:137977-35-6
Formula: C25H21ClN2O3
432.9
RM-T151278
N-(4-(7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-2-methylbenzamide

Tolvaptan Impurity 79
Formula: C26H23ClN2O3
446.93
RM-T151279
N-(3-(7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-2-methylphenyl)-2-methylbenzamide

TOLVAPTAN IMPURITY 8
CAS:1580889-25-3
Formula: C26H25ClN2O3
448.94
RM-T151208
N-(4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-4-methylbenzamide

Tolvaptan Impurity 80
Formula: C28H29ClN2O4
493
RM-T151280
N-(4-(7-chloro-5,5-dimethoxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

Tolvaptan Impurity 81
CAS:2468638-31-3
Formula: C27H25ClN2O3
460.96
RM-T151281
N-(4-(7-chloro-5-methoxy-2,3-dihydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

Tolvaptan Impurity 82
Formula: C26H24Cl2N2O2
467.39
RM-T151282
N-(4-(5,7-dichloro-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

Tolvaptan Impurity 83
Formula: C32H39ClN3O2 Cl
533.13 35.45
RM-T151283
7-chloro-N,N,N-triethyl-1-(2-methyl-4-(2-methylbenzamido)benzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-aminium chloride

Tolvaptan Impurity 84
Formula: C25H24ClN2O6P
514.9
RM-T151284
7-chloro-1-(4-(2-methylbenzamido)benzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl dihydrogen phosphate

Tolvaptan Impurity 85
Formula: C25H24ClN2O6P
514.9
RM-T151285
1-(4-benzamido-2-methylbenzoyl)-7-chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl dihydrogen phosphate

Tolvaptan Impurity 86
Formula: C26H26ClN2O6P
528.93
RM-T151286
7-chloro-1-(2-methyl-4-(4-methylbenzamido)benzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl dihydrogen phosphate

Tolvaptan Impurity 87
Formula: C26H26ClN2O6P
528.93
RM-T151287
7-chloro-1-(2-methyl-4-(3-methylbenzamido)benzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl dihydrogen phosphate

Tolvaptan Impurity 88
Formula: C26H26ClN2O6P
528.93
RM-T151288
7-chloro-1-(2-methyl-3-(2-methylbenzamido)benzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl dihydrogen phosphate

Tolvaptan Impurity 89
CAS:3951-89-1
Formula: C10H10BrNO
240.1
RM-T151289
7-bromo-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one

TOLVAPTAN IMPURITY 9
CAS:137973-76-3
Formula: C26H23ClN2O3
446.93
RM-T151209
N-(4-(7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

Tolvaptan Impurity 90
Formula: C34H31ClN2O4
567.08
RM-T151290
N-(4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methyl-N-(2-methylbenzoyl)benzamide

Tolvaptan Impurity 91
CAS:5468-96-2
Formula: C9H8Cl2O2
219.06
RM-T151291
2,4-dichlorobenzyl acetate

Tolvaptan Impurity 92
Formula: C25H21ClN2O2
416.91
RM-T151292
N-(4-(7-chloro-2,3-dihydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-2-methylbenzamide

Tolvaptan Impurity 93
Formula: C26H27ClN3O6P
543.94
RM-T151293
1-(4-(4-amino-2-methylbenzamido)-2-methylbenzoyl)-7-chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl dihydrogen phosphate

Tolvaptan Impurity 94
Formula: C34H33ClN3O7P
662.08
RM-T151294
7-chloro-1-(2-methyl-4-(2-methyl-4-(2-methylbenzamido)benzamido)benzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl dihydrogen phosphate

Tolvaptan Impurity 95
CAS:942619-88-7
Formula: C27H28ClN2O6P
542.95
RM-T151295
7-chloro-1-(2-methyl-4-(2-methylbenzamido)benzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl methyl hydrogen phosphate

Tolvaptan Impurity 96
CAS:1114219-87-2
Formula: C28H30ClN2O6P
556.98
RM-T151296
7-chloro-1-(2-methyl-4-(2-methylbenzamido)benzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl dimethyl phosphate

Tolvaptan Impurity 97
Formula: C29H32ClN2O7P
587.01
RM-T151297
7-chloro-1-(2-methyl-4-(2-methylbenzamido)benzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl (2-hydroxyethyl) methyl phosphate

Tolvaptan Impurity 98
CAS:2458812-63-8
Formula: C24H22N2O4
402.45
RM-T151298
2-methyl-4-(2-methyl-4-(2-methylbenzamido)benzamido)benzoic acid

Tolvaptan Nitroso Impurity 109
Formula: C10H9ClN2O2
224.64
RM-T152309
7-chloro-1-nitroso-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one

TONALIDE
CAS:21145-77-7
Formula: C18H26O
258.41
RG-A262543
1-(3,5,5,6,8,8-hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethan-1-one

TOPIRAMATE
CAS:97240-79-4
Formula: C12H21NO8S
339.36
RM-T150100
((3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)methyl sulfamate

TOPIRAMATE D12
CAS:1279037-95-4
Formula: C12H9D12NO8S
351.43
RM-T150124
((3aS,5aR,8aR,8bS)-2,2,7,7-tetrakis(methyl-d3)tetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)methyl sulfamate

TOPIRAMATE EP IMPURITY A
CAS:20880-92-6
Formula: C12H20O6
260.28
RM-T150105
((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)methanol

TOPIRAMATE EP IMPURITY B
CAS:876403-98-4
Formula: C17H30N2O9S
438.49
RM-T150106
((3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)methyl diethylcarbamoylsulfamate

Topiramate EP Impurity C
CAS:106881-41-8
Formula: C9H17NO8S
299.29
RM-T150107
((3aS,6R,7R,7aS)-6,7-dihydroxy-2,2-dimethyltetrahydro-3aH-[1,3]dioxolo[4,5-b]pyran-3a-yl)methyl sulfamate

TOPIRAMATE EP IMPURITY D
CAS:950603-46-0
Formula: C25H39NO15S
625.64
RM-T150108
((3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)methyl (((3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)methoxy)carbonylsulfamate