Quality Control Solutions Ltd (Page 44) @ ChemBuyersGuide.com, Inc.

NEOMYCIN B TRISULFATE
CAS:4146-30-9
Formula: C23H46N6O13 3H2SO4
614.64 294.22
RM-N150302
Actilin; Actiline; Antibiotic 10676; Antibiotique EF 185; (2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-(((2R,3S,4R,5S)-5-(((1R,2R,3S,5R,6S)-3,5-diamino-2-(((2R,3R,4R,5S,6R)-3-amino-6-(aminomethyl)-4,5-dihydroxytetrahydro-2H-pyran-2-yl)oxy)-6-

Neomycin C;Framycetin sulfate EP Impurity C;Neomycin sulfate EP Impurity C
CAS:66-86-4
Formula: C23H46N6O13
614.64
RM-F180103
(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-(((2R,3S,4R,5S)-5-(((1R,2R,3S,5R,6S)-3,5-diamino-2-(((2R,3R,4R,5S,6R)-3-amino-6-(aminomethyl)-4,5-dihydroxytetrahydro-2H-pyran-2-yl)oxy)-6-hydroxycyclohexyl)oxy)-4-hydroxy-2-(hydroxymethyl)tetrahyd

NEOMYCIN SULPHATE
CAS:1405-10-3
Formula: C23H46N6O13 H2SO4
614.64 98.08
RM-N150300
(2S,3S,4R,5R)-5-amino-2-(aminomethyl)-6-(((2R,3S,4R,5S)-5-(((1R,2R,3S,5R,6S)-3,5-diamino-2-(((2R,3R,4R,5S,6R)-3-amino-6-(aminomethyl)-4,5-dihydroxytetrahydro-2H-pyran-2-yl)oxy)-6-hydroxycyclohexyl)oxy)-4-hydroxy-2-(hydroxymethyl)tetrahydrof

Neomycin Sulphate Impurity 4
Formula: C8H16N2O4
204.23
RM-N150304
2-(((1r,2R,3S,5R,6S)-3,5-diamino-2,6-dihydroxycyclohexyl)oxy)acetaldehyde

NEOPENTYL 4-METHYLBENZENESULFONATE
CAS:2346-07-8
Formula: C12H18O3S
242.33
RG-E140729
neopentyl 4-methylbenzenesulfonate

NEOPENTYL PIVALATE
CAS:5340-26-1
Formula: C10H20O2
172.27
RG-E141092
neopentyl pivalate

NEOPHYTADIENE
CAS:504-96-1
Formula: C20H38
278.52
RG-A262386
7,11,15-trimethyl-3-methylenehexadec-1-ene

NEOSTIGMINE BROMIDE
CAS:114-80-7
Formula: C12H19BrN2O2
303.2
RM-N051500
3-((dimethylcarbamoyl)oxy)-N,N,N-trimethylbenzenaminium bromide

Neostigmine Bromide EP Impurity A Iodide
Formula: C9H14NO*I
152.22*126.91
RM-N051501
3-hydroxy-N,N,N-trimethylbenzenaminium iodide

Neostigmine Bromide EP Impurity B; Edrophonium Chloride EP Impurity A
CAS:99-07-0
Formula: C8H11NO
137.18
RM-N051502
3-(dimethylamino)phenol

Neostigmine Bromide EP Impurity C
CAS:16088-19-0
Formula: C11H16N2O2
208.26
RM-N051503
3-(Dimethylamino)phenyl dimethylcarbamate

Neostigmine Bromide Impurity 10
Formula: C23H33N4O4 CH3O4S
429.54 111.09
RM-N051510
3-((dimethylcarbamoyl)oxy)-4-(((3-((dimethylcarbamoyl)oxy)phenyl)(methyl)amino)methyl)-N,N,N-trimethylbenzenaminium methyl sulfate

Neostigmine Bromide Impurity 11
Formula: C25H38N4O4 2CH3O4S
680.79 222.18
RM-N051511
5-((dimethylcarbamoyl)oxy)-2-(2-((dimethylcarbamoyl)oxy)-4-(trimethylammonio)benzyl)-N,N,N-trimethylbenzenaminium methyl sulfate

NEOSTIGMINE BROMIDE IMPURITY 13
CAS:14703-69-6
Formula: C7H9NO
123.15
RM-N051513
3-(Methylamino)phenol

Neostigmine Bromide Impurity 14
CAS:14318-66-2
Formula: C8H11NO
137.18
RM-N051514
3-methoxy-N-methylaniline

Neostigmine Bromide Impurity 15
Formula: C16H20N2O2
272.34
RM-N051515
3,3'-peroxybis(N,N-dimethylaniline)

Neostigmine Bromide Impurity 16
CAS:76418-45-6
Formula: C10H14N2O2
194.23
RM-N051516
3-(methylamino)phenyl dimethylcarbamate

Neostigmine Bromide Impurity 17
Formula: C13H19N3O3
265.31
RM-N051517
3-(1,3,3-trimethylureido)phenyl dimethylcarbamate

Neostigmine Bromide Impurity 18
Formula: C11H16N2O2
208.26
RM-N051518
1-(3-methoxyphenyl)-1,3,3-trimethylurea

NEOSTIGMINE BROMIDE IMPURITY 4
CAS:19962-04-0
Formula: C9H12N2O2
180.2
RM-N051504
3-Aminophenyl dimethylcarbamate

Neostigmine Bromide Impurity 5
Formula: C13H20N2O2
236.31
RM-N051505
3-(isopropyl(methyl)amino)phenyl dimethylcarbamate

Neostigmine Bromide Impurity 6
Formula: C15H24N2O2
264.36
RM-N051506
3-(diisopropylamino)phenyl dimethylcarbamate

NEOSTIGMINE BROMIDE IMPURITY 7
CAS:3743-22-4
Formula: C8H11NO
137.18
RM-N051507
2-(dimethylamino)phenol

NEOSTIGMINE BROMIDE IMPURITY 8
CAS:619-60-3
Formula: C8H11NO
137.18
RM-N051508
4-(dimethylamino)phenol

Neostigmine Bromide Impurity 9
CAS:611-24-5
Formula: C7H9NO
123.15
RM-N051509
2-(METHYLAMINO)PHENOL

NEOSTIGMINE IMPURITY 1
CAS:39218-17-2
Formula: C10H16NO*CH3O4S
166.24*111.09
RG-A261502
3-methoxy-N,N,N-trimethylbenzenaminium methyl sulfate

Neostigmine Impurity 19
CAS:10603-61-9
Formula: C6H7NO2
125.13
RM-N051519
3-(hydroxyamino)phenol

Neostigmine Impurity 20
CAS:20031-38-3
Formula: C6H5NO2
123.11
RM-N051520
3-nitrosophenol

Neostigmine Impurity 21
CAS:64050-77-7
Formula: C11H17N2O2*CH3O4S
209.27*111.09
RM-N051521
N,N,N-trimethyl-3-((methylcarbamoyl)oxy)benzenaminium methyl sulfate

Neostigmine Impurity 22
CAS:64051-18-9
Formula: C10H15N2O2 CH3O4S
195.24 111.09
RM-N051522
3-(carbamoyloxy)-N,N,N-trimethylbenzenaminium methyl sulfate

Neostigmine Impurity 23
CAS:4939-59-7
Formula: C12H17N3O3
251.29
RM-N051523
3-(3,3-dimethylureido)phenyl dimethylcarbamate

Neostigmine Impurity 24
CAS:4849-46-1
Formula: C9H12N2O2
180.21
RM-N051524
3-(3-hydroxyphenyl)-1,1-dimethylurea

Neostigmine Impurity 25
CAS:63468-95-1
Formula: C17H22N2O2
286.38
RM-N051525
6,6'-methylenebis(3-(dimethylamino)phenol)

Neostigmine Impurity 26
Formula: C26H33N3O3
435.57
RM-N051526
6,6'-((4-(dimethylamino)-6-hydroxy-1,3-phenylene)bis(methylene))bis(3-(dimethylamino)phenol)

Neostigmine Impurity 27
CAS:20734-67-2
Formula: C6H7NO2
125.13
RM-N051527
5-aminobenzene-1,3-diol

Neostigmine Impurity 28
CAS:56140-38-6
Formula: C9H13NO
151.21
RM-N051528
5-(dimethylamino)-2-methylphenol

Neostigmine Impurity 29
Formula: C17H22N2O2
286.38
RM-N051529
5-(dimethylamino)-2-(2-(dimethylamino)-4-hydroxybenzyl)phenol

Neostigmine Impurity 30
Formula: C17H22N2O2
286.38
RM-N051530
4,4'-methylenebis(3-(dimethylamino)phenol)

Neostigmine Impurity 31
CAS:2631-39-2
Formula: C10H14N2O2
194.23
RM-N051531
3-(dimethylamino)phenyl methylcarbamate

Neostigmine Impurity 32
CAS:855839-29-1
Formula: C9H12N2O2
180.21
RM-N051532
3-(dimethylamino)phenyl carbamate

Neostigmine Impurity 33
Formula: C9H10N2O3
194.19
RM-N051533
3-nitrosophenyl dimethylcarbamate

Neostigmine Impurity 34
Formula: C23H32N4O4
428.53
RM-N051534
methylenebis(5-(dimethylamino)-2,1-phenylene) bis(dimethylcarbamate)

Neostigmine Impurity 35
Formula: C8H17N3O3
203.24
RM-N051535
2-(3,3-dimethylureido)ethyl dimethylcarbamate

Neostigmine Impurity 36
Formula: C24H35N4O4 Br
443.57 79.90
RM-N051536
4-(4-(dimethylamino)-2-((dimethylcarbamoyl)oxy)benzyl)-3-((dimethylcarbamoyl)oxy)-N,N,N-trimethylbenzenaminium bromide

Neostigmine Impurity 37
Formula: C10H14N2O2
194.23
RM-N051537
1-(3-hydroxyphenyl)-1,3,3-trimethylurea

NEOSTIGMINE METILSULFATE
CAS:51-60-5
Formula: C12H19N2O2 CH3O4S
223.30 111.09
RM-N051512
3-((dimethylcarbamoyl)oxy)-N,N,N-trimethylbenzenaminium methyl sulfate

Neostigmine Nitroso Impurity 38
Formula: C10H13N3O3
223.23
RM-N051538
3-(methyl(nitroso)amino)phenyl dimethylcarbamate

NEOTAME
CAS:165450-17-9
Formula: C20H30N2O5
378.46
RM-N050100
(S)-3-((3,3-dimethylbutyl)amino)-4-(((S)-1-methoxy-1-oxo-3-phenylpropan-2-yl)amino)-4-oxobutanoic acid

NEOTAME RELATED COMPOUND A
CAS:190910-14-6
Formula: C19H28N2O5
364.44
RM-N050101
(S)-4-(((S)-1-Carboxy-2-phenylethyl)amino)-3-((3,3-dimethylbutyl)amino)-4-oxobutanoic acid

NEPAFENAC D5
CAS:1246814-53-8
Formula: C15H9D5N2O2
259.32
RM-N311004
2-(2-amino-3-(benzoyl-d5)phenyl)acetamide

NEPAFENAC IMPURITY 2
CAS:98790-48-8
Formula: C14H11NO3
241.25
RM-N311002
2-amino-3-benzoylbenzoic acid

NEPAFENAC IMPURITY 3
CAS:1881270-49-0
Formula: C15H12N2O2
252.27
RM-N311003
8-benzoyl-1,4-dihydrocinnolin-3(2H)-one

NEPETALACTONE
CAS:490-10-8
Formula: C10H14O2
166.22
RG-E140388
4,7-dimethyl-5,6,7,7a-tetrahydrocyclopenta[c]pyran-1(4aH)-one

NEPETALACTONE CIS-TRANS-FORM
CAS:21651-62-7
Formula: C10H14O2
166.22
RM-N052701
(4aS,7S,7aR)-4,7-dimethyl-5,6,7,7a-tetrahydrocyclopenta[c]pyran-1(4aH)-one

NERATINIB
CAS:698387-09-6
Formula: C30H29ClN6O3
557.04
RM-N051800
(E)-N-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide

NERATINIB IMPURITY 10
CAS:1144516-17-5
Formula: C31H27ClN6O5
599.04
RM-N051810
N-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-1-methyl-2,3-dioxopiperidine-4-carboxamide

NERATINIB IMPURITY 11
CAS:1144516-18-6n+êfree basen+ë
Formula: C31H32ClN6O3*Cl
572.09*35.45
RM-N051811
(E)-4-((4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)amino)-N,N,N-trimethyl-4-oxobut-2-en-1-aminium chloride

NERATINIB IMPURITY 12
Formula: C29H27ClN6O2
527.02
RM-N051812
(E)-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxy-6-((1-methylpyrrolidin-2-ylidene)amino)quinoline-3-carbonitrile

NERATINIB IMPURITY 13
CAS:1144516-19-7
Formula: C28H25ClN6O4
544.99
RM-N051813
N1-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-N2,N2-dimethyloxalamide

NERATINIB IMPURITY 14
CAS:1144516-14-2
Formula: C26H21ClN6O4
516.94
RM-N051814
N1-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)oxalamide

NERATINIB IMPURITY 17
Formula: C30H29ClN6O3
557.04
RM-N051817
(Z)-N-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide

NERATINIB IMPURITY 18
CAS:848133-75-5
Formula: C14H13N3O3
271.27
RM-N051818
N-(3-Cyano-7-ethoxy-4-hydroxyquinolin-6-yl)acetamide

NERATINIB IMPURITY 19
CAS:20629-35-0
Formula: C4H5BrO2
164.99
RM-N051819
4-bromobut-2-enoic acid

NERATINIB IMPURITY 2
CAS:1144516-15-3
Formula: C28H24ClN5O4
529.97
RM-N051802
4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxy-6-(2-hydroxy-5-oxopyrrolidin-1-yl)quinoline-3-carbonitrile

NERATINIB IMPURITY 20
Formula: C9H17NO2
171.24
RM-N051820
isopropyl (E)-4-(dimethylamino)but-2-enoate

NERATINIB IMPURITY 21
Formula: C6H10BrNO
192.06
RM-N051821
(E)-4-bromo-N,N-dimethylbut-2-enamide

NERATINIB IMPURITY 22
CAS:77825-56-0
Formula: C6H10O2
114.14
RM-N051822
ethyl (E)-but-2-enoate

Neratinib Impurity 23
CAS:6284-46-4
Formula: C7H12O2
128.17
RM-N051823
isopropyl (E)-but-2-enoate

Neratinib Impurity 24
Formula: C6H11NO
113.16
RM-N051824
(E)-N,N-dimethylbut-2-enamide

Neratinib Impurity 25
CAS:13991-36-1
Formula: C4H5BrO2
164.99
RM-N051825
(E)-4-bromobut-2-enoic acid

Neratinib Impurity 26
CAS:37746-78-4
Formula: C6H9BrO2
193.04
RM-N051826
ethyl (E)-4-bromobut-2-enoate

Neratinib Impurity 27
CAS:127322-74-1
Formula: C7H11BrO2
207.07
RM-N051827
isopropyl (E)-4-bromobut-2-enoate

Neratinib Impurity 28
Formula: C8H16N2O
156.23
RM-N051828
(E)-4-(dimethylamino)-N,N-dimethylbut-2-enamide

Neratinib Impurity 29
Formula: C16H19N3O4
317.35
RM-N051829
ethyl (E)-3-((4-acetamido-3-ethoxyphenyl)amino)-2-cyanoacrylate

NERATINIB IMPURITY 3
Formula: C50H38Cl2N10O6
945.81
RM-N051803
N1,N2-bis(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)oxalamide

Neratinib Impurity 30
CAS:1376615-55-2
Formula: C30H29ClN6O4
573.05
RM-N051830
(E)-4-((4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)amino)-N,N-dimethyl-4-oxobut-2-en-1-amine oxide

Neratinib Impurity 31
CAS:927802-54-8
Formula: C10H13NO3
195.22
RM-N051831
Methyl 3-amino-4-ethoxybenzoate

Neratinib Impurity 32
CAS:1201080-20-7
Formula: C12H15NO4
237.26
RM-N051832
Methyl 3-acetamido-4-ethoxybenzoate

Neratinib Impurity 33
CAS:1222172-49-7
Formula: C12H16N2O4
252.27
RM-N051833
methyl 5-acetamido-2-amino-4-ethoxybenzoate

Neratinib Impurity 34
CAS:4377-33-7
Formula: C6H6ClN
127.57
RM-N051834
2-(Chloromethyl)pyridine

Neratinib Impurity 35
CAS:179687-79-7
Formula: C12H9ClN2O3
264.67
RM-N051835
2-((2-Chloro-4-nitrophenoxy)methyl)pyridine

Neratinib Impurity 36
CAS:102137-46-2
Formula: C12H12N2O
200.24
RM-N051836
4-(pyridin-2-ylmethoxy)aniline

Neratinib Impurity 37
CAS:6000-00-6
Formula: C5H7BrO2
179.01
RM-N051837
methyl (E)-4-bromobut-2-enoate

Neratinib Impurity 38
CAS:212776-19-7
Formula: C7H13NO2
143.19
RM-N051838
methyl (E)-4-(dimethylamino)but-2-enoate

Neratinib Impurity 39
Formula: C8H15NO2
157.21
RM-N051839
ethyl (E)-4-(dimethylamino)but-2-enoate

NERATINIB IMPURITY 4
CAS:1144516-20-0
Formula: C25H20ClN5O3
473.91
RM-N051804
N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide

Neratinib Impurity 40
CAS:848133-76-6
Formula: C14H12ClN3O2
289.72
RM-N051840
N-(4-chloro-3-cyano-7-ethoxyquinolin-6-yl)acetamide

Neratinib Impurity 41
CAS:524955-09-7
Formula: C12H11ClN2O
234.68
RM-N051841
3-chloro-4-(pyridin-2-ylmethoxy)aniline

Neratinib Impurity 42
Formula: C12H11N3O2
229.24
RM-N051842
6-amino-7-ethoxy-4-hydroxyquinoline-3-carbonitrile

Neratinib Impurity 43
CAS:848133-87-9
Formula: C12H10ClN3O
247.68
RM-N051843
6-AMINO-4-CHLORO-7-ETHOXYQUINOLINE-3-CARBONITRILE

Neratinib Impurity 44
Formula: C24H21N5O2
411.47
RM-N051844
6-amino-7-ethoxy-4-((4-(pyridin-2-ylmethoxy)phenyl)amino)quinoline-3-carbonitrile

Neratinib Impurity 45
CAS:915941-95-6
Formula: C26H22ClN5O3
487.94
RM-N051845
N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)acetamide

Neratinib Impurity 46
Formula: C26H24ClN5O2
473.96
RM-N051846
4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxy-6-(ethylamino)quinoline-3-carbonitrile

Neratinib Impurity 47
CAS:848139-78-6
Formula: C24H20ClN5O2
445.91
RM-N051847
6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile

Neratinib Impurity 48
Formula: C30H31ClN6O3
559.07
RM-N051848
N-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)butanamide

Neratinib Impurity 49
Formula: C28H27ClN6O2
515.01
RM-N051849
(E)-N'-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-N,N-dimethylacetimidamide

NERATINIB IMPURITY 5
Formula: C30H29ClN6O4
573.04
RM-N051805
(E)-N-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)(hydroxy)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide

Neratinib Impurity 50
CAS:1201080-23-0
Formula: C12H14N2O6
282.25
RM-N051850
methyl 5-acetamido-4-ethoxy-2-nitrobenzoate

Neratinib Impurity 51
CAS:69954-66-1
Formula: C6H13NO2
131.18
RM-N051851
4-(dimethylamino)butanoic acid

Neratinib Impurity 52
CAS:94-05-3
Formula: C8H11NO3
169.18
RM-N051852
Ethyl 2-cyano-3-ethoxyacrylate

Neratinib Impurity 53
Formula: C12H14N2O6
282.25
RM-N051853
ethyl 2-((ethoxycarbonyl)amino)-3-nitrobenzoate

Neratinib Impurity 54
Formula: C9H10N2O4
210.19
RM-N051854
ethyl 2-amino-3-nitrobenzoate

Neratinib Impurity 55
Formula: C29H26ClN5O2
512.01
RM-N051855
4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-6-(cyclopentylideneamino)-7-ethoxyquinoline-3-carbonitrile

Neratinib Impurity 56
CAS:1144516-21-1
Formula: C29H27ClN6O2
527.03
RM-N051856
4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxy-6-((1-methylpyrrolidin-2-ylidene)amino)quinoline-3-carbonitrile

Neratinib Impurity 57
CAS:1376619-98-5
Formula: C30H31ClN6O4
575.07
RM-N051857
(E)-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-6-(4-(dimethylamino)but-2-enamido)-7-ethoxyquinoline-3-carboxamide

Neratinib Impurity 58
Formula: C24H22ClN5O3
463.92
RM-N051858
6-amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carboxamide

Neratinib Impurity 59
Formula: C30H30ClN6O4
574.06
RM-N051859
(E)-N-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(hydroxydimethyl-l4-azanyl)but-2-enamide

NERATINIB IMPURITY 6
Formula: C30H29ClN6O4
573.04
RM-N051806
(E)-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-6-(4-(dimethylamino)but-2-enamido)-7-ethoxyquinoline 1-oxide

Neratinib Impurity 60
CAS:871895-08-8
Formula: C10H12N2O4
224.22
RM-N051860
N-(3-ethoxy-4-nitrophenyl)acetamide

Neratinib Impurity 61
CAS:214476-09-2
Formula: C12H8ClN3O3
277.66
RM-N051861
4-chloro-7-ethoxy-6-nitroquinoline-3-carbonitrile

Neratinib Impurity 64
Formula: C54H49Cl2N11O5
1002.96
RM-N051864
N-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-3-((4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)amino)-4-(dimethylamino)butanamide

Neratinib Impurity 65
Formula: C30H31ClN6O4
575.07
RM-N051865
3-((4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)amino)-4-(dimethylamino)butanoic acid

Neratinib Impurity 66
Formula: C12H8ClN3O2
261.67
RM-N051866
N-(4-chloro-3-cyano-7-hydroxyquinolin-6-yl)acetamide

Neratinib Impurity 67
Formula: C25H22ClN5O2
459.93
RM-N051867
4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxy-6-(methylamino)quinoline-3-carbonitrile

Neratinib Impurity 68
Formula: C28H25ClN6O3
529
RM-N051868
(E)-N-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-hydroxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide

Neratinib Impurity 69
Formula: C30H29ClN6O4
573.05
RM-N051869
4-((4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)amino)-N,N-dimethyl-4-oxobut-2-en-1-amine oxide

NERATINIB IMPURITY 7
CAS:1144516-13-1
Formula: C26H20ClN5O5
517.92
RM-N051807
2-((4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)amino)-2-oxoacetic acid

Neratinib Impurity 70
CAS:1222172-50-0
Formula: C15H17N3O4
303.32
RM-N051870
methyl 5-acetamido-2-((2-cyanovinyl)amino)-4-ethoxybenzoate

Neratinib Impurity 71
Formula: C15H17N3O4
303.32
RM-N051871
methyl (E)-5-acetamido-2-((2-cyanovinyl)amino)-4-ethoxybenzoate

Neratinib Impurity 72
Formula: C26H24ClN5O2
473.96
RM-N051872
6-amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)(ethyl)amino)-7-ethoxyquinoline-3-carbonitrile

Neratinib Impurity 73
Formula: C28H28ClN5O2
502.02
RM-N051873
4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-6-(diethylamino)-7-ethoxyquinoline-3-carbonitrile

Neratinib Impurity 74
Formula: C12H14N2O6
282.25
RM-N051874
methyl 3-acetamido-4-ethoxy-2-nitrobenzoate

Neratinib Impurity 75
Formula: C12H13N3O8
327.25
RM-N051875
methyl 3-acetamido-4-ethoxy-2,6-dinitrobenzoate

Neratinib Impurity 76
Formula: C12H16N2O4
252.27
RM-N051876
methyl 3-acetamido-2-amino-4-ethoxybenzoate

Neratinib Impurity 77
Formula: C12H17N3O4
267.29
RM-N051877
methyl 3-acetamido-2,6-diamino-4-ethoxybenzoate

NERATINIB IMPURITY 8
Formula: C30H29ClN6O4
573.04
RM-N051808
N-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-3-((dimethylamino)methyl)oxirane-2-carboxamide

Neratinib Impurity 82
CAS:1469746-91-5
Formula: C30H30N6O3
522.61
RM-N051882
(E)-N-(3-cyano-7-ethoxy-4-((4-(pyridin-2-ylmethoxy)phenyl)amino)quinolin-6-yl)-4-(dimethylamino)but-2-enamide

Neratinib Impurity 83
Formula: C12H9ClN2O2
248.67
RM-N051883
2-((2-chloro-4-nitrosophenoxy)methyl)pyridine

Neratinib Impurity 84
Formula: C12H11ClN2O2
250.68
RM-N051884
N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)hydroxylamine

Neratinib Impurity 85
CAS:848134-24-7
Formula: C12H11ClN2O
234.68
RM-N051885
3-chloro-4-(pyridin-3-ylmethoxy)aniline

Neratinib Impurity 86
CAS:105326-69-0
Formula: C12H11ClN2O
234.68
RM-N051886
3-chloro-4-(pyridin-4-ylmethoxy)aniline

Neratinib Impurity 87
CAS:937605-75-9
Formula: C12H11ClN2O
234.68
RM-N051887
3-chloro-2-(pyridin-2-ylmethoxy)aniline

NERATINIB IMPURITY 9
CAS:1144516-16-4
Formula: C32H36ClN7O3
602.13
RM-N051809
N-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-3,4-bis(dimethylamino)butanamide

NERATINIB MALEATE
CAS:915942-22-2
Formula: C30H29ClN6O3 C4H4O4
557.04 116.07
RM-N051880
(E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide Maleate

Neratinib Maleate Impurity 1
Formula: C30H30Cl2N6O3
593.51
RM-N051881
3-chloro-N-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)butanamide

Neratinib Pyridine N-Oxide
Formula: C30H29ClN6O4
573.04
RM-N051816
(E)-2-((2-chloro-4-((3-cyano-6-(4-(dimethylamino)but-2-enamido)-7-ethoxyquinolin-4-yl)amino)phenoxy)methyl)pyridine 1-oxide

NERIDRONIC ACID
CAS:79778-41-9
Formula: C6H17NO7P2
277.15
RM-N051400
(6-amino-1-hydroxyhexane-1,1-diyl)diphosphonic acid

Nerolidol Impurity 4
Formula: C15H26O2
238.37
RM-N332104
(R)-6-methyl-2-((2R,5S)-5-methyl-5-vinyltetrahydrofuran-2-yl)hept-5-en-2-ol

Nerolidol Impurity 5
Formula: C15H26O2
238.37
RM-N332105
(R)-6-methyl-2-((2S,5S)-5-methyl-5-vinyltetrahydrofuran-2-yl)hept-5-en-2-ol

NERVONIC ACID
CAS:506-37-6
Formula: C24H46O2
366.63
RG-A263531
(Z)-tetracos-15-enoic acid

NERYL ACETATE
CAS:141-12-8
Formula: C12H20O2
196.29
RG-A261833
(Z)-3,7-Dimethylocta-2,6-dien-1-yl acetate

NETARSUDIL
CAS:1254032-66-0
Formula: C28H27N3O3
453.53
RM-N052800
(S)-4-(3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate

NETARSUDIL IMPURITY 1
CAS:1253955-20-2
Formula: C33H35N3O5
553.65
RM-N052801
(R)-4-(3-((tert-butoxycarbonyl)amino)-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate

NETARSUDIL IMPURITY 2
CAS:1254032-67-1
Formula: C28H27N3O3
453.53
RM-N052802
(R)-4-(3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate

NETARSUDIL IMPURITY 3
CAS:2098444-97-2
Formula: C24H29NO6
427.49
RM-N052803
(R)-3-((tert-butoxycarbonyl)amino)-2-(4-(((2,4-dimethylbenzoyl)oxy)methyl)phenyl)propanoic acid

NETARSUDIL IMPURITY 4
CAS:2097334-21-7
Formula: C28H27NO5
457.52
RM-N052804
(S)-4-(2-(4-benzyl-2-oxooxazolidin-3-yl)-2-oxoethyl)benzyl 2,4-dimethylbenzoate

NETARSUDIL IMPURITY 5
CAS:2250308-75-7
Formula: C34H38N2O7
586.67
RM-N052805
4-((R)-1-((R)-4-benzyl-2-oxooxazolidin-3-yl)-3-((tert-butoxycarbonyl)amino)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate

NETICONAZOLE
CAS:130726-68-0
Formula: C17H22N2OS
302.43
RM-N200300
(E)-1-(2-(methylthio)-1-(2-(pentyloxy)phenyl)vinyl)-1H-imidazole

Neticonazole Impurity 1
CAS:138206-50-5
Formula: C12H12N2OS
232.3
RM-N200327
(Z)-2-(1-(1H-imidazol-1-yl)-2-(methylthio)vinyl)phenol

Neticonazole Impurity 10
Formula: C17H22N2O2S
318.44
RM-N200336
(E)-1-(2-(methylthio)-1-(2-(pentyloxy)phenyl)vinyl)-1H-imidazole 3-oxide

Neticonazole Impurity 11
CAS:56986-82-4
Formula: C9H10O2S
182.24
RM-N200337
1-(2-hydroxyphenyl)-2-(methylthio)ethan-1-one

Neticonazole Impurity 2
CAS:138206-84-5
Formula: C17H22N2OS
302.43
RM-N200328
(Z)-1-(2-(methylthio)-1-(2-(pentyloxy)phenyl)vinyl)-1H-imidazole

Neticonazole Impurity 3
CAS:624-92-0
Formula: C2H6S2
94.2
RM-N200329
1,2-dimethyldisulfane

NETICONAZOLE IMPURITY 4
CAS:98984-65-7
Formula: C2H6O2S2
126.2
RM-N200330
Neticonazole Impurity 4

NETICONAZOLE IMPURITY 5
CAS:14128-56-4
Formula: C2H6O3S2
142.2
RM-N200331
Neticonazole Impurity 5

NETICONAZOLE IMPURITY 6
CAS:10383-49-0
Formula: C2H6O4S2
158.2
RM-N200332
dimethyl disulfone

NETICONAZOLE IMPURITY 7
CAS:13882-12-7
Formula: C2H6OS2
110.2
RM-N200333
S-methyl methanesulfinothioate

Neticonazole Impurity 8
CAS:2949-92-0
Formula: C2H6O2S2
126.2
RM-N200334
S-Methyl methanesulfonothioate

Neticonazole Impurity 9
Formula: C12H12N2OS
232.3
RM-N200335
(E)-1-(2-(methylthio)-1-phenylvinyl)-1H-imidazole 3-oxide

Netilmicin Impurity 11
Formula: C14H28N4O4
316.4
RM-N050911
(1S,2R,3R,4S,6R)-4-amino-3-(((2S,3S)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl)oxy)-6-(ethylamino)cyclohexane-1,2-diol

Netilmicin Impurity 12
Formula: C8H18N2O3
190.24
RM-N050912
(1S,2S,3R,4S,6R)-4-amino-6-(ethylamino)cyclohexane-1,2,3-triol

NETILMICIN SULFATE
CAS:56391-57-2
Formula: C42H92N10O34S5
1441.53
RM-N050910
Bis [(2R,3R,4R,5R)-2-(((1S,2S,3R,4S,6R)-4-amino-3-(((2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl)oxy)-6-(ethylamino)-2-hydroxycyclohexyl)oxy)-5-methyl-4-(methylamino)tetrahydro-2H-pyran-3,5-diol] pentasulfate

Netilmicin Sulfate EP Impurity B
CAS:67666-41-5
Formula: C15H31N3O6
349.42
RM-N050902
(2R,3R,4R,5R)-2-(((1S,2S,3R,4S,6R)-4-amino-6-(ethylamino)-2,3-dihydroxycyclohexyl)oxy)-5-methyl-4-(methylamino)tetrahydro-2H-pyran-3,5-diol

Netilmicin Sulfate EP Impurity C
CAS:63721-52-8
Formula: C23H45N5O7
503.63
RM-N050903
4-O-[6-amino-2,3,4,6-tetradeoxy-2-(ethylamino)-+¦-Dglycero-hex-4-enopyranosyl]-2-deoxy-6-O-[3-deoxy-4- C-methyl-3-(methylamino)-+¦-L-arabinopyranosyl]-1-Nethyl-D-streptamine (2GÇ¦-N-ethylnetilmicin); (2R,3R,4R,5R)-2-(((1S,2S,3R,4S,6R)-4-amino-3

Netilmicin Sulfate EP Impurity D
CAS:63721-51-7
Formula: C23H45N5O7
503.63
RM-N050904
4-O-[2-amino-2,3,4,6-tetradeoxy-6-(ethylamino)-+¦-Dglycero-hex-4-enopyranosyl]-2-deoxy-6-O-[3-deoxy-4- C-methyl-3-(methylamino)-+¦-L-arabinopyranosyl]-1-Nethyl-D-streptamine (6GÇ¦-N-ethylnetilmicin); (2R,3R,4R,5R)-2-(((1S,2S,3R,4S,6R)-4-amino-3

Netobimin Impurity 1
Formula: C18H18N4O
306.36
RM-N052001
(E)-4-(But-1-en-1-yl)-11-cyclopropyl-5H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6(11H)-one

NETUPITANT
CAS:290297-26-6
Formula: C30H32F6N4O
578.59
RM-N202100
2-(3,5-Bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)propanamide

NETUPITANT IMPURITY 10
Formula: C17H19ClN2O
302.8
RM-N202110
N-(tert-butyl)-2-chloro-4-(o-tolyl)nicotinamide

NETUPITANT IMPURITY 11
Formula: C17H19ClN2O
302.8
RM-N202111
N-(tert-butyl)-6-chloro-4-(p-tolyl)nicotinamide

NETUPITANT IMPURITY 12
CAS:289686-73-3
Formula: C11H8F6O2
286.17
RM-N202112
2-(3,5-bis(trifluoromethyl)phenyl)propanoic acid

NETUPITANT IMPURITY 13
Formula: C13H12F6O2
314.22
RM-N202113
2-(3,5-bis(trifluoromethyl)phenyl)-2-methylbutanoic acid

NETUPITANT IMPURITY 14
Formula: C17H20N4O
296.37
RM-N202114
6-(piperazin-1-yl)-4-(o-tolyl)nicotinamide

NETUPITANT IMPURITY 15
CAS:2347562-52-9
Formula: C18H21N3O2
311.38
RM-N202115
6-(4-methylpiperazin-1-yl)-4-(o-tolyl)nicotinic acid

NETUPITANT IMPURITY 16
CAS:289686-70-0
Formula: C12H10F6O2
300.2
RM-N202116
2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropanoic acid

NETUPITANT IMPURITY 17
CAS:290297-25-5
Formula: C18H24N4
296.42
RM-N202117
N-Methyl-6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-amine

NETUPITANT IMPURITY 18
CAS:1431216-61-3
Formula: C30H32F6N4O3
610.6
RM-N202118
1-(5-(2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethylpropanamido)-4-(o-tolyl)pyridin-2-yl)-4-methylpiperazine 1,4-dioxide

NETUPITANT IMPURITY 19
Formula: C41H38F12N4O2
846.76
RM-N202119
2-(3,5-bis(trifluoromethyl)phenyl)-N-(6-(4-(2-(3,5-bis(trifluoromethyl)phenyl)-2-methylpropanoyl)piperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)-N,2-dimethylpropanamide

NETUPITANT IMPURITY 20
Formula: C30H30F6N4O2
592.59
RM-N202120
2-(3,5-bis(trifluoromethyl)phenyl)-N-(6-(4-formylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)-N,2-dimethylpropanamide

Netupitant Impurity 22
Formula: C31H34F6N4O2
608.63
RM-N202122
2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-(methoxymethyl)phenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-yl)-N,2-dimethylpropanamide

Netupitant Impurity 23
Formula: C18H22N4O2
326.4
RM-N202123
4-(5-carbamoyl-4-(o-tolyl)pyridin-2-yl)-1-methylpiperazine 1-oxide

Netupitant Impurity 24
Formula: C18H24N4
296.42
RM-N202124
(6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)methanamine

Netupitant Impurity 25
Formula: C17H22N4
282.39
RM-N202125
6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-amine

Netupitant Impurity 26
CAS:342417-01-0
Formula: C18H22N4O
310.4
RM-N202126
6-(4-methylpiperazin-1-yl)-4-(o-tolyl)nicotinamide

Netupitant Impurity 28
Formula: C30H32F6N4O3
610.6
RM-N202128
4-(5-(2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethylpropanamido)-1-oxido-4-(o-tolyl)pyridin-2-yl)-1-methylpiperazine 1-oxide

Netupitant Impurity 29
CAS:1431216-62-4
Formula: C30H32F6N4O2
594.6
RM-N202129
5-(2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethylpropanamido)-2-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridine 1-oxide

Netupitant Impurity 30
CAS:1431216-64-6
Formula: C30H32F6N4O3
610.6
RM-N202130
1-(5-(2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethylpropanamido)-1-oxido-4-(o-tolyl)pyridin-2-yl)-4-methylpiperazine 1-oxide

Netupitant Impurity 31
CAS:1431216-63-5
Formula: C30H32F6N4O2
594.6
RM-N202131
1-(5-(2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethylpropanamido)-4-(o-tolyl)pyridin-2-yl)-4-methylpiperazine 1-oxide

Netupitant Impurity 32
CAS:302912-02-3
Formula: C10H6F6O2
272.15
RM-N202132
2-(2,5-Bis(trifluoromethyl)phenyl)acetic acid

Netupitant Impurity 33
CAS:1384424-19-4
Formula: C10H6F6O2
272.15
RM-N202133
2-(3,4-bis(trifluoromethyl)phenyl)acetic acid

Netupitant Impurity 34
Formula: C18H22N4O
310.4
RM-N202134
6-(4-methylpiperazin-1-yl)-4-(m-tolyl)nicotinamide

Netupitant Impurity 35
Formula: C18H22N4O
310.4
RM-N202135
6-(4-methylpiperazin-1-yl)-4-(p-tolyl)nicotinamide

Netupitant Impurity 36
CAS:1444338-30-0
Formula: C11H6F6O4
316.16
RM-N202136
2-(3,5-bis(trifluoromethyl)phenyl)malonic acid

Netupitant Impurity 37
Formula: C12H8F6O4
330.18
RM-N202137
2-(3,5-bis(trifluoromethyl)phenyl)-2-methylmalonic acid

Netupitant Impurity 38
Formula: C13H10F6O4
344.21
RM-N202138
2-(3,5-bis(trifluoromethyl)phenyl)-3-methoxy-2-methyl-3-oxopropanoic acid

Netupitant Impurity 39
Formula: C31H34F6N4O
592.63
RM-N202139
2-(3,5-bis(trifluoromethyl)phenyl)-N-(6-(4-ethylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)-N,2-dimethylpropanamide

Netupitant Impurity 41
Formula: C14H14F6O2
328.25
RM-N202141
2-(3,5-bis(trifluoromethyl)phenyl)-2-ethylbutanoic acid

Netupitant Impurity 42
Formula: C12H10F6O2
300.2
RM-N202142
2-(2,5-bis(trifluoromethyl)phenyl)-2-methylpropanoic acid

Netupitant Impurity 43
Formula: C12H10F6O2
300.2
RM-N202143
2-(3,4-bis(trifluoromethyl)phenyl)-2-methylpropanoic acid

Netupitant Impurity 44
Formula: C12H10F6O2
300.2
RM-N202144
2-(2,3-bis(trifluoromethyl)phenyl)-2-methylpropanoic acid

Netupitant Impurity 45
Formula: C19H10F12O2
498.27
RM-N202145
2,2-bis(3,5-bis(trifluoromethyl)phenyl)propanoic acid

Netupitant Impurity 46
Formula: C13H12F6O2
314.23
RM-N202146
methyl 2-(3,5-bis(trifluoromethyl)phenyl)-2-methylpropanoate

Netupitant Impurity 47
Formula: C24H18F12O3
582.39
RM-N202147
2-(3,5-bis(trifluoromethyl)phenyl)-2-methylpropanoic anhydride

Netupitant Impurity 48
Formula: C15H14F6O4
372.26
RM-N202148
ethyl (Z)-3-(3,5-bis(trifluoromethyl)phenoxy)-3-ethoxyacrylate

Netupitant Impurity 49
Formula: C12H10F6O3
316.2
RM-N202149
2-(3,5-bis(trifluoromethyl)phenyl)-3-hydroxy-2-methylpropanoic acid

Netupitant Impurity 50
Formula: C21H28N4O4
400.48
RM-N202150
methyl (2,5-dimethoxy-6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)carbamate

Netupitant Impurity 51
Formula: C32H36F6N4O3
638.66
RM-N202151
2-(3,5-bis(trifluoromethyl)phenyl)-N-(2,5-dimethoxy-6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)-N,2-dimethylpropanamide

NETUPITANT IMPURITY A
CAS:910808-12-7
Formula: C30H32F6N4O2
594.59
RM-N202101
2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-(hydroxymethyl)phenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-yl)-N,2-dimethylpropanamide

NETUPITANT IMPURITY B
CAS:290296-72-9
Formula: C29H30F6N4O
564.57
RM-N202102
2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(6-(piperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)propanamide

Netupitant Impurity C
CAS:910808-11-6
Formula: C30H32F6N4O2
594.59
RM-N202103
4-(5-(2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethylpropanamido)-4-(o-tolyl)pyridin-2-yl)-1-methylpiperazine 1-oxide

Netupitant Impurity D
CAS:3017145-54-6
Formula: C29H30F6N4O
564.57
RM-N202104
2-(3,5-bis(trifluoromethyl)phenyl)-2-methyl-N-(6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)propanamide

Netupitant Impurity E
Formula: C28H28F6N4O
550.54
RM-N202105
2-(3,5-bis(trifluoromethyl)phenyl)-N-methyl-N-(6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)acetamide

Netupitant Impurity F
Formula: C29H30F6N4O
564.57
RM-N202106
2-(3,5-bis(trifluoromethyl)phenyl)-N-methyl-N-(6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)propanamide

Netupitant Impurity G
Formula: C30H32F6N4O
578.59
RM-N202107
2-(3,5-bis(trifluoromethyl)phenyl)-2-methyl-N-((6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)methyl)propanamide

Netupitant Impurity H
CAS:115309-58-5
Formula: C10H13ClN2O
212.68
RM-N202108
N-(tert-Butyl)-6-chloronicotinamide

NETUPITANT IMPURITY I
CAS:95299-16-4
Formula: C11H8F6O2
286.17
RM-N202109
methyl 2-(3,5-bis(trifluoromethyl)phenyl)acetate

Netupitant Nitroso Impurity 40
Formula: C29H29F6N5O2
593.57
RM-N202140
2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(6-(4-nitrosopiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)propanamide

NETUPITANT-D6
Formula: C30H26D6F6N4O
584.64
RM-N202121
2-(3,5-bis(trifluoromethyl)phenyl)-N-methyl-2-(methyl-d3)-N-(6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)propanamide-3,3,3-d3

NEVIRAPINE EP IMPURITY A
CAS:133627-17-5
Formula: C14H14N4O
254.29
RM-N230001
11-Ethyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

NEVIRAPINE EP IMPURITY B
CAS:287980-84-1
Formula: C12H10N4O
226.24
RM-N230002
4-Methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

NEVIRAPINE EP IMPURITY C
CAS:287980-85-2
Formula: C15H16N4O
268.32
RM-N230003
4-Methyl-11-propyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

NEW RED
CAS:220658-76-4
Formula: C18H15N3O11S3*Na3
545.51*68.97
RG-A262224
5-(Acetylamino)-4-hydroxy-3-[2-(4-sulfophenyl)diazenyl]-2,7-naphthalenedisulfonic acid sodium salt (1:3), 5-(Acetylamino)-4-hydroxy-3-[(4-sulfophenyl)azo]-2,7-naphthalenedisulfonic acid trisodium salt

NH-BIS(PEG4-T-BUTYL ESTER)
CAS:2055041-41-1
Formula: C30H59NO12
625.8
RG-E140351
di-tert-butyl 4,7,10,13,19,22,25,28-octaoxa-16-azahentriacontanedioate

NICARBAZIN IMPURITY 1
CAS:587-90-6
Formula: C13H10N4O5
302.24
RM-N092701
1,3-Bis(4-nitrophenyl)urea

NICARDIPINE D3
CAS:1189945-63-8
Formula: C26H26D3N3O6
482.55
RM-N200462
3-(2-(benzyl(methyl-d3)amino)ethyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

NICARDIPINE HYDROCHLORIDE
CAS:54527-84-3
Formula: C26H29N3O6*HCl
479.53*36.46
RM-N200500
3-(2-(benzyl(methyl)amino)ethyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride

Nicardipine Impurity 101
CAS:142592-15-2
Formula: C17H17NO7
347.32
RM-N200501
dimethyl 5-methyl-3'-nitro-3-oxo-1,2,3,6-tetrahydro-[1,1'-biphenyl]-2,6-dicarboxylate

Nicardipine Impurity 102
Formula: C26H31N3O8
513.55
RM-N200502
1-(2-(benzyl(methyl)amino)ethyl) 5-methyl (E)-2-acetyl-4-(1-aminoethylidene)-2-hydroxy-3-(3-nitrophenyl)pentanedioate

Nicardipine Impurity 103
Formula: C26H30N2O9
514.53
RM-N200503
1-(2-(benzyl(methyl)amino)ethyl) 5-methyl (E)-2-acetyl-2-hydroxy-4-(1-hydroxyethylidene)-3-(3-nitrophenyl)pentanedioate

Nicardipine Impurity 42
Formula: C16H17N3O5
331.32
RM-N200442
methyl 5-carbamoyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate

Nicardipine Impurity 43
Formula: C15H15N3O5
317.3
RM-N200443
5-carbamoyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid

Nicardipine Impurity 44
CAS:101-98-4
Formula: C10H15NO
165.24
RM-N200444
2-(benzyl(methyl)amino)ethan-1-ol

Nicardipine Impurity 46
CAS:2724510-66-9
Formula: C26H29N3O7
495.53
RM-N200446
N-benzyl-2-((5-(methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carbonyl)oxy)-N-methylethan-1-amine oxide

Nicardipine Impurity 47
Formula: C15H17NO3
259.31
RM-N200447
methyl 3'-amino-3-methyl-5-oxo-1,2,5,6-tetrahydro-[1,1'-biphenyl]-2-carboxylate

Nicardipine Impurity 48
Formula: C12H12O3
204.23
RM-N200448
methyl (Z)-2-benzylidene-3-oxobutanoate

Nicardipine Impurity 49
Formula: C12H11NO5
249.22
RM-N200449
methyl (Z)-2-(4-nitrobenzylidene)-3-oxobutanoate

Nicardipine Impurity 50
Formula: C12H10N2O7
294.22
RM-N200450
methyl (Z)-2-(3,5-dinitrobenzylidene)-3-oxobutanoate

Nicardipine Impurity 51
CAS:167963-66-8
Formula: C18H17N3O6
371.35
RM-N200451
5-((2-cyanoethoxy)carbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid

Nicardipine Impurity 52
Formula: C12H13NO6
267.24
RM-N200452
methyl 2-(hydroxy(3-nitrophenyl)methyl)-3-oxobutanoate

Nicardipine Impurity 53
Formula: C15H17NO6
307.3
RM-N200453
methyl 4-acetyl-3-(3-nitrophenyl)-5-oxohexanoate

Nicardipine Impurity 54
CAS:2242606-39-7
Formula: C15H18O4
262.31
RM-N200454
methyl 4-acetyl-5-oxo-3-phenylhexanoate

Nicardipine Impurity 55
CAS:541-50-4
Formula: C4H6O3
102.09
RG-O241505
3-oxobutanoic acid

Nicardipine Impurity 56
Formula: C4H7NO2
101.11
RM-B140444
(Z)-3-aminobut-2-enoic acid

Nicardipine Impurity 60
Formula: C13H12ClNO5
297.69
RM-N200460
2-chloroethyl (E)-2-(3-nitrobenzylidene)-3-oxobutanoate

Nicardipine Impurity 61
Formula: C18H19ClN2O6
394.81
RM-N200461
3-(2-chloroethyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-

Nicardipine Impurity 63
CAS:76093-36-2
Formula: C26H29N3O6
479.53
RM-N200463
3-(2-(benzyl(methyl)amino)ethyl) 5-methyl (S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nicardipine Impurity 64
CAS:76093-35-1
Formula: C26H29N3O6
479.53
RM-N200464
3-(2-(benzyl(methyl)amino)ethyl) 5-methyl (R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nicardipine Impurity 66
Formula: C33H34N4O9
630.65
RM-N200466
1-(2-(benzyl(methyl)amino)ethyl) 5-methyl (Z)-2-acetyl-4-(1-(((E)-3-nitrobenzylidene)amino)ethylidene)-3-(3-nitrophenyl)pentanedioate

Nicardipine Impurity 67
Formula: C33H34N4O9
630.65
RM-N200467
1-(2-(benzyl(methyl)amino)ethyl) 5-methyl (E)-2-acetyl-4-(1-(((Z)-3-nitrobenzylidene)amino)ethylidene)-3-(3-nitrophenyl)pentanedioate

Nicardipine Impurity 68
Formula: C25H28N4O5
464.52
RM-N200468
2-(benzyl(methyl)amino)ethyl 5-carbamoyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate

Nicardipine Impurity 69
Formula: C30H34N4O7
562.62
RM-N200469
2-(benzyl(methyl)amino)ethyl (E)-5-((4-methoxy-4-oxobut-2-en-2-yl)carbamoyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate

Nicardipine Impurity 70
Formula: C12H10N2O7
294.22
RM-N200470
methyl (Z)-2-(2,4-dinitrobenzylidene)-3-oxobutanoate

Nicardipine Impurity 71
Formula: C12H9N3O9
339.22
RM-N200471
methyl (Z)-3-oxo-2-(2,4,6-trinitrobenzylidene)butanoate

Nicardipine Impurity 72
Formula: C20H23NO2
309.41
RM-N200472
N-(3,3-diphenylpropyl)-N-methyl-3-oxobutanamide

Nicardipine Impurity 73
Formula: C8H13ClO3
192.64
RM-N200473
1-chloro-2-methylpropan-2-yl 3-oxobutanoate

Nicardipine Impurity 74
Formula: C8H13ClO3
192.64
RM-N200474
3-chloro-2-methylpropyl 3-oxobutanoate

Nicardipine Impurity 75
Formula: C15H15NO2
241.29
RM-N200475
methyl 2,6-dimethyl-4-phenylnicotinate

Nicardipine Impurity 76
Formula: C15H17NO2
243.31
RM-N200476
methyl 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3-carboxylate

Nicardipine Impurity 77
Formula: C12H13NO5
251.24
RM-N200477
methyl 2-(3-nitrobenzyl)-3-oxobutanoate

Nicardipine Impurity 78
Formula: C8H15ClO
162.66
RM-N200478
3-(3-chloro-2-methylpropoxy)-2-methylprop-1-ene

Nicardipine Impurity 79
Formula: C12H13NO6
267.24
RM-N200479
methyl 2-hydroxy-2-(3-nitrobenzyl)-3-oxobutanoate

Nicardipine Impurity 80
CAS:40641-47-2
Formula: C12H11NO5
249.22
RM-N200480
methyl 2-(4-nitrobenzylidene)-3-oxobutanoate

Nicardipine Impurity 81
Formula: C19H20N2O8
404.38
RM-N200481
3-((5-(methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carbonyl)oxy)propanoic acid

Nicardipine Impurity 82
Formula: C28H30N4O6
518.57
RM-N200482
3-(2-(benzyl(methyl)amino)ethyl) 5-(2-cyanoethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nicardipine Impurity 83
Formula: C21H22N2O10
462.41
RM-N200483
3,3'-((2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarbonyl)bis(oxy))dipropionic acid

Nicardipine Impurity 84
Formula: C26H27N3O7
493.52
RM-N200484
3-((2-(benzyl(methyl)amino)ethoxy)carbonyl)-5-(methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)pyridine 1-oxide

Nicardipine Impurity 85
CAS:75150-43-5
Formula: C19H19N3O6
385.38
RM-N200485
3-(2-cyanoethyl) 5-methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nicardipine Impurity 86
CAS:862889-08-5
Formula: C19H19N3O6
385.38
RM-N200486
3-(2-cyanoethyl) 5-methyl 2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nicardipine Impurity 87
Formula: C37H41N5O12
747.76
RM-N200487
5,5'-dimethyl O'3,O3-((methylazanediyl)bis(ethane-2,1-diyl)) bis(2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate)

Nicardipine Impurity 88
Formula: C35H41N3O8
631.73
RM-N200488
bis(2-(benzyl(methyl)amino)ethyl) 2,4-diacetyl-3-(3-nitrophenyl)pentanedioate

Nicardipine Impurity 89
Formula: C17H21NO3S
319.42
RM-N200489
2-(benzyl(methyl)amino)ethyl 4-methylbenzenesulfonate

Nicardipine Impurity 90
Formula: C14H12N2O5
288.26
RM-N200490
2-cyanoethyl (Z)-2-(2-nitrobenzylidene)-3-oxobutanoate

Nicardipine Impurity 91
Formula: C14H12N2O5
288.26
RM-N200491
2-cyanoethyl (Z)-2-(4-nitrobenzylidene)-3-oxobutanoate

Nicardipine Impurity 92
Formula: C29H35N3O6
521.61
RM-N200492
3-(2-(benzyl(methyl)amino)ethyl) 5-(tert-butyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nicardipine Impurity 95
Formula: C15H15NO5
289.29
RM-N200495
methyl 5-methyl-3'-nitro-3-oxo-1,2,3,4-tetrahydro-[1,1'-biphenyl]-2-carboxylate

Nicardipine Impurity 96
Formula: C17H17NO7
347.32
RM-N200496
dimethyl 2,6-dimethyl-4-(3-nitrophenyl)-4H-pyran-3,5-dicarboxylate

Nicardipine Impurity 97
CAS:27058-15-7
Formula: C17H21NO
255.36
RM-N200497
N-benzyl-2-(benzyloxy)-N-methylethan-1-amine

Nicardipine Impurity 98
CAS:71126-62-0
Formula: C10H15NO
165.24
RM-N200498
2-(benzyloxy)-N-methylethan-1-amine

Nicardipine Impurity 99
Formula: C15H16N4O4
316.32
RM-N200499
2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxamide

Nicardipine Nitroso Impurity 93
Formula: C19H22N4O7
418.41
RM-N200493
3-methyl 5-(2-(methyl(nitroso)amino)ethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nicardipine Nitroso Impurity 94
Formula: C25H26N4O7
494.5
RM-N200494
3-(2-(benzyl(nitroso)amino)ethyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nicardipine USP Related Compound A; Benidipine Impurity N; Lercanidipine Impurity 1; Nimodipine Impurity 7
CAS:74936-72-4
Formula: C16H16N2O6
332.31
RM-N200406
5-(methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid

NICERGOLINE EP IMPURITY A
CAS:38536-28-6
Formula: C24H26ClN3O3
439.93
RM-N091801
((6aR,9R,10aS)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-chloronicotinate

NICERGOLINE EP IMPURITY B
CAS:35264-46-1
Formula: C23H24BrN3O3
470.36
RM-N091802
((6aR,9R,10aS)-10a-methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate

NICERGOLINE EP IMPURITY C
CAS:35155-28-3
Formula: C18H24N2O2
300.4
RM-N091803
((6aR,9R,10aS)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol

Nicergoline EP Impurity C-D3
Formula: C18H21D3N2O2
303.42
RM-N091815
((6aR,9R,10aS)-10a-methoxy-7-methyl-4-(methyl-d3)-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol

NICERGOLINE EP IMPURITY D
CAS:20826-04-4
Formula: C6H4BrNO2
202.01
RM-N091804
5-Bromonicotinic acid

NICERGOLINE EP IMPURITY E
CAS:57935-66-7
Formula: C23H24BrN3O3
470.36
RM-N091805
((6aR,9R,10aS)-10a-hydroxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate

Nicergoline EP Impurity F(Rss)
CAS:58001-19-7
Formula: C24H26BrN3O3
484.39
RM-N091806
((6aR,9S,10aS)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate

NICERGOLINE EP IMPURITY G
CAS:57935-65-6
Formula: C23H24BrN3O2
454.36
RM-N091807
((6aR,9R,10aR)-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate

NICERGOLINE EP IMPURITY H
CAS:192504-81-7
Formula: C23H24BrN3O3
470.36
RM-N091808
((6aR,9R,10aS)-10a-methoxy-4-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate

NICERGOLINE EP IMPURITY I
Formula: C46H46Br2N6O6
938.72
RM-N091809
((6aR,6'aR,9R,9'R,10aS,10'aS)-10a,10'a-dimethoxy-7,7'-dimethyl-4',6a,6',6'a,7,7',8,8',9,9',10,10a,10',10'a-tetradecahydro-6H-[4,5'-biindolo[4,3-fg]quinoline]-9,9'-diyl)bis(methylene) bis(5-bromonicotinate)

NICERGOLINE EP IMPURITY J
Formula: C47H48Br2N6O6
952.73
RM-N091810
((6aR,6'aR,9R,9'R,10aS,10'aS)-10a,10'a-dimethoxy-4',7,7'-trimethyl-4',6a,6',6'a,7,7',8,8',9,9',10,10a,10',10'a-tetradecahydro-6H-[4,5'-biindolo[4,3-fg]quinoline]-9,9'-diyl)bis(methylene) bis(5-bromonicotinate)

NICERGOLINE IMPURITY 11
CAS:35121-60-9
Formula: C17H22N2O2
286.37
RM-N091811
((6aR,9R,10aS)-10a-methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol

Nicergoline Impurity 12
Formula: C17H19D3N2O2
289.39
RM-N091812
((6aR,9R,10aS)-10a-(methoxy-d3)-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol

Nicergoline Impurity 13
CAS:2061916-37-6
Formula: C24H26BrN3O4
500.39
RM-N091813
(6aR,9R,10aS)-9-(((5-bromonicotinoyl)oxy)methyl)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline 7-oxide

Nicergoline Impurity 14
Formula: C17H22N2O2
286.38
RM-N091814
((6aR,9R,10aS)-10a-methoxy-4-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol

Nicergoline Impurity 16
CAS:23495-65-0
Formula: C18H22N2O3
314.39
RM-N091816
methyl (6aR,9R,10aR)-10a-methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate

Nicergoline Impurity 17(Rrr)
CAS:58001-21-1
Formula: C24H26BrN3O3
484.39
RM-N091817
((6aR,9R,10aR)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate

Nicergoline Impurity 18(Rsr)
CAS:58001-20-0
Formula: C24H26BrN3O3
484.39
RM-N091818
((6aR,9S,10aR)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate

Nicergoline Impurity 19
CAS:39620-02-5
Formula: C6H3BrClNO
220.45
RM-N091819
5-Bromonicotinoyl chloride

Nicergoline Impurity 20
Formula: C2313CH23D3BrN3O3
488.4
RM-N091820
((6aR,9R,10aS)-10a-methoxy-4-methyl-7-(methyl-13C-d3)-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate

Nicergoline Impurity 20(Srs)
Formula: C24H26BrN3O3
484.39
RM-N091824
((6aS,9R,10aS)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate

Nicergoline Impurity 21(Nicergoline EP Impurity C-N1-13C-D3)
Formula: C1713CH21D3N2O2
304.41
RM-N091821
((6aR,9R,10aS)-10a-methoxy-7-methyl-4-(methyl-13C-d3)-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol

Nicergoline Impurity 22(Srr)
Formula: C24H26BrN3O3
484.39
RM-N091822
((6aS,9R,10aR)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate

Nicergoline Impurity 23(Ssr)
CAS:2238859-47-5
Formula: C24H26BrN3O3
484.39
RM-N091823
((6aS,9S,10aR)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate

Nicergoline Impurity 25(Sss)
Formula: C24H26BrN3O3
484.39
RM-N091825
((6aS,9S,10aS)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate

Nicergoline Impurity 26
Formula: C19H26N2O2
314.43
RM-N091826
(6aR,9R,10aS)-10a-methoxy-9-(methoxymethyl)-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline

Nicergoline Impurity 27
Formula: C19H26N2O2
314.43
RM-N091827
(6aR,10aS)-10a-methoxy-9-(methoxymethyl)-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline

Nicergoline Impurity 28
Formula: C24H25BrClN3O3
518.84
RM-N091828
((6aR,9R,10aS)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromo-6-chloronicotinate

Nicergoline Impurity 29
Formula: C18H23ClN2O
318.85
RM-N091829
(6aR,9R,10aS)-9-(chloromethyl)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline

Nicergoline Impurity 30
Formula: C24H27Br2N3O2
549.31
RM-N091830
(6aR,9R)-9-(((5-bromonicotinoyl)oxy)methyl)-4,7,7-trimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-7-ium bromide

Nicergoline Impurity 31
CAS:201931-22-8
Formula: C17H22N2O2
286.38
RM-N091831
((6aR,9R,10aR)-10a-methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol

Nicergoline Impurity 33
CAS:40170-12-5
Formula: C17H22N2O
270.38
RM-N091833
((6aR,9R,10aR)-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol

Nicergoline Impurity 34
CAS:7079-87-0
Formula: C16H20N2O2
272.35
RM-N091834
(6aR,9R,10aS)-9-(hydroxymethyl)-7-methyl-6,6a,7,8,9,10-hexahydroindolo[4,3-fg]quinolin-10a(4H)-ol

Nicergoline Impurity 35
Formula: C16H20N2O
256.35
RM-N091835
((6aR,9R,10aR)-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol

Nicergoline Impurity 36
Formula: C46H46Br2N6O6
938.72
RM-N091836
((6aR,6'aR,9R,9'R,10aS,10'aS)-10a,10'a-dimethoxy-7,7'-dimethyl-6a,6'a,7,7',8,8',9,9',10,10a,10',10'a-dodecahydro-6H,6'H-[4,4'-biindolo[4,3-fg]quinoline]-9,9'-diyl)bis(methylene) bis(5-bromonicotinate)

Nicergoline Impurity 37
CAS:78686-77-8
Formula: C7H5BrClNO2
250.48
RM-N091837
Methyl 5-bromo-6-chloronicotinate

Nicergoline Impurity 38
Formula: C24H26BrN3O4
500.39
RM-N091838
3-bromo-5-((((6aR,9R,10aS)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methoxy)carbonyl)pyridine 1-oxide

Nicergoline Impurity 39
Formula: C23H22BrN3O2
452.35
RM-N091839
((6aR,10aR)-4,7-dimethyl-4,6,6a,7,8,10a-hexahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate

Nicergoline Impurity 40
Formula: C24H26BrN3O5
516.39
RM-N091840
(6aR,9R,10aS)-9-(((5-bromo-1-oxidopyridine-3-carbonyl)oxy)methyl)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline 7-oxide

Nicergoline Impurity 42
CAS:23495-64-9
Formula: C18H22N2O3
314.39
RM-N091842
methyl (6aR,9R,10aS)-10a-methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate

Nicergoline Nitroso Impurity 41
Formula: C23H23BrN4O4
499.37
RM-N091841
((6aR,9R,10aS)-10a-methoxy-4-methyl-7-nitroso-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate

Nicergoline(Rrs)
CAS:27848-84-6
Formula: C24H26BrN3O3
484.39
RM-N091800
((6aR,9R,10aS)-10a-Methoxy-4,7-diMethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)Methyl 5-broMonicotinate

NICLOFOLAN
CAS:10331-57-4
Formula: C12H6Cl2N2O6
345.09
RM-N091500
5,5'-dichloro-3,3'-dinitro-[1,1'-biphenyl]-2,2'-diol

NICLOSAMIDE
CAS:50-65-7
Formula: C13H8Cl2N2O4
327.12
RM-N031200
5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide

NICLOSAMIDE IMPURITY 1
CAS:32853-24-0
Formula: C13H9ClN2O4
292.67
RM-N031201
N-(2-Chloro-4-nitrophenyl)-2-hydroxybenzamide

NICLOSAMIDE IMPURITY 2
CAS:16739-21-2
Formula: C13H7Cl3N2O4
361.56
RM-N031202
3,5-Dichloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide

NICLOSAMIDE IMPURITY 3
CAS:16739-20-1
Formula: C13H8Cl2N2O4
327.12
RM-N031203
3-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide

NICLOSAMIDE IMPURITY 4
CAS:4638-49-7
Formula: C13H9ClN2O4
292.67
RM-N031204
5-chloro-2-hydroxy-N-(4-nitrophenyl)benzamide

NICORANDIL
CAS:65141-46-0
Formula: C8H9N3O4
211.17
RM-N031800
2-(nicotinamido)ethyl nitrate

NICORANDIL EP IMPURITY A
CAS:65141-47-1
Formula: C8H9N3O4
211.17
RM-N031801
2-(isonicotinamido)ethyl nitrate

NICORANDIL EP IMPURITY B
CAS:6265-73-2
Formula: C8H10N2O2
166.18
RM-N031832
N-(2-hydroxyethyl)nicotinamide

NICORANDIL EP IMPURITY C
CAS:46053-56-9
Formula: C8H10N2O2
166.18
RM-N031803
2-aminoethyl nicotinate

NICORANDIL EP IMPURITY D
CAS:40055-37-6
Formula: C8H8N2O
148.16
RM-N031804
2-(pyridin-3-yl)-4,5-dihydrooxazole

NICORANDIL IMPURITY 1
CAS:108-89-4
Formula: C6H7N
93.13
RM-N031827
4-Methylpyridine

NICORANDIL IMPURITY 10
CAS:83440-03-3
Formula: C10H12N2O3
208.21
RM-N031836
2-(nicotinamido)ethyl acetate

NICORANDIL IMPURITY 11
CAS:107833-98-7
Formula: C8H9N3O5
227.17
RM-N031837
3-((2-(nitrooxy)ethyl)carbamoyl)pyridine 1-oxide

NICORANDIL IMPURITY 12
CAS:1798026-96-6
Formula: C16H17N5O5
359.34
RM-N031838
2-(N-(2-(nicotinamido)ethyl)nicotinamido)ethyl nitrate

NICORANDIL IMPURITY 13
CAS:2250142-71-1
Formula: C16H18N5O5 I
360.35 126.91
RM-N031839
1-(2-(nicotinamido)ethyl)-3-((2-(nitrooxy)ethyl)carbamoyl)pyridin-1-ium iodide

Nicorandil Impurity 14 (Nicorandil Trimer)
Formula: C24H27N7O6 I2
509.52 253.81
RM-N031840
1-(2-(nicotinamido)ethyl)-3-((2-(3-((2-(nitrooxy)ethyl)carbamoyl)pyridin-1-ium-1-yl)ethyl)carbamoyl)pyridin-1-ium iodide

NICORANDIL IMPURITY 15
Formula: C10H14N2O3
210.23
RM-N031841
N,N-bis(2-hydroxyethyl)nicotinamide

NICORANDIL IMPURITY 16
CAS:1157-74-0
Formula: C10H12N4O7
300.22
RM-N031842
(nicotinoylazanediyl)bis(ethane-2,1-diyl) dinitrate

NICORANDIL IMPURITY 17
CAS:207571-58-2
Formula: C8H8N2O5
212.16
RM-N031843
2-(nitrooxy)ethyl nicotinate

NICORANDIL IMPURITY 18
CAS:113743-17-2
Formula: C8H9N3O5
227.17
RM-N031844
2-(6-hydroxynicotinamido)ethyl nitrate

NICORANDIL IMPURITY 2
CAS:108-99-6
Formula: C6H7N
93.13
RM-N031828
3-Methylpyridine

NICORANDIL IMPURITY 20
CAS:70892-82-9
Formula: C10H14N2O3
210.23
RM-N031846
N,N-bis(2-hydroxyethyl)isonicotinamide

NICORANDIL IMPURITY 21
Formula: C8H9N3O3
195.18
RM-N031847
2-(nicotinamido)ethyl nitrite

NICORANDIL IMPURITY 22
Formula: C32H36N9O7*I3
658.69*380.72
RM-N031848
1-(2-(nicotinamido)ethyl)-3-((2-(3-((2-(3-((2-(nitrooxy)ethyl)carbamoyl)pyridin-1-ium-1-yl)ethyl)carbamoyl)pyridin-1-ium-1-yl)ethyl)carbamoyl)pyridin-1-ium iodide

NICORANDIL IMPURITY 23
Formula: C8H9N3O3
195.18
RM-N031849
2-(nitrosoamino)ethyl nicotinate

NICORANDIL IMPURITY 24
Formula: C16H19N4O3*I
315.35*126.91
RM-N031850
3-((2-hydroxyethyl)carbamoyl)-1-(2-(nicotinamido)ethyl)pyridin-1-ium iodide

NICORANDIL IMPURITY 25
Formula: C16H17IN4O2
424.24
RM-N031851
3-(4,5-dihydrooxazol-2-yl)-1-(2-(nicotinamido)ethyl)pyridin-1-ium iodide

NICORANDIL IMPURITY 26
Formula: C7H6N2O2
150.13
RM-N031852
N-formylnicotinamide

NICORANDIL IMPURITY 27
Formula: C8H9N3O3
195.18
RM-N031853
N-(2-hydroxyethyl)-N-nitrosonicotinamide

NICORANDIL IMPURITY 28
Formula: C3H5NO4
119.08
RM-N031854
nitric propionic anhydride

NICORANDIL IMPURITY 29
CAS:16051-48-2
Formula: C2H5NO4
107.07
RM-N031855
2-hydroxyethyl nitrate

Nicorandil Impurity 3; Nicotinamide EP Impurity A
CAS:59-67-6
Formula: C6H5NO2
123.11
RM-N031829
Nicotinic acid

NICORANDIL IMPURITY 30
Formula: C8H9N3O4
211.17
RM-N031856
N-ethyl-N-(nitrooxy)isonicotinamide

NICORANDIL IMPURITY 31
Formula: C8H9N3O5
227.18
RM-N031857
2-(6-oxo-5,6-dihydropyridine-3-carboxamido)ethyl nitrate

Nicorandil Impurity 32 (Nicorandil Dimer Ii)
Formula: C16H17N5O5
359.34
RM-N031859
N-[2-({N-[2-(nitro-oxy)ethyl]pyridin-3-carboximidoyl}oxy)ethyl]pyridine-3-carboxamide

Nicorandil Impurity 33 (Nicorandil Trimer Ii)
Formula: C24H25N7O6
507.51
RM-N031860
N-{2-[{N-[2-({N-[2-(nitro-oxy)ethyl]pyridin-3-carboximidoyl}oxy)ethyl]pyridin-3-carboximidoyl}oxy]ethyl}pyridine-3-carboxamide

Nicorandil Impurity 34 (Nicorandil Tetramer Ii)
Formula: C32H33N9O7
655.67
RM-N031861
N-{2-[(N-{2-[{N-[2-({N-[2-(nitro-oxy)ethyl]pyridin-3-carboximidoyl}oxy)ethyl]pyridin-3-carboximidoyl}oxy]ethyl}pyridin-3- carboximidoyl)oxy]ethyl}pyridine-3-carboxamide

Nicorandil Impurity 36
CAS:896133-95-2
Formula: C8H10N2O3
182.18
RM-N031863
N-(2-hydroxyethyl)-6-oxo-1,6-dihydropyridine-3-carboxamide

Nicorandil Impurity 37
CAS:1854-30-4
Formula: C4H9NO2
103.12
RM-N031864
2-aminoethyl acetate

Nicorandil Impurity 38
CAS:89166-58-5
Formula: C4H8N2O4
148.12
RM-N031865
2-acetamidoethyl nitrate

Nicorandil Impurity 39
CAS:34104-46-6
Formula: C14H13N3O3
271.28
RM-N031866
2-(nicotinamido)ethyl nicotinate

NICORANDIL IMPURITY 4
CAS:1570-45-2
Formula: C8H9NO2
151.16
RM-N031830
Ethyl isonicotinate

Nicorandil Impurity 41
CAS:14906-63-9
Formula: C8H9NO3
167.16
RM-N031868
3-(ethoxycarbonyl)pyridine 1-oxide

Nicorandil Impurity 42
CAS:67720-36-9
Formula: C8H10N2O3
182.18
RM-N031869
3-((2-hydroxyethyl)carbamoyl)pyridine 1-oxide

Nicorandil Impurity 44
Formula: C16H17N5O5
359.34
RM-N031871
2-(nicotinamido)ethyl (Z)-N-(2-(nitrooxy)ethyl)nicotinimidate

Nicorandil Impurity 47
Formula: C14H13N3O3
271.28
RM-N031874
N-(2-hydroxyethyl)-N-nicotinoylnicotinamide

Nicorandil Impurity 48
Formula: C20H16N4O4
376.37
RM-N031875
2-(N-nicotinoylnicotinamido)ethyl nicotinate

Nicorandil Impurity 49
Formula: C8H9N3O4
211.18
RM-N031876
2-(picolinamido)ethyl nitrate

NICORANDIL IMPURITY 5
CAS:614-18-6
Formula: C8H9NO2
151.16
RM-N031831
Ethyl nicotinate

Nicorandil Impurity 50
Formula: C10H13N3O5
255.23
RM-N031877
2-(N-(2-hydroxyethyl)nicotinamido)ethyl nitrate

Nicorandil Impurity 51
Formula: C4H9N3O4
163.13
RM-N031878
azanediylbis(ethane-2,1-diyl) dinitrite

Nicorandil Impurity 52
Formula: C2H6N2O2
90.08
RM-N031879
2-aminoethyl nitrite

Nicorandil Impurity 53
CAS:16180-96-4
Formula: C6H11NO3
145.16
RM-N031880
N-[2-(Acetyloxy)ethyl]acetamide; 2-acetamidoethyl acetate

Nicorandil Impurity 54
Formula: C16H18N4O3
314.35
RM-N031881
N-(2-hydroxyethyl)-N-(2-(nicotinamido)ethyl)nicotinamide

Nicorandil Impurity 55
CAS:41116-48-7
Formula: C8H10N2O
150.18
RM-N031882
N-ethylisonicotinamide

Nicorandil Impurity 56
CAS:1903-64-6
Formula: C8H10N2O
150.18
RM-N031883
N,N-dimethylisonicotinamide

Nicorandil Impurity 57
CAS:41116-47-6
Formula: C8H10N2O
150.18
RM-N031884
N-ethylpicolinamide

Nicorandil Impurity 58
CAS:14805-91-5
Formula: C8H10N2O
150.18
RM-N031885
N,N-dimethylpicolinamide

Nicorandil Impurity 59
CAS:6972-69-6
Formula: C8H10N2O
150.18
RM-N031886
N,N-Dimethylnicotinamide

Nicorandil Impurity 61
Formula: C8H9N3O3
195.18
RM-N031888
N-(2-hydroxyethyl)-N-nitrosopicolinamide

Nicorandil Impurity 62
Formula: C8H9N3O3
195.18
RM-N031889
2-(nitrosoamino)ethyl picolinate

Nicorandil Impurity 63
CAS:3004558-52-2
Formula: C8H8N4O5
240.18
RM-N031890
2-(N-nitrosonicotinamido)ethyl nitrate

Nicorandil Impurity 64
Formula: C8H8N4O4
224.18
RM-N031891
2-(N-nitrosonicotinamido)ethyl nitrite

Nicorandil Impurity 65
Formula: C16H17N5O5
359.34
RM-N031892
2-(nicotinamido)ethyl (E)-N-(2-(nitrooxy)ethyl)nicotinimidate

Nicorandil Impurity 66
CAS:583-08-4
Formula: C8H8N2O3
180.16
RM-N031894
nicotinoylglycine

Nicorandil Impurity 67
CAS:102062-96-4
Formula: C9H12N2O2
180.21
RM-N031895
N-(2-hydroxyethyl)-N-methylnicotinamide

Nicorandil Impurity 68
CAS:3612-79-1
Formula: C14H12N2O4
272.26
RM-N031896
ethane-1,2-diyl dinicotinate

Nicorandil Impurity 69
CAS:939-53-7
Formula: C8H11N3O
165.2
RM-N031897
N-(2-aminoethyl)nicotinamide

NICORANDIL IMPURITY 7
CAS:6265-74-3
Formula: C8H10N2O2
166.18
RM-N031833
N-(2-Hydroxyethyl)isonicotinamide

Nicorandil Impurity 70
Formula: C8H8N4O7
272.17
RM-N031898
2-(6-hydroxy-N-nitronicotinamido)ethyl nitrate

Nicorandil Impurity 71
CAS:66171-50-4
Formula: C7H7NO3
153.14
RM-N031899
Methyl 6-hydroxynicotinate

Nicorandil Impurity 72
Formula: C24H25N7O6
507.51
RM-N031901
2-(((Z)-(2-(nicotinamido)ethoxy)(pyridin-3-yl)methylene)amino)ethyl (Z)-N-(2-(nitrooxy)ethyl)nicotinimidate

Nicorandil Impurity 73
Formula: C8H10N2O2
166.18
RM-N031902
2-(pyridin-3-yl)oxazolidin-2-ol

Nicorandil Impurity 74
Formula: C16H18N4O3
314.35
RM-N031903
2-(nicotinamido)ethyl N-(2-hydroxyethyl)nicotinimidate

Nicorandil Impurity 75
Formula: C9H10N2O4
210.19
RM-N031904
2-((2-hydroxyethyl)carbamoyl)isonicotinic acid

Nicorandil Impurity 77
Formula: C24H25N7O6
507.51
RM-N031906
2-(((Z)-(2-(nicotinamido)ethoxy)(pyridin-3-yl)methylene)amino)ethyl (E)-N-(2-(nitrooxy)ethyl)nicotinimidate

Nicorandil Impurity 78
Formula: C32H33N9O7
655.67
RM-N031907
2-(((Z)-(2-(nicotinamido)ethoxy)(pyridin-3-yl)methylene)amino)ethyl (Z)-N-(2-((E)-((2-(nitrooxy)ethyl)imino)(pyridin-3-yl)methoxy)ethyl)nicotinimidate

Nicorandil Impurity 79
Formula: C16H18N4O3
314.35
RM-N031908
N,N'-(oxybis(ethane-2,1-diyl))dinicotinamide

NICORANDIL IMPURITY 8
Formula: C8H10N2O2
166.18
RM-N031834
2-aminoethyl isonicotinate

NICORANDIL IMPURITY 9
CAS:54120-68-2
Formula: C8H8N2O
148.16
RM-N031835
2-(pyridin-4-yl)-4,5-dihydrooxazole

NICOTIANAMINE
CAS:34441-14-0
Formula: C12H21N3O6
303.32
RM-N369001
(S)-1-((S)-3-(((S)-3-Amino-3-carboxypropyl)amino)-3-carboxypropyl)azetidine-2-carboxylic acid

NICOTINALDEHYDE
CAS:500-22-1
Formula: C6H5NO
107.11
RG-A261996
Nicotinaldehyde

nicotinaldehyde-2,4,5,6-d4
CAS:258854-80-7
Formula: C6HD4NO
111.14
RG-E140452
nicotinaldehyde-2,4,5,6-d4

NICOTINAMIDE
CAS:98-92-0
Formula: C6H6N2O
122.12
RM-N640900
Niacinamide; Nicotinic acid amide, Pyridine-3-carboxylic acid amide; Vitamin B3; Vitamin PP

NICOTINAMIDE ADENINE DINUCLEOTIDE
CAS:53-84-9
Formula: C21H27N7O14P2
663.43
RM-N031845
1-((2R,3R,4S,5R)-5-((((((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)oxidophosphoryl)oxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-3-carbamoylpyridin-1-ium

NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE
CAS:53-59-8
Formula: C21H28N7O17P3
743.41
RM-N031893
1-((2R,3R,4S,5R)-5-((((((((2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)tetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)oxidophosphoryl)oxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-3-carbamoylpyridin-1-ium

Nicotinamide EP Impurity E
CAS:1986-81-8
Formula: C6H6N2O2
138.12
RM-N640901
3-carbamoylpyridine 1-oxide

Nicotinamide Impurity 3
Formula: C9H12N2O
164.2
RM-N640903
N-ethyl-N-methylnicotinamide

Nicotinamide Impurity 4
CAS:18960-16-2
Formula: C9H12N2O
164.2
RM-N640904
N-isopropylnicotinamide

NICOTINAMIDE MONONUCLEOTIDE
CAS:1094-61-7
Formula: C11H15N2O8P
334.22
RM-N640902
((2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate

Nicotinamide riboside chloride
CAS:23111-00-4
Formula: C11H15N2O5 Cl
255.25 35.45
RG-A263149
3-Carbamoyl-1-((2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium chloride

NICOTINE EP IMPURITY A
CAS:581-49-7
Formula: C10H12N2
160.22
RM-N090301
(S)-1,2,3,6-Tetrahydro-2,3'-Bipyridine

NICOTINE EP IMPURITY B
CAS:487-19-4
Formula: C10H10N2
158.2
RM-N090302
3-(1-methyl-1H-pyrrol-2-yl)pyridine

NICOTINE EP IMPURITY C
CAS:486-56-6
Formula: C10H12N2O
176.22
RM-N090303
(S)-1-methyl-5-(pyridin-3-yl)pyrrolidin-2-one

NICOTINE EP IMPURITY D
CAS:532-12-7
Formula: C9H10N2
146.19
RM-N090304
3-(3,4-Dihydro-2H-pyrrol-5-yl)pyridine

NICOTINE EP IMPURITY E
CAS:491-26-9
Formula: C10H14N2O
178.23
RM-N090305
(2S)-1-methyl-2-(pyridin-3-yl)pyrrolidine 1-oxide

NICOTINE EP IMPURITY F
CAS:494-97-3
Formula: C9H12N2
148.2
RM-N090306
(S)-3-(pyrrolidin-2-yl)pyridine

NICOTINE EP IMPURITY G
CAS:494-52-0
Formula: C10H14N2
162.23
RM-N090307
(S)-3-(piperidin-2-yl)pyridine

NICOTINE IMPURITY 10
CAS:3612-80-4
Formula: C8H9NO3
167.16
RM-N090310
2-hydroxyethyl nicotinate

Nicotine Impurity 11
CAS:152306-59-7
Formula: C16H23N2O6-
339.37
RM-N090313
3,4,5-trihydroxy-6-(3-(1-methylpyrrolidin-2-yl)pyridin-1(2H)-yl)tetrahydro-2H-pyran-2-carboxylate

Nicotine Impurity 12
CAS:125630-26-4
Formula: C11H14N2O
190.25
RM-N090316
(1-methylpyrrolidin-3-yl)(pyridin-3-yl)methanone

Nicotine Impurity 13
CAS:7076-23-5
Formula: C9H12N2
148.21
RM-N090317
(R)-Nornicotine; (+)-Nornicotine; (R)-3-(pyrrolidin-2-yl)pyridine

Nicotine Impurity 14
CAS:494-98-4
Formula: C9H8N2
144.18
RM-N090318
Nornicotyrine; +¦-Nornicotyrine; 3-(1H-pyrrol-2-yl)pyridine

Nicotine Impurity 21
CAS:51020-67-8
Formula: C10H14N2O
178.24
RM-N090321
(1R,2S)-1-methyl-2-(pyridin-3-yl)pyrrolidine 1-oxide

Nicotine Impurity 22
CAS:2743-90-0
Formula: C10H12N2
160.22
RM-N090322
1,2,3,6-Tetrahydro-2,3'-bipyridine

Nicotine Impurity 23
CAS:5746-86-1
Formula: C9H12N2
148.21
RM-N090323
3-(Pyrrolidin-2-yl)pyridine

Nicotine Impurity 24
CAS:36508-80-2
Formula: C10H12N2O2
192.22
RM-N090324
(S)-Cotinine N-oxide; (S)-3-(1-methyl-5-oxopyrrolidin-2-yl)pyridine 1-oxide

NICOTINIC ACID EP IMPURITY A
CAS:3222-47-7
Formula: C7H7NO2
137.14
RM-N032001
6-Methylnicotinic acid

NICOTINIC ACID EP IMPURITY B
CAS:1802-30-8
Formula: C12H8N2O4
244.2
RM-N032002
[2,2'-bipyridine]-5,5'-dicarboxylic acid

Nicotinic Acid EP Impurity C
CAS:104-90-5
Formula: C8H11N
121.18
RM-N032003
5-Ethyl-2-methylpyridine

Nicotinic Acid EP Impurity D
CAS:100-26-5
Formula: C7H5NO4
167.12
RM-N032004
Pyridine-2,5-dicarboxylic acid

NICOTINIC ACID EP IMPURITY E
CAS:55-22-1
Formula: C6H5NO2
123.11
RM-N032005
Isonicotinic acid

Nicotinic Acid EP Impurity F
CAS:2047-49-6
Formula: C6H4N2O4
168.11
RM-N032006
5-Nitronicotinic acid

NICOTINIC ACID EP IMPURITY H
CAS:2530-26-9
Formula: C5H4N2O2
124.1
RM-N032008
3-NITROPYRIDINE

Nicotinic Acid EP Impurity I
CAS:940-06-7
Formula: C5H3N3O4
169.1
RM-N032009
3,5-Dinitropyridine

Nicotinic Acid Impurity 10
CAS:13362-26-0
Formula: C8H10N2O2
166.18
RM-N032010
Ethyl 2-aminonicotinate

NICOTINIC ACID IMPURITY 11
CAS:33545-23-2
Formula: C9H11NO2
165.19
RM-N032011
2-aminoethyl benzoate

NICOTINIC ACID IMPURITY 12
CAS:536-78-7
Formula: C7H9N
107.15
RM-N032012
3-ETHYLPYRIDINE

Nicotinic Acid Impurity 13
CAS:30766-20-2
Formula: C8H10N2O2
166.18
RM-N032013
5-(Dimethylamino)nicotinic acid

NICOTINIC ACID IMPURITY 14
CAS:27828-71-3
Formula: C6H5NO3
139.11
RM-N032014
5-HYDROXYNICOTINIC ACID

NICOTINIC ACID IMPURITY 15
CAS:1369121-79-8
Formula: C8H10N2O2
166.18
RM-N032015
5-(ethylamino)nicotinic acid

NICOTINIC ACID IMPURITY 16
CAS:91702-88-4
Formula: C7H8N2O2
152.15
RM-N032016
5-(Methylamino)nicotinic acid

NICOTINIC ANHYDRIDE
CAS:16837-38-0
Formula: C12H8N2O3
228.21
RG-A261945
Nicotinic Anhydride

NICOTINOYL CHLORIDE
CAS:10400-19-8
Formula: C6H4ClNO
141.55
RG-A263029
nicotinoyl chloride

NIFEDIPINE EP IMPURITY A
CAS:67035-22-7
Formula: C17H16N2O6
344.32
RM-N060401
Dimethyl 4-(2-nitrophenyl)-2,6-dimethylpyridine-3,5-dicarboxylate

NIFEDIPINE EP IMPURITY B
CAS:50428-14-3
Formula: C17H16N2O5
328.32
RM-N060402
Dimethyl 4-(2-nitrosophenyl)-2,6-dimethylpyridine-3,5-dicarboxylate

NIFEDIPINE EP IMPURITY C
CAS:39562-27-1
Formula: C12H11NO5
249.22
RM-N060403
methyl 2-(2-nitrobenzylidene)-3-oxobutanoate

NIFEDIPINE IMPURITY 10
CAS:34785-00-7
Formula: C16H12N2O6
328.28
RM-N060436
methyl 2-methyl-4-(3-nitrophenyl)-5-oxo-5,7-dihydrofuro[3,4-b]pyridine-3-carboxylate

NIFEDIPINE IMPURITY 11
Formula: C12H14N2O4
250.25
RM-N060437
(Z)-methyl 3-amino-2-(3-nitrobenzylidene)butanoate

NIFEDIPINE IMPURITY 12
CAS:74378-10-2
Formula: C15H14N2O6
318.28
RM-N060438
2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid

NIFEDIPINE IMPURITY 13
Formula: C18H16N4O6
384.34
RM-N060439
methyl 2,4-bis(2-nitrophenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate

NIFEDIPINE IMPURITY 2
CAS:80742-11-6
Formula: C19H18N4O6
398.37
RM-N060428
methyl (2S,4S)-6-methyl-2,4-bis(2-nitrophenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate

NIFEDIPINE IMPURITY 3
CAS:87625-92-1
Formula: C15H15NO5
289.28
RM-N060429
methyl 3-methyl-3'-nitro-5-oxo-1,2,5,6-tetrahydro-[1,1'-biphenyl]-2-carboxylate

NIFEDIPINE IMPURITY 4
CAS:10323-98-5
Formula: C13H13NO3
231.25
RM-N060430
5-methyl-3'-nitro-1,6-dihydro-[1,1'-biphenyl]-3(2H)-one

Nifedipine Impurity 40
Formula: C12H14N2O4
250.25
RM-N060440
(Z)-methyl 3-amino-2-(2-nitrobenzylidene)butanoate

Nifedipine Impurity 41
Formula: C19H18N4O6
398.37
RM-N060441
methyl (2R,4S)-6-methyl-2,4-bis(2-nitrophenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Nifedipine Impurity 42
Formula: C19H18N4O7
414.37
RM-N060442
methyl 6-methyl-2,4-bis(2-nitrophenyl)-1,2,3,4-tetrahydropyrimidine-5-carboperoxoate

Nifedipine Impurity 43
Formula: C18H20N2O6
360.36
RM-N060443
5-(methoxycarbonyl)-1,2,6-trimethyl-4-(3-methyl-2-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid

NIFEDIPINE IMPURITY 44
CAS:49838-51-9
Formula: C9H11NO4
197.19
RM-N060444
1,3,5-trimethoxy-2-nitrosobenzene

Nifedipine Impurity 45
Formula: C9H9N3O6
255.18
RM-N060445
1,3,5-trimethoxy-2,4,6-trinitrosobenzene

NIFEDIPINE IMPURITY 46
CAS:111304-29-1
Formula: C12H11NO5
249.22
RM-N060446
(E)-methyl 2-(2-nitrobenzylidene)-3-oxobutanoate

Nifedipine Impurity 47
CAS:76258-20-3
Formula: C17H16N2O6
344.32
RM-N060447
Dimethyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate

NIFEDIPINE IMPURITY 48
CAS:34783-31-8
Formula: C16H14N2O7
346.29
RM-N060448
2-(Hydroxymethyl)-5-(methoxycarbonyl)-6-methyl-4-(2-nitrophenyl)nicotinic acid

Nifedipine Impurity 49
CAS:167710-84-1
Formula: C17H18N2O5
330.34
RM-N060449
dimethyl 2,6-dimethyl-4-(2-nitrosophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

NIFEDIPINE IMPURITY 5
CAS:2469735-68-8
Formula: C15H15NO5
289.28
RM-N060431
methyl 5-methyl-3'-nitro-3-oxo-1,2,3,6-tetrahydro-[1,1'-biphenyl]-2-carboxylate

Nifedipine Impurity 50
Formula: C11H15NO4
225.24
RM-N060450
dimethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Nifedipine Impurity 51
Formula: C17H17BrN2O6
425.23
RM-N060451
dimethyl 4-(2-bromo-6-nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Nifedipine Impurity 52
Formula: C17H17BrN2O6
425.23
RM-N060452
dimethyl 4-(4-bromo-2-nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Nifedipine Impurity 53
Formula: C16H12N2O6
328.28
RM-N060453
Methyl 2-methyl-4-(2-nitrophenyl)-5-oxo-5,7-dihydrofuro[3,4-b]pyridine-3-carboxylate

Nifedipine Impurity 54
Formula: C15H16N4O4
316.31
RM-N060454
2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxamide

Nifedipine Impurity 55
CAS:2469555-30-2
Formula: C15H17NO6
307.3
RM-N060455
methyl 2-acetyl-3-(3-nitrophenyl)-5-oxohexanoate

NIFEDIPINE IMPURITY 56
CAS:111304-31-5
Formula: C12H11NO5
249.22
RM-N060456
(Z)-methyl 2-(2-nitrobenzylidene)-3-oxobutanoate

Nifedipine Impurity 57
Formula: C15H15NO5
289.29
RM-N060457
2-(3-methyl-3'-nitro-5-oxo-1,2,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)acetic acid

Nifedipine Impurity 58
Formula: C15H15NO5
289.29
RM-N060458
2-(5-methyl-3'-nitro-3-oxo-1,2,3,6-tetrahydro-[1,1'-biphenyl]-2-yl)acetic acid

Nifedipine Impurity 59
CAS:80742-13-8
Formula: C19H18N4O6
398.38
RM-N060459
methyl (2R,4S)-6-methyl-2,4-bis(2-nitrophenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate

NIFEDIPINE IMPURITY 6
CAS:88434-69-9
Formula: C17H16N2O7
360.32
RM-N060432
3,5-bis(methoxycarbonyl)-2,6-dimethyl-4-(2-nitrophenyl)pyridine 1-oxide

Nifedipine Impurity 60
Formula: C17H19NO8
365.34
RM-N060460
dimethyl 2,4-diacetyl-3-(2-nitrophenyl)pentanedioate

Nifedipine Impurity 62
CAS:65962-15-4
Formula: C7H5Br2NO2
294.93
RM-N060462
1-(Dibromomethyl)-2-nitrobenzene

Nifedipine Impurity 63
CAS:145655-13-6
Formula: C17H16N2O7
360.32
RM-N060463
dimethyl 2-(hydroxymethyl)-6-methyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate

Nifedipine Impurity 64
Formula: C12H11NO5
249.22
RM-N060464
methyl (Z)-5-(3-nitrophenyl)-3-oxopent-4-enoate

Nifedipine Impurity 65
Formula: C19H14N2O7
382.33
RM-N060465
methyl (Z)-2-((E)-3-nitrobenzylidene)-5-(3-nitrophenyl)-3-oxopent-4-enoate

Nifedipine Impurity 66
CAS:73372-63-1
Formula: C16H14N2O6
330.3
RM-N060466
5-(methoxycarbonyl)-2,6-dimethyl-4-(2-nitrophenyl)nicotinic acid

Nifedipine Impurity 67
CAS:88434-67-7
Formula: C15H12N2O6
316.27
RM-N060467
2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylic acid

Nifedipine Impurity 68
Formula: C13H13NO3
231.25
RM-N060468
5-methyl-2'-nitro-1,6-dihydro-[1,1'-biphenyl]-3(2H)-one

Nifedipine Impurity 69
Formula: C15H15NO5
289.29
RM-N060469
methyl 5-methyl-2'-nitro-3-oxo-1,2,3,6-tetrahydro-[1,1'-biphenyl]-2-carboxylate

NIFEDIPINE IMPURITY 7 (MIXTURE OF CIS AND TRANS ISOMERS)
CAS:108139-78-2
Formula: C19H18N4O6
398.38
RM-N060433
methyl 6-methyl-2,4-bis(2-nitrophenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Nifedipine Impurity 70
Formula: C24H27N5O7
497.51
RM-N060470
methyl (E)-3-(5-(((E)-4-amino-4-oxobut-2-en-2-yl)carbamoyl)-2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3-carboxamido)but-2-enoate

Nifedipine Impurity 71
CAS:100-11-8
Formula: C7H6BrNO2
216.03
RM-N060471
1-(bromomethyl)-4-nitrobenzene

Nifedipine Impurity 73
CAS:108139-80-6
Formula: C17H18N2O6
346.34
RM-N060473
dimethyl 4,6-dimethyl-2-(2-nitrophenyl)-1,2-dihydropyridine-3,5-dicarboxylate

NIFEDIPINE IMPURITY 8
CAS:15846-25-0
Formula: C4H8N2O
100.12
RM-N060434
3-aminobut-2-enamide

NIFEDIPINE IMPURITY 9
CAS:21829-26-5
Formula: C19H22N2O6
374.39
RM-N060435
diethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nifedipine Impurity E
CAS:114709-68-1
Formula: C16H17N3O5
331.32
RM-N060405
5-(Aminocarbonyl)-1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3-pyridinecarboxylic Acid Methyl Ester, Nifedipine Impurity 1

NIFEDIPINE-D6
Formula: C17H12D6N2O6
352.37
RM-N060427
Nifedipine-d6

Nifedipine; Benidipine Impurity G; Nisoldipine Impurity A
CAS:21829-25-4
Formula: C17H18N2O6
346.33
RM-N060400
Dimethyl 1,4-dihydro-2,6-dimethyl-4-(o-nitrophenyl)-3,5-pyridinedicarboxylate

NIFEKALANT
CAS:130636-43-0
Formula: C19H27N5O5
405.46
RM-N163000
6-((2-((2-hydroxyethyl)(3-(4-nitrophenyl)propyl)amino)ethyl)amino)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione

Nifekalant Impurity 1
CAS:107324-93-6
Formula: C9H8ClNO3
213.62
RM-N163001
3-(4-nitrophenyl)propanoyl chloride

Nifekalant Impurity 10
Formula: C22H30N4O5
430.51
RM-N163010
N,N'-(oxybis(ethane-2,1-diyl))bis(3-(4-nitrophenyl)propan-1-amine)

Nifekalant Impurity 11
CAS:901571-19-5
Formula: C13H15N3O4S
309.34
RM-N163011
N-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-4-methylbenzenesulfonamide

Nifekalant Impurity 12
Formula: C13H15N3O5S
325.34
RM-N163012
2-((2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino)ethyl 4-methylbenzenesulfonate

Nifekalant Impurity 13
Formula: C24H29N3O8S2
551.63
RM-N163013
((1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)azanediyl)bis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate)

Nifekalant Impurity 14
CAS:130634-04-7
Formula: C15H19N3O5S
353.39
RM-N163014
2-((1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino)ethyl 4-methylbenzenesulfonate

Nifekalant Impurity 15
Formula: C13H21N3O3
267.33
RM-N163015
2-((2-aminoethyl)(3-(4-nitrophenyl)propyl)amino)ethan-1-ol

Nifekalant Impurity 16
Formula: C16H23N3O6
353.38
RM-N163016
3-((2-((2-hydroxyethyl)(3-(4-nitrophenyl)propyl)amino)ethyl)amino)-3-oxopropanoic acid

Nifekalant Impurity 17
CAS:130636-95-2
Formula: C10H18N4O3
242.28
RM-N163017
6-((2-((2-hydroxyethyl)amino)ethyl)amino)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione

Nifekalant Impurity 18
Formula: C19H27N5O6
421.45
RM-N163018
N-(2-((1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino)ethyl)-N-(2-hydroxyethyl)-3-(4-nitrophenyl)propan-1-amine oxide

Nifekalant Impurity 2
CAS:130637-01-3
Formula: C11H14N2O4
238.24
RM-N163002
N-(2-hydroxyethyl)-3-(4-nitrophenyl)propanamide

Nifekalant Impurity 3
CAS:857768-59-3
Formula: C11H14N2O5
254.24
RM-N163003
3-hydroxy-N-(2-hydroxyethyl)-3-(4-nitrophenyl)propanamide

Nifekalant Impurity 4
Formula: C11H14N2O4
238.24
RM-N163004
N-(2-hydroxyethyl)-3-(2-nitrophenyl)propanamide

Nifekalant Impurity 5
CAS:2071357-57-6
Formula: C11H14N2O4
238.24
RM-N163005
N-(2-hydroxyethyl)-3-(3-nitrophenyl)propanamide

Nifekalant Impurity 6
CAS:51816-46-7
Formula: C11H15NO2
193.25
RM-N163006
N-(2-hydroxyethyl)-3-phenylpropanamide

Nifekalant Impurity 7
Formula: C13H18N2O5
282.3
RM-N163007
N,N-bis(2-hydroxyethyl)-3-(4-nitrophenyl)propanamide

Nifekalant Impurity 8
Formula: C13H16N2O5
280.28
RM-N163008
2-(3-(4-nitrophenyl)propanamido)ethyl acetate

Nifekalant Impurity 9
Formula: C13H18N2O4
266.3
RM-N163009
N-(2-ethoxyethyl)-3-(4-nitrophenyl)propanamide

NIFLUMIC ACID
CAS:4394-00-7
Formula: C13H9F3N2O2
282.22
RM-N090700
2-((3-(trifluoromethyl)phenyl)amino)nicotinic acid

NIFLUMIC ACID EP IMPURITY B
Formula: C13H9F3N2O2
282.22
RM-N090702
2-hydroxy-N-(3-(trifluoromethyl)phenyl)nicotinamide

NIFLUMIC ACID EP IMPURITY E
Formula: C13H9F3N2O2
282.22
RM-N090705
6-((3-(trifluoromethyl)phenyl)amino)nicotinic acid

NIFLUMIC ACID EP IMPURITY F
Formula: C14H11F3N2O2
296.24
RM-N090706
methyl 2-((3-(trifluoromethyl)phenyl)amino)nicotinate

NIFURALDEZONE
CAS:3270-71-1
Formula: C7H6N4O5
226.15
RG-A262384
Furamazone; Framazone; 2-(2-((5-nitrofuran-2-yl)methylene)hydrazineyl)-2-oxoacetamide

NIFURATEL
CAS:4936-47-4
Formula: C10H11N3O5S
285.28
RM-N131100
5-((methylthio)methyl)-3-(((5-nitrofuran-2-yl)methylene)amino)oxazolidin-2-one

Nifuratel Impurity 13 (Homo Nifuratel)
Formula: C10H11N3O5S
285.28
RM-N131113
(E)-5-(methylthio)-3-(((5-nitrofuran-2-yl)methylene)amino)-1,3-oxazinan-2-one

NIFURATEL IMPURITY 14
CAS:65019-14-9
Formula: C5H3NO4
141.08
RM-N131114
3-nitrofuran-2-carbaldehyde

NIFURATEL IMPURITY 15
CAS:57500-49-9
Formula: C5H3NO4
141.08
RM-N131115
4-nitrofuran-2-carbaldehyde

NIFURATEL IMPURITY 16
CAS:5407-68-1
Formula: C7H7NO5
185.13
RM-N131116
(5-nitrofuran-2-yl)methyl acetate

NIFURATEL IMPURITY 17
Formula: C8H9NO5
199.16
RM-N131117
(5-nitrofuran-2-yl)methyl propionate

NIFURATEL IMPURITY 18
CAS:3455-50-3
Formula: C9H13NO5
215.2
RM-N131118
2-(diethoxymethyl)-5-nitrofuran

NIFURATEL IMPURITY 19
Formula: C11H8N4O5
276.21
RM-N131119
(1E,2E)-1-((4-nitrocyclopenta-1,3-dien-1-yl)methylene)-2-((5-nitrofuran-2-yl)methylene)hydrazine

NIFURATEL IMPURITY 20
Formula: C10H11N3O6S
301.28
RM-N131120
(Z)-5-((methylthio)methyl)-N-((5-nitrofuran-2-yl)methylene)-2-oxooxazolidin-3-amine oxide

NIFURATEL IMPURITY 21
Formula: C9H9NO7
243.17
RM-N131121
(4-nitrofuran-2-yl)methylene diacetate

NIFURATEL IMPURITY 22
Formula: C9H9NO7
243.17
RM-N131122
(3-nitrofuran-2-yl)methylene diacetate

Nifuratel Impurity 24
Formula: C5H10N2O3S
178.21
RM-N131124
3-amino-5-((methylsulfinyl)methyl)oxazolidin-2-one

NIFURATEL IMPURITY 25
Formula: C10H15N3O6S
305.31
RM-N131125
(Z)-5-((methylthio)methyl)-N-((5-nitrotetrahydrofuran-2-yl)methylene)-2-oxooxazolidin-3-amine oxide

NIFURATEL IMPURITY 26
CAS:22551-26-4
Formula: C4H10O2S
122.19
RM-N131126
3-(methylthio)propane-1,2-diol

NIFURATEL IMPURITY 27
Formula: C5H10N2O2S
162.21
RM-N131127
3-amino-4-((methylthio)methyl)oxazolidin-2-one

NIFURATEL IMPURITY 28
Formula: C5H10N2O2S
162.21
RM-N131128
6-((methylthio)methyl)-1,3,4-oxadiazinan-2-one

NIFURATEL IMPURITY 29
Formula: C5H10N2O2S
162.21
RM-N131129
5-((methylthio)methyl)-1,3,4-oxadiazinan-2-one

NIFURATEL IMPURITY 30
CAS:2493-04-1
Formula: C5H5NO4
143.1
RM-N131130
(5-Nitrofuran-2-yl)methanol

NIFURATEL IMPURITY 31
Formula: C4H12N2OS
136.22
RM-N131131
3-hydrazinyl-2-(methylthio)propan-1-ol

NIFURATEL IMPURITY 32
Formula: C7H12N2O3S
204.24
RM-N131132
N-(5-((methylthio)methyl)-2-oxooxazolidin-3-yl)acetamide

NIFURATEL IMPURITY 33
CAS:859445-34-4
Formula: C9H9NO7
243.17
RM-N131133
(5-nitrofuran-3-yl)methylene diacetate

NIFURATEL IMPURITY 34
CAS:41359-15-3
Formula: C9H9N3O6
255.19
RM-N131134
5-(hydroxymethyl)-3-(((5-nitrofuran-2-yl)methylene)amino)oxazolidin-2-one

NIFURATEL IMPURITY 35
Formula: C12H15NO8
301.25
RM-N131135
(5-nitro-2-(2-oxopropyl)-2,5-dihydrofuran-2-yl)methylene diacetate

NIFURATEL IMPURITY 36
CAS:5904-70-1
Formula: C11H13NO9
303.22
RM-N131136
(2-acetoxy-5-nitro-2,5-dihydrofuran-2-yl)methylene diacetate

NIFURATEL IMPURITY 37
Formula: C9H9NO7
243.17
RM-N131137
dimethyl 2-(5-nitrofuran-2-yl)malonate

Nifuratel Impurity 38
Formula: C10H11N3O6S
301.27
RM-N131138
(E)-5-((methylsulfinyl)methyl)-3-(((5-nitrofuran-2-yl)methylene)amino)oxazolidin-2-one

Nifuratel Impurity 39
Formula: C10H11N3O5S
285.27
RM-N131139
(E)-6-(methylthio)-3-(((5-nitrofuran-2-yl)methylene)amino)-1,3-oxazinan-2-one

Nifuratel Impurity 40 ((E)-Nifuratel)
CAS:1428630-33-4
Formula: C10H11N3O5S
285.27
RM-N131140
(E)-5-((methylthio)methyl)-3-(((5-nitrofuran-2-yl)methylene)amino)oxazolidin-2-one

NIFURATEL IMPURITY A
Formula: C10H11N3O6S
301.28
RM-N131101
N-(5-((methylthio)methyl)-2-oxooxazolidin-3-yl)-5-nitrofuran-2-carboxamide

NIFURATEL IMPURITY B
CAS:736-53-8
Formula: C10H6N4O6
278.18
RM-N131102
1,2-bis((5-Nitrofuran-2-yl)methylene)hydrazine

Nifuratel Impurity C; Nifuroxazide EP Impurity C
CAS:92-55-7
Formula: C9H9NO7
243.17
RM-N131103
(5-nitrofuran-2-yl)methylene diacetate

NIFURATEL IMPURITY D
CAS:25517-72-0
Formula: C5H10N2O2S
162.21
RM-N131104
3-amino-5-((methylthio)methyl)oxazolidin-2-one

Nifuratel Impurity E
Formula: C9H9N3O5S
271.25
RM-N131105
5-(mercaptomethyl)-3-(((5-nitrofuran-2-yl)methylene)amino)oxazolidin-2-one

NIFURATEL IMPURITY F
CAS:1445990-09-9
Formula: C10H11N3O6S
301.28
RM-N131106
5-((methylsulfinyl)methyl)-3-(((5-nitrofuran-2-yl)methylene)amino)oxazolidin-2-one

NIFURATEL IMPURITY G
CAS:45378-62-9
Formula: C4H8OS
104.17
RM-N131107
2-((methylthio)methyl)oxirane

NIFURATEL IMPURITY H
CAS:14359-97-8
Formula: C4H12N2OS
136.22
RM-N131108
1-Hydrazinyl-3-(methylthio)propan-2-ol

Nifuratel Impurity I
Formula: C9H13N3O4S
259.28
RM-N131109
(E)-1-(methylthio)-3-(2-((5-nitrofuran-2-yl)methylene)hydrazinyl)propan-2-ol

Nifuratel Impurity J
Formula: C9H9N3O6
255.18
RM-N131110
(E)-5-(hydroxymethyl)-3-(((5-nitrofuran-2-yl)methylene)amino)oxazolidin-2-one

Nifuratel Impurity K
Formula: C6H5N3O4
183.12
RM-N131111
(E)-N'-((5-nitrofuran-2-yl)methylene)formohydrazide

NIFUROXAZIDE
CAS:965-52-6
Formula: C12H9N3O5
275.22
RM-N092100
(E)-4-Hydroxy-N'-((5-nitrofuran-2-yl)methylene)benzohydrazide

NIFUROXAZIDE EP IMPURITY A
CAS:5351-23-5
Formula: C7H8N2O2
152.15
RM-N092101
4-hydroxybenzohydrazide

NIFUROXAZIDE EP IMPURITY D
CAS:112537-96-9
Formula: C10H6N4O6
278.18
RM-N092104
(1E,2E)-1,2-Bis((5-nitrofuran-2-yl)methylene)hydrazine

NIFUROXAZIDE EP IMPURITY E
Formula: C12H9N3O5
275.22
RM-N092105
(Z)-4-hydroxy-N'-((5-nitrofuran-2-yl)methylene)benzohydrazide

Nifuroxazide Impurity 6
CAS:936-02-7
Formula: C7H8N2O2
152.15
RM-N092106
Salicyloyl hydrazide; Salicylic acid, hydrazide; 2-hydroxybenzohydrazide

NIFURPIRINOL
CAS:13411-16-0
Formula: C12H10N2O4
246.22
RM-N245000
(6-(2-(5-nitrofuran-2-yl)vinyl)pyridin-2-yl)methanol

NIFURPRAZINE
CAS:1614-20-6
Formula: C10H8N4O3
232.2
RM-N131112
(E)-6-(2-(5-nitrofuran-2-yl)vinyl)pyridazin-3-amine

NIKETHAMIDE
CAS:59-26-7
Formula: C10H14N2O
178.23
RM-N091100
N,N-Diethylnicotinamide

NIKETHAMIDE IMPURITY 1
CAS:7606-13-5
Formula: C10H14N2O
178.23
RM-N091101
N,N-diethylpicolinamide

NIKETHAMIDE IMPURITY 2
CAS:20165-96-2
Formula: C10H14N2O2
194.23
RM-N091102
3-(diethylcarbamoyl)pyridine 1-oxide

NIKETHAMIDE IMPURITY 3
CAS:68254-63-7
Formula: C8H10N2O2
166.18
RM-N091103
3-(ethylcarbamoyl)pyridine 1-oxide

Nikethamide Impurity 4
CAS:530-40-5
Formula: C10H14N2O
178.24
RM-N091104
N,N-diethylisonicotinamide

Nikethamide Impurity 5
CAS:51581-40-9
Formula: C10H14N2O2
194.23
RM-N091105
pyridin-3-yl diethylcarbamate

Nikkomycin Impurity 2
CAS:1217466-85-7
Formula: C20H25N5O10
495.45
RM-N132702
(R)-2-((2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanamido)-2-((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)acetic acid

NILOTINIB
CAS:641571-10-0
Formula: C28H22F3N7O
529.52
RM-N091200
4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide

NILOTINIB IMPURITY 1
CAS:1025716-99-7
Formula: C10H14N4O5
270.24
RM-N091201
methyl 3-guanidino-4-methylbenzoate nitrate

NILOTINIB IMPURITY 10
CAS:1246817-85-5
Formula: C28H22F3N7O2
545.52
RM-N091210
3-(2-((2-methyl-5-((3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)carbamoyl)phenyl)amino)pyrimidin-4-yl)pyridine 1-oxide

NILOTINIB IMPURITY 11
CAS:851137-91-2
Formula: C17H15N5O
305.33
RM-N091211
4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide

NILOTINIB IMPURITY 12
CAS:915711-42-1
Formula: C19H17F3N4O
374.36
RM-N091212
3-amino-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide

NILOTINIB IMPURITY 13
CAS:641571-12-2
Formula: C12H8F3N3
251.21
RM-N091213
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzonitrile

NILOTINIB IMPURITY 14
CAS:2469039-94-7
Formula: C28H21ClF3N7O
563.96
RM-N091214
3-((5-chloro-4-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide

NILOTINIB IMPURITY 15
Formula: C9H11N3O2 HCl
193.20 36.46
RM-N091215
3-guanidino-4-methylbenzoic acid hydrochloride

NILOTINIB IMPURITY 16
CAS:41574-91-8
Formula: C9H12N2O2
180.2
RM-N091216
methyl 3,5-diamino-4-methylbenzoate

NILOTINIB IMPURITY 17
CAS:18595-17-0
Formula: C9H11NO2
165.19
RM-N091217
Methyl 2-amino-4-methylbenzoate

NILOTINIB IMPURITY 18
CAS:916975-92-3
Formula: C11H8F3N3O2
271.2
RM-N091218
4-methyl-1-(3-nitro-5-(trifluoromethyl)phenyl)-1H-imidazole

NILOTINIB IMPURITY 19
CAS:943320-48-7
Formula: C10H8F3N3
227.19
RM-N091219
3-(1H-imidazol-1-yl)-5-(trifluoromethyl)aniline

NILOTINIB IMPURITY 2
CAS:641569-94-0
Formula: C17H14N4O2
306.32
RM-N091202
4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoic acid

NILOTINIB IMPURITY 20
CAS:2119583-27-4
Formula: C12H12F3N3
255.24
RM-N091220
3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline

NILOTINIB IMPURITY 21
Formula: C12H12F3N3
255.24
RM-N091221
3-(2,4-dimethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline

NILOTINIB IMPURITY 22
Formula: C10H13N3O2
207.23
RM-N091222
methyl 2-guanidino-4-methylbenzoate

NILOTINIB IMPURITY 23
Formula: C18H16N4O2
320.35
RM-N091223
methyl 4-methyl-3-((4-(pyridin-2-yl)pyrimidin-2-yl)amino)benzoate

NILOTINIB IMPURITY 24
Formula: C18H16N4O2
320.35
RM-N091224
methyl 4-methyl-3-((4-(pyridin-4-yl)pyrimidin-2-yl)amino)benzoate

NILOTINIB IMPURITY 25
Formula: C18H16N4O2
320.35
RM-N091225
methyl 4-methyl-2-((5-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate

NILOTINIB IMPURITY 26
Formula: C17H14N4O2
306.32
RM-N091226
4-methyl-3-((4-(pyridin-2-yl)pyrimidin-2-yl)amino)benzoic acid

NILOTINIB IMPURITY 27
Formula: C17H14N4O2
306.32
RM-N091227
4-methyl-3-((4-(pyridin-4-yl)pyrimidin-2-yl)amino)benzoic acid

NILOTINIB IMPURITY 28
CAS:2119583-25-2
Formula: C29H24F3N7O
543.54
RM-N091228
N-(3-(2,4-dimethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide

NILOTINIB IMPURITY 29
Formula: C27H23N7O2
477.52
RM-N091229
3-(2-((2-methyl-5-((3-(4-methyl-1H-imidazol-1-yl)phenyl)carbamoyl)phenyl)amino)pyrimidin-4-yl)pyridine 1-oxide

NILOTINIB IMPURITY 3
CAS:641571-16-6
Formula: C11H10F3N3
241.21
RM-N091203
3-(5-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline

NILOTINIB IMPURITY 30
Formula: C27H23N7O2
477.52
RM-N091230
4-methyl-1-(3-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamido)phenyl)-1H-imidazole 3-oxide

NILOTINIB IMPURITY 31
Formula: C28H22F3N7O
529.52
RM-N091231
4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-2-yl)pyrimidin-2-yl)amino)benzamide

NILOTINIB IMPURITY 32
Formula: C28H22F3N7O
529.52
RM-N091232
4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-4-yl)pyrimidin-2-yl)amino)benzamide

NILOTINIB IMPURITY 33
Formula: C28H22F3N7O
529.52
RM-N091233
4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-2-((5-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide

Nilotinib Impurity 34
Formula: C17H14N4O2
306.32
RM-N091234
4-methyl-2-((5-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoic acid

NILOTINIB IMPURITY 35
CAS:641569-95-1
Formula: C11H15N3O2
221.26
RM-N091235
ethyl 3-guanidino-4-methylbenzoate

Nilotinib Impurity 36
Formula: C17H15N5O2
321.33
RM-N091236
3-((4-amino-6-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-methylbenzoic acid

Nilotinib Impurity 37
Formula: C17H15N5O2
321.33
RM-N091237
3-amino-4-methyl-5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoic acid

Nilotinib Impurity 39
Formula: C9H11N3O2
193.21
RM-N091239
2-guanidino-4-methylbenzoic acid

NILOTINIB IMPURITY 4
CAS:641569-97-3
Formula: C19H18N4O2
334.37
RM-N091204
ethyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate

Nilotinib Impurity 40
CAS:641570-89-0
Formula: C11H10F3N3
241.22
RM-N091240
4-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)aniline

Nilotinib Impurity 41
Formula: C11H10F3N3
241.22
RM-N091241
2-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline

Nilotinib Impurity 42
Formula: C11H15N3O2
221.26
RM-N091242
ethyl 2-guanidino-4-methylbenzoate

Nilotinib Impurity 43
CAS:18595-18-1
Formula: C9H11NO2
165.19
RG-M052027
Methyl 3-amino-4-methylbenzoate

Nilotinib Impurity 44
CAS:917392-54-2
Formula: C18H16N4O2
320.35
RG-M052088
Methyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate

Nilotinib Impurity 45
CAS:41191-92-8
Formula: C10H13NO2
179.22
RM-N091245
Ethyl 3-amino-4-methylbenzoate

Nilotinib Impurity 46
CAS:2458-12-0
Formula: C8H9NO2
151.16
RG-M052030
3-Amino-4-methylbenzoic acid

Nilotinib Impurity 47
CAS:641571-05-3
Formula: C28H22F3N7O
529.53
RM-N091247
4-methyl-N-(3-(2-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide

Nilotinib Impurity 48
CAS:122228-09-5
Formula: C9H11N3O2
193.21
RM-N091248
methyl 4-guanidinobenzoate

NILOTINIB IMPURITY 5
CAS:2119583-24-1
Formula: C29H24F3N7O
543.54
RM-N091205
N-(3-(4-ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide

Nilotinib Impurity 50
CAS:641571-06-4
Formula: C11H10F3N3
241.22
RM-N091250
3-(2-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline

Nilotinib Impurity 51
CAS:2925306-68-7
Formula: C28H21F3N8O2
558.53
RM-N091251
4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide

Nilotinib Impurity 52
Formula: C17H13N5O3
335.32
RM-N091252
4-methyl-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoic acid

Nilotinib Impurity 53
Formula: C19H17N5O3
363.38
RM-N091253
ethyl 4-methyl-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate

Nilotinib Impurity 54
Formula: C9H9N3O2
191.19
RM-N091254
(E)-N-methyl-N-(3-oxo-3-(pyridin-3-yl)prop-1-en-1-yl)nitrous amide

Nilotinib Impurity 55
Formula: C11H14N4O3
250.26
RM-N091255
ethyl 4-methyl-3-(1-nitrosoguanidino)benzoate

Nilotinib Impurity 56
CAS:736080-30-1
Formula: C10H13N3O2
207.23
RM-N091256
methyl 4-(guanidinomethyl)benzoate

Nilotinib Impurity 57
Formula: C28H22F3N7O2
545.53
RM-N091257
2-((2-methyl-5-((3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)carbamoyl)phenyl)amino)-4-(pyridin-3-yl)pyrimidine 1-oxide

Nilotinib Impurity 58
Formula: C28H22F3N7O3
561.53
RM-N091258
2-((2-methyl-5-((3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)carbamoyl)phenyl)amino)-4-(1-oxidopyridin-3-yl)pyrimidine 1-oxide

NILOTINIB IMPURITY 6
CAS:641571-15-5
Formula: C28H22F3N7O
529.52
RM-N091206
4-methyl-N-(3-(5-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide

Nilotinib Impurity 60
CAS:15504-60-6
Formula: C12H15NO2
205.11
RM-N091260
(3-hydroxyphenyl)(piperidin-1-yl)methanone

Nilotinib Impurity 61
CAS:1026727-75-2
Formula: C9H9N3O
175.19
RM-N091261
2-amino-7-methylquinazolin-4(3H)-one

Nilotinib Impurity 62
CAS:1345336-53-9
Formula: C20H19F3N6O
416.41
RM-N091262
3-guanidino-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide

Nilotinib Impurity 63
CAS:1205540-16-4
Formula: C24H17BrF3N5O
528.33
RM-N091263
N-(3-bromo-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide

Nilotinib Impurity 64
CAS:1157857-29-8
Formula: C19H15F3N4O3
404.35
RM-N091264
4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-nitrobenzamide

NILOTINIB IMPURITY 7
CAS:2119583-26-3
Formula: C27H20F3N7O
515.49
RM-N091207
N-(3-(1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide

NILOTINIB N-OXIDE (IMIDAZOLE N-OXIDE)
CAS:2139382-75-3
Formula: C28H22F3N7O2
545.52
RM-N091208
4-methyl-1-(3-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamido)-5-(trifluoromethyl)phenyl)-1H-imidazole 3-oxide

NILOTINIB N-OXIDE (PYRIMIDINE N-OXIDE)
Formula: C28H22F3N7O2
545.52
RM-N091209
2-((2-methyl-5-((3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)carbamoyl)phenyl)amino)-6-(pyridin-3-yl)pyrimidine 1-oxide

Nilotinib Nitroso Impurity 59
Formula: C28H21F3N8O3
574.52
RM-N091259
3-(2-((2-methyl-5-((3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)carbamoyl)phenyl)(nitroso)amino)pyrimidin-4-yl)pyridine 1-oxide

NILOTINIB-D6
CAS:1268356-17-7
Formula: C28H16D6F3N7O
535.56
RM-N091238
4-(methyl-d3)-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide-2,5,6-d3

NILUTAMIDE
CAS:63612-50-0
Formula: C12H10F3N3O4
317.22
RM-N091300
5,5-dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)imidazolidine-2,4-dione

NILUTAMIDE EP IMPURITY A
Formula: C12H11F3N4O3
316.24
RM-N091301
5-imino-4,4-dimethyl-1-(4-nitro-3-(trifluoromethyl)phenyl)imidazolidin-2-one

NILUTAMIDE EP IMPURITY C
Formula: C12H9F3N2O5
318.21
RM-N091303
5,5-dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)oxazolidine-2,4-dione

NILUTAMIDE EP IMPURITY D
Formula: C15H8F6N4O5
438.24
RM-N091304
1,3-bis(4-Nitro-3-(trifluoromethyl)phenyl)urea

NIMBOLIDE
CAS:25990-37-8
Formula: C27H30O7
466.52
RM-N130200
Nimbolide

NIMESULIDE
CAS:51803-78-2
Formula: C13H12N2O5S
308.31
RM-N131900
N-(4-Nitro-2-phenoxyphenyl)methanesulphonamide

NIMESULIDE D5
CAS:1330180-22-7
Formula: C13H7D5N2O5S
313.34
RM-N131909
N-(4-nitro-2-(phenoxy-d5)phenyl)methanesulfonamide

NIMESULIDE EP IMPURITY A
CAS:51765-56-1
Formula: C13H11N3O7S
353.31
RM-N131901
N-(2,4-Dinitro-6-phenoxyphenyl)methanesulphonamide

NIMESULIDE EP IMPURITY B
CAS:51765-51-6
Formula: C13H13NO3S
263.31
RM-N131902
N-(2-Phenoxyphenyl)methanesulphonamide

NIMESULIDE EP IMPURITY C
CAS:2688-84-8
Formula: C12H11NO
185.22
RM-N131903
2-phenoxyaniline

NIMESULIDE EP IMPURITY D
CAS:5422-92-4
Formula: C12H10N2O3
230.22
RM-N131904
4-nitro-2-phenoxyaniline

NIMESULIDE EP IMPURITY E
CAS:905858-63-1
Formula: C14H15NO5S2
341.4
RM-N131905
N,N-bis(methylsulphonyl)-2-phenoxyaniline

NIMESULIDE EP IMPURITY F
CAS:51765-72-1
Formula: C14H14N2O7S2
386.4
RM-N131906
N,N-bis(methylsulphonyl)-4-nitro-2-phenoxyaniline

NIMESULIDE EP IMPURITY G
CAS:70995-08-3
Formula: C12H9NO4
231.2
RM-N131907
4-Nitro-2-phenoxyphenol

Nimesulide Impurity 10
CAS:109032-22-6
Formula: C13H12N2O6S
324.31
RM-N131910
N-(2-(4-Hydroxyphenoxy)-4-nitrophenyl)methanesulfonamide

Nimesulide Impurity 11
CAS:38880-53-4
Formula: C7H8N2O5S
232.21
RM-N131911
N-(2-hydroxy-4-nitrophenyl)methanesulfonamide

Nimesulide Impurity 12
Formula: C13H12N2O5S
308.31
RM-N131912
N-(2-nitro-6-phenoxyphenyl)methanesulfonamide

NIMESULIDE IMPURITY 8
CAS:2216-12-8
Formula: C12H9NO3
215.2
RM-N131908
1-nitro-2-phenoxybenzene

NIMODIPINE
CAS:66085-59-4
Formula: C21H26N2O7
418.44
RM-N131500
(R)-3-isopropyl 5-(2-methoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

NIMODIPINE EP IMPURITY A
CAS:85677-93-6
Formula: C21H24N2O7
416.42
RM-N131501
3-isopropyl 5-(2-methoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate

NIMODIPINE EP IMPURITY B
CAS:21881-78-7
Formula: C21H26N2O6
402.44
RM-N131536
diisopropyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

NIMODIPINE EP IMPURITY C
CAS:70172-96-2
Formula: C21H26N2O8
434.44
RM-N131503
bis(2-Methoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

NIMODIPINE IMPURITY 1
Formula: C13H12ClNO5
297.69
RM-N131527
(Z)-2-chloroethyl 2-(4-nitrobenzylidene)-3-oxobutanoate

NIMODIPINE IMPURITY 11
CAS:85677-95-8
Formula: C18H20N2O7
376.36
RM-N131537
3-(2-hydroxyethyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

NIMODIPINE IMPURITY 12
CAS:39562-18-0
Formula: C19H22N2O6
374.39
RM-N131538
3-isopropyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nimodipine Impurity 13(Dehydro Nicardipine); Nicardipine Hydrochloride EP Impurity A
CAS:59875-58-0
Formula: C26H27N3O6
477.51
RM-N131539
3-(2-(benzyl(methyl)amino)ethyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate

Nimodipine Impurity 14
CAS:103-67-3
Formula: C8H11N
121.18
RM-N131540
N-methyl-1-phenylmethanamine

NIMODIPINE IMPURITY 15
CAS:2098250-42-9
Formula: C26H30ClN3O6
515.99
RM-N131541
3-(2-(benzyl(methyl)amino)ethyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride

NIMODIPINE IMPURITY 16
CAS:58368-87-9
Formula: C19H23N3O6
389.41
RM-N131542
3-Methyl 5-(2-(methylamino)ethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nimodipine Impurity 17
CAS:123973-71-7
Formula: C25H27N3O6
465.5
RM-N131543
5-((2-(benzyl(methyl)amino)ethoxy)carbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid

Nimodipine Impurity 18
Formula: C23H23N3O5
421.45
RM-N131544
methyl 5-(benzylcarbamoyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate

Nimodipine Impurity 19; Nicardipine Hydrochloride EP Impurity B
CAS:71791-90-7
Formula: C35H40N4O6
612.73
RM-N131545
bis(2-(benzyl(methyl)amino)ethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

NIMODIPINE IMPURITY 2
CAS:62760-01-4
Formula: C13H12ClNO5
297.69
RM-N131528
(Z)-2-chloroethyl 2-(2-nitrobenzylidene)-3-oxobutanoate

NIMODIPINE IMPURITY 21
CAS:74936-76-8
Formula: C18H20N2O7
376.36
RM-N131547
5-((2-methoxyethoxy)carbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid

NIMODIPINE IMPURITY 22
CAS:39562-21-5
Formula: C20H24N2O6
388.41
RM-N131548
3-ethyl 5-isopropyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nimodipine Impurity 23
Formula: C20H24N2O7
404.41
RM-N131549
3-ethyl 5-(2-methoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nimodipine Impurity 24
Formula: C39H40N4O14
788.75
RM-N131550
3-(2-hydroxy-3-((5-((2-methoxyethoxy)carbonyl)-2,6-dimethyl-4-(3-nitrophenyl)nicotinoyl)oxy)propyl) 5-isopropyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate

Nimodipine Impurity 25
Formula: C21H26N2O7
418.44
RM-N131551
3-isopropyl 5-(2-methoxyethyl) 2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nimodipine Impurity 26
Formula: C21H26N2O7
418.44
RM-N131552
3-isopropyl 5-(2-methoxyethyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nimodipine Impurity 27
CAS:85677-94-7
Formula: C18H18N2O6
358.35
RM-N131553
5-(isopropoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)nicotinic acid

Nimodipine Impurity 28
CAS:82219-48-5
Formula: C20H22N2O7
402.4
RM-N131554
3-(2-hydroxyethyl) 5-isopropyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate

Nimodipine Impurity 29
Formula: C21H27NO5
373.45
RM-N131555
3-isopropyl 5-(2-methoxyethyl) 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate

NIMODIPINE IMPURITY 3
CAS:101072-61-1
Formula: C11H9NO5
235.19
RM-N131529
2-(3-nitrobenzylidene)-3-oxobutanoic acid

Nimodipine Impurity 30
Formula: C42H52N4O11
788.9
RM-N131556
1,2-bis(3-(3-(isopropoxycarbonyl)-5-((2-methoxyethoxy)carbonyl)-2,6-dimethyl-1,4-dihydropyridin-4-yl)phenyl)diazene 1-oxide

Nimodipine Impurity 31
Formula: C21H26N2O6
402.45
RM-N131557
3-isopropyl 5-(2-methoxyethyl) 2,6-dimethyl-4-(3-nitrosophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nimodipine Impurity 32
Formula: C22H28N2O6
416.47
RM-N131558
3-isopropyl 5-(2-methoxyethyl) 4-(3-formamidophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Nimodipine Impurity 33
CAS:155861-24-8
Formula: C21H28N2O5
388.46
RM-N131559
3-isopropyl 5-(2-methoxyethyl) 4-(3-aminophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Nimodipine Impurity 34
CAS:82219-47-4
Formula: C20H24N2O7
404.42
RM-N131560
3-(2-hydroxyethyl) 5-isopropyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nimodipine Impurity 35
CAS:21112-45-8
Formula: C4H7NO2
101.11
RM-N131561
3-aminobut-2-enoic acid

Nimodipine Impurity 36
Formula: C21H26N2O6
402.45
RM-N131562
3-isopropyl 5-(2-methoxyethyl) 4-(3-(hydroxyamino)phenyl)-2,6-dimethylpyridine-3,5-dicarboxylate

Nimodipine Impurity 37
Formula: C21H26N2O6
402.45
RM-N131563
diisopropyl 4,6-dimethyl-2-(3-nitrophenyl)-1,2-dihydropyridine-3,5-dicarboxylate

NIMODIPINE IMPURITY 4
CAS:1467606-81-0
Formula: C4H7NO2
101.1
RM-N131530
(E)-3-aminobut-2-enoic acid

Nimodipine Impurity 40
Formula: C42H52N4O10
772.9
RM-N131566
3-diisopropyl 5-bis(2-methoxyethyl) 4,4'-(diazene-1,2-diylbis(3,1-phenylene))-bis(2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate)

Nimodipine Impurity 41
Formula: C42H52N4O10
772.9
RM-N131567
3-diisopropyl 5-bis(2-methoxyethyl) 4,4'-(diazene-1,2-diylbis(3,1-phenylene))(Z)-bis(2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate)

Nimodipine Impurity 42
Formula: C42H54N4O10
774.91
RM-N131568
3-diisopropyl 5-bis(2-methoxyethyl) 4,4'-(hydrazine-1,2-diylbis(3,1-phenylene))bis(2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate)

Nimodipine Impurity 43
Formula: C14H16O4
248.28
RM-N131569
2-methoxyethyl (E)-2-benzylidene-3-oxobutanoate

Nimodipine Impurity 44
Formula: C14H16O4
248.28
RM-N131570
2-methoxyethyl (Z)-2-benzylidene-3-oxobutanoate

Nimodipine Impurity 45
Formula: C18H21N3O6
375.38
RM-N131571
2-methoxyethyl 5-carbamoyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate

Nimodipine Impurity 46
Formula: C14H15NO6
293.28
RM-N131572
2-methoxyethyl (Z)-2-(3-nitrobenzylidene)-3-oxobutanoate

Nimodipine Impurity 47
Formula: C11H15NO3
209.25
RM-N131573
2-methoxyethyl 2,6-dimethylnicotinate

Nimodipine Impurity 48
Formula: C42H52N4O11
788.9
RM-N131574
(Z)-1,2-bis(3-(3-(isopropoxycarbonyl)-5-((2-methoxyethoxy)carbonyl)-2,6-dimethyl-1,4-dihydropyridin-4-yl)phenyl)diazene 1-oxide

Nimodipine Impurity 49
CAS:1824037-63-9
Formula: C11H9NO5
235.2
RM-N131575
(Z)-2-(3-nitrobenzylidene)-3-oxobutanoic acid

NIMODIPINE IMPURITY 5
CAS:62760-10-5
Formula: C13H12ClNO5
297.69
RM-N131531
(Z)-2-chloroethyl 2-(3-nitrobenzylidene)-3-oxobutanoate

Nimodipine Impurity 50
Formula: C18H21N3O5
359.38
RM-N131576
isopropyl 5-carbamoyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate

Nimodipine Impurity 51
Formula: C15H12N2O6
316.27
RM-N131577
2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylic acid

Nimodipine Impurity 52
Formula: C21H24N2O8
432.43
RM-N131578
3-(isopropoxycarbonyl)-5-((2-methoxyethoxy)carbonyl)-2,6-dimethyl-4-(3-nitrophenyl)pyridine 1-oxide

Nimodipine Impurity 53
Formula: C18H18N2O7
374.35
RM-N131579
5-((2-methoxyethoxy)carbonyl)-2,6-dimethyl-4-(3-nitrophenyl)nicotinic acid

NIMODIPINE IMPURITY 6
CAS:80012-11-9
Formula: C5H9NO2
115.13
RM-N131532
(E)-methyl 3-aminobut-2-enoate

Nimodipine Impurity 8
CAS:74936-81-5
Formula: C15H14N2O6
318.28
RM-N131534
2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid

NIMODIPINE IMPURITY 9
CAS:87966-40-3
Formula: C18H17ClN2O6
392.79
RM-N131535
3-(2-chloroethyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate

Nimodipine Nitroso Impurity 54
Formula: C21H25N3O9
463.44
RM-N131580
bis(2-methoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1-nitroso-1,4-dihydropyridine-3,5-dicarboxylate

Nimodipine Nitroso Impurity 55
Formula: C20H23N3O8
433.42
RM-N131581
3-ethyl 5-(2-methoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1-nitroso-1,4-dihydropyridine-3,5-dicarboxylate

NIMODIPINE-D7
CAS:1246815-36-0
Formula: C21H19D7N2O7
425.49
RM-N131564
3-(2-methoxyethyl) 5-(propan-2-yl-d7) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

NINHYDRIN
CAS:485-47-2
Formula: C9H6O4
178.14
RG-N020000
2,2-dihydroxy-1H-indene-1,3(2H)-dione

NINTEDANIB
CAS:656247-17-5
Formula: C31H33N5O4
539.62
RM-N140400
(Z)-Methyl 3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB CARBOXYLIC ACID
CAS:894783-71-2
Formula: C30H31N5O4
525.6
RM-N140410
(Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic acid

NINTEDANIB E-ISOMER
Formula: C31H33N5O4
539.62
RM-N140405
(E)-methyl 3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB ESYLATE
CAS:656247-18-6
Formula: C31H33N5O4 C2H6O3S
539.64 110.13
RM-N140404
(Z)-methyl 3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate ethanesulfonate

NINTEDANIB IMPURITY 1
CAS:1027407-75-5
Formula: C21H19NO5
365.38
RM-N140401
(Z)-methyl 1-acetyl-3-(ethoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

Nintedanib Impurity 101
Formula: C28H40N8O2
520.68
RM-N140501
(E)-N,N'-(diazene-1,2-diylbis(4,1-phenylene))bis(N-methyl-2-(4-methylpiperazin-1-yl)acetamide)

Nintedanib Impurity 102
Formula: C28H40N8O3
536.68
RM-N140502
(Z)-1,2-bis(4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)diazene 1-oxide

NINTEDANIB IMPURITY 103
CAS:1139458-48-2
Formula: C26H23N3O4
441.49
RM-N140503
methyl (Z)-3-(((4-(N-methylacetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 104
Formula: C29H31N5O2
481.6
RM-N140504
N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-(((2-oxoindolin-3-ylidene)(phenyl)methyl)amino)phenyl)acetamide

NINTEDANIB IMPURITY 105
CAS:58378-33-9
Formula: C10H14O3
182.22
RM-N140505
1-(dimethoxymethyl)-2-methoxybenzene

NINTEDANIB IMPURITY 106
CAS:54699-92-2
Formula: C7H14N2O2
158.2
RM-N140506
2-(4-methylpiperazin-1-yl)acetic acid

NINTEDANIB IMPURITY 107
CAS:2770008-35-8
Formula: C14H13NO5
275.26
RM-N140507
methyl 1,3-diacetyl-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 108
Formula: C16H17NO6
319.31
RM-N140508
methyl 2-acetoxy-1,3-diacetylindoline-6-carboxylate

NINTEDANIB IMPURITY 11
Formula: C31H33N5O5
555.64
RM-N140411
(Z)-1-(2-((4-(((6-(methoxycarbonyl)-2-oxoindolin-3-ylidene)(phenyl)methyl)amino)phenyl)(methyl)amino)-2-oxoethyl)-4-methylpiperazine 1-oxide

NINTEDANIB IMPURITY 111
CAS:139408-99-4
Formula: C11H15ClO2
214.69
RM-N140511
(chlorodiethoxymethyl)benzene

Nintedanib Impurity 112
Formula: C11H16O3
196.25
RM-N140512
diethoxy(phenyl)methanol

NINTEDANIB IMPURITY 114
CAS:22911-21-3
Formula: C10H13ClO3
216.66
RM-N140514
1-Chloro-4-(trimethoxymethyl)benzene

Nintedanib Impurity 115
CAS:70138-33-9
Formula: C10H13ClO3
216.66
RM-N140515
1-chloro-2-(trimethoxymethyl)benzene

Nintedanib Impurity 116
Formula: C33H35N5O6
597.67
RM-N140516
(Z)-4-(2-((4-(((1-acetyl-6-(methoxycarbonyl)-2-oxoindolin-3-ylidene)(phenyl)methyl)amino)phenyl)(methyl)amino)-2-oxoethyl)-1-methylpiperazine 1-oxide

NINTEDANIB IMPURITY 12
Formula: C31H33N5O6
571.63
RM-N140412
(Z)-1-(2-((4-(((6-(methoxycarbonyl)-2-oxoindolin-3-ylidene)(phenyl)methyl)amino)phenyl)(methyl)amino)-2-oxoethyl)-4-methylpiperazine 1,4-dioxide

NINTEDANIB IMPURITY 122
Formula: C15H17NO5
291.3
RM-N140522
methyl 1,3-diacetyl-2-methoxyindoline-6-carboxylate

Nintedanib Impurity 123
CAS:334952-09-9
Formula: C9H7NO3
177.16
RM-N140523
2-oxoindoline-6-carboxylic acid

Nintedanib Impurity 124
Formula: C16H11NO4
281.26
RM-N140524
3-benzoyl-2-oxoindoline-6-carboxylic acid

NINTEDANIB IMPURITY 125
CAS:2243384-71-4
Formula: C13H20N4O
248.32
RM-N140525
N-(4-aminophenyl)-N-methyl-2-(piperazin-1-yl)acetamide

Nintedanib Impurity 126
Formula: C9H9NO4
195.17
RM-N140526
3-amino-4-(carboxymethyl)benzoic acid

Nintedanib Impurity 127
Formula: C33H35N5O5
581.66
RM-N140527
(E)-methyl 1-acetyl-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Nintedanib Impurity 128
Formula: C30H31N5O4
525.6
RM-N140528
(E)-methyl 3-(((4-(N-methyl-2-(piperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 129
Formula: C24H21N3O3
399.44
RM-N140529
(E)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 13
Formula: C32H32N6O4
564.65
RM-N140413
methyl (Z)-3-(((4-(2-(2-cyano-4-methylpiperazin-1-yl)-N-methylacetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 130
Formula: C30H31N5O4
525.6
RM-N140530
(E)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic acid

Nintedanib Impurity 131
Formula: C24H24N2O4
404.46
RM-N140531
(E)-methyl 1-acetyl-2-oxo-3-(phenyl(piperidin-1-yl)methylene)indoline-6-carboxylat

Nintedanib Impurity 132
Formula: C22H22N2O3
362.42
RM-N140532
(E)-methyl 2-oxo-3-(phenyl(piperidin-1-yl)methylene)indoline-6-carboxylate

NINTEDANIB IMPURITY 133
CAS:262368-25-2
Formula: C13H20N4O
248.32
RM-N140533
N-(4-aminophenyl)-2-(4-methylpiperazin-1-yl)acetamide

Nintedanib Impurity 134
Formula: C35H40N6O3
592.73
RM-N140534
(E)-N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-(((2-oxo-6-(piperidine-1-carbonyl)indolin-3-ylidene)(phenyl)methyl)amino)phenyl)acetamide

NINTEDANIB IMPURITY 14
Formula: C32H32N6O4
564.65
RM-N140414
methyl (Z)-3-(((4-(2-(3-cyano-4-methylpiperazin-1-yl)-N-methylacetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 15
CAS:2218446-42-3
Formula: C17H13NO4
295.29
RM-N140415
methyl 3-benzoyl-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 16
CAS:2036139-30-5
Formula: C17H13NO4
295.29
RM-N140416
methyl (E)-3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 17
CAS:14192-26-8
Formula: C10H9NO3
191.19
RM-N140417
Methyl 2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 18
Formula: C18H15NO4
309.32
RM-N140418
methyl (Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 19
Formula: C33H34ClN5O5
616.12
RM-N140419
methyl (Z)-1-(2-chloroacetyl)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 2
CAS:262368-30-9
Formula: C14H22N4O
262.35
RM-N140402
N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide

NINTEDANIB IMPURITY 20
CAS:334951-61-0
Formula: C30H31N5O4
525.61
RM-N140420
methyl (Z)-3-(((4-(N-methyl-2-(piperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 21
Formula: C29H31N5O2
481.6
RM-N140421
(Z)-N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-(((2-oxoindolin-3-ylidene)(phenyl)methyl)amino)phenyl)acetamide

NINTEDANIB IMPURITY 22
CAS:1895918-24-7
Formula: C10H9NO4
207.19
RM-N140422
methyl 1-hydroxy-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 23
CAS:1160293-25-3
Formula: C12H10ClNO4
267.67
RM-N140423
Methyl 1-(2-chloroacetyl)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 24
CAS:2653-15-8
Formula: C9H9ClN2O3
228.63
RM-N140424
2-chloro-N-methyl-N-(2-nitrophenyl)acetamide

NINTEDANIB IMPURITY 25
CAS:34539-21-4
Formula: C8H10N2O2
166.18
RM-N140425
N,N-DIMETHYL-4-NITROANILINE

NINTEDANIB IMPURITY 26
CAS:1038972-16-5
Formula: C13H18N4O3
278.31
RM-N140426
N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide

NINTEDANIB IMPURITY 3
CAS:2093243-16-2
Formula: C17H13NO4
295.29
RM-N140403
(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

Nintedanib Impurity 46
Formula: C14H22N4O
262.36
RM-N140446
N-(2-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide

Nintedanib Impurity 47
Formula: C34H31N5O4
573.65
RM-N140447
1-benzyl-6-(dimethylcarbamoyl)-2-methyl-1H-benzo[d]imidazol-4-yl 1-benzyl-4-hydroxy-2-methyl-1H-benzo[d]imidazole-6-carboxylate

Nintedanib Impurity 48
Formula: C21H26N4O2
366.47
RM-N140448
1-benzyl-7-((dimethylamino)methyl)-4-hydroxy-N,N,2-trimethyl-1H-benzo[d]imidazole-6-carboxamide

NINTEDANIB IMPURITY 49
CAS:1139455-52-9
Formula: C32H35N5O4
553.66
RM-N140449
ethyl (Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 50
CAS:1253768-91-0
Formula: C16H11NO4
281.27
RM-N140450
(Z)-3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylic acid

Nintedanib Impurity 51
CAS:2734676-68-5
Formula: C31H33N5O6
571.63
RM-N140451
1-(2-((4-(((6-(methoxycarbonyl)-2-oxoindolin-3-ylidene)(phenyl)methyl)amino)phenyl)(methyl)amino)-2-oxoethyl)-4-methylpiperazine 1,4-dioxide

NINTEDANIB IMPURITY 52
CAS:2410649-54-4
Formula: C22H26N6O6
470.49
RM-N140452
2,2'-(piperazine-1,4-diyl)bis(N-methyl-N-(4-nitrophenyl)acetamide)

Nintedanib Impurity 53
CAS:2410284-90-9
Formula: C56H52N8O8
965.08
RM-N140453
dimethyl 3,3'-(((((2,2'-(piperazine-1,4-diyl)bis(acetyl))bis(methylazanediyl))bis(4,1-phenylene))bis(azanediyl))bis(phenylmethaneylylidene))(3Z,3'Z)-bis(2-oxoindoline-6-carboxylate)

Nintedanib Impurity 54
Formula: C15H24N4O
276.38
RM-N140454
N-methyl-N-(4-(methylamino)phenyl)-2-(4-methylpiperazin-1-yl)acetamide

Nintedanib Impurity 55
CAS:2186-92-7
Formula: C10H14O3
182.22
RM-N140455
1-(dimethoxymethyl)-4-methoxybenzene

Nintedanib Impurity 56
CAS:1624587-84-3
Formula: C31H30D3N5O4
542.65
RM-N140456
methyl (Z)-3-(((4-(N-methyl-2-(4-(methyl-d3)piperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 58
Formula: C19H18N2O3
322.36
RM-N140458
methyl (E)-3-((dimethylamino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Nintedanib Impurity 59
Formula: C22H23N3O3
377.44
RM-N140459
methyl (E)-3-((4-methylpiperazin-1-yl)(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 6
CAS:2734666-06-7
Formula: C31H33N5O5
555.62
RM-N140406
(Z)-4-(2-((4-(((6-(methoxycarbonyl)-2-oxoindolin-3-ylidene)(phenyl)methyl)amino)phenyl)(methyl)amino)-2-oxoethyl)-1-methylpiperazine 1-oxide

Nintedanib Impurity 60
CAS:2101947-36-6
Formula: C22H23N3O3
377.44
RM-N140460
methyl 3-((4-methylpiperazin-1-yl)(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 61
CAS:2454314-41-9
Formula: C19H18N2O3
322.36
RM-N140461
methyl 3-((dimethylamino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 62
Formula: C21H19NO5
365.39
RM-N140462
ethyl (Z)-1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 63
CAS:954239-49-7
Formula: C11H11NO3
205.21
RM-N140463
Ethyl 2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 64
Formula: C14H20N4O3
292.34
RM-N140464
N-methyl-2-(4-methylpiperazin-1-yl)-N-(2-nitrophenyl)acetamide

NINTEDANIB IMPURITY 65
CAS:2380229-45-6
Formula: C33H35N5O5
581.67
RM-N140465
methyl (Z)-1-acetyl-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Nintedanib Impurity 66
CAS:2295911-98-5
Formula: C32H35N5O4
553.66
RM-N140466
ethyl 3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 67
Formula: C35H39N5O6
625.73
RM-N140467
methyl (Z)-3-(((4-(2-(4-(tert-butoxycarbonyl)piperazin-1-yl)-N-methylacetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 68
CAS:17329-87-2
Formula: C8H7ClN2O3
214.61
RM-N140468
2-chloro-N-(4-nitrophenyl)acetamide

NINTEDANIB IMPURITY 69
Formula: C35H40N6O3
592.74
RM-N140469
(Z)-N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-(((2-oxo-6-(piperidine-1-carbonyl)indolin-3-ylidene)(phenyl)methyl)amino)phenyl)acetamide

NINTEDANIB IMPURITY 7
CAS:1987887-92-2
Formula: C24H21N3O3
399.44
RM-N140407
(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 70
CAS:2102162-79-6
Formula: C22H22N2O3
362.43
RM-N140470
methyl (Z)-2-oxo-3-(phenyl(piperidin-1-yl)methylene)indoline-6-carboxylate

Nintedanib Impurity 71
CAS:16346-60-4
Formula: C8H6Cl2N2O3
249.05
RM-N140471
2,2-dichloro-N-(4-nitrophenyl)acetamide

NINTEDANIB IMPURITY 72
CAS:708279-23-6
Formula: C13H18N4O3
278.31
RM-N140472
2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide

NINTEDANIB IMPURITY 73
CAS:4306-32-5
Formula: C8H5Cl3N2O3
283.49
RM-N140473
2,2,2-trichloro-N-(4-nitrophenyl)acetamide

Nintedanib Impurity 74
CAS:1860012-61-8
Formula: C9H10N2O4
210.19
RM-N140474
2-hydroxy-N-methyl-N-(4-nitrophenyl)acetamide

NINTEDANIB IMPURITY 75
Formula: C9H10Cl2N2O
233.09
RM-N140475
N-(4-aminophenyl)-2,2-dichloro-N-methylacetamide

NINTEDANIB IMPURITY 76
CAS:78466-25-8
Formula: C9H8Cl2N2O3
263.07
RM-N140476
2,2-dichloro-N-methyl-N-(4-nitrophenyl)acetamide

NINTEDANIB IMPURITY 77
CAS:98953-48-1
Formula: C9H10N2O4
210.19
RM-N140477
N-methyl-N-(4-nitrophenyl)glycine

NINTEDANIB IMPURITY 78
Formula: C12H11NO4
233.22
RM-N140478
methyl 3-acetyl-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 79
Formula: C34H37N5O5
595.7
RM-N140479
ethyl (Z)-1-acetyl-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 8
CAS:2410284-89-6
Formula: C22H30N6O2
410.51
RM-N140408
2,2'-(Piperazine-1,4-diyl)bis(N-(4-aminophenyl)-N-methylacetamide)

Nintedanib Impurity 80
Formula: C14H13NO7
307.26
RM-N140480
trimethyl 2-oxoindoline-1,3,6-tricarboxylate

Nintedanib Impurity 81
Formula: C13H13NO3
231.25
RM-N140481
methyl 2-oxo-3-(propan-2-ylidene)indoline-6-carboxylate

NINTEDANIB IMPURITY 82
CAS:21905-78-2
Formula: C10H9NO2
175.19
RM-N140482
1-acetylindolin-2-one

Nintedanib Impurity 83
Formula: C24H24N2O4
404.47
RM-N140483
methyl (Z)-1-acetyl-2-oxo-3-(phenyl(piperidin-1-yl)methylene)indoline-6-carboxylate

Nintedanib Impurity 84
Formula: C9H9Cl3N2O
267.53
RM-N140484
N-(4-aminophenyl)-2,2,2-trichloro-N-methylacetamide

Nintedanib Impurity 85
CAS:126434-07-9
Formula: C9H7Cl3N2O3
297.52
RM-N140485
2,2,2-trichloro-N-methyl-N-(4-nitrophenyl)acetamide

Nintedanib Impurity 86
Formula: C12H11NO5
249.22
RM-N140486
dimethyl 2-oxoindoline-3,6-dicarboxylate

Nintedanib Impurity 87
CAS:1987887-93-3
Formula: C26H22ClN3O4
475.93
RM-N140487
methyl (Z)-3-(((4-(2-chloro-N-methylacetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Nintedanib Impurity 88
CAS:1277571-69-3
Formula: C18H26N4O5
378.43
RM-N140488
tert-butyl 4-(2-(methyl(4-nitrophenyl)amino)-2-oxoethyl)piperazine-1-carboxylate

Nintedanib Impurity 89
Formula: C9H11ClN2O
198.65
RM-N140489
N-(2-aminophenyl)-2-chloro-N-methylacetamide

Nintedanib Impurity 90
Formula: C32H35N5O4
553.66
RM-N140490
methyl (Z)-3-(((4-(2-(4-ethylpiperazin-1-yl)-N-methylacetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Nintedanib Impurity 91
CAS:676326-36-6
Formula: C12H11NO4
233.22
RM-N140491
Methyl 1-acetyl-2-oxoindoline-6-carboxylate

Nintedanib Impurity 92
Formula: C20H17NO5
351.36
RM-N140492
methyl (Z)-1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB IMPURITY 93
Formula: C29H29N5O4
511.58
RM-N140493
methyl (Z)-2-oxo-3-(phenyl((4-(2-(piperazin-1-yl)acetamido)phenyl)amino)methylene)indoline-6-carboxylate

Nintedanib Impurity 94
CAS:380427-39-4
Formula: C10H9NO3
191.19
RM-N140494
Methyl 2-oxoindoline-7-carboxylate

Nintedanib Impurity 95
CAS:119-63-1
Formula: C9H12N2O
164.21
RM-N140495
N-(4-Aminophenyl)-N-methylacetamide

Nintedanib Impurity 96
CAS:121-95-9
Formula: C9H10N2O3
194.19
RM-N140496
N-Methyl-N-(4-nitrophenyl)acetamide

Nintedanib Impurity 97
CAS:856843-88-4
Formula: C12H24N4O
240.35
RM-N140497
1,2-bis(4-methylpiperazin-1-yl)ethan-1-one

Nintedanib Impurity 98
Formula: C14H22N4O2
278.36
RM-N140498
N-(4-(hydroxyamino)phenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide

NINTEDANIB IMPURITY 99
Formula: C28H42N8O2
522.7
RM-N140499
N,N'-(hydrazine-1,2-diylbis(4,1-phenylene))bis(N-methyl-2-(4-methylpiperazin-1-yl)acetamide)

NINTEDANIB IMPURITY I
CAS:1168150-46-6
Formula: C18H15NO4
309.32
RM-I200409
(E)-methyl 3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

Nintedanib Nitroso Impurity 117
Formula: C31H32N6O5
568.63
RM-N140517
methyl (Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-1-nitroso-2-oxoindoline-6-carboxylate

Nintedanib Nitroso Impurity 118
Formula: C31H31N7O6
597.63
RM-N140518
methyl (Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-1-nitroso-2-oxoindoline-6-carboxylate

Nintedanib Nitroso Impurity 119
Formula: C24H20N4O4
428.45
RM-N140519
methyl (Z)-3-(((4-(methyl(nitroso)amino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Nintedanib Nitroso Impurity 120
Formula: C30H30N6O5
554.61
RM-N140520
Methyl (Z)-3-(((4-(N-methyl-2-(4-nitrosopiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Nintedanib Nitroso Impurity 121
Formula: C30H30N6O5
554.61
RM-N140521
methyl (Z)-3-(((4-(2-(4-methylpiperazin-1-yl)-N-nitrosoacetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Nintedanib-13C-d3
Formula: C3013CH30D3N5O4
543.65
RM-N140509
methyl (Z)-3-(((4-(N-methyl-2-(4-(methyl-13C-d3)piperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

NINTEDANIB-13C-D3 DEMETHYL-O-GLUCURONIDE
Formula: C3513CH36D3N5O10
705.74
RM-N140513
(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((Z)-3-(((4-(N-methyl-2-(4-(methyl-13C-d3)piperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carbonyl)oxy)tetrahydro-2H-pyran-2-carboxylic acid

Nintedanib-d8
Formula: C31H25D8N5O4
547.68
RM-N140510
methyl (Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

NIRAPARIB
CAS:1038915-60-4
Formula: C19H20N4O
320.39
RM-N090100
(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide

NIRAPARIB IMPURITY 1
CAS:1476777-06-6
Formula: C19H19N3O2
321.38
RM-N090101
(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxylic acid

Niraparib Impurity 10
CAS:1336754-69-8
Formula: C11H14BrN
240.14
RM-N090110
(R)-3-(4-bromophenyl)piperidine

Niraparib Impurity 12
Formula: C19H20N4O2
336.4
RM-N090112
(3S)-3-(4-(7-carbamoyl-2H-indazol-2-yl)phenyl)piperidine 1-oxide

Niraparib Impurity 13
Formula: C11H12N2O4
236.23
RM-N090113
methyl (E)-2-(2-(hydroxyimino)acetamido)-3-methylbenzoate

Niraparib Impurity 14
CAS:1203686-41-2
Formula: C16H22BrNO2
340.26
RM-N090114
tert-butyl 3-(3-bromophenyl)piperidine-1-carboxylate

Niraparib Impurity 15
CAS:1203683-54-8
Formula: C16H22BrNO2
340.26
RM-N090115
1,1-Dimethylethyl 3-(2-bromophenyl)-1-piperidinecarboxylate

Niraparib Impurity 16
CAS:1203682-58-9
Formula: C11H14BrN
240.14
RM-N090116
3-(3-bromophenyl)piperidine

Niraparib Impurity 18
CAS:2308483-84-1
Formula: C19H20N2O3
324.38
RM-N090118
(R)-3-(4-nitrophenyl)-1-((S)-1-phenylethyl)piperidin-2-one

Niraparib Impurity 19
CAS:2308483-83-0
Formula: C19H20N2O3
324.38
RM-N090119
(S)-3-(4-nitrophenyl)-1-((S)-1-phenylethyl)piperidin-2-one

NIRAPARIB IMPURITY 2
Formula: C19H20N4O
320.4
RM-N090102
(S)-1-(4-(piperidin-3-yl)phenyl)-1H-indazole-7-carboxamide

NIRAPARIB IMPURITY 3
Formula: C30H33N5O
479.63
RM-N090103
2-(4-((S)-1-(4-((S)-piperidin-3-yl)phenyl)piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide

Niraparib Impurity 4
CAS:1038915-58-0
Formula: C19H20N4O
320.4
RM-N090104
(R)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide

Niraparib Impurity 5
CAS:2244220-34-4
Formula: C20H21N3O2
335.41
RM-N090105
methyl (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxylate

Niraparib Impurity 6
Formula: C24H28N4O3
420.51
RM-N090106
tert-butyl (S)-3-(4-(7-carbamoyl-2H-indazol-2-yl)phenyl)piperidine-1-carboxylate

Niraparib Impurity 7
Formula: C19H18N4O
318.38
RM-N090107
2-(4-(1,4,5,6-tetrahydropyridin-3-yl)phenyl)-2H-benzo[d]imidazole-4-carboxamide

Niraparib Impurity 8
Formula: C25H27N3O8
497.5
RM-N090108
2-(4-((S)-1-((2R,3R,4S,5S,6S)-6-carboxy-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)piperidin-3-yl)phenyl)-2H-indazole-7-carboxylic acid

Niraparib Impurity 9
Formula: C25H27N3O8
497.5
RM-N090109
(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-((2-(4-((S)-piperidin-3-yl)phenyl)-2H-indazole-7-carbonyl)oxy)tetrahydro-2H-pyran-2-carboxylic acid

Niraparib Nitroso Impurity 11
Formula: C19H19N5O2
349.39
RM-N090111
(S)-2-(4-(1-nitrosopiperidin-3-yl)phenyl)-2H-indazole-7-carboxamide

Niraparib Nitroso Impurity 17
Formula: C24H28N4O3
420.51
RM-N090117
2-methyl-2-(4-(2-(4-(1-nitroso-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)ethyl)phenyl)propanoic acid

Nirmatrelvir Impurity 10
Formula: C16H24F3N3O3
363.38
RM-N070010
(1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 11
Formula: C25H35F3N6O8S
636.64
RM-N070011
methyl 3-((S)-1-((1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-2H-1,2,4-thiadiazete-2-carboxylate 1,1-dioxide

Nirmatrelvir Impurity 12
Formula: C21H33N5O3
403.53
RM-N070012
(1R,2S,5S)-3-((S)-2-amino-3,3-dimethylbutanoyl)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 13
CAS:394735-26-3
Formula: C20H34N2O5
382.5
RM-N070013
methyl (1R,2S,5S)-3-((S)-2-((tert-butoxycarbonyl)amino)-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate

Nirmatrelvir Impurity 14
Formula: C19H32N2O5
368.47
RM-N070014
(1R,2S,5S)-3-((S)-2-((tert-butoxycarbonyl)amino)-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid

Nirmatrelvir Impurity 15
Formula: C14H24N2O3
268.36
RM-N070015
(1R,2S,5S)-3-((S)-2-amino-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid

Nirmatrelvir Impurity 16
Formula: C24H35F3N4O6
532.56
RM-N070016
methyl (S)-2-((1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-3-((S)-2-oxopyrrolidin-3-yl)propanoate

Nirmatrelvir Impurity 17
Formula: C16H23F3N2O4
364.37
RM-N070017
(1R,2R,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid

Nirmatrelvir Impurity 18
Formula: C16H23F3N2O4
364.37
RM-N070018
(1R,2R,5S)-3-((R)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid

Nirmatrelvir Impurity 19
Formula: C16H23F3N2O4
364.37
RM-N070019
(1S,2S,5R)-3-((R)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid

Nirmatrelvir Impurity 2
CAS:2755812-81-6
Formula: C23H34F3N5O5
517.55
RM-N070002
(1R,2S,5S)-N-((S)-1-amino-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 20
Formula: C16H23F3N2O4
364.37
RM-N070020
(1S,2S,5R)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid

Nirmatrelvir Impurity 21
CAS:62965-35-9
Formula: C11H21NO4
231.29
RM-N070021
(S)-2-((tert-butoxycarbonyl)amino)-3,3-dimethylbutanoic acid

Nirmatrelvir Impurity 22
Formula: C25H31F6N5O5
595.54
RM-N070022
(1R,2S,5S)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoro-N-(2,2,2-trifluoroacetyl)acetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 23
CAS:21735-55-7
Formula: C8H12F3NO3
227.18
RM-N070023
(S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoic acid

Nirmatrelvir Impurity 24
Formula: C7H11N3O
153.19
RM-N070024
(S)-2-Amino-3-((S)-2-oxopyrrolidin-3-yl)propanenitrile

Nirmatrelvir Impurity 25
CAS:911835-76-2
Formula: C8H13NO2
155.2
RM-N070025
(1R,2S,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid

Nirmatrelvir Impurity 26
Formula: C23H32F3N5O4
499.54
RM-N070026
(1R,2S,5S)-N-((R)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((R)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 27
Formula: C23H32F3N5O4
499.54
RM-N070027
(1R,2R,5S)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 28
Formula: C23H32F3N5O4
499.54
RM-N070028
(1R,2S,5S)-N-((R)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 29
Formula: C23H32F3N5O4
499.54
RM-N070029
(1R,2S,5S)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((R)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 3
CAS:2755812-45-2
Formula: C16H23F3N2O4
364.37
RM-N070003
(1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid

Nirmatrelvir Impurity 30
Formula: C16H22N4O4
334.38
RM-N070030
(1R,2S,5S)-2-(((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)carbamoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexa(1R,2S,5S)-2-(((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)carbamoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-3-carboxylic acidne-3

Nirmatrelvir Impurity 31
Formula: C23H32F3N5O4
499.54
RM-N070031
(1R,2S,5S)-N-((S)-1-cyano-2-((R)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 32
CAS:943516-54-9
Formula: C7H13N
111.19
RM-N070032
6,6-dimethyl-3-azabicyclo[3.1.0]hexane

Nirmatrelvir Impurity 33
CAS:2713439-69-9
Formula: C12H21N3O4
271.32
RM-N070033
tert-butyl ((S)-1-amino-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)carbamate

Nirmatrelvir Impurity 34
CAS:943516-62-9
Formula: C9H15NO2
169.22
RM-N070034
methyl (1S,2R,5R)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate

Nirmatrelvir Impurity 35
Formula: C8H12F3NO3
227.18
RM-N070035
(R)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoic acid

Nirmatrelvir Impurity 36
Formula: C7H13N3O2
171.2
RM-N070036
(2S,4S)-4-(2-aminoethyl)-5-oxopyrrolidine-2-carboxamide

Nirmatrelvir Impurity 37
Formula: C7H13N3O2
171.2
RM-N070037
(4S,6S)-6-amino-7-oxoazepane-4-carboxamide

Nirmatrelvir Impurity 38
Formula: C7H13N3O2
171.2
RM-N070038
(R)-2-amino-3-((R)-2-oxopyrrolidin-3-yl)propanamide

Nirmatrelvir Impurity 39
Formula: C7H13N3O2
171.2
RM-N070039
(S)-2-amino-3-((R)-2-oxopyrrolidin-3-yl)propanamide

Nirmatrelvir Impurity 4
Formula: C16H22F3N3O2
345.37
RM-N070004
N-((S)-1-((1R,2S,5S)-2-cyano-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-3-yl)-3,3-dimethyl-1-oxobutan-2-yl)-2,2,2-trifluoroacetamide

Nirmatrelvir Impurity 40
Formula: C13H14F3N5O3
345.28
RM-N070040
3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl (S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoate

Nirmatrelvir Impurity 41
Formula: C22H26F3N5O4
481.48
RM-N070041
1H-benzo[d][1,2,3]triazol-1-yl (1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate

Nirmatrelvir Impurity 42
Formula: C21H32N4O4
404.51
RM-N070042
(1R,2S,5S)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-2-hydroxy-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 43
Formula: C15H22N4O2
290.37
RM-N070043
(1R,2S,5S)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 44
Formula: C23H34F3N5O5
517.55
RM-N070044
(2S,4S)-2-(2-aminoethyl)-4-cyano-4-((1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)butanoic acid

Nirmatrelvir Impurity 45
Formula: C23H33F3N4O6
518.53
RM-N070045
(2R,4S)-4-cyano-4-((1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-2-(2-hydroxyethyl)butanoic acid

Nirmatrelvir Impurity 46
Formula: C23H33F3N4O6
518.53
RM-N070046
(S)-2-((1R,2S,5S)-3-((S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-3-((S)-2-oxopyrrolidin-3-yl)propanoic acid

Nirmatrelvir Impurity 47
Formula: C25H31F6N5O5
595.54
RM-N070047
(1R,2S,5S)-N-((S)-1-cyano-2-((S)-2-oxo-1-(2,2,2-trifluoroacetyl)pyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 48
Formula: C25H31F6N5O5
595.54
RM-N070048
(1R,2S,5S)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-N-(2,2,2-trifluoroacetyl)-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 49
Formula: C24H34F3N3O5
501.55
RM-N070049
(1R,2S,5S)-3-((1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carbonyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid

Nirmatrelvir Impurity 5
CAS:2628280-47-5
Formula: C7H13N3O2
171.2
RM-N070005
(S)-2-Amino-3-((S)-2-oxopyrrolidin-3-yl)propanamide

Nirmatrelvir Impurity 50
Formula: C7H11D2N3O2
173.21
RM-N070050
(R)-2-amino-3-((S)-2-oxopyrrolidin-3-yl-5,5-d2)propanamide

Nirmatrelvir Impurity 51
Formula: C25H29D2F6N5O5
597.56
RM-N070051
(1R,2S,5S)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl-5,5-d2)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoro-N-(2,2,2-trifluoroacetyl)acetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 52
Formula: C23H31D2F3N4O6
520.55
RM-N070052
(S)-2-((1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-3-((S)-2-oxopyrrolidin-3-yl-5,5-d2)propanoic acid

Nirmatrelvir Impurity 53
Formula: C23H30D2F3N5O4
501.55
RM-N070053
(1R,2S,5S)-N-((R)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl-5,5-d2)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 54
Formula: C21H31D2N5O3
405.54
RM-N070054
(1R,2S,5S)-3-((S)-2-amino-3,3-dimethylbutanoyl)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl-5,5-d2)ethyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 55
Formula: C23H30D2F3N5O4
501.55
RM-N070055
(1R,2S,5S)-N-((R)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl-5,5-d2)ethyl)-3-((R)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 56
Formula: C23H30D2F3N5O4
501.55
RM-N070056
(1R,2S,5S)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl-5,5-d2)ethyl)-3-((R)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 57
CAS:169870-82-0
Formula: C11H21NO4
231.29
RM-N070057
2-((tert-butoxycarbonyl)amino)-3,3-dimethylbutanoic acid; N-[(1,1-Dimethylethoxy)carbonyl]-3-methylvaline; DL-Boc-tert-leucine; N_x0002_tert-Butoxycarbonyl-2-amino-3,3-dimethylbutyric acid; [(tert-Butoxycarbonyl)amino](tert-butyl)acetic aci

Nirmatrelvir Impurity 58
Formula: C26H39F3N4O6
560.62
RM-N070058
isopropyl (S)-2-((1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-3-((S)-2-oxopyrrolidin-3-yl)propanoate

Nirmatrelvir Impurity 59
Formula: C10H18N2O3
214.27
RM-N070059
isopropyl (S)-2-amino-3-((S)-2-oxopyrrolidin-3-yl)propanoate

Nirmatrelvir Impurity 6
Formula: C12H20N2O5
272.3
RM-N070006
(S)-2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoic acid

Nirmatrelvir Impurity 60
CAS:1037559-82-2
Formula: C8H12N2
136.2
RM-N070060
(1R,2S,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carbonitrile

Nirmatrelvir Impurity 61
CAS:1027601-37-1
Formula: C8H14N2O3
186.21
RM-N070061
Methyl (S)-2-amino-3-((S)-2-oxopyrrolidin-3-yl)propanoate

Nirmatrelvir Impurity 62
Formula: C23H32F3N5O4
499.54
RM-N070062
(1S,2R,5R)-N-((R)-1-cyano-2-((R)-2-oxopyrrolidin-3-yl)ethyl)-3-((R)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 63
CAS:1932478-97-1
Formula: C9H15NO2
169.22
RM-N070063
methyl (1S,2S,5R)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate

Nirmatrelvir Impurity 64
CAS:1932411-98-7
Formula: C9H15NO2
169.22
RM-N070064
methyl (1R,2R,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate

Nirmatrelvir Impurity 65
Formula: C12H19N3O3
253.3
RM-N070065
tert-butyl ((R)-1-cyano-2-((R)-2-oxopyrrolidin-3-yl)ethyl)carbamate

Nirmatrelvir Impurity 66
Formula: C23H32F3N5O4 C5H12O
499.54 88.15
RM-N070066
(1R,2S,5S)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide--2-methoxy-2-methylpropane (1/1)

Nirmatrelvir Impurity 67
Formula: C22H30F3N5O4 C3H8O
485.51 60.10
RM-N070067
(1S,2S,5R,6R)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6-methyl-3-azabicyclo[3.1.0]hexane-2-carboxamide--propan-2-ol (1/1)

Nirmatrelvir Impurity 68
Formula: C23H32F3N5O4
499.54
RM-N070068
(1R,2S,5S)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-(3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 69
Formula: C24H40F3N5O4
519.61
RM-N070069
(1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic (Z)-N-(3-(dimethylamino)propyl)-N'-ethylcarbamimidic anhydride

Nirmatrelvir Impurity 7
Formula: C7H12N2O3
172.18
RM-N070007
(S)-2-amino-3-((S)-2-oxopyrrolidin-3-yl)propanoic acid

Nirmatrelvir Impurity 70
Formula: C24H40F3N5O4
519.61
RM-N070070
(1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-N-(3-(dimethylamino)propyl)-N-(ethylcarbamoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 71
Formula: C14H24N2O3
268.36
RM-N070071
(1S,2R,5R)-3-((S)-2-amino-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid

Nirmatrelvir Impurity 72
Formula: C23H32F3N5O4
499.54
RM-N070072
(1S,2R,5R)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 73
Formula: C23H32F3N5O4
499.54
RM-N070073
(1R,2S,5S)-N-((R)-1-cyano-2-((R)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 74
Formula: C16H23F3N2O4
364.37
RM-N070074
(1S,2R,5R)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid

Nirmatrelvir Impurity 75
Formula: C16H23F3N2O4
364.37
RM-N070075
(1R,2S,5S)-3-((R)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid

Nirmatrelvir Impurity 76
Formula: C23H34F3N5O5
517.55
RM-N070076
(1R,2S,5S)-N-((R)-1-amino-1-oxo-3-((R)-2-oxopyrrolidin-3-yl)propan-2-yl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 77
Formula: C7H11N3O
153.19
RM-N070077
(R)-2-amino-3-((R)-2-oxopyrrolidin-3-yl)propanenitrile

Nirmatrelvir Impurity 78
Formula: C20H34N2O5
382.5
RM-N070078
methyl (1R,2S,5S)-3-((R)-2-((tert-butoxycarbonyl)amino)-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate

Nirmatrelvir Impurity 79
Formula: C19H32N2O5
368.47
RM-N070079
(1R,2S,5S)-3-((R)-2-((tert-butoxycarbonyl)amino)-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid

Nirmatrelvir Impurity 8
Formula: C17H25F3N2O4
378.39
RM-N070008
methyl (1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate

Nirmatrelvir Impurity 80
Formula: C14H24N2O3
268.36
RM-N070080
(1R,2S,5S)-3-((R)-2-amino-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid

Nirmatrelvir Impurity 81
Formula: C19H32N2O5
368.47
RM-N070081
(1S,2R,5R)-3-((S)-2-((tert-butoxycarbonyl)amino)-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid

Nirmatrelvir Impurity 82
Formula: C12H21N3O4
271.32
RM-N070082
tert-butyl ((R)-1-amino-1-oxo-3-((R)-2-oxopyrrolidin-3-yl)propan-2-yl)carbamate

Nirmatrelvir Impurity 83
Formula: C16H23N3O6
353.38
RM-N070083
dimethyl (S)-4-((tert-butoxycarbonyl)amino)-2,2-bis(cyanomethyl)pentanedioate

Nirmatrelvir Impurity 84
Formula: C20H34N2O5
382.5
RM-N070084
methyl (1S,2R,5R)-3-((S)-2-((tert-butoxycarbonyl)amino)-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate

Nirmatrelvir Impurity 85
Formula: C23H32F3N5O4
499.54
RM-N070085
(1R,2R,5S)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((R)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Nirmatrelvir Impurity 9
Formula: C18H27F3N2O4
392.42
RM-N070009
ethyl (1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate

Nirmatrelvir Impurity A
CAS:565456-77-1n+êHCln+ë
Formula: C9H15NO2
169.22
RG-A260270
methyl (1R,2S,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate

Nirmatrelvir Impurity B
CAS:956075-22-2
Formula: C9H15NO2
169.22
RG-A261443
methyl 6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate

NISIN
CAS:1414-45-5
Formula: C143H230N42O37S7
3354.07
RM-N135000
nsc-112903

NISOLDIPINE
CAS:63675-72-9
Formula: C20H24N2O6
388.42
RM-N190400
1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 2-methylpropyl ester

NISOLDIPINE IMPURITY B
CAS:61312-59-2
Formula: C15H17NO5
291.3
RM-N190402
(Z)-isobutyl 2-(2-nitrobenzylidene)-3-oxobutanoate

NISOLDIPINE IMPURITY C
CAS:103026-83-1
Formula: C20H22N2O6
386.4
RM-N190403
3-isobutyl 5-methyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate

NISOLDIPINE IMPURITY D
CAS:87375-91-5
Formula: C20H22N2O5
370.4
RM-N190404
3-isobutyl 5-methyl 2,6-dimethyl-4-(2-nitrosophenyl)pyridine-3,5-dicarboxylate

Nisoldipine Impurity E
Formula: C23H30N2O6
430.49
RM-N190405
Diisobutyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nisoldipine Impurity F
Formula: C20H24N2O6
388.41
RM-N190406
3-butyl 5-methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

NISOLDIPINE-D6
CAS:1285910-03-3
Formula: C20H18D6N2O6
394.46
RM-N190407
3-methyl 5-(2-(methyl-d3)propyl-3,3,3-d3) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

NITAZOXANIDE
CAS:55981-09-4
Formula: C12H9N3O5S
307.28
RM-N092600
2-((5-nitrothiazol-2-yl)carbamoyl)phenyl acetate

Nitazoxanide D4
CAS:1246819-17-9
Formula: C12H5D4N3O5S
311.3
RM-N092604
2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl-3,4,5,6-d4 acetate

NITAZOXANIDE IMPURITY 1
CAS:121-66-4
Formula: C3H3N3O2S
145.14
RM-N092601
5-nitrothiazol-2-amine

NITAZOXANIDE IMPURITY 2
CAS:173903-47-4
Formula: C10H7N3O4S
265.25
RM-N092602
2-hydroxy-N-(5-nitrothiazol-2-yl)benzamide

NITAZOXANIDE IMPURITY 3
CAS:952686-58-7
Formula: C19H13N3O7S
427.39
RM-N092603
2-((5-nitrothiazol-2-yl)carbamoyl)phenyl 2-acetoxybenzoate

NITENPYRAM
CAS:150824-47-8
Formula: C11H15ClN4O2
270.72
RM-N250000
(E)-Nitenpyram; (E)-N-((6-chloropyridin-3-yl)methyl)-N-ethyl-N'-methyl-2-nitroethene-1,1-diamine

Nitenpyram Impurity 2
Formula: C8H10ClN3O
199.64
RM-N250002
N-((6-chloropyridin-3-yl)methyl)-N-ethylnitrous amide

Nitenpyram Impurity 3
Formula: C10H12ClN3O3
257.67
RM-N250003
N-((6-chloropyridin-3-yl)methyl)-N-ethyl-2-nitroacetamide

Nitenpyram Impurity 4
Formula: C11H14ClN5O3
299.72
RM-N250004
(1E,2Z)-N-((6-chloropyridin-3-yl)methyl)-N-ethyl-2-(hydroxyimino)-N'-methyl-2-nitroacetimidamide

Nitenpyram(Mixture Of E/Z-Isomers)
CAS:120738-89-8
Formula: C11H15ClN4O2
270.72
RM-N250001
N-((6-chloropyridin-3-yl)methyl)-N-ethyl-N'-methyl-2-nitroethene-1,1-diamine

NITISINONE
CAS:104206-65-7
Formula: C14H10F3NO5
329.23
RM-N092000
2-(2-Nitro-4-(trifluoromethyl)benzoyl)cyclohexane-1,3-dione

NITRAZEPAM EP IMPURITY A
Formula: C15H11N3O3
281.27
RM-N092201
3-amino-6-nitro-4-phenylquinolin-2(1H)-one

Nitrazepam EP Impurity B
Formula: C13H10N2O3
242.23
RM-N092202
(2-Amino-5-nitrophenyl)(phenyl)methanone

Nitrazepam EP Impurity C
Formula: C15H11BrN2O4
363.16
RM-N092203
N-(2-Benzoyl-4-nitrophenyl)-2-bromoacetamide

NITRAZEPAM EP IMPURITY D
Formula: C23H15N3O6
429.38
RM-N092204
N-(2-benzoyl-4-nitrophenyl)-2-(1,3-dioxoisoindolin-2-yl)acetamide

NITRENDIPINE
CAS:39562-70-4
Formula: C18H20N2O6
360.37
RM-N200400
3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

NITRENDIPINE EP IMPURITY A
CAS:89267-41-4
Formula: C18H18N2O6
358.35
RM-N200401
3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate

NITRENDIPINE EP IMPURITY C
CAS:21829-28-7
Formula: C19H22N2O6
374.39
RM-N200403
Diethyl 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

NITRENDIPINE IMPURITY 12
CAS:53055-15-5
Formula: C18H20N2O6
360.36
RM-N200412
3-ethyl 5-methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nitrendipine Impurity 13
CAS:39562-29-3
Formula: C18H20N2O6
360.36
RM-N200413
3-ethyl 5-methyl 2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nitrendipine Impurity 14
Formula: C21H24N2O6
400.43
RM-N200414
3-isopropyl 5-(2-methoxyethyl) 2,6-dimethyl-4-(3-nitrosophenyl)pyridine-3,5-dicarboxylate

NITRENDIPINE IMPURITY 41
CAS:23510-18-1
Formula: C10H14ClN HCl
183.68 36.46
RM-N200441
N-benzyl-2-chloro-N-methylethanamine hydrochloride

Nitrendipine Impurity 42
CAS:89267-42-5
Formula: C17H16N2O6
344.32
RM-N200642
5-(ethoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)nicotinic acid

Nitrendipine Impurity 43
CAS:80890-07-9
Formula: C18H20N2O6
360.37
RM-N200643
3-ethyl 5-methyl (R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Nitrendipine Impurity 44
CAS:14205-46-0
Formula: C7H13NO2
143.19
RM-N200644
isopropyl 3-aminobut-2-enoate

Nitrendipine Impurity 45
CAS:85677-91-4
Formula: C14H15NO6
293.28
RM-N200645
2-methoxyethyl (E)-2-(3-nitrobenzylidene)-3-oxobutanoate

Nitrendipine Impurity 46
Formula: C18H20N2O7
376.37
RM-N200646
3-ethyl 5-methyl 3-hydroxy-6-methyl-2-methylene-4-(3-nitrophenyl)-1,2,3,4-tetrahydropyridine-3,5-dicarboxylate

Nitrendipine Impurity 47
Formula: C18H20N2O7
376.37
RM-N200647
6-ethyl 4-methyl 1,3-dimethyl-5-(3-nitrophenyl)-7-oxa-2-azabicyclo[4.1.0]hept-3-ene-4,6-dicarboxylate

NITRENDIPINE IMPURITY D
CAS:89267-43-6
Formula: C17H16N2O7
360.32
RM-N200404
5-(Ethoxycarbonyl)-2-(hydroxymethyl-6-methyl-4-(3-nitrophenyl)nicotinic Acid

NITRENDIPINE IMPURITY E
CAS:74936-73-5
Formula: C17H18N2O6
346.33
RM-N200405
5-(Ethoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid

NITRENDIPINE IMPURITY H
CAS:74936-69-9
Formula: C18H20N2O6
360.36
RM-N200408
5-(isopropoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid

Nitrendipine Impurity I
CAS:39562-22-6
Formula: C14H15NO6
293.27
RM-N200409
2-methoxyethyl 2-(3-nitrobenzylidene)-3-oxobutanoate

NITRENDIPINE IMPURITY J
CAS:40100-28-5
Formula: C7H13NO2
143.18
RM-N200410
(Z)-isopropyl 3-aminobut-2-enoate

Nitrendipine Impurity R
CAS:22502-03-0
Formula: C7H12O4
160.17
RM-N200411
2-methoxyethyl 3-oxobutanoate

NITRENDIPINE-D5
Formula: C18H15D5N2O6
365.39
RM-N200440
Nitrendipine-d5

NITROCAPHANE
CAS:54940-95-3
Formula: C14H19Cl2N3O4
364.22
RG-A262437
2-amino-3-(2-((bis(2-chloroethyl)amino)methyl)-5-nitrophenyl)propanoic acid

NITRODENAFIL
CAS:147676-99-1
Formula: C17H19N5O4
357.36
RM-N090400
5-(2-ethoxy-5-nitrophenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(4H)-one

NITROFEN
CAS:1836-75-5
Formula: C12H7Cl2NO3
284.09
RG-A260597
Nitrofen

NITROFURAL
CAS:59-87-0
Formula: C6H6N4O4
198.14
RM-R578000
2-((5-nitrofuran-2-yl)methylene)hydrazine-1-carboxamide

NITROFURANTOIN
CAS:67-20-9
Formula: C8H6N4O5
238.16
RM-N090600
NITROFURANTOIN

NITROFURANTOIN IMPURITY 2
Formula: C10H8N4O7
296.2
RM-N090602
(E)-2-(3-(((5-nitrofuran-2-yl)methylene)amino)-2,5-dioxoimidazolidin-1-yl)acetic acid

NITROFURANTOIN IMPURITY 3
Formula: C7H7N3O5
213.15
RM-N090603
(E)-(((5-nitrofuran-2-yl)methylene)amino)glycine

Nitrofurantoin Impurity 4
CAS:91447-38-0
Formula: C7H7N3O5
213.15
RM-N090604
(((5-nitrofuran-2-yl)methylene)amino)glycine

Nitrofurantoin impurity 5
CAS:1749-92-4
Formula: C10H8N4O7
296.2
RM-N090605
2-(3-(((5-nitrofuran-2-yl)methylene)amino)-2,5-dioxoimidazolidin-1-yl)acetic acid

Nitrofurantoin Impurity 7
CAS:3805-51-4
Formula: C9H10N4O6
270.2
RM-N090607
methyl N-carbamoyl-N-(((5-nitrofuran-2-yl)methylene)amino)glycinate

Nitrofurantoin Impurity 8
CAS:777-34-4
Formula: C8H7N3O3
193.16
RM-N090608
1-((furan-2-ylmethylene)amino)imidazolidine-2,4-dione

NITROFURANTOIN USP RELATED COMPOUND A
CAS:63981-22-6
Formula: C8H8N4O6
256.17
RM-N090601
N-carbamoyl-N-(((5-nitrofuran-2-yl)methylene)amino)glycine

NITROFURANTOIN-13C3
CAS:1217226-46-4
Formula: C513C3H6N4O5
241.14
RM-N090610
1-(((5-nitrofuran-2-yl)methylene)amino)imidazolidine-2,4-dione-2,4,5-13C3

Nitrogen mustard hydrochloride
CAS:55-86-7
Formula: C5H11Cl2N HCl
156.05 36.46
RM-N201800
2-chloro-N-(2-chloroethyl)-N-methylethanamine hydrochloride

Nitrosamine Impurity 9
Formula: C10H11N3O3
221.22
RM-N092809
(Z)-3-(2-nitroso-2-phenylhydrazineylidene)butanoic acid

NITROSO ANTIPYRINE
CAS:885-11-0
Formula: C11H11N3O2
217.22
RM-A142005
1,5-dimethyl-4-nitroso-2-phenyl-1H-pyrazol-3(2H)-one

NITROSOBENZENE
CAS:586-96-9
Formula: C6H5NO
107.11
RG-P022553
NITROSOBENZENE

NITROSOGUANIDINE
CAS:674-81-7
Formula: CH4N4O
88.07
RG-A261314
1-nitrosoguanidine

NITROUS ACID
CAS:7782-77-6
Formula: HNO2
47.01
RG-A261936
nitrous acid

NITROUS AMIDE
CAS:35576-91-1
Formula: H2N2O
46.03
RG-A263403
nitrous amide

NITROVIN HCL
CAS:804-36-4
Formula: C14H12N6O6.HCl
396.74
RM-N202200
Difurazone Hydrochloride; Nitrovin Hydrochloride; 1-[3-(5-nitro-2-furyl)-1-[2-(5-nitro-2-2furyl)vinyl]alylidenamino]guanidin Hydrochloride

NITROVIN HYDROCHLORIDE
CAS:2315-20-0
Formula: C14H12N6O6 HCl
396.74
RG-A260633
Nitrovin Hydrochloride

NIVALENOL
CAS:23282-20-4
Formula: C15H20O7
312.32
RM-D050902
(2R,2'S,3R,4S,5S,5aR,6S,9aR)-3,4,6-trihydroxy-5a-(hydroxymethyl)-5,8-dimethyl-2,3,4,5,5a,6-hexahydrospiro[2,5-methanobenzo[b]oxepine-10,2'-oxiran]-7(9aH)-one

NIZATIDINE
CAS:76963-41-2
Formula: C12H21N5O2S2
331.46
RM-N262000
N-(2-[(2-[(Dimethylamino)methyl]thiazol-4-yl)methylthio]ethyl)-N-methyl-2-nitroethene-1,1-diamine