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Levonorgestrel Impurity 13
Formula: C38H54O4
574.85
RM-L221533
Levonorgestrel Impurity 13

LEVONORGESTREL IMPURITY 14
CAS:848-04-4
Formula: C20H26O2
298.43
RM-L221534
(8R,9S,13S,14S)-13-ethyl-3-methoxy-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one

LEVONORGESTREL IMPURITY 15
Formula: C20H26O2
298.43
RM-L221535
(13S,14S,17S)-13-ethyl-3-methoxy-4,11,12,13,14,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-ol

LEVONORGESTREL IMPURITY 16
Formula: C20H28O2
300.44
RM-L221536
(8R,9S,13S,14R,17S)-13-ethyl-3-methoxy-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-ol

LEVONORGESTREL IMPURITY 17
Formula: C20H28O2
300.44
RM-L221537
(9S,13S,14S,17S)-13-ethyl-3-methoxy-4,6,9,11,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-ol

LEVONORGESTREL IMPURITY 18
Formula: C20H24O2
296.41
RM-L221538
(13S,14S)-13-ethyl-3-methoxy-1,4,11,12,13,14,15,16-octahydro-17H-cyclopenta[a]phenanthren-17-one

Levonorgestrel Impurity 19
CAS:1337972-90-3
Formula: C20H26O2
298.43
RM-L221539
(9R,13S)-13-ethyl-3-methoxy-1,4,6,7,9,11,12,13,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one

Levonorgestrel Impurity 20
CAS:20402-62-4
Formula: C21H28O3
328.45
RM-L221540
(8S,9S,10S,13S,14S,17R)-13-ethyl-17-ethynyl-10,17-dihydroxy-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one/(8R,9R,10R,13R,14R,17S)-13-ethyl-17-ethynyl-10,17-dihydroxy-1,2,6,7,8,9,10,11,12,13,14,15,16,17

Levonorgestrel Impurity 21
Formula: C22H30O3
342.48
RM-L221541
(6S,8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-6,17-dihydroxy-6-methyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

Levonorgestrel Impurity 22
Formula: C21H24O2
308.42
RM-L221542
(9R,10R,13S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,9,10,11,12,13,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one

Levonorgestrel Impurity 24
Formula: C21H28O2
312.45
RM-L221544
(5S,8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

LEVONORGESTREL IMPURITY 9
CAS:797-64-8
Formula: C21H28O2
312.45
RM-L221529
(8S,9R,10S,13R,14R,17S)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

Levonorgestrel; Norgestimate EP Impurity B
CAS:797-63-7
Formula: C21H28O2
312.45
RM-L221500
(8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one

LEVOPIMARIC ACID
CAS:79-54-9
Formula: C20H30O2
302.45
RM-P130305
+¦-Pimaric Acid; L-Pimaric Acid; NSC 4827; l-Pimaric Acid; l-Sapietic Acid; +ö6,8(14)-Abietadienoic Acid; (-)-Levopimaric acid; 13-Isopropylpodocarpa-8(14),12-dien-15-oic Acid

LEVOSIMENDAN
CAS:141505-33-1
Formula: C14H12N6O
280.28
RM-L051900
(R)-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyl dicyanide

LEVOSIMENDAN CYANOACETAMIDE HYDRAZONE IMPURITY
CAS:274263-65-9
Formula: C14H14N6O2
298.3
RM-L051901
(R)-2-amino-N'-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2-oxoacetohydrazonoyl cyanide

LEVOSIMENDAN IMPURITY 10
CAS:139052-02-1
Formula: C13H15N3O2
245.28
RM-L051910
(R)-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)acetamide

Levosimendan Impurity 101
CAS:34861-78-4
Formula: C7H12O4
160.17
RM-L052901
4-ethoxy-2-methyl-4-oxobutanoic acid

Levosimendan Impurity 102
Formula: C14H17N3O3
275.31
RM-L052902
3-(6-(4-aminophenyl)-5-methyl-3-oxo-2,3,4,5-tetrahydropyridazin-4-yl)propanoic acid

Levosimendan Impurity 103
Formula: C18H20N6O5
400.4
RM-L052903
3-Acetoxy-3-imino-2-{2-[p-(4-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridazinyl)phenyl]hydrazono}propionimidoyl acetate

Levosimendan Impurity 104
Formula: C28H24N12O2
560.58
RM-L052904
(Z)-6-cyano-5-imino-N,2-bis(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2,5-dihydro-1,2,4-triazine-3-carbohydrazonoyl cyanide

Levosimendan Impurity 105
CAS:2304672-92-0
Formula: C16H21NO5
307.35
RM-L052905
diethyl 2-(1-(4-aminophenyl)-1-oxopropan-2-yl)malonate

Levosimendan Impurity 106
CAS:1803745-09-6
Formula: C9H10BrNO
228.09
RM-L052906
1-(4-aminophenyl)-2-bromopropan-1-one

Levosimendan Impurity 107
Formula: C22H22N6O3
418.46
RM-L052907
5-methyl-4-((4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)amino)-6-(4-nitrosophenyl)-4,5-dihydropyridazin-3(2H)-one

Levosimendan Impurity 108
Formula: C22H22N6O3
418.46
RM-L052908
5-methyl-5-((4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)amino)-6-(4-nitrosophenyl)-4,5-dihydropyridazin-3(2H)-one

Levosimendan Impurity 109
Formula: C22H22N4O2
374.44
RM-L052909
6-(4-(2-(4-aminophenyl)-3-methyl-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

LEVOSIMENDAN IMPURITY 11
CAS:144238-75-5
Formula: C14H12N6O
280.28
RM-L051911
(S)-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyl dicyanide

Levosimendan Impurity 110
Formula: C14H15NO6
293.28
RM-L052910
2-(1-(4-acetamidophenyl)-1-oxopropan-2-yl)malonic acid

Levosimendan Impurity 111
Formula: C12H13NO5
251.24
RM-L052911
2-(1-(4-aminophenyl)-1-oxopropan-2-yl)malonic acid

Levosimendan Impurity 112
CAS:1011-46-7
Formula: C10H10N2O
174.2
RM-L052912
6-Phenyl-4,5-dihydropyridazin-3(2H)-one

Levosimendan Impurity 113
CAS:3707-98-0
Formula: C12H12ClN3O
249.7
RM-L052913
4-Chloro-5-(dimethylamino)-2-phenylpyridazin-3(2H)-one

LEVOSIMENDAN IMPURITY 12
Formula: C14H12N4O3
284.27
RM-L051912
4-(4-(2-(dicyanomethylene)hydrazinyl)phenyl)-3-methyl-4-oxobutanoic acid

LEVOSIMENDAN IMPURITY 13
CAS:2290570-69-1
Formula: C11H12N2O
188.23
RM-L051913
(S)-5-methyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one

LEVOSIMENDAN IMPURITY 14
CAS:252638-01-0
Formula: C14H11N7O2
309.28
RM-L051914
(4-(2-azido-3-methyl-5-oxotetrahydrofuran-2-yl)phenyl)carbonohydrazonoyl dicyanide

LEVOSIMENDAN IMPURITY 15
CAS:52240-42-3
Formula: C13H17N3O
231.29
RM-L051915
6-(4-(ethylamino)phenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

LEVOSIMENDAN IMPURITY 16
CAS:131741-08-7
Formula: C14H12N6O
280.28
RM-L051916
(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyl dicyanide

LEVOSIMENDAN IMPURITY 18
CAS:36725-28-7
Formula: C11H13N3O
203.24
RM-L051918
6-(4-aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

LEVOSIMENDAN IMPURITY 19
CAS:101328-85-2
Formula: C11H13N3O
203.24
RM-L051919
(R)-6-(4-aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

LEVOSIMENDAN IMPURITY 2
Formula: C11H12N2O
188.23
RM-L051902
5-methyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one

LEVOSIMENDAN IMPURITY 20
Formula: C14H16N6O3
316.32
RM-L051920
(R)-2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazono)malonamide

LEVOSIMENDAN IMPURITY 21
Formula: C28H24N12O2
560.57
RM-L051921
(E)-3-(cyano((E)-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)diazenyl)methylene)-5-imino-2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile

Levosimendan Impurity 22
Formula: C14H11N7O2
309.28
RM-L051922
(4-((2R,3R)-2-azido-3-methyl-5-oxotetrahydrofuran-2-yl)phenyl)carbonohydrazonoyl dicyanide

Levosimendan Impurity 23
Formula: C14H11N7O2
309.28
RM-L051923
(4-((2S,3R)-2-azido-3-methyl-5-oxotetrahydrofuran-2-yl)phenyl)carbonohydrazonoyl dicyanide

Levosimendan Impurity 24
Formula: C14H14N6O2
298.31
RM-L051924
(E)-2-amino-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2-oxoacetohydrazonoyl cyanide

Levosimendan Impurity 25
CAS:131741-36-1
Formula: C14H10N6O
278.28
RM-L051925
N-(4-(4-methyl-6-oxo-1,6-dihydropyridazin-3-yl)phenyl)carbonohydrazonoyl dicyanide

Levosimendan Impurity 26
CAS:36725-27-6
Formula: C13H15N3O2
245.28
RM-L051926
N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)acetamide

Levosimendan Impurity 27
CAS:103416-88-2
Formula: C11H12N2O2
204.23
RM-L051927
6-(4-hydroxyphenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Levosimendan Impurity 28
Formula: C14H16N6O3
316.32
RM-L051928
2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazineylidene)malonamide

Levosimendan Impurity 29
Formula: C18H22N4O5
374.4
RM-L051929
diethyl 2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazineylidene)malonate

LEVOSIMENDAN IMPURITY 3
CAS:618458-79-0
Formula: C30H30N12O3
606.64
RM-L051903
(E)-4-amino-6-ethoxy-N-(4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-5-((E)-(4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)diazenyl)pyrimidine-2-carbohydrazonoyl cyanide

Levosimendan Impurity 30
CAS:42075-29-6
Formula: C11H13NO3
207.23
RM-L051930
4-(4-aminophenyl)-3-methyl-4-oxobutanoic acid

Levosimendan Impurity 31
Formula: C22H23N7O2
417.47
RM-L051931
(E)-6,6'-(triaz-1-ene-1,3-diylbis(4,1-phenylene))bis(5-methyl-4,5-dihydropyridazin-3(2H)-one)

Levosimendan Impurity 32
Formula: C22H23N7O2
417.47
RM-L051932
(5R,5'R)-6,6'-(((E)-triaz-1-ene-1,3-diyl)bis(4,1-phenylene))bis(5-methyl-4,5-dihydropyridazin-3(2H)-one)

Levosimendan Impurity 33
Formula: C14H11N7O2
309.29
RM-L051933
(R)-N'-(dicyanomethylene)-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)nitrous hydrazide

Levosimendan Impurity 34
Formula: C30H31N12O3
607.66
RM-L051934
(Z)-6-ethoxy-4-imino-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-5-((E)-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)diazenyl)-1,6-dihydro-4l5-pyrimidine-2-carbohydrazonoyl cyanide

Levosimendan Impurity 35
CAS:1630760-90-5
Formula: C11H11ClN2O
222.67
RM-L051935
(R)-6-(4-chlorophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Levosimendan Impurity 36
Formula: C11H14N2O2
206.25
RM-L051936
4-(4-aminophenyl)-3-methyl-4-oxobutanamide

Levosimendan Impurity 37
Formula: C29H25N11O2
559.59
RM-L051937
3-((Z)-1-cyano-2-((4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)amino)vinyl)-5-imino-2-(4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2,5-dihydro-1,2,4-triazine-6-carbonitrile

Levosimendan Impurity 38
Formula: C14H11N7O2
309.29
RM-L051938
N-(4-(4-methyl-1-nitroso-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyl dicyanide

Levosimendan Impurity 39
Formula: C14H11N7O2
309.29
RM-L051939
N'-(dicyanomethylene)-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)nitrous hydrazide

Levosimendan Impurity 4(Mixture Of Z And E Isomers)
Formula: C16H17N5O3
327.34
RM-L051904
(R,E)-ethyl 2-cyano-2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazono)acetate

Levosimendan Impurity 40
Formula: C14H10N8O3
338.29
RM-L051940
N'-(dicyanomethylene)-N-(4-(4-methyl-1-nitroso-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)nitrous hydrazide

Levosimendan Impurity 41
Formula: C11H11N3O3
233.23
RM-L051941
5-methyl-6-(4-nitrophenyl)-4,5-dihydropyridazin-3(2H)-one

Levosimendan Impurity 42
Formula: C11H11N3O2
217.23
RM-L051942
5-methyl-6-(4-nitrosophenyl)-4,5-dihydropyridazin-3(2H)-one

Levosimendan Impurity 43
CAS:36725-26-5
Formula: C13H15NO4
249.27
RM-L051943
4-(4-acetamidophenyl)-3-methyl-4-oxobutanoic acid

Levosimendan Impurity 44
Formula: C15H13N5O
279.3
RM-L051944
2-(((4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)amino)methylene)malononitrile

Levosimendan Impurity 45
Formula: C16H17N5O3
327.34
RM-L051945
ethyl (E)-2-cyano-2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazineylidene)acetate

Levosimendan Impurity 46
Formula: C16H17N5O3
327.34
RM-L051946
ethyl (Z)-2-cyano-2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazineylidene)acetate

Levosimendan Impurity 47
Formula: C14H14N6O2
298.31
RM-L051947
(Z)-2-amino-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2-oxoacetohydrazonoyl cyanide

Levosimendan Impurity 48
Formula: C30H30N12O3
606.65
RM-L051948
(E)-6-ethoxy-4-imino-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-5-((E)-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)diazenyl)-1,4-dihydropyrimidine-2-carbohydrazonoyl cyanide

Levosimendan Impurity 49
Formula: C28H23N11O3
561.57
RM-L051949
(2E,4Z)-2-(cyano((E)-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)diazenyl)methylene)-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2H-1,3-oxazete-4-carbohydrazonoyl cyanide

LEVOSIMENDAN IMPURITY 5
CAS:101328-84-1
Formula: C11H13N3O
203.24
RM-L051905
(S)-6-(4-aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Levosimendan Impurity 50
Formula: C28H24N12O2
560.58
RM-L051950
(2Z,4Z)-4-(cyano((E)-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)diazenyl)methylene)-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-1,4-dihydro-1,3-diazete-2-carbohydrazonoyl cyanide

Levosimendan Impurity 51
Formula: C14H14N4O5
318.29
RM-L051951
2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazineylidene)malonic acid

Levosimendan Impurity 52
CAS:131741-37-2
Formula: C14H14N6O2
298.31
RM-L051952
2-amino-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2-oxoacetohydrazonoyl cyanide

Levosimendan Impurity 53
CAS:81937-39-5
Formula: C18H23NO6
349.38
RM-L051953
Diethyl 2-(1-(4-acetamidophenyl)-1-oxopropan-2-yl)malonate

Levosimendan Impurity 54
Formula: C15H15N5O3
313.32
RM-L051954
methyl 2-cyano-2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazineylidene)acetate

Levosimendan Impurity 55
Formula: C15H15N5O3
313.32
RM-L051955
methyl (R)-2-cyano-2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazineylidene)acetate

Levosimendan Impurity 56
Formula: C15H15N5O3
313.32
RM-L051956
methyl (S)-2-cyano-2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazineylidene)acetate

Levosimendan Impurity 57
Formula: C13H15N3O2
245.28
RM-L051957
(S)-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)acetamide

Levosimendan Impurity 58
Formula: C18H22N4O5
374.4
RM-L051958
diethyl (R)-2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazineylidene)malonate

Levosimendan Impurity 59
Formula: C18H22N4O5
374.4
RM-L051959
diethyl (S)-2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazineylidene)malonate

LEVOSIMENDAN IMPURITY 6
Formula: C15H15N5O3
313.31
RM-L051906
(E)-ethyl 2-cyano-2-(2-(4-(6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazono)acetate

Levosimendan Impurity 60
Formula: C15H16N6O4
344.33
RM-L051960
(S)-2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazineylidene)-3-oxosuccinamide

Levosimendan Impurity 61
CAS:63514-63-6
Formula: C11H12BrNO2
270.13
RM-L051961
N-(4-(2-bromopropanoyl)phenyl)acetamide

Levosimendan Impurity 62
Formula: C22H23N7O2
417.47
RM-L051962
(5S,5'S)-6,6'-(triaz-1-ene-1,3-diylbis(4,1-phenylene))bis(5-methyl-4,5-dihydropyridazin-3(2H)-one)

Levosimendan Impurity 63
Formula: C11H14N4O
218.26
RM-L051963
(R)-6-(4-hydrazineylphenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Levosimendan Impurity 64
Formula: C13H17N3O
231.3
RM-L051964
(R)-6-(4-(ethylamino)phenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Levosimendan Impurity 65
Formula: C13H17N3O
231.3
RM-L051965
(S)-6-(4-(ethylamino)phenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Levosimendan Impurity 66
Formula: C11H12N2O2
204.23
RM-L051966
(S)-6-(4-hydroxyphenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Levosimendan Impurity 67
Formula: C14H16N6O3
316.32
RM-L051967
(S)-2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazineylidene)malonamide

Levosimendan Impurity 68
Formula: C11H12N2O
188.23
RM-L051968
(R)-5-methyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one

Levosimendan Impurity 69
Formula: C14H14N6O2
298.31
RM-L051969
(R,E)-2-amino-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2-oxoacetohydrazonoyl cyanide

LEVOSIMENDAN IMPURITY 7
Formula: C15H13N5O
279.3
RM-L051907
(S)-2-(((4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)amino)methylene)malononitrile

Levosimendan Impurity 70
Formula: C28H23N11O3
561.57
RM-L051970
(2E,4Z)-2-(cyano((E)-(4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)diazenyl)methylene)-N-(4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2H-1,3-oxazete-4-carbohydrazonoyl cyanide

Levosimendan Impurity 71
CAS:131741-05-4
Formula: C15H15N5O3
313.32
RM-L051971
ethyl 2-cyano-2-(2-(4-(6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazineylidene)acetate

Levosimendan Impurity 72
Formula: C14H14N4O4
302.29
RM-L051972
(R,Z)-2-(2-(4-(4-amino-2-methyl-4-oxobutanoyl)phenyl)hydrazineylidene)-2-cyanoacetic acid

Levosimendan Impurity 73
Formula: C11H11ClN4O
250.69
RM-L051973
(R)-4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)benzenediazonium chloride

Levosimendan Impurity 74
Formula: C11H12N4O2
232.24
RM-L051974
(R)-6-(4-aminophenyl)-5-methyl-2-nitroso-4,5-dihydropyridazin-3(2H)-one

Levosimendan Impurity 75
Formula: C14H11N7O2
309.29
RM-L051975
(R)-N-(4-(4-methyl-1-nitroso-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyl dicyanide

Levosimendan Impurity 76
Formula: C14H10N8O3
338.29
RM-L051976
(R)-N'-(dicyanomethylene)-N-(4-(4-methyl-1-nitroso-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)nitrous hydrazide

Levosimendan Impurity 77
Formula: C16H16N6O3
340.34
RM-L051977
(R,Z)-acetic (R,Z)-2-cyano-2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazineylidene)acetimidic anhydride

Levosimendan Impurity 78
CAS:16960-49-9
Formula: C11H13NO2
191.23
RM-L051978
N-(4-Propionylphenyl)acetamide

Levosimendan Impurity 79
Formula: C11H13NO3
207.23
RM-L051979
4-(2-aminophenyl)-3-methyl-4-oxobutanoic acid

LEVOSIMENDAN IMPURITY 8
Formula: C11H12N2O2
204.23
RM-L051908
(R)-6-(4-hydroxyphenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Levosimendan Impurity 80
Formula: C28H24N12O2
560.58
RM-L051980
(2Z,4Z)-4-(cyano((E)-(4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)diazenyl)methylene)-N-(4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-1,4-dihydro-1,3-diazete-2-carbohydrazonoyl cyanide

Levosimendan Impurity 81
Formula: C28H24N12O2
560.58
RM-L051981
(Z)-6-cyano-5-imino-N,2-bis(4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2,5-dihydro-1,2,4-triazine-3-carbohydrazonoyl cyanide

Levosimendan Impurity 82
CAS:13051-16-6
Formula: C12H13NO5
251.24
RG-A262959
ethyl 2-methyl-3-(4-nitrophenyl)-3-oxopropanoate

Levosimendan Impurity 83
CAS:1284376-94-8
Formula: C11H11NO5
237.21
RG-A262960
3-methyl-4-(4-nitrophenyl)-4-oxobutanoic acid

Levosimendan Impurity 84
Formula: C16H19NO7
337.33
RG-A262958
diethyl 2-methyl-2-(4-nitrobenzoyl)succinate

Levosimendan Impurity 85
Formula: C14H13NO7
307.26
RG-A262957
2,2,5-trimethyl-5-(4-nitrobenzoyl)-1,3-dioxane-4,6-dione

Levosimendan Impurity 86
Formula: C13H11NO7
293.23
RG-A262956
2,2-dimethyl-5-(4-nitrobenzoyl)-1,3-dioxane-4,6-dione

Levosimendan Impurity 87
Formula: C28H24N12O2
560.58
RM-L051987
(E)-3-(cyano((E)-(4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)diazenyl)methylene)-5-imino-2-(4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile

Levosimendan Impurity 88
CAS:244077-42-7
Formula: C11H14N4O
218.26
RM-L051988
6-(4-hydrazineylphenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Levosimendan Impurity 89
Formula: C11H11ClN2O
222.67
RM-L051989
6-(4-chlorophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

LEVOSIMENDAN IMPURITY 9
Formula: C16H17N5O3
327.34
RM-L051909
(R,Z)-ethyl 2-cyano-2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazono)acetate

Levosimendan Impurity 90
CAS:52241-03-9
Formula: C11H13NO3
207.23
RM-L051990
4-(3-aminophenyl)-3-methyl-4-oxobutanoic acid

Levosimendan Impurity 91
Formula: C13H14N4O3
274.28
RM-L051991
N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-N-nitrosoacetamide

Levosimendan Impurity 92
Formula: C11H12N4O2
232.24
RM-L051992
N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)nitrous amide

Levosimendan Impurity 93
Formula: C14H12N6O
280.29
RM-L051993
N-(2-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyl dicyanide

Levosimendan Impurity 94
Formula: C11H13N3O
203.25
RM-L051994
6-(2-aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Levosimendan Impurity 95
Formula: C11H13N3O
203.25
RM-L051995
6-(3-aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

Levosimendan Impurity 96
Formula: C14H12N6O
280.29
RM-L051996
N-(3-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyl dicyanide

Levosimendan Impurity 97
Formula: C14H10N6O
278.28
RM-L051997
N-(4-(6-hydroxy-4-methylpyridazin-3-yl)phenyl)carbonohydrazonoyl dicyanide

Levosimendan Impurity 98
CAS:42075-21-8
Formula: C13H14N2O2
230.27
RM-L051998
N-(4-(3-cyano-2-methylpropanoyl)phenyl)acetamide

Levosimendan Impurity 99
Formula: C7H12O4
160.17
RM-L051999
(S)-4-ethoxy-2-methyl-4-oxobutanoic acid

Levosimendan Impurity A
Formula: C14H13N5O3
299.29
RM-A131281
(R,E)-2-cyano-2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazineylidene)acetic acid

LEVOTHYROXINE ACETAMIDE IMPURITY
CAS:176258-88-1
Formula: C14H9I4NO3
746.84
RM-L202415
2-(4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetamide

LEVOTHYROXINE EP IMPURITY A
CAS:6893-02-3
Formula: C15H12I3NO4
650.97
RM-L202401
(2S)-2-Amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid

LEVOTHYROXINE EP IMPURITY B
CAS:1628720-66-0
Formula: C15H11ClI3NO4
685.42
RM-L202402
(2S)-2-Amino-3-[4-(3-chloro-4-hydroxy-5-iodophenoxy)-3,5-diiodophenyl] propanoic acid

Levothyroxine EP Impurity C; Liothyronine EP Impurity C
CAS:51-24-1
Formula: C14H9I3O4
621.93
RM-L202403
[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acid

Levothyroxine EP Impurity D; Liothyronine EP Impurity D
CAS:67-30-1
Formula: C14H8I4O4
747.83
RM-L202404
[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic acid

Levothyroxine EP Impurity E; Liothyronine EP Impurity E
CAS:1041-01-6
Formula: C15H13I2NO4
525.08
RM-L202405
(2S)-2-Amino-3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]-propanoic acid

LEVOTHYROXINE EP IMPURITY F
CAS:911661-90-0
Formula: C21H13I6NO5
1120.76
RM-L202406
(2S)-2-Amino-3-[4-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenoxy]-3,5-diiodophenyl]propanoic acid

LEVOTHYROXINE EP IMPURITY H
CAS:2055-97-2
Formula: C13H6I4O4
733.8
RM-L202407
4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzoic acid

LEVOTHYROXINE EP IMPURITY I
CAS:2016-06-0
Formula: C13H6I4O3
717.8
RM-L202410
4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzaldehyde

LEVOTHYROXINE EP IMPURITY J
CAS:4604-41-5
Formula: C15H13I2NO4
525.08
RM-L202411
(S)-2-amino-3-(4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl)propanoic acid

LEVOTHYROXINE EP IMPURITY K
CAS:5817-39-0
Formula: C15H12I3NO4
650.97
RM-L202412
(S)-2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl)propanoic acid

LEVOTHYROXINE ETHYL ESTER
CAS:76353-71-4
Formula: C17H15I4NO4
804.92
RM-L202408
Ethyl 2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo phenyl) propanoate

LEVOTHYROXINE IMPURITY 17
Formula: C21H15I4NO9
932.96
RM-L202417
(2S)-2-(3-(carboxymethyl)-3-hydroxy-2,5-dioxopyrrolidin-1-yl)-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic acid

LEVOTHYROXINE IMPURITY 18
CAS:70-78-0
Formula: C9H10INO3
307.09
RM-L202418
(S)-2-amino-3-(4-hydroxy-3-iodophenyl)propanoic acid

LEVOTHYROXINE IMPURITY 19
CAS:51-26-3
Formula: C15H11I3O4
635.96
RM-L202419
3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoic acid

LEVOTHYROXINE IMPURITY 20
CAS:7069-47-8
Formula: C15H10I4O5
777.85
RM-L202420
2-hydroxy-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic acid

LEVOTHYROXINE IMPURITY 21
CAS:909279-46-5
Formula: C15H11ClI3NO4
685.42
RM-L202421
(S)-2-amino-3-(3-chloro-4-(4-hydroxy-3,5-diiodophenoxy)-5-iodophenyl)propanoic acid

LEVOTHYROXINE IMPURITY 22
CAS:2230724-39-5
Formula: C15H13I4NO2
746.89
RM-L202422
2-(4-(3,5-Diiodo-4-methoxyphenoxy)-3,5-diiodophenyl)ethanamine

LEVOTHYROXINE IMPURITY 23
Formula: C15H11I4NO5
792.87
RM-L202423
(2S)-2-amino-3-hydroxy-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic acid

LEVOTHYROXINE IMPURITY 24
CAS:2088032-78-2
Formula: C14H9I4NO3
746.84
RM-L202424
4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methylbenzamide

LEVOTHYROXINE IMPURITY 25
CAS:2088032-52-2
Formula: C16H14I4N2O3
789.91
RM-L202425
(S)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-N-methylpropanamide

LEVOTHYROXINE IMPURITY 26
CAS:1155-40-4
Formula: C14H10I2O4
496.04
RM-L202426
2-(4-(4-Hydroxyphenoxy)-3,5-diiodophenyl)acetic acid

LEVOTHYROXINE IMPURITY 27
CAS:2278-95-7
Formula: C15H8I4O4
759.84
RM-L202427
(E)-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acrylic acid

LEVOTHYROXINE IMPURITY 28
CAS:3571-49-1
Formula: C14H11I4NO2
732.86
RM-L202428
4-(4-(2-aminoethyl)-2,6-diiodophenoxy)-2,6-diiodophenol

LEVOTHYROXINE IMPURITY 29
CAS:51-49-0
Formula: C15H11I4NO4
776.87
RM-L202429
(R)-2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic acid

LEVOTHYROXINE IMPURITY 30
Formula: C15H12O4
256.26
RM-L202430
(E)-3-(4-(4-hydroxyphenoxy)phenyl)acrylic acid

LEVOTHYROXINE IMPURITY 31
CAS:92151-30-9
Formula: C14H9I3O4
621.94
RM-L202431
2-(4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl)acetic acid

Levothyroxine Impurity 32(Dimer)
Formula: C30H18I8N2O6
1517.72
RM-L202432
3,6-bis(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzyl)piperazine-2,5-dione

LEVOTHYROXINE IMPURITY 33
CAS:4367-89-9
Formula: C16H13I4NO4
790.9
RM-L202433
(S)-2-amino-3-(4-(3,5-diiodo-4-methoxyphenoxy)-3,5-diiodophenyl)propanoic acid

LEVOTHYROXINE IMPURITY 34
CAS:149113-40-6
Formula: C18H17I4NO4
818.95
RM-L202434
isopropyl (S)-2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate

LEVOTHYROXINE IMPURITY 35
CAS:30804-52-5
Formula: C19H17I4NO5
846.96
RM-L202435
ethyl (S)-2-acetamido-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate

LEVOTHYROXINE IMPURITY 36
Formula: C15H11ClI3NO5
701.42
RM-L202436
(2S)-2-amino-3-(3-chloro-4-(4-hydroxy-3,5-diiodophenoxy)-5-iodophenyl)-3-hydroxypropanoic acid

LEVOTHYROXINE IMPURITY 37
Formula: C25H19I6NO6
1190.85
RM-L202437
ethyl 2-acetamido-3-(4-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate

LEVOTHYROXINE IMPURITY 38
CAS:77667-01-7
Formula: C15H11BrI3NO4
729.87
RM-L202438
(S)-2-amino-3-(4-(3-bromo-4-hydroxy-5-iodophenoxy)-3,5-diiodophenyl)propanoic acid

LEVOTHYROXINE IMPURITY 39
Formula: C13H16INO4
377.18
RM-L202439
ethyl (S)-2-acetamido-3-(4-hydroxy-3-iodophenyl)propanoate

LEVOTHYROXINE IMPURITY 40
CAS:1158-10-7
Formula: C15H12I2O4
510.07
RM-L202440
3-(4-(4-hydroxyphenoxy)-3,5-diiodophenyl)propanoic acid

LEVOTHYROXINE IMPURITY 41
Formula: C15H12I3NO4
650.98
RM-L202441
2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl)propanoic acid

LEVOTHYROXINE IMPURITY 42
Formula: C14H9I3O3
605.94
RM-L202442
2-(4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl)acetaldehyde

LEVOTHYROXINE IMPURITY 43
Formula: C14H8I4O3
731.83
RM-L202443
2-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetaldehyde

LEVOTHYROXINE IMPURITY 44
CAS:58437-19-7
Formula: C15H12BrI2NO4
603.98
RM-L202444
(S)-2-amino-3-(4-(3-bromo-4-hydroxyphenoxy)-3,5-diiodophenyl)propanoic acid

LEVOTHYROXINE IMPURITY 45
Formula: C33H45I4NO5
1043.34
RM-L202445
(S)-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-2-stearamidopropanoic acid

LEVOTHYROXINE IMPURITY 46
Formula: C33H45I4NO5
1043.34
RM-L202446
(S)-2-amino-3-(4-(3,5-diiodo-4-(stearoyloxy)phenoxy)-3,5-diiodophenyl)propanoic acid

LEVOTHYROXINE IMPURITY 47
Formula: C30H31I4NO5
993.2
RM-L202447
(S,E)-2-((3,5-di-tert-butyl-4-hydroxybenzylidene)amino)-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic acid

LEVOTHYROXINE IMPURITY 48
Formula: C17H13I4NO4
802.91
RM-L202448
(S,E)-2-(ethylideneamino)-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic acid

LEVOTHYROXINE IMPURITY 49
CAS:124755-19-7
Formula: C15H22O2
234.34
RM-L202449
2-(tert-butyl)-6-(1-hydroxy-2-methylpropan-2-yl)-4-methylenecyclohexa-2,5-dien-1-one

LEVOTHYROXINE IMPURITY 50
Formula: C19H15I4NO9
908.94
RM-L202450
(2R,3R)-4-(((S)-1-carboxy-2-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)ethyl)amino)-2,3-dihydroxy-4-oxobutanoic acid

LEVOTHYROXINE LACTOSE ADDUCT
Formula: C27H31I4NO14
1101.16
RM-L202416
Levothyroxine Lactose Adduct

LEVOTHYROXINE METHYL ESTER
CAS:32180-11-3
Formula: C16H13I4NO4
790.9
RM-L202409
Methyl 2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo phenyl) propanoate

LEVOTHYROXINE N-FORMYL IMPURITY
CAS:671235-41-9
Formula: C16H11I4NO5
804.88
RM-L202414
(S)-2-formamido-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic acid

Levothyroxine Sodium; Liothyronine Sodium EP Impurity A
CAS:25416-65-3
Formula: C15H11I4NO4*Na*H2O
776.87*22.99*18.02
RM-L202400
L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt, hydrate

LEVOTHYROXINE T4-HYDROXYACETIC ACID
CAS:93647-48-4
Formula: C14H8I4O5
763.83
RM-L202413
2-Hydroxy-2-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetic acid

LEXITHROMYCIN
CAS:53066-26-5
Formula: C38H70N2O13
762.97
RM-L051800
(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(methox

LICARBAZEPINE
CAS:29331-92-8
Formula: C15H14N2O2
254.28
RM-L090300
10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide

Licarbazepine Impurity 10
Formula: C18H18N2O3
310.35
RM-L090310
(S)-5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl propionate

Licarbazepine Impurity 11
Formula: C16H13NO2
251.29
RM-L090311
5-acetyl-5,11-dihydro-10H-dibenzo[b,f]azepin-10-one

Licarbazepine Impurity 12
Formula: C19H18N2O4
338.36
RM-L090312
(S)-5-(acetylcarbamoyl)-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl acetate

Licarbazepine Impurity 13
CAS:75272-34-3
Formula: C14H10BrN
272.15
RM-L090313
10-bromo-5H-dibenzo[b,f]azepine

Licarbazepine Impurity 14
Formula: C15H11ClN2O
270.72
RM-L090314
10-chloro-5H-dibenzo[b,f]azepine-5-carboxamide

Licarbazepine Impurity 15
CAS:4014-77-1
Formula: C14H13NO
211.26
RM-L090315
10,11-Dihydro-5H-dibenzo[b,f]azepin-10-ol

Licarbazepine Impurity 2
Formula: C16H15NO2
253.3
RM-L090302
(S)-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl acetate

Licarbazepine Impurity 6
CAS:104746-04-5
Formula: C15H14N2O2
254.29
RM-L090306
(S)-10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide

Licarbazepine Impurity 7
Formula: C18H17NO3
295.34
RM-L090307
(S)-5-acetyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl acetate

Licarbazepine Impurity 8
CAS:35079-97-1
Formula: C15H14N2O3
270.29
RM-L090308
10,11-dihydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide

Licarbazepine Impurity 9
Formula: C16H15N3O3
297.31
RM-L090309
(S)-N-carbamoyl-10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide

LICARBAZEPINE-D4
CAS:1020719-39-4
Formula: C15H10D4N2O2
258.31
RM-L090301
Licarbazepine-D4

LICORICESAPONIN G2
CAS:118441-84-2
Formula: C42H62O17
838.93
RM-L091802
(2S,3S,4S,5R,6R)-6-(((2R,3R,4S,5S,6S)-6-carboxy-2-(((3S,4S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-carboxy-4-(hydroxymethyl)-4,6a,6b,8a,11,14b-hexamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl)oxy)-

LIDOCAINE
CAS:137-58-6
Formula: C14H22N2O
234.34
RM-L040300
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide

Lidocaine EP Impurity A; Ropivacaine EP Impurity H; Bupivacaine EP Impurity F; Mepivacaine EP Impurity A
CAS:87-62-7
Formula: C8H11N
121.18
RM-L040301
2,6-Dimethylaniline

LIDOCAINE EP IMPURITY B
CAS:2903-45-9
Formula: C14H22N2O2
250.34
RM-L040302
2-((2,6-dimethylphenyl)amino)-N,N-diethyl-2-oxoethanamine oxide

LIDOCAINE EP IMPURITY C
CAS:2198-53-0
Formula: C10H13NO
163.22
RM-L040303
N-(2,6-Dimethylphenyl)acetamide

LIDOCAINE EP IMPURITY D
CAS:7728-40-7
Formula: C12H18N2O
206.28
RM-L040304
N-(2,6-dimethylphenyl)-2-(ethylamino)acetamide

LIDOCAINE EP IMPURITY E
CAS:745798-07-6
Formula: C20H25N3O2
339.43
RM-L040305
2,2'-azanediylbis(N-(2,6-dimethylphenyl)acetamide)

LIDOCAINE EP IMPURITY F
CAS:142713-08-4
Formula: C14H22N2O
234.34
RM-L040306
2-(Diethylamino)-N-(2,3-dimethylphenyl)acetamide

LIDOCAINE EP IMPURITY G
CAS:42459-30-3
Formula: C13H20N2O
220.31
RM-L040307
N-(2,6-dimethylphenyl)-2-(isopropylamino)acetamide

LIDOCAINE EP IMPURITY H
CAS:1131-01-7
Formula: C10H12ClNO
197.67
RM-L040308
2-chloro-N-(2,6-dimethylphenyl)acetamide

LIDOCAINE EP IMPURITY I
CAS:17289-53-1
Formula: C14H22N2O
234.34
RM-L040309
2-(Diethylamino)-N-(2,4-dimethylphenyl)acetamide

LIDOCAINE EP IMPURITY J
CAS:857570-37-7
Formula: C14H22N2O
234.34
RM-L040310
2-(Diethylamino)-N-(2,5-dimethylphenyl)acetamide

LIDOCAINE HYDROCHLORIDE EP IMPURITY K
CAS:74634-66-5
Formula: C13H20N2O
220.31
RM-L040311
N-(2,6-dimethylphenyl)-2-(ethyl(methyl)amino)acetamide

LIDOCAINE IMPURITY 1
CAS:294852-91-8
Formula: C18H22N2O
282.38
RM-L040327
N-(2,6-dimethylphenyl)-2-((2,6-dimethylphenyl)amino)acetamide

LIDOCAINE IMPURITY 10
Formula: C15H22N2O
246.35
RM-L040336
(2R,5R)-2,5-dimethyl-1-propyl-3-(o-tolyl)imidazolidin-4-one

LIDOCAINE IMPURITY 11
Formula: C23H29N3O2
379.5
RM-L040337
(2R,4R)-N-(2,6-dimethylphenyl)-4-methyl-5-oxo-3-propyl-1-(o-tolyl)imidazolidine-2-carboxamide

LIDOCAINE IMPURITY 12
Formula: C23H29N3O2
379.5
RM-L040338
(2S,4R)-N-(2,6-dimethylphenyl)-4-methyl-5-oxo-3-propyl-1-(o-tolyl)imidazolidine-2-carboxamide

LIDOCAINE IMPURITY 13
CAS:17122-33-7
Formula: C10H11Cl2NO
232.11
RM-L040339
2,2-dichloro-N-(2,4-dimethylphenyl)acetamide

LIDOCAINE IMPURITY 14
CAS:603-02-1
Formula: C8H8N2O4
196.16
RM-L040340
1,3-Dimethyl-2,4-dinitrobenzene

LIDOCAINE IMPURITY 15
Formula: C14H18N2O
230.31
RM-L040341
3-(diethylamino)-8-methylquinolin-2(1H)-one

LIDOCAINE IMPURITY 16
CAS:18865-38-8
Formula: C10H14N2O
178.23
RM-L040342
2-Amino-N-(2,6-dimethylphenyl)acetamide

LIDOCAINE IMPURITY 17
CAS:1606-01-5
Formula: C6H13NO2
131.17
RM-L040343
2-(diethylamino)acetic acid

LIDOCAINE IMPURITY 18
CAS:2315-36-8
Formula: C6H12ClNO
149.62
RM-L040344
2-Chloro-N,N-diethylacetamide

LIDOCAINE IMPURITY 19
CAS:1596965-85-3
Formula: C11H23N3O2
229.32
RM-L040345
2-(3,3-diethylureido)-N,N-diethylacetamide

LIDOCAINE IMPURITY 2
CAS:70336-49-1
Formula: C20H22N2O2
322.4
RM-L040328
1,4-bis(2,6-dimethylphenyl)piperazine-2,5-dione

LIDOCAINE IMPURITY 20
Formula: C16H18N2O
254.33
RM-L040346
2-(phenylamino)-N-(o-tolyl)propanamide

LIDOCAINE IMPURITY 21
CAS:19422-76-5
Formula: C10H12ClNO
197.66
RM-L040347
3-chloro-N-(o-tolyl)propanamide

LIDOCAINE IMPURITY 22
Formula: C10H12ClNO
197.66
RM-L040348
1-(3-amino-4-methylphenyl)-2-chloropropan-1-one

LIDOCAINE IMPURITY 23
CAS:103-89-9
Formula: C9H11NO
149.19
RM-L040349
N-(p-tolyl)acetamide

LIDOCAINE IMPURITY 24
Formula: C11H16N2O
192.26
RM-L040350
3-(2,6-dimethylphenyl)-1,1-dimethylurea

Lidocaine Impurity 25
Formula: C14H21N3
231.34
RM-L040351
N-ethyl-N-((8-methyl-1,2-dihydroquinazolin-2-yl)methyl)ethanamine

Lidocaine Impurity 26
CAS:17880-86-3
Formula: C3H3Cl3O
161.41
RM-L040352
3,3-dichloropropanoyl chloride

LIDOCAINE IMPURITY 27
CAS:112843-97-7
Formula: C12H13Cl2NO2
274.14
RM-L040353
2-chloro-N-(2-chloroacetyl)-N-(2,6-dimethylphenyl)acetamide

Lidocaine Impurity 28
CAS:1903300-52-6
Formula: C10H11NO2
177.2
RM-L040354
N-(2,6-Dimethylphenyl)-2-oxoacetamide

Lidocaine Impurity 29
CAS:2729898-89-7
Formula: C15H22N2O
246.35
RM-L040355
(2S,5R)-2,5-dimethyl-1-propyl-3-(o-tolyl)imidazolidin-4-one

Lidocaine Impurity 3
CAS:39084-88-3
Formula: C10H11Cl2NO
232.11
RM-L040329
2,2-Dichloro-N-(2,6-dimethylphenyl)acetamide

LIDOCAINE IMPURITY 30
Formula: C15H22N2O
246.35
RM-L040356
(2R,5R)-2,5-dimethyl-1-propyl-3-(o-tolyl)imidazolidin-4-one

LIDOCAINE IMPURITY 31
Formula: C23H29N3O2
379.5
RM-L040357
(2R,4R)-N-(2,6-dimethylphenyl)-4-methyl-5-oxo-3-propyl-1-(o-tolyl)imidazolidine-2-carboxamide

Lidocaine Impurity 32
CAS:2815498-43-0
Formula: C23H29N3O2
379.5
RM-L040358
(2S,4R)-N-(2,6-dimethylphenyl)-4-methyl-5-oxo-3-propyl-1-(o-tolyl)imidazolidine-2-carboxamide

Lidocaine Impurity 33
CAS:2509057-86-5
Formula: C23H29N3O2
379.5
RM-L040359
N-(2,6-dimethylphenyl)-4-methyl-5-oxo-3-propyl-1-(o-tolyl)imidazolidine-2-carboxamide

Lidocaine Impurity 34
CAS:74709-95-8
Formula: C8H8N2O
196.16
RM-L040360
1,3-dimethyl-2,5-dinitrobenzene

Lidocaine Impurity 35
CAS:7218-02-2
Formula: C8H12N2
136.2
RM-L040361
2,6-Dimethylbenzene-1,4-diamine

Lidocaine Impurity 36
CAS:16947-63-0
Formula: C8H10N2O2
166.18
RM-L040362
2,6-Dimethyl-4-nitroaniline

Lidocaine Impurity 37
CAS:34761-82-5
Formula: C8H10N2O2
166.18
RM-L040363
3,5-Dimethyl-4-nitroaniline

Lidocaine Impurity 38
CAS:67083-28-7
Formula: C8H10N2O2
166.18
RM-L040364
2,6-Dimethyl-3-nitroaniline

Lidocaine Impurity 39
CAS:31167-04-1
Formula: C8H10N2O2
166.18
RM-L040365
2,4-dimethyl-3-nitroaniline

LIDOCAINE IMPURITY 4
CAS:39942-41-1
Formula: C14H22N2O2
250.34
RM-L040330
2-(diethylamino)-N-(4-hydroxy-2,6-dimethylphenyl)acetamide

LIDOCAINE IMPURITY 40
CAS:780037-66-3
Formula: C15H22N2O
246.35
RM-L040366
2,5-dimethyl-1-propyl-3-(o-tolyl)imidazolidin-4-one

Lidocaine Impurity 41
CAS:6967-29-9
Formula: C12H16ClNO
225.72
RM-L040367
2-Chloro-N-(2,6-diethylphenyl)acetamide

Lidocaine Impurity 42
Formula: C12H14Cl2N2O2
289.16
RM-L040368
N,N'-(2,4-dimethyl-1,3-phenylene)bis(2-chloroacetamide)

LIDOCAINE IMPURITY 43
Formula: C14H22N2O2
250.34
RM-L040369
2-((2,6-dimethylphenyl)amino)-N,N-diethyl-2-oxoethan-1-amine oxide

LIDOCAINE IMPURITY 44
Formula: C12H18N2O
206.29
RM-L040370
2-(dimethylamino)-N-(2,6-dimethylphenyl)acetamide

Lidocaine Impurity 46
CAS:1374010-02-2
Formula: C30H36N4O3
500.64
RM-L040372
2,2',2''-nitrilotris(N-(2,6-dimethylphenyl)acetamide)

Lidocaine Impurity 47
CAS:102878-74-0
Formula: C9H11NO2
165.19
RM-L040373
1-ethyl-3-methyl-2-nitrobenzene

LIDOCAINE IMPURITY 48
Formula: C14H23N2O Cl
235.35 35.45
RM-L040374
2-((2,6-dimethylphenyl)amino)-N-ethyl-N,N-dimethyl-2-oxoethan-1-aminium chloride

Lidocaine Impurity 49
Formula: C13H18N2O
218.3
RM-L040375
3-(2,6-dimethylphenyl)-1-ethylimidazolidin-4-one

LIDOCAINE IMPURITY 5
CAS:34604-55-2
Formula: C14H22N2O2
250.34
RM-L040331
2-(Diethylamino)-N-(3-hydroxy-2,6-dimethylphenyl)acetamide

Lidocaine Impurity 50
CAS:64585-19-9
Formula: C10H12ClNO2
213.66
RM-L040376
2-chloro-N-(2-(hydroxymethyl)-6-methylphenyl)acetamide

Lidocaine Impurity 51
CAS:1518616-26-6
Formula: C10H11Cl2NO
232.1
RM-L040377
2-chloro-N-(4-chloro-2,6-dimethylphenyl)acetamide

Lidocaine Impurity 54
Formula: C14H21ClN2O
268.79
RM-L040380
N-(4-chloro-2,6-dimethylphenyl)-2-(diethylamino)acetamide

Lidocaine Impurity 55
Formula: C20H24N2O3
340.42
RM-L040381
2,2'-oxybis(N-(2,6-dimethylphenyl)acetamide)

Lidocaine Impurity 56
CAS:763082-77-5
Formula: C14H20N2O
232.33
RM-L040382
5-methyl-1-propyl-3-(o-tolyl)imidazolidin-4-one

Lidocaine Impurity 57
Formula: C15H22N2O
246.35
RM-L040383
(2R,5S)-2,5-dimethyl-1-propyl-3-(o-tolyl)imidazolidin-4-one

Lidocaine Impurity 59
CAS:851528-09-1
Formula: C14H12D10N2O
244.4
RM-L040386
2-(bis(ethyl-d5)amino)-N-(2,6-dimethylphenyl)acetamide

LIDOCAINE IMPURITY 6
CAS:64585-18-8
Formula: C14H22N2O2
250.34
RM-L040332
2-(diethylamino)-N-(2-(hydroxymethyl)-6-methylphenyl)acetamide

Lidocaine Impurity 62
Formula: C14H21ClN2O
268.79
RM-L040389
2-chloro-2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide

Lidocaine Impurity 67
Formula: C15H22N2O
246.35
RM-L040394
1-(pentan-3-yl)-3-(o-tolyl)imidazolidin-4-one

Lidocaine Impurity 68
Formula: C15H22N2O
246.35
RM-L040395
3-(2,6-dimethylphenyl)-1-ethyl-2,5-dimethylimidazolidin-4-one

Lidocaine Impurity 7
Formula: C14H19N3
229.32
RM-L040333
N-ethyl-N-((8-methylquinazolin-2-yl)methyl)ethanamine

LIDOCAINE IMPURITY 8
CAS:35891-84-0
Formula: C11H16N2O HCl
192.26 36.46
RM-L040334
N-(2,6-dimethylphenyl)-2-(methylamino)acetamide hydrochloride

LIDOCAINE IMPURITY 9
Formula: C15H22N2O
246.35
RM-L040335
(2S,5R)-2,5-dimethyl-1-propyl-3-(o-tolyl)imidazolidin-4-one

Lidocaine Nitroso Impurity 52
CAS:3033377-17-9
Formula: C12H17N3O2
235.29
RM-L040378
N-(2,6-dimethylphenyl)-2-(ethyl(nitroso)amino)acetamide

Lidocaine Nitroso Impurity 53
Formula: C10H13N3O2
207.23
RM-L040379
N-(2,6-dimethylphenyl)-2-(nitrosoamino)acetamide

Lidocaine Nitroso Impurity 58
Formula: C11H15N3O2
221.26
RM-L040384
3-(2,6-dimethylphenyl)-1-ethyl-1-nitrosourea

Lidocaine Nitroso Impurity 60
Formula: C20H24N4O3
368.44
RM-L040387
2,2'-(nitrosoazanediyl)bis(N-(2,6-dimethylphenyl)acetamide)

Lidocaine Nitroso Impurity 61
Formula: C13H19N3O2
249.31
RM-L040388
N-(2,6-dimethylphenyl)-2-(isopropyl(nitroso)amino)acetamide

Lidocaine Nitroso Impurity 63
Formula: C14H21N3O2
263.34
RM-L040390
2-(diethylamino)-N-(2,6-dimethylphenyl)-N-nitrosoacetamide

Lidocaine Nitroso Impurity 64
Formula: C12H17N3O2
235.29
RM-L040391
N-(2,4-dimethylphenyl)-2-(ethyl(nitroso)amino)acetamide

Lidocaine Nitroso Impurity 65
Formula: C13H18N2O2
234.3
RM-L040392
N-(3-(2,6-dimethylphenyl)-2-oxopropyl)-N-ethylnitrous amide

Lidocaine Nitroso Impurity 66
Formula: C11H15N3O2
221.26
RM-L040393
N-(2,6-dimethylphenyl)-2-(methyl(nitroso)amino)acetamide

LIDOCAINE-D6
CAS:1215823-29-2
Formula: C14H16D6N2O
240.38
RM-L040385
N-(2,6-bis(methyl-d3)phenyl)-2-(diethylamino)acetamide

LIFITEGRAST
CAS:1025967-78-5
Formula: C29H24Cl2N2O7S
615.48
RM-L090600
(S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

LIFITEGRAST IMPURITY 1
CAS:2711953-69-2
Formula: C21H22Cl2N2O5S HCl
485.38 36.46
RM-L090601
(S)-methyl 2-(5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride

LIFITEGRAST IMPURITY 10
CAS:851785-70-1
Formula: C20H20Cl2N2O5S
471.35
RM-L090610
(S)-2-(5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 101
Formula: C29H24BrClN2O7S
659.93
RM-L090701
2-(2-(benzofuran-6-carbonyl)-5-bromo-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 102
Formula: C29H24BrClN2O7S
659.93
RM-L090702
2-(2-(benzofuran-6-carbonyl)-7-bromo-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 104
Formula: C20H19Cl2N5O4
464.3
RM-L090704
6-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl) 2-(tert-butyl) 5,7-dichloro-3,4-dihydroisoquinoline-2,6(1H)-dicarboxylate

Lifitegrast Impurity 105
Formula: C18H10O5
306.27
RM-L090705
benzofuran-6-carboxylic anhydride

Lifitegrast Impurity 106
CAS:132041-35-1
Formula: C10H8O2
160.17
RM-L090706
1H-indene-5-carboxylic acid

Lifitegrast Impurity 107
Formula: C28H30N2O4
458.56
RM-L090707
benzyl (3-(2-amino-3-(benzyloxy)-3-oxopropyl)phenyl)prolinate

Lifitegrast Impurity 108
Formula: C24H15Cl2N5O4
508.32
RM-L090708
3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl 2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylate

Lifitegrast Impurity 109
Formula: C33H32Cl2N2O7S
671.59
RM-L090709
tert-butyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

LIFITEGRAST IMPURITY 11
Formula: C22H22Cl2N2O6S
513.39
RM-L090611
(S)-2-(2-Acetyl-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 110
Formula: C19H17NO6S
387.41
RM-L090710
(S)-2-(benzofuran-6-carboxamido)-3-(4-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 111
Formula: C28H24Cl2N4O7S
631.48
RM-L090711
(R)-2-(8-amino-2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydrocinnoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 112
Formula: C13H14Cl2N2O3
317.17
RM-L090712
(5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carbonyl)alanine

Lifitegrast Impurity 113
Formula: C27H24Cl2N4O7S
619.47
RM-L090713
(R)-2-(4,6-dichloro-2-(2,3-diamino-4-formylbenzoyl)isoindoline-5-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 114
Formula: C29H22Cl2N2O8S
629.46
RM-L090714
(R)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1-oxo-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

LIFITEGRAST IMPURITY 12
CAS:77095-51-3
Formula: C9H6O3
162.14
RM-L090612
Benzofuran-6-carboxylic acid

LIFITEGRAST IMPURITY 13
CAS:2295862-00-7
Formula: C29H26N2O7S
546.59
RM-L090613
(S)-2-(2-(Benzofuran-6-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

LIFITEGRAST IMPURITY 14
CAS:2295862-24-5
Formula: C31H28Cl2N2O7S
643.53
RM-L090614
(S)-Ethyl 2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

LIFITEGRAST IMPURITY 15
CAS:2049127-88-8
Formula: C17H19NO4S HCl
333.40 36.46
RM-L090615
(R)-benzyl 2-amino-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride

LIFITEGRAST IMPURITY 16
Formula: C20H16Cl4N2O3 HCl
474.16 36.46
RM-L090616
5,7-dichloro-2-(5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid hydrochloride

LIFITEGRAST IMPURITY 17
Formula: C26H23NO6S
477.53
RM-L090617
(S)-Benzyl 2-(benzofuran-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

LIFITEGRAST IMPURITY 18
CAS:1270093-99-6
Formula: C10H13NO4S
243.28
RM-L090618
(S)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoic acid

LIFITEGRAST IMPURITY 19
CAS:1290176-71-4
Formula: C10H9Cl2NO2
246.09
RM-L090619
5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid

LIFITEGRAST IMPURITY 2
CAS:2295862-29-0
Formula: C30H26Cl2N2O7S
629.51
RM-L090602
(S)-Methyl 2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

LIFITEGRAST IMPURITY 20
Formula: C32H37Cl2N4O5S BF4
660.63 86.80
RM-L090620
(S)-N-((6-((1-(benzyloxy)-3-(3-(methylsulfonyl)phenyl)-1-oxopropan-2-yl)carbamoyl)-5,7-dichloro-3,4-dihydroisoquinolin-2(1H)-yl)(dimethylamino)methylene)-N-methylmethanaminium tetrafluoroborate

LIFITEGRAST IMPURITY 21
CAS:1865726-28-8
Formula: C17H19NO4S
333.4
RM-L090621
(S)-benzyl 2-amino-3-(4-(methylsulfonyl)phenyl)propanoate

LIFITEGRAST IMPURITY 22
CAS:90721-27-0
Formula: C9H6O3
162.14
RM-L090622
benzofuran-5-carboxylic acid

LIFITEGRAST IMPURITY 23
CAS:1194550-56-5
Formula: C29H23Cl2NO2
488.4
RM-L090623
5,7-Dichloro-2-trityl-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid

LIFITEGRAST IMPURITY 24
Formula: C17H19NO4S HCl
333.40 36.46
RM-L090624
benzyl 2-amino-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride

LIFITEGRAST IMPURITY 25
Formula: C20H22N2O6S2
450.53
RM-L090625
3,6-bis(3-(methylsulfonyl)benzyl)piperazine-2,5-dione

LIFITEGRAST IMPURITY 26
Formula: C29H24Cl2N2O7S
615.48
RM-L090626
(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(4-(methylsulfonyl)phenyl)propanoic acid

LIFITEGRAST IMPURITY 27
CAS:2322380-18-5
Formula: C29H25ClN2O7S
581.04
RM-L090627
(S)-2-(2-(benzofuran-6-carbonyl)-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

LIFITEGRAST IMPURITY 28
CAS:2322380-15-2
Formula: C29H25ClN2O7S
581.04
RM-L090628
(S)-2-(2-(benzofuran-6-carbonyl)-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

LIFITEGRAST IMPURITY 29
Formula: C30H27Cl4N3O6S
699.43
RM-L090629
(S)-2-(5,7-dichloro-2-(5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

LIFITEGRAST IMPURITY 3
CAS:1194550-65-6
Formula: C27H27Cl3N2O5S
597.94
RM-L090603
(S)-Benzyl 2-(5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride

LIFITEGRAST IMPURITY 30
Formula: C32H34Cl2N2O7S
661.59
RM-L090630
tert-butyl (R)-6-((1-(benzyloxy)-3-(3-(methylsulfonyl)phenyl)-1-oxopropan-2-yl)carbamoyl)-5,7-dichloro-3,4-dihydroisoquinoline-2(1H)-carboxylate

LIFITEGRAST IMPURITY 31
Formula: C36H30Cl2N2O7S
705.6
RM-L090631
benzyl (R)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

LIFITEGRAST IMPURITY 32
CAS:1289646-90-7
Formula: C11H10O3
190.2
RM-L090632
Ethyl benzofuran-6-carboxylate

Lifitegrast Impurity 33
CAS:1194864-16-8
Formula: C17H19NO4S
333.4
RM-L090633
benzyl (S)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoate

Lifitegrast Impurity 34
CAS:1270132-45-0
Formula: C10H13NO4S
243.28
RM-L090634
(R)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoic acid

LIFITEGRAST IMPURITY 35
CAS:851784-82-2
Formula: C15H17Cl2NO4
346.2
RM-L090635
2-(tert-Butoxycarbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid

LIFITEGRAST IMPURITY 36
CAS:89315-56-0
Formula: C9H9Cl2N
202.08
RM-L090636
5,7-dichloro-1,2,3,4-tetrahydroisoquinoline

LIFITEGRAST IMPURITY 37
CAS:14046-52-7
Formula: C9H10Cl3N.HCl
238.54 36.46
RM-L090637
2-chloro-N-(3,5-dichlorobenzyl)ethan-1-amine hydrochloride

LIFITEGRAST IMPURITY 38
Formula: C29H24Cl2N2O8S
631.48
RM-L090638
2-(5,7-dichloro-2-(1a,6b-dihydrooxireno[2,3-b]benzofuran-4-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 39
Formula: C29H26Cl2N2O9S
649.49
RM-L090639
2-(5,7-dichloro-2-(2,3-dihydroxy-2,3-dihydrobenzofuran-6-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

LIFITEGRAST IMPURITY 4
CAS:1194550-67-8
Formula: C36H30Cl2N2O7S
705.6
RM-L090604
(S)-Benzyl 2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

LIFITEGRAST IMPURITY 40
Formula: C28H26Cl2N2O8S
621.48
RM-L090640
(S)-2-(5,7-dichloro-2-(2,3-dihydrobenzofuran-6-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(dihydroxy(oxo)-l6-sulfaneyl)phenyl)propanoic acid

Lifitegrast Impurity 41
Formula: C29H24Cl2N2O7S
615.48
RM-L090641
(Z)-2-(5,7-dichloro-2-(2,3-dihydrobenzofuran-6-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)acrylic acid

Lifitegrast Impurity 42
Formula: C29H24Cl2N2O9S
647.48
RM-L090642
(Z)-2-(5,7-dichloro-2-(2,3-dihydroxy-2,3-dihydrobenzofuran-6-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)acrylic acid

Lifitegrast Impurity 43
CAS:1289646-72-5
Formula: C28H23Cl2N
444.4
RM-L090643
5,7-dichloro-2-trityl-1,2,3,4-tetrahydroisoquinoline

Lifitegrast Impurity 44
CAS:1156547-55-5
Formula: C9H5ClO2
180.59
RM-L090644
benzofuran-6-carbonyl chloride

Lifitegrast Impurity 45
Formula: C28H21BrCl2N2O5
616.29
RM-L090645
(S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-bromophenyl)propanoic acid

Lifitegrast Impurity 46
Formula: C28H24Cl2N2O9S
635.47
RM-L090646
(S)-4-(6-((1-carboxy-2-(3-(methylsulfonyl)phenyl)ethyl)carbamoyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)-2-hydroxybenzoic acid

Lifitegrast Impurity 47
Formula: C29H22Cl2N2O7S
613.46
RM-L090647
(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2-dihydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 48
Formula: C29H24Cl2N2O8S
631.48
RM-L090648
(2S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1-hydroxy-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 49
CAS:1270324-69-0
Formula: C10H13NO4S
243.28
RM-L090649
2-amino-3-(3-(methylsulfonyl)phenyl)propanoic acid

LIFITEGRAST IMPURITY 5
CAS:2271299-08-0
Formula: C29H24Cl2N2O7S
615.48
RM-L090605
(R)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 50
Formula: C29H26Cl2N2O9S
649.49
RM-L090650
(2S)-2-(5,7-dichloro-2-(2,3-dihydroxy-2,3-dihydrobenzofuran-6-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 51
Formula: C29H26Cl2N2O9S
649.49
RM-L090651
(S)-2-(2-(4-(carboxymethyl)-3-hydroxybenzoyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 52
CAS:157942-12-6
Formula: C8H7IO3
278.05
RM-L090652
methyl 3-hydroxy-4-iodobenzoate

Lifitegrast Impurity 53
CAS:478169-68-5
Formula: C13H16O3Si
248.35
RM-L090653
Methyl 3-hydroxy-4-((trimethylsilyl)ethynyl)benzoate

Lifitegrast Impurity 54
CAS:588703-29-1
Formula: C10H8O3
176.17
RM-L090654
Methyl benzofuran-6-carboxylate

Lifitegrast Impurity 55
Formula: C14H18BrNO4
344.21
RM-L090655
(R)-3-(3-bromophenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid

Lifitegrast Impurity 56
CAS:82278-73-7
Formula: C14H18BrNO4
344.21
RM-L090656
(S)-3-(3-bromophenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid

Lifitegrast Impurity 57
CAS:1289646-76-9
Formula: C15H21NO6S
343.39
RM-L090657
(S)-2-((tert-butoxycarbonyl)amino)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 58
Formula: C16H16BrNO2
334.21
RM-L090658
benzyl (S)-2-amino-3-(3-bromophenyl)propanoate

Lifitegrast Impurity 59
CAS:1289646-78-1
Formula: C22H27NO6S
433.52
RM-L090659
benzyl (S)-2-((tert-butoxycarbonyl)amino)-3-(3-(methylsulfonyl)phenyl)propanoate

LIFITEGRAST IMPURITY 6
CAS:1194550-61-2
Formula: C32H34Cl2N2O7S
661.59
RM-L090606
(S)-tert-Butyl 6-((1-(benzyloxy)-3-(3-(methylsulfonyl)phenyl)-1-oxopropan-2-yl)carbamoyl)-5,7-dichloro-3,4-dihydroisoquinoline-2(1H)-carboxylate

Lifitegrast Impurity 60
Formula: C29H22Cl2N2O8S
629.46
RM-L090660
(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1-oxo-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 62
Formula: C15H17Cl2NO4
346.2
RM-L090662
2-(tert-butoxycarbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-8-carboxylic acid

Lifitegrast Impurity 63
Formula: C16H17Cl2NO6
390.21
RM-L090663
2-(tert-butoxycarbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6,8-dicarboxylic acid

Lifitegrast Impurity 64
Formula: C14H17Cl2NO2
302.2
RM-L090664
tert-butyl 5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylate

Lifitegrast Impurity 65
Formula: C14H17Cl2NO2
302.2
RM-L090665
2-(tert-butyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid

Lifitegrast Impurity 66
Formula: C11H16F6N5OP
379.25
RM-L090666
2-(1H-benzo[d][1,2,3]triazol-1-yl)-1,1,3,3-tetramethylisouronium hexafluorophosphate(V)

Lifitegrast Impurity 67
Formula: C23H21Cl2NO4
446.32
RM-L090667
tert-butyl 2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylate

Lifitegrast Impurity 68
CAS:2641788-18-1
Formula: C39H35Cl2N3O10S2
840.74
RM-L090668
(S)-2-((S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 69
CAS:2215846-47-0
Formula: C14H17Cl2NO2
302.2
RM-L090669
tert-butyl 5,7-dichloro-3,4-dihydroisoquinoline-2(1H)-carboxylate

LIFITEGRAST IMPURITY 7
CAS:2129597-34-6
Formula: C19H13Cl2NO4
390.22
RM-L090607
2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid

Lifitegrast Impurity 70
CAS:301836-57-7
Formula: C9H8O3
164.16
RM-L090670
2,3-Dihydrobenzofuran-6-carboxylic acid

Lifitegrast Impurity 71
Formula: C20H20Cl2N2O5S
471.35
RM-L090671
(R)-2-(5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 72
Formula: C17H19NO4S
333.4
RM-L090672
benzyl (S)-2-amino-3-(2-(methylsulfonyl)phenyl)propanoate

Lifitegrast Impurity 73
Formula: C20H19NO6S
401.43
RM-L090673
methyl (S)-2-(benzofuran-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

Lifitegrast Impurity 74
Formula: C29H26Cl2N2O5S
585.5
RM-L090674
(R)-2-(benzofuran-6-carbonyl)-5,7-dichloro-N-(1-(3-(methylsulfonyl)phenyl)propan-2-yl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide

Lifitegrast Impurity 75
Formula: C10H9Cl2NO2
246.09
RM-L090675
5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-8-carboxylic acid

Lifitegrast Impurity 76
Formula: C29H24Cl2N2O8S
631.48
RM-L090676
(2S)-2-(5,7-dichloro-2-(1a,6b-dihydrooxireno[2,3-b]benzofuran-4-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 77
Formula: C28H24Cl2N2O8S
619.47
RM-L090677
(S)-2-(5,7-dichloro-2-(4-formyl-3-hydroxybenzoyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 78
CAS:166599-84-4
Formula: C9H6O3
162.14
RM-L090678
benzofuran-4-carboxylic acid

Lifitegrast Impurity 79
Formula: C28H24Cl2N2O8S
619.47
RM-L090679
(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(dihydroxy(oxo)-l6-sulfaneyl)phenyl)propanoic acid

LIFITEGRAST IMPURITY 8
Formula: C27H26Cl2N2O5S
561.48
RM-L090608
(R)-benzyl 2-(5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

Lifitegrast Impurity 80
Formula: C29H22Cl2N2O7S
613.46
RM-L090680
(Z)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)acrylic acid

Lifitegrast Impurity 81
Formula: C28H24Cl2N2O8S
619.47
RM-L090681
2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(dihydroxy(oxo)-l6-sulfaneyl)phenyl)propanoic acid

Lifitegrast Impurity 82
CAS:2832127-60-1
Formula: C15H17BrClNO4
390.66
RM-L090682
5-bromo-2-(tert-butoxycarbonyl)-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid

Lifitegrast Impurity 83
CAS:2832100-74-8
Formula: C15H17BrClNO4
390.66
RM-L090683
7-bromo-2-(tert-butoxycarbonyl)-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid

Lifitegrast Impurity 84
Formula: C11H12ClNO2
225.67
RM-L090684
methyl 7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylate

Lifitegrast Impurity 85
Formula: C11H12ClNO2
225.67
RM-L090685
methyl 5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylate

Lifitegrast Impurity 86
CAS:876108-97-3
Formula: C9H9Cl2NO
218.08
RM-L090686
5,7-dichloro-1,2,3,4-tetrahydroisoquinolin-6-ol

Lifitegrast Impurity 87
CAS:2637374-15-1
Formula: C10H8Cl2N2O3
275.09
RM-L090687
5,7-dichloro-2-nitroso-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid

Lifitegrast Impurity 88
Formula: C17H23N3O3
317.39
RM-L090688
N-((3-(dimethylamino)propyl)carbamoyl)-N-ethylbenzofuran-6-carboxamide

Lifitegrast Impurity 89
Formula: C17H23N3O3
317.39
RM-L090689
N-(3-(dimethylamino)propyl)-N-(ethylcarbamoyl)benzofuran-6-carboxamide

LIFITEGRAST IMPURITY 9
Formula: C19H17NO6S
387.41
RM-L090609
(S)-2-(Benzofuran-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 90
Formula: C19H20N2O6S2
436.5
RM-L090690
(3S,6S)-3-(3-(methylsulfonyl)benzyl)-6-(2-(methylsulfonyl)phenyl)piperazine-2,5-dione

Lifitegrast Impurity 91
CAS:58123-77-6
Formula: C7H5IO3
264.02
RM-L090691
3-Hydroxy-4-iodobenzoic acid

Lifitegrast Impurity 92
CAS:41738-72-1
Formula: C14H10O6
274.23
RM-L090692
2,2'-dihydroxy-[1,1'-biphenyl]-4,4'-dicarboxylic acid

Lifitegrast Impurity 93
CAS:82311-69-1
Formula: C9H10BrNO2
244.09
RM-L090693
(S)-2-amino-3-(3-bromophenyl)propanoic acid

Lifitegrast Impurity 96
CAS:188814-25-7
Formula: C14H18ClNO4
299.75
RM-L090696
2-((tert-Butoxycarbonyl)amino)-3-(3-chlorophenyl)propanoic acid

Lifitegrast Impurity 97
Formula: C20H24N2O7S2
468.54
RM-L090697
2-(2-amino-3-(3-(methylsulfonyl)phenyl)propanamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Impurity 98
Formula: C27H30N2O7S2
558.66
RM-L090698
benzyl 2-(2-amino-3-(3-(methylsulfonyl)phenyl)propanamido)-3-(3-(methylsulfonyl)phenyl)propanoate

Lifitegrast Impurity 99
CAS:1956318-46-9
Formula: C11H15NO4S
257.3
RM-L090699
methyl 2-amino-3-(3-(methylsulfonyl)phenyl)propanoate

Lifitegrast Nitroso Impurity 103
Formula: C20H19Cl2N3O6S
500.35
RM-L090703
(S)-2-(5,7-dichloro-2-nitroso-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

Lifitegrast Nitroso Impurity 95
Formula: C20H19Cl2N3O6S
500.35
RM-L090695
2-(5,7-dichloro-2-nitroso-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

LIFITEGRAST-D4
Formula: C29H20D4Cl2N2O7S
619.5
RM-L090661
(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido-3,3,4,4-d4)-3-(3-(methylsulfonyl)phenyl)propanoic acid

LIGUSTILIDE
CAS:4431-01-0
Formula: C12H14O2
190.24
RM-L216200
3-butylidene-4,5-dihydro-1(3H)-isobenzofuranone; 3-butylidene-4,5-dihydrophthalide

Ligustrazine Impurity 1
CAS:186534-02-1
Formula: C8H10N2O
150.18
RM-L476001
3,5,6-trimethylpyrazine-2-carbaldehyde

Ligustrazine Impurity 2
CAS:22978-83-2
Formula: C8H12N2O
152.2
RM-L476002
2,3,5,6-tetramethylpyrazine 1-oxide

LIMONENE
CAS:138-86-3
Formula: C10H16
136.24
RM-L130519
1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene

LINACLOTIDE
CAS:851199-59-2
Formula: C59H79N15O21S6
1526.73
RM-L151500
((3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-amino-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-19H-37,20-(epiminomethano)-

LINACLOTIDE IMPURITY 1
CAS:1092457-78-7
Formula: C50H70N14O19S6
1363.55
RM-L151501
(3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-amino-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-19H-37,20-(epiminomethano)-6

Linaclotide Impurity 10
Formula: C59H79N15O22S6
1542.72
RM-L151510
((3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-amino-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-3-methyl-34-oxido-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-19H-37,20-(epimino

Linaclotide Impurity 11 (Des-Tyr14)
Formula: C50H71N15O18S6
1362.57
RM-L151511
3-((3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-amino-40-(2-amino-2-oxoethyl)-15-carbamoyl-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-19H-37,20-(epiminomethano)-6,29-

Linaclotide Impurity 12 (Formaldehyde Imine Cys1)
Formula: C60H79N15O21S6
1538.74
RM-L151512
((3S,6R,9S,15R,20R,23S,26S,29R,33R,38R,41S,46aS)-41-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-3-methyl-1,4,7,10,13,22,25,28,39,42,48,49-dodecaoxotetracontahydro-19H-38,20-(epiminomethano)-30,33-met

Linaclotide Impurity 13 (Cys1 Glucose)
Formula: C65H89N15O26S6
1688.87
RM-L151513
((3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxo-32-(((3S,4R,5R)-3,4,5,6-tetrahydroxy-2-oxohexyl)ami

Linaclotide Impurity 14 (Z-Tyr-Ome)
CAS:13512-31-7
Formula: C18H19NO5
329.35
RM-L151514
methyl ((benzyloxy)carbonyl)-L-tyrosinate

Linaclotide Impurity 15 (Z-Tyr(Tbu)-Ome)
CAS:5068-29-1
Formula: C22H27NO5
385.46
RM-L151515
methyl (S)-2-(((benzyloxy)carbonyl)amino)-3-(4-(tert-butoxy)phenyl)propanoate

Linaclotide Impurity 16 (Z-Tyr(Tbu)-Oh)
CAS:5545-54-0
Formula: C21H25NO5
371.43
RM-L151516
(S)-2-(((Benzyloxy)carbonyl)amino)-3-(4-(tert-butoxy)phenyl)propanoic acid

Linaclotide Impurity 17
CAS:1155-62-0
Formula: C13H15NO6
281.26
RM-L151517
((benzyloxy)carbonyl)-L-glutamic acid

Linaclotide Impurity 18
CAS:3705-42-8
Formula: C20H21NO6
371.39
RM-L151518
(S)-5-(benzyloxy)-4-(((benzyloxy)carbonyl)amino)-5-oxopentanoic acid

Linaclotide Impurity 19
Formula: C23H27NO6
413.47
RM-L151519
5-(tert-butyl) 1-phenyl ((benzyloxy)carbonyl)-D-glutamate

LINACLOTIDE IMPURITY 2
CAS:1207977-38-5
Formula: C59H78N14O22S6
1527.71
RM-L151502
((3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-amino-26-(2-carboxyethyl)-40-(carboxymethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-19H-37,20-(epiminomethano)-6,29-

Linaclotide Impurity 20
Formula: C9H17NO4
203.24
RM-L151520
(R)-2-amino-5-(tert-butoxy)-5-oxopentanoic acid

Linaclotide Impurity 21
CAS:3373-59-9
Formula: C5H11NO3
133.15
RM-L151521
methyl L-threoninate

Linaclotide Impurity 22
CAS:57224-63-2
Formula: C13H17NO5
267.28
RM-L151522
methyl ((benzyloxy)carbonyl)-L-threoninate

Linaclotide Impurity 23
CAS:52785-41-8
Formula: C17H25NO5
323.39
RM-L151523
methyl N-((benzyloxy)carbonyl)-O-(tert-butyl)-L-threoninate

Linaclotide Impurity 24
CAS:16966-09-9
Formula: C16H23NO5
309.36
RM-L151524
N-((benzyloxy)carbonyl)-O-(tert-butyl)-L-threonine

Linaclotide Impurity 25
CAS:4378-13-6
Formula: C8H17NO3
175.23
RM-L151525
O-(tert-Butyl)-L-threonine

Linaclotide Impurity 26
CAS:57732-63-5
Formula: C18H25NO6
351.4
RM-L151526
1-(tert-butyl) 5-methyl ((benzyloxy)carbonyl)-L-glutamate

Linaclotide Impurity 27
CAS:5891-45-2
Formula: C17H23NO6
337.37
RM-L151527
(S)-4-(((benzyloxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid

Linaclotide Impurity 28
Formula: C12H22N2O5
274.32
RM-L151528
(S)-4-(3-aminopropanamido)-5-(tert-butoxy)-5-oxopentanoic acid

Linaclotide Impurity 29
Formula: C62H84N16O22S6
1597.8
RM-L151529
((3S,6S,9R,12S,18R,23R,26S,29S,32R,35R,40R,43S,48aS)-35-amino-43-(2-amino-2-oxoethyl)-29-(2-carboxyethyl)-26-(4-hydroxybenzyl)-12-((R)-1-hydroxyethyl)-3,6-dimethyl-1,4,7,10,13,16,25,28,31,34,41,44,50-tridecaoxodotetracontahydro-1H,22H-40,23

Linaclotide Impurity 3(Acylated Linaclotide)
CAS:1422389-17-0
Formula: C61H81N15O22S6
1568.76
RM-L151503
((3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-acetamido-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-19H-37,20-(epiminometha

Linaclotide Impurity 30
Formula: C50H70N14O19S6
1363.55
RM-L151530
(3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-amino-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-((S)-1-hydroxyethyl)-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-19H-37,20-(epiminomethano)-6

Linaclotide Impurity 31
CAS:13673-51-3
Formula: C19H15Cl5N2O5
528.59
RM-L151531
perchlorophenyl ((benzyloxy)carbonyl)-L-glutaminate

Linaclotide Impurity 32
CAS:13673-53-5
Formula: C20H18Cl5NO4
513.62
RM-L151532
perchlorophenyl ((benzyloxy)carbonyl)-L-isoleucinate

Linaclotide Impurity 33
CAS:13673-54-6
Formula: C24H18Cl5NO4S
593.72
RM-L151533
perchlorophenyl S-benzyl-N-((benzyloxy)carbonyl)-L-cysteinate

Linaclotide Impurity 34
CAS:23234-97-1
Formula: C18H14Cl5NO6
517.56
RM-L151534
perchlorophenyl (((4-methoxybenzyl)oxy)carbonyl)-L-serinate

Linaclotide Impurity 35
Formula: C61H81N15O22S6
1568.76
RM-L151535
((3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-acetamido-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-19H-37,20-(epiminometha

Linaclotide Impurity 36
Formula: C59H79N15O21S6
1526.73
RM-L151536
((2S,5R,8S,14R,19S,22S,25S,28R,31R,36R,39S,41aS)-31-amino-39-(2-amino-2-oxoethyl)-25-(2-carboxyethyl)-22-(4-hydroxybenzyl)-8-((R)-1-hydroxyethyl)-2-methyl-3,6,9,12,21,26,27,30,37,40,41,47-dodecaoxooctatriacontahydro-1H,18H,35H-36,19-(epimin

Linaclotide Impurity 37
Formula: C59H79N15O21S7
1558.79
RM-L151537
((3S,6R,9S,15R,21R,24S,27S,30R,33R,38R,41S,46aS)-33-amino-41-(2-amino-2-oxoethyl)-27-(2-carboxyethyl)-24-(4-hydroxybenzyl)-9-((S)-1-hydroxyethyl)-3-methyl-1,4,7,10,13,23,26,29,32,39,42,48-dodecaoxotetracontahydro-20H-38,21-(epiminomethano)-

Linaclotide Impurity 38
Formula: C61H83N15O21S6
1554.78
RM-L151538
((3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-amino-40-(2-amino-2-oxoethyl)-26-(3-ethoxy-3-oxopropyl)-23-(4-hydroxybenzyl)-9-((S)-1-hydroxyethyl)-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-19H-37,20-(epiminomet

Linaclotide Impurity 39
Formula: C61H83N15O21S6
1554.78
RM-L151539
3-((3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-amino-40-(2-amino-2-oxoethyl)-15-(((S)-1-ethoxy-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)carbamoyl)-23-(4-hydroxybenzyl)-9-((S)-1-hydroxyethyl)-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dode

LINACLOTIDE IMPURITY 4
Formula: C60H79N15O21S6
1538.74
RM-L151504
((3S,6R,15R,20R,23S,26S,29R,33R,38R,41S,46aS)-41-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-3-methyl-1,4,7,10,13,22,25,28,39,42,48,49-dodecaoxotetracontahydro-19H-38,20-(epiminomethano)-30,33-methan

Linaclotide Impurity 41
Formula: C62H85N16O22S6
1598.81
RM-L151541
((2S,5S,9S,12S,18R,23S,26S,29R,32R,37R,40S,42aS,49R)-32-amino-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-12-((R)-1-hydroxyethyl)-49-(mercaptomethyl)-2,5-dimethyl-3,6,13,16,22,27,28,31,38,41,42,48,52-tridecaoxotetracont

LINACLOTIDE IMPURITY 5
CAS:1422389-15-8(aldehyde form)
Formula: C59H76N14O22S6(aldehyde form); C59H78N14O23S6(diol form)
1525.69; 1543.71
RM-L151505
((3S,6R,9S,15R,20R,23S,26S,29R,37R,40S,45aS)-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-3-methyl-1,4,7,10,13,22,25,28,31,32,38,41,47-tridecaoxotetracontahydro-19H-37,20-(epiminomethano)-6,29-(met

Linaclotide Impurity 6 (Glucose Cys1)
Formula: C65H89N15O27S6
1704.87
RM-L151506
((3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxo-32-((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanamido)

LINACLOTIDE IMPURITY 7
CAS:1264468-60-1
Formula: C60H79N15O21S6
1538.74
RM-L151507
((3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-3-methyl-32-(methyleneamino)-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-19H-37,20-(epimi

Linaclotide Impurity 8
Formula: C118H160N30O42S12
3055.47
RM-L151508
(2S,2'S)-2,2'-(((3S,3'S,6R,6'R,9S,9'S,15R,15'R,20R,20'R,23S,23'S,26S,26'S,29R,29'R,32R,32'R,37R,37'R,40S,40'S,45aS,45a'S)-6,6'-(disulfanediylbis(methylene))bis(32-amino-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-((R)

Linaclotide Impurity A (Methyl L-Tyrosinate)
CAS:1080-06-4
Formula: C10H13NO3
195.22
RG-D201802
(S)-methyl 2-amino-3-(4-hydroxyphenyl)propanoate

LINACLOTIDE-D4
Formula: C59H75D4N15O21S6
1530.75
RM-L151509
((3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-amino-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-3-(methyl-d3)-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-19H-37,20-(epiminometh

LINAGLIPTIN
CAS:668270-12-0
Formula: C25H28N8O2
472.54
RM-L140700
(R)-8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN ACETAMIDE
CAS:1803079-49-3
Formula: C27H30N8O3
514.58
RM-L140733
(R)-N-(1-(7-(But-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)acetamide

Linagliptin Dimer Impurity 206
Formula: C51H56N16O4
957.12
RM-L140882
8-((S)-3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-1-((4-(2-(((S)-1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)amino)ethyl)quinazolin-2-yl)methyl)-3-methyl-3,7-dihy

LINAGLIPTIN IMPURITY 1
CAS:13535-91-6
Formula: C10H10N2O
174.2
RM-L140727
(4-methylquinazolin-2-yl)methanol

Linagliptin Impurity 101
Formula: C18H17N3O
291.35
RM-L140775
1-(2-(((4-methylquinazolin-2-yl)methyl)amino)phenyl)ethanone

Linagliptin Impurity 102
Formula: C26H30N8O2
486.57
RM-L140776
8-((R)-3-aminopiperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-7-(penta-2,3-dien-1-yl)-1H-purine-2,6(3H,7H)-dione

Linagliptin Impurity 103
CAS:2074688-84-7
Formula: C22H23N7O3
433.46
RM-L140777
7-(but-2-yn-1-yl)-8-((2-hydroxyethyl)amino)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

Linagliptin Impurity 104
CAS:2074688-81-4
Formula: C33H32N8O5
620.66
RM-L140778
(R)-2-((1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamoyl)benzoic acid

Linagliptin Impurity 105
CAS:886588-63-2
Formula: C33H30N8O4
602.64
RM-L140779
(R)-7-(but-2-yn-1-yl)-8-(3-(1,3-dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY 106
CAS:1955514-80-3
Formula: C26H29N9O3
515.57
RM-L140780
1-(1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)urea

Linagliptin Impurity 107
CAS:551-93-9
Formula: C8H9NO
135.16
RM-L140781
1-(2-aminophenyl)ethanone

Linagliptin Impurity 108
CAS:216854-23-8
Formula: C10H20N2O2
200.28
RM-L140782
(S)-tert-butyl piperidin-3-ylcarbamate

Linagliptin Impurity 109
CAS:188111-79-7
Formula: C10H20N2O2
200.28
RM-L140783
(R)-tert-Butyl 3-aminopiperidine-1-carboxylate

Linagliptin impurity 110
Formula: C20H18N6O3
390.4
RM-L140784
7-(but-2-yn-1-yl)-8-hydroxy-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

Linagliptin impurity 111
Formula: C16H15BrN6O2
403.23
RM-L140785
8-bromo-3-methyl-7-((4-methyl-4a,8a-dihydroquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

Linagliptin impurity 112
Formula: C25H27N7O3
473.53
RM-L140786
7-(but-2-yn-1-yl)-8-(3-hydroxypiperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

Linagliptin impurity 113
Formula: C20H18Br2N6O2
534.2
RM-L140787
(Z)-8-bromo-7-(3-bromobut-2-en-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY 115
CAS:2137744-33-1
Formula: C26H28N8O3
500.55
RM-L140789
N-(1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)formamide

Linagliptin Impurity 116
Formula: C31H38N8O7
634.69
RM-L140790
methyl)-8-((3R)-3-(((3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)amino)piperidin-1-yl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 117
Formula: C30H36N8O4
572.67
RM-L140791
tert-butyl (R)-3-((7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)amino)piperidine-1-carboxylate

Linagliptin Impurity 118
Formula: C30H37BrN8O4
653.58
RM-L140792
tert-butyl (R)-(1-(7-(3-bromobut-2-en-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate

Linagliptin Impurity 119
Formula: C30H26N8O3
546.59
RM-L140793
7-(but-2-yn-1-yl)-3-methyl-8-((4-methylquinazolin-2-yl)methoxy)-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 120
Formula: C25H28N8O2*2
472.55*2
RM-L140794
8-((R)-3-aminopiperidin-1-yl)-7-((R)-buta-1,2-dien-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione--8-((R)-3-aminopiperidin-1-yl)-7-((S)-buta-1,2-dien-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7

Linagliptin Impurity 121
Formula: C20H17BrN6O2
453.3
RM-L140795
8-Bromo-7-(but-2-yn-1-yl)-3-methyl-6-((4-methylquinazolin-2-yl)methoxy)-3,7-dihydro-2H-purin-2-one

Linagliptin Impurity 123
Formula: C23H27ClO8
466.91
RM-L140797
(3S,4S,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-3,4,5-trihydroxy-2-(hydroxymethyl)-6-methoxytetrahydro-2H-pyran-2-carbaldehyde

Linagliptin Impurity 124
CAS:1528636-45-4
Formula: C22H25ClO6
420.89
RM-L140798
(2S,3R,4S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)-2-methoxy-3,4-dihydro-2H-pyran-3,4-diol

Linagliptin Impurity 125
Formula: C44H50Cl2O14
873.77
RM-L140799
(2R,3S,4S,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-2-(((3S,4S,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-3,4,5-trihydroxy-6-methoxytetrahydro-2H-pyran-2-yl)(hydroxy)methyl)-3,4,5-trihydroxy-6-methoxytetrahydro-2H-pyran-2-carbaldehyde

Linagliptin Impurity 126
CAS:1528636-47-6
Formula: C22H25ClO8
452.88
RM-L140802
(2S,3S,4S,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-3,4,5-trihydroxy-6-methoxytetrahydro-2H-pyran-2-carboxylic acid

Linagliptin Impurity 127
CAS:1528636-36-3
Formula: C31H51ClO10SSi3
735.5
RM-L140803
((2R,3R,4S,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-methoxy-3,4,5-tris((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)methyl hydrogen sulfate

Linagliptin Impurity 128
Formula: C31H40N10O2
584.73
RM-L140804
7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(3-(((piperidin-3-ylamino)methyl)amino)piperidin-1-yl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 129
CAS:1446263-39-3
Formula: C25H29BrN8O2
553.47
RM-L140805
(R,E)-8-(3-aminopiperidin-1-yl)-7-(3-bromobut-2-en-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 130
Formula: C52H58N16O4
971.14
RM-L140806
8-((R)-3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-1-((4-((2S)-2-((1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)amino)propyl)quinazolin-2-yl)methyl)-3-methyl-3,7-di

Linagliptin Impurity 131
Formula: C27H34N8O3
518.62
RM-L140807
(R,E)-8-(3-aminopiperidin-1-yl)-1-((4-ethylquinazolin-2-yl)methyl)-7-(4-hydroxy-3-methylbut-2-en-1-yl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 132
CAS:1620278-39-8
Formula: C25H27N7O3
473.54
RM-L140808
(S)-7-(but-2-yn-1-yl)-8-(3-hydroxypiperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 133
CAS:764-01-2
Formula: C4H6O
70.09
RM-L140809
But-2-yn-1-ol

Linagliptin Impurity 134
CAS:586408-08-4
Formula: C10H10N4O2
218.22
RM-L140810
7-(but-2-yn-1-yl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 135 (Dimer)
Formula: C52H59N17O4
986.16
RM-L140811
1-((4-((R)-2-(((3R,5R)-5-amino-1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)amino)propyl)quinazolin-2-yl)methyl)-8-((R)-3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-

Linagliptin Impurity 136
CAS:2463617-49-2
Formula: C51H56N16O4
957.12
RM-L140812
8-((R)-3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-1-((4-(2-(((R)-1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)amino)ethyl)quinazolin-2-yl)methyl)-3-methyl-3,7-dihy

Linagliptin Impurity 137
Formula: C21H20N6O3
404.43
RM-L140813
7-(but-2-yn-1-yl)-8-methoxy-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 138
Formula: C33H30N8O4
602.66
RM-L140814
(S)-7-(but-2-yn-1-yl)-8-(3-(1,3-dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 139
Formula: C23H22N6O4
446.47
RM-L140815
(R)-7-(but-2-yn-1-yl)-8-(3-(1,3-dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 140
Formula: C23H22N4O2
386.46
RM-L140816
(R)-2-(1-((4-methylquinazolin-2-yl)methyl)piperidin-3-yl)isoindoline-1,3-dione

Linagliptin Impurity 141
Formula: C46H44N10O6
832.92
RM-L140817
N-((R)-1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)-2-((R)-3-(1,3-dioxoisoindolin-2-yl)piperidine-1-carbonyl)benzamide

Linagliptin Impurity 142
Formula: C39H34N10O4
706.77
RM-L140818
(R)-8-(3-(1,3-dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-1,7-bis((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 143
Formula: C33H31BrN8O4
683.57
RM-L140819
(R,Z)-7-(3-bromobut-2-en-1-yl)-8-(3-(1,3-dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 144
Formula: C35H37N9O5
663.74
RM-L140820
(R)-N1-(1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)-N2-(2-hydroxyethyl)phthalamide

Linagliptin Impurity 145
Formula: C31H38N8O7
634.69
RM-L140821
7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-8-((3R)-3-((3,4,5,6-tetrahydroxy-2-oxohexyl)amino)piperidin-1-yl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 146
Formula: C25H28N8O3
488.55
RM-L140822
(R)-7-(But-2-yn-1-yl)-8-(3-(hydroxyamino)piperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 147
Formula: C10H10N4O3
234.22
RM-L140823
7-(but-2-yn-1-yl)-8-hydroxy-3-methyl-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 148
CAS:2446799-71-7
Formula: C20H17BrN6O2
453.3
RM-L140824
8-Bromo-7-(but-2-yn-1-yl)-3-methyl-2-((4-methylquinazolin-2-yl)methoxy)-3,7-dihydro-6H-purin-6-one

Linagliptin Impurity 149
CAS:2468656-63-3
Formula: C21H21N7O2
403.45
RM-L140825
7-(but-2-yn-1-yl)-3-methyl-8-(methylamino)-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 150
Formula: C21H29N5O3
399.5
RM-L140826
tert-butyl (R)-(1-(((4-methylquinazolin-2-yl)methyl)carbamoyl)piperidin-3-yl)carbamate

Linagliptin Impurity 151
Formula: C25H30N8O2
474.57
RM-L140827
8-((S)-3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,4,5,7-tetrahydro-1H-purine-2,6-dione

Linagliptin Impurity 152
Formula: C24H28N8O2
460.54
RM-L140828
(R)-8-(3-aminopiperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-7-(prop-1-en-1-yl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 153
Formula: C52H58N16O4
971.14
RM-L140829
8-((R)-3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-1-((4-(2-((1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)amino)propyl)quinazolin-2-yl)methyl)-3-methyl-3,7-dihydro

Linagliptin Impurity 154
Formula: C20H17BrN8O4
513.31
RM-L140830
Linagliptin Impurity 154

Linagliptin Impurity 155
Formula: C50H58N16O4
947.12
RM-L140831
8-((R)-3-aminopiperidin-1-yl)-1-((4-((2-((8-((R)-3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,4,5,6,7-hexahydro-1H-purin-1-yl)methyl)quinazolin-4-yl)methyl)-4-methyl-1,4-dihydroquinazolin-2-yl)methyl)-7-(but-2-yn-1-yl)-3-

Linagliptin Impurity 156
Formula: C25H29N7O4
491.55
RM-L140832
N-(2-acetylphenyl)-2-(8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)acetamide

Linagliptin Impurity 157
Formula: C14H12N4O3
284.28
RM-L140833
1-methyl-3-((4-methylquinazolin-2-yl)methyl)imidazolidine-2,4,5-trione

Linagliptin Impurity 158
Formula: C25H29ClN8O2
509.01
RM-L140834
(R,Z)-8-(3-aminopiperidin-1-yl)-7-(3-chlorobut-2-en-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 159
CAS:2138805-26-0
Formula: C25H29ClN8O2
509.01
RM-L140835
8-(3-aminopiperidin-1-yl)-7-(3-chlorobut-2-en-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 160
Formula: C10H9BrN4O2
297.11
RM-L140836
8-bromo-1-(but-2-yn-1-yl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 161
CAS:6140-12-1
Formula: C10H9Cl2NO2
246.09
RM-L140837
N-(2-acetylphenyl)-2,2-dichloroacetamide

Linagliptin Impurity 162
Formula: C25H29ClN8O2
509.01
RM-L140838
(R)-8-(3-aminopiperidin-1-yl)-7-(3-chlorobut-2-en-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 163
Formula: C16H14N6O2
322.33
RM-L140839
3-methyl-7-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 164
Formula: C52H57N15O4
956.13
RM-L140840
7-(but-2-yn-1-yl)-8-((3R)-3-(((((1R)-3-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)cyclohexyl)amino)methyl)amino)piperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7

Linagliptin Impurity 165
Formula: C30H36N8O4
572.67
RM-L140841
tert-butyl (R)-(1-(1-(but-2-yn-1-yl)-3-methyl-7-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate

Linagliptin Impurity 166
Formula: C10H11BrN4O3
315.13
RM-L140842
8-bromo-3-methyl-7-(3-oxobutyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 167
Formula: C20H17BrN6O2
453.3
RM-L140843
8-bromo-1-(but-2-yn-1-yl)-3-methyl-7-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 168
Formula: C20H19BrN6O3
471.32
RM-L140844
8-bromo-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-7-(3-oxobutyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 169
Formula: C45H44N12O2
784.93
RM-L140845
(R)-8-(3-(bis((4-methylquinazolin-2-yl)methyl)amino)piperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 170
Formula: C35H36N10O2
628.74
RM-L140846
(R)-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(3-(((4-methylquinazolin-2-yl)methyl)amino)piperidin-1-yl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 171
CAS:1803079-48-2
Formula: C22H22N6O3
418.46
RM-L140847
7-(but-2-yn-1-yl)-8-ethoxy-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 172
Formula: C30H38N8O5
590.69
RM-L140848
tert-butyl (R)-(1-(3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-7-(3-oxobutyl)-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate

Linagliptin Impurity 173
Formula: C26H22N8O2
478.52
RM-L140849
3-methyl-1,7-bis((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 174
Formula: C30H36N8O4
572.67
RM-L140850
tert-butyl 4-((7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)amino)piperidine-1-carboxylate

Linagliptin Impurity 175
Formula: C52H58N16O4
971.14
RM-L140851
8-((R)-3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-1-((4-((R)-2-(((R)-1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)amino)propyl)quinazolin-2-yl)methyl)-3-methyl-3,7

Linagliptin Impurity 176
CAS:40104-07-2
Formula: CH3ClO3S
130.54
RM-L140852
chloromethanesulfonic acid

Linagliptin Impurity 177
Formula: C10H11ClN2O
210.66
RM-L140853
N-(2-acetylphenyl)-2-chloroacetimidamide

Linagliptin Impurity 179
CAS:2803372-57-6
Formula: C30H37BrN8O4
653.58
RM-L140855
tert-butyl (R,Z)-(1-(7-(3-bromobut-2-en-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate

Linagliptin Impurity 180
Formula: C26H29N7O2
471.57
RM-L140856
(R)-8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylene-3,4-dihydroquinolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 183
Formula: C27H32N8O2
500.61
RM-L140859
(R)-7-(but-2-yn-1-yl)-8-(3-(dimethylamino)piperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 184
Formula: C26H30N8O2
486.58
RM-L140860
(R)-7-(but-2-yn-1-yl)-3-methyl-8-(3-(methylamino)piperidin-1-yl)-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 185
Formula: C24H26N8O2
458.53
RM-L140861
(R)-8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 186
Formula: C26H32N8O3
504.6
RM-L140862
(R,E)-8-(3-aminopiperidin-1-yl)-7-(4-hydroxy-3-methylbut-2-en-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 187
Formula: C19H26N4O2
342.44
RM-L140863
tert-butyl (R)-(1-(quinazolin-2-ylmethyl)piperidin-3-yl)carbamate

Linagliptin Impurity 188
Formula: C31H38N8O7
634.69
RM-L140864
7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(3-((3,4,5,6-tetrahydroxy-2-oxohexyl)amino)piperidin-1-yl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 189
Formula: C31H40N10O2
584.73
RM-L140865
7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-8-((R)-3-(((((R)-piperidin-3-yl)amino)methyl)amino)piperidin-1-yl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 191
Formula: C34H34N8O4
618.7
RM-L140867
7-((E)-but-2-en-1-yl)-8-((3R)-3-(1,3-dioxoisoindolin-2-yl)-4-methylpiperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 193
Formula: C29H32N8O7
604.62
RM-L140869
(2R,3R)-4-(((R)-1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)amino)-2,3-dihydroxy-4-oxobutanoic acid

Linagliptin Impurity 194
Formula: C20H19BrN6O2
455.32
RM-L140870
8-Bromo-7-(but-2-yn-1-yl)-3-methyl-6-((4-methylquinazolin-2-yl)methoxy)-1,3,6,7-tetrahydro-2H-purin-2-one

Linagliptin Impurity 195
Formula: C19H22N6O
350.43
RM-L140871
3-(but-2-yn-1-yl)-5-(methylamino)-N-((4-methylquinazolin-2-yl)methyl)-2,3-dihydro-1H-imidazole-4-carboxamide

Linagliptin Impurity 196
Formula: C10H9Br3N4O2
456.92
RM-L140872
(E)-8-bromo-7-(2,3-dibromobut-2-en-1-yl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 197
Formula: C22H25ClO7
436.89
RM-L140873
(1S,2S,3S,4R,5R)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol

Linagliptin Impurity 198
Formula: C22H25ClO7
436.89
RM-L140874
(1S,2R,3S,4S,5S)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol

Linagliptin Impurity 199
Formula: C21H23ClO6
406.86
RM-L140875
(1S,2S,3S,4R,5S)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol

LINAGLIPTIN IMPURITY 2
Formula: C28H32N8O4
544.6
RM-L140728
(S)-tert-butyl (1-(7-ethynyl-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate

Linagliptin Impurity 200
Formula: C52H58N16O4
971.14
RM-L140876
8-((R)-3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-1-((4-((S)-2-(((R)-1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)amino)propyl)quinazolin-2-yl)methyl)-3-methyl-3,7

Linagliptin Impurity 201
Formula: C25H28N8O2
472.55
RM-L140877
8-((R)-3-aminopiperidin-1-yl)-7-((R)-buta-1,2-dien-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 202
Formula: C26H28N8O3
500.56
RM-L140878
(S)-N-(1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)formamide

Linagliptin Impurity 203
Formula: C25H29BrN8O2
553.47
RM-L140879
(S)-8-(3-aminopiperidin-1-yl)-7-(3-bromobut-2-en-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 204
Formula: C52H58N16O4
971.14
RM-L140880
8-((R)-3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-1-((4-(2-(((R)-1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)amino)propyl)quinazolin-2-yl)methyl)-3-methyl-3,7-dih

Linagliptin Impurity 205
Formula: C12H10BrN5O2
336.15
RM-L140881
2-(8-bromo-7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)acetonitrile

Linagliptin Impurity 208
Formula: C25H32N8O2
476.59
RM-L140884
(R)-8-(3-aminopiperidin-1-yl)-7-butyl-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Impurity 210
CAS:2408731-72-4
Formula: C20H28N4O2
356.47
RM-L140886
tert-butyl (4-((3-amino-2,6-dimethylpyridin-4-yl)amino)phenethyl)carbamate

Linagliptin Impurity 211
Formula: C25H28N8O3
488.55
RM-L140887
3-amino-1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidine 1-oxide

LINAGLIPTIN IMPURITY 3
Formula: C15H20N4
256.35
RM-L140729
(R)-1-((4-methylquinazolin-2-yl)methyl)piperidin-3-amine

LINAGLIPTIN IMPURITY 36
Formula: C10H6D3BrN4O2
300.13
RM-L140734
Linagliptin Impurity

LINAGLIPTIN IMPURITY 37
Formula: C26H29N9O3
515.57
RM-L140735
(R)-1-(1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)urea

LINAGLIPTIN IMPURITY 38
Formula: C10H10Br2N4O2
378.02
RM-L140736
(Z)-8-bromo-7-(3-bromobut-2-en-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY 39
CAS:88203-04-7
Formula: C10H10N2O
174.2
RM-L140737
2-((2-acetylphenyl)amino)acetonitrile

LINAGLIPTIN IMPURITY 4
Formula: C18H14N6O3
362.34
RM-L140730
7-ethynyl-8-hydroxy-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY 40
Formula: C50H56N16O4
945.08
RM-L140738
8-((R)-3-aminopiperidin-1-yl)-7-(3-(((R)-1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)amino)but-2-en-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine

LINAGLIPTIN IMPURITY 42
CAS:2803369-89-1
Formula: C25H27N7O3
473.53
RM-L140739
(R)-7-(but-2-yn-1-yl)-8-(3-hydroxypiperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY 5
Formula: C24H24N8O3
472.5
RM-L140731
(R)-N-(1-(7-ethynyl-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)formamide

LINAGLIPTIN IMPURITY 6
Formula: C25H23F3N8O3
540.5
RM-L140732
(R)-N-(1-(7-ethynyl-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)-2,2,2-trifluoroacetamide

LINAGLIPTIN IMPURITY 60
CAS:2428491-17-0
Formula: C16H13BrN6O2
401.22
RM-L140740
8-bromo-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY 61
CAS:2512206-89-0
Formula: C10H9BrN4O2
297.11
RM-L140741
8-bromo-9-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,9H)-dione

LINAGLIPTIN IMPURITY 62
CAS:2138392-83-1
Formula: C26H21BrN8O2
557.4
RM-L140742
8-bromo-3-methyl-1,7-bis((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY 63
Formula: C27H30N8O3
514.58
RM-L140743
(S)-N-(1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)acetamide

Linagliptin Impurity 64(Linagliptin Diene Impurity)
CAS:2463617-43-6
Formula: C25H28N8O2
472.54
RM-L140744
8-((R)-3-aminopiperidin-1-yl)-7-(buta-1,2-dien-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY 65
CAS:2489212-72-6
Formula: C51H56N16O4
957.12
RM-L140745
8,8'-((3R,3'R)-3,3'-(methylenebis(azanediyl))bis(piperidine-3,1-diyl))bis(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione)

LINAGLIPTIN IMPURITY 66
CAS:668273-75-4
Formula: C30H36N8O4
572.66
RM-L140746
(R)-tert-butyl (1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate

Linagliptin Impurity 67
CAS:109113-72-6
Formula: C10H9ClN2
192.64
RM-L140747
2-(Chloromethyl)-4-methylquinazoline

LINAGLIPTIN IMPURITY 68
CAS:1643364-41-3
Formula: C54H62N16O4
999.17
RM-L140748
(R)-1,1'-((4,4'-(2-propylpropane-1,3-diyl)bis(quinazoline-4,2-diyl))bis(methylene))bis(8-((R)-3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione)

LINAGLIPTIN IMPURITY 69
Formula: C25H25D3N8O2
475.56
RM-L140749
Linagliptin Impurity 69

LINAGLIPTIN IMPURITY 70
Formula: C45H44N14O4
844.92
RM-L140750
(R)-7-(but-2-yn-1-yl)-8-(3-((7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)amino)piperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY 71
Formula: C20H17ClN6O2
408.84
RM-L140751
7-(but-2-yn-1-yl)-8-chloro-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

Linagliptin Impurity 72
Formula: C10H9ClN4O2
252.66
RM-L140752
7-(but-2-yn-1-yl)-8-chloro-3-methyl-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY 73
CAS:666816-98-4
Formula: C10H9BrN4O2
297.11
RM-L140753
8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY 74
Formula: C30H36N8O4
572.66
RM-L140754
tert-butyl (1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate

LINAGLIPTIN IMPURITY 75
CAS:93703-24-3
Formula: C6H5BrN4O2
245.03
RM-L140755
8-bromo-3-methyl-1H-purine-2,6(3H,9H)-dione

LINAGLIPTIN IMPURITY 76
Formula: C25H30N8O3
490.56
RM-L140756
(R)-8-(3-aminopiperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-7-(3-oxobutyl)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY 77
Formula: C25H28N8O3
488.54
RM-L140757
(R)-8-(3-aminopiperidin-1-yl)-7-(4-hydroxybut-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY 78
Formula: C30H36N8O4
572.66
RM-L140758
(R)-tert-butyl (1-(7-(but-2-yn-1-yl)-3-methyl-6-((4-methylquinazolin-2-yl)methoxy)-2-oxo-3,7-dihydro-2H-purin-8-yl)piperidin-3-yl)carbamate

LINAGLIPTIN IMPURITY 79
CAS:2514724-20-8
Formula: C25H28N8O2
472.54
RM-L140759
(R)-8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-6-((4-methylquinazolin-2-yl)methoxy)-3,7-dihydro-2H-purin-2-one

Linagliptin Impurity 80
Formula: C30H36N8O4
572.66
RM-L140760
(R)-tert-butyl (1-(7-(but-2-yn-1-yl)-3-methyl-2-((4-methylquinazolin-2-yl)methoxy)-6-oxo-6,7-dihydro-3H-purin-8-yl)piperidin-3-yl)carbamate

LINAGLIPTIN IMPURITY 81
CAS:2446799-72-8
Formula: C25H28N8O2
472.54
RM-L140761
(R)-8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-2-((4-methylquinazolin-2-yl)methoxy)-3H-purin-6(7H)-one

LINAGLIPTIN IMPURITY 82
Formula: C50H62N14O8
987.12
RM-L140762
di-tert-butyl ((3R,3'R)-1,1'-(1,1'-(quinazoline-2,4-diylbis(methylene))bis(7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purine-8,1-diyl))bis(piperidine-3,1-diyl))dicarbamate

LINAGLIPTIN IMPURITY 83
Formula: C26H32N8O4
520.58
RM-L140763
(R)-tert-butyl (1-(3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate

LINAGLIPTIN IMPURITY 84
Formula: C21H24N8O2
420.47
RM-L140764
(R)-8-(3-aminopiperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY 85
Formula: C36H40N10O4
676.77
RM-L140765
(R)-tert-butyl (1-(3-methyl-1,7-bis((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate

LINAGLIPTIN IMPURITY 86
Formula: C5H12N2 2HCl
100.16 72.92
RM-L140766
Piperidin-3-amine dihydrochloride

LINAGLIPTIN IMPURITY 87
CAS:309956-78-3
Formula: C10H20N2O2
200.28
RM-L140767
(R)-tert-Butyl piperidin-3-ylcarbamate

LINAGLIPTIN IMPURITY 89
Formula: C40H46N14O4
786.88
RM-L140769
(R)-1,1'-(quinazoline-2,4-diylbis(methylene))bis(8-((R)-3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione)

Linagliptin Impurity 90
Formula: C6H6N4O2
166.14
RM-L140770
3-methyl-1H-purine-2,6(3H,9H)-dione

LINAGLIPTIN IMPURITY 91
Formula: C31H32N10O2
576.65
RM-L140771
(R)-8-(3-aminopiperidin-1-yl)-3-methyl-1,7-bis((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY 92
Formula: C25H28N8O2
472.54
RM-L140772
(R)-8-(3-Aminopiperidin-1-yl)-1-(but-2-yn-1-yl)-3-methyl-7-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY 93
Formula: C9H16N2
152.24
RM-L140773
(R)-1-(but-2-yn-1-yl)piperidin-3-amine

LINAGLIPTIN IMPURITY 94
CAS:853029-57-9
Formula: C20H17BrN6O2
453.29
RM-L140774
8-bromo-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY A
CAS:2518331-40-1
Formula: C24H32N6O4
468.55
RM-L140701
(R)-tert-butyl (1-(1,7-di(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate

Linagliptin Impurity A1
CAS:2514949-81-4
Formula: C20H28N4O2
356.46
RM-L140725
(R)-tert-butyl (1-((4-methylquinazolin-2-yl)methyl)piperidin-3-yl)carbamate;tert-butyl (R)-(1-((4-methylquinazolin-2-yl)methyl)piperidin-3-yl)carbamate

LINAGLIPTIN IMPURITY B
Formula: C16H13BrN6O2
401.22
RM-L140702
8-bromo-3-methyl-7-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY C
Formula: C26H32N8O4
520.58
RM-L140703
(R)-tert-butyl (1-(3-methyl-7-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate

LINAGLIPTIN IMPURITY D
Formula: C21H24N8O2
420.47
RM-L140704
(R)-8-(3-aminopiperidin-1-yl)-3-methyl-7-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY E
CAS:1446263-38-2
Formula: C25H28N8O2
472.54
RM-L140705
(R)-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY F
CAS:2279114-31-5
Formula: C20H18BrN5O4
472.29
RM-L140706
N-(2-acetylphenyl)-2-(8-bromo-7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)acetamide

LINAGLIPTIN IMPURITY G
CAS:668270-11-9
Formula: C25H28N8O2
472.55
RM-L140707
(S)-8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY H
CAS:2279114-27-9
Formula: C30H37N7O6
591.66
RM-L140708
(R)-tert-butyl (1-(1-(2-((2-acetylphenyl)amino)-2-oxoethyl)-7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate

LINAGLIPTIN IMPURITY I
Formula: C14H24N2O2
252.35
RM-L140709
(R)-tert-butyl (1-(but-2-yn-1-yl)piperidin-3-yl)carbamate

LINAGLIPTIN IMPURITY J
CAS:2436762-89-7
Formula: C14H13BrN4O2
349.18
RM-L140710
8-bromo-1,7-di(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY K
CAS:2749409-37-6
Formula: C19H24N6O2
368.43
RM-L140711
(R)-8-(3-aminopiperidin-1-yl)-1,7-di(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY L
Formula: C20H28N6O4
416.47
RM-L140712
(R)-tert-butyl (1-(7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate

LINAGLIPTIN IMPURITY M
CAS:1791405-13-4
Formula: C15H20N6O2
316.36
RM-L140713
(R)-8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY N
CAS:2416949-69-2
Formula: C25H29N7O4
491.54
RM-L140714
(R)-N-(2-acetylphenyl)-2-(8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)acetamide

LINAGLIPTIN IMPURITY O
CAS:6140-11-0
Formula: C10H10ClNO2
211.64
RM-L140715
N-(2-acetylphenyl)-2-chloroacetamide

LINAGLIPTIN IMPURITY P
CAS:668273-74-3
Formula: C30H36N8O4
572.66
RM-L140716
(S)-tert-butyl (1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate

LINAGLIPTIN IMPURITY Q
CAS:1673546-62-7
Formula: C27H27F3N8O3
568.55
RM-L140717
(R)-N-(1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)-2,2,2-trifluoroacetamide

LINAGLIPTIN IMPURITY R
CAS:1646355-34-1
Formula: C22H23N7O2
417.46
RM-L140718
7-(but-2-yn-1-yl)-8-(dimethylamino)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY S
CAS:1638744-06-5
Formula: C25H29BrN8O2
553.45
RM-L140719
(R,Z)-8-(3-aminopiperidin-1-yl)-7-(3-bromobut-2-en-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

LINAGLIPTIN IMPURITY T(LINAGLIPTIN METHYLDIMER)
CAS:1418133-47-7
Formula: C50H56N16O4
945.08
RM-L140720
8-((R)-3-aminopiperidin-1-yl)-1-((4-((2-((8-((R)-3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)methyl)-4-methyl-1,4-dihydroquinazolin-4-yl)methyl)quinazolin-2-yl)methyl)-7-(but-2-yn-1-yl)-3-met

LINAGLIPTIN IMPURITY W
CAS:2074688-82-5
Formula: C58H58N16O6
1075.18
RM-L140721
N1,N2-bis((R)-1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)phthalamide

LINAGLIPTIN IMPURITY X
CAS:2443735-53-1
Formula: C38H42N10O4
702.82
RM-L140722
2-((R)-3-aminopiperidine-1-carbonyl)-N-((R)-1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)benzamide

LINAGLIPTIN IMPURITY Y
CAS:1911621-52-7
Formula: C20H18N6O2
374.4
RM-L140723
7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

Linagliptin Impurity Z
CAS:3037659-49-4
Formula: C26H28N8O3
500.55
RM-L140724
(R)-N-(1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)formamide

Linagliptin Impurity Z2
Formula: C25H28N8O2
472.55
RM-L140726
(S)-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-1H-purine-2,6(3H,7H)-dione

Linagliptin nitroso Impurity 181
Formula: C25H27N9O3
501.55
RM-L140857
(R)-N-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-N-(piperidin-3-yl)nitrous amide

Linagliptin nitroso Impurity 182
Formula: C25H26N10O4
530.55
RM-L140858
(R)-N-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-N-(1-nitrosopiperidin-3-yl)nitrous amide

Linagliptin Nitroso Impurity 190
Formula: C24H25N9O3
487.52
RM-L140866
(R)-8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-1-((4-methylquinazolin-2-yl)methyl)-3-nitroso-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Nitroso Impurity 192
Formula: C25H27N9O3
501.55
RM-L140868
(R)-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-8-((1-nitrosopiperidin-3-yl)amino)-3,7-dihydro-1H-purine-2,6-dione

Linagliptin Nitroso Impurity 207
Formula: C25H27N9O3
501.55
RM-L140883
(R)-N-(1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)nitrous amide

Linagliptin Nitroso Impurity 209
Formula: C21H20N8O3
432.44
RM-L140885
N-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-N-methylnitrous amide

LINAGLIPTIN-13C-D3
CAS:1398044-43-3
Formula: C2413CH25D3N8O2
476.55
RM-L140768
Linagliptin-13C-d3

LINAGLIPTIN-D4
CAS:2140263-92-7
Formula: C25H24D4N8O2
476.57
RM-L140788
Linagliptin-d4

LINAMARIN
CAS:554-35-8
Formula: C10H17NO6
247.25
RM-L482000
2-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)propanenitrile

Linaprazan Impurity 1
Formula: C52H64N8O10
961.13
RM-L752001
5-(2-(8-((2,6-dimethylbenzyl)amino)-5-((5-(2-(8-((2,6-dimethylbenzyl)amino)-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxamido)ethoxy)-5-oxopentanoyl)oxy)-2,3-dimethyl-1,5-dihydroimidazo[1,2-a]pyridine-6-carboxamido)ethoxy)-5-oxopentanoic aci

LINCOMYCIN B
CAS:2520-24-3
Formula: C17H32N2O6S
392.51
RM-L140328
(2S,4R)-4-ethyl-N-((1R,2R)-2-hydroxy-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-1-methylpyrrolidine-2-carboxamide

Lincomycin Hydrochloride EP Impurity A
Formula: C18H34N2O6S
406.54
RM-L140327
(2R,4R)-N-((1R,2R)-2-hydroxy-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-1-methyl-4-propylpyrrolidine-2-carboxamide

LINCOMYCIN HYDROCHLORIDE EP IMPURITY B
CAS:37744-65-3
Formula: C18H32N2O6S
404.52
RM-L140302
(S)-N-((1R,2R)-2-hydroxy-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-1-methyl-4-propylidenepyrrolidine-2-carboxamide

LINCOMYCIN HYDROCHLORIDE EP IMPURITY C
CAS:14600-41-0
Formula: C17H32N2O6S*HCl
392.52 36.46
RM-L140303
(2S,4R)-N-((1R,2R)-2-hydroxy-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-4-propylpyrrolidine-2-carboxamide hydrochloride

LINCOMYCIN HYDROCHLORIDE EP IMPURITY E
CAS:13380-36-4
Formula: C9H17NO2
171.24
RM-L140305
(2S,4R)-1-methyl-4-propylpyrrolidine-2-carboxylic acid

LINCOMYCIN HYDROCHLORIDE EP IMPURITY F
CAS:14810-93-6
Formula: C9H19NO5S
253.32
RM-L140306
(2R,3R,4S,5R,6R)-2-((1R,2R)-1-amino-2-hydroxypropyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol

Lincomycin Hydrochloride Impurity 30
Formula: C18H33N2O8PS
468.5
RM-L140330
(2S,4R)-N-((1R,2R)-1-((2R,3aS,4R,6R,7R,7aR)-2,7-dihydroxy-6-(methylthio)-2-oxidotetrahydro-3aH-[1,3,2]dioxaphospholo[4,5-c]pyran-4-yl)-2-hydroxypropyl)-1-methyl-4-propylpyrrolidine-2-carboxamide

Lincomycin Hydrochloride Impurity 31
Formula: C18H32N2O5S
388.52
RM-L140331
(2S,4R)-1-methyl-4-propyl-N-((E)-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)prop-1-en-1-yl)pyrrolidine-2-carboxamide

Lincomycin Hydrochloride Impurity 33
CAS:198080-68-1
Formula: C18H34N2O8S
438.54
RM-L140333
(2S,4R)-N-((1R,2R)-2-hydroxy-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfonyl)tetrahydro-2H-pyran-2-yl)propyl)-1-methyl-4-propylpyrrolidine-2-carboxamide

Lincomycin Hydrochloride Impurity 34
Formula: C18H34N2O7S
422.54
RM-L140334
(2S,4R)-2-(((1R,2R)-2-hydroxy-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)carbamoyl)-1-methyl-4-propylpyrrolidine 1-oxide

Lincomycin Hydrochloride Impurity 35
CAS:16727-66-5
Formula: C21H38N2O6S
446.6
RM-L140335
(2S,4R)-N-((1R,2R)-2-hydroxy-1-((3aS,4R,6R,7R,7aR)-7-hydroxy-2,2-dimethyl-6-(methylthio)tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-4-yl)propyl)-1-methyl-4-propylpyrrolidine-2-carboxamide

Lincomycin Impurity 35
Formula: C18H33N2O8PS
468.5
RM-L140336
(2R,3R,4S,5R,6R)-4,5-dihydroxy-6-((E)-1-((2S,4R)-1-methyl-4-propylpyrrolidine-2-carboxamido)prop-1-en-1-yl)-2-(methylthio)tetrahydro-2H-pyran-3-yl dihydrogen phosphate

Lincomycin Impurity 37
Formula: C19H36N2O6S
420.57
RM-L140337
(2S,4R)-N-((1R,3S)-3-hydroxy-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)butyl)-1-methyl-4-propylpyrrolidine-2-carboxamide

Lincomycin Impurity 38
Formula: C17H32N2O6S
392.51
RM-L140338
(2R,4R)-N-((1R,2R)-2-hydroxy-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-4-propylpyrrolidine-2-carboxamide

Lincomycin Impurity 39
Formula: C34H64N2O7S
644.95
RM-L140339
(2R,3R,4S,5R,6R)-4,5-dihydroxy-6-((1R,2S)-2-hydroxy-1-((2S,4R)-1-methyl-4-propylpyrrolidine-2-carboxamido)propyl)-2-(methylthio)tetrahydro-2H-pyran-3-yl palmitate

Lincomycin Impurity 40
Formula: C18H34N2O6S
406.54
RM-L140340
(2S,4S)-N-((1R,2R)-2-hydroxy-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-1-methyl-4-propylpyrrolidine-2-carboxamide

Lincomycin Impurity 41
Formula: C18H34N2O6S
406.54
RM-L140341
(2R,4S)-N-((1R,2R)-2-hydroxy-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-1-methyl-4-propylpyrrolidine-2-carboxamide

Lincomycin Impurity 42
CAS:776994-56-0
Formula: C34H64N2O7S
644.95
RM-L140342
(2R,3R,4S,5R,6R)-4,5-dihydroxy-6-((1R,2R)-2-hydroxy-1-((2S,4R)-1-methyl-4-propylpyrrolidine-2-carboxamido)propyl)-2-(methylthio)tetrahydro-2H-pyran-3-yl palmitate

Lincomycin Impurity 43
Formula: C18H35N3O7S
437.55
RM-L140343
(R)-N-((1R,2R)-2-hydroxy-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-4-((methyl(nitroso)amino)methyl)heptanamide

Lincomycin Impurity 44
Formula: C18H35N3O7S
437.55
RM-L140344
(2S,4R)-N-((1R,2R)-2-hydroxy-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-4-methyl-2-(methyl(nitroso)amino)heptanamide

Lincomycin Impurity 45
Formula: C17H31N3O7S
421.51
RM-L140345
(2S,4R)-N-((1R,2R)-2-hydroxy-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-1-nitroso-4-propylpyrrolidine-2-carboxamide

Lincomycin Impurity 46
Formula: C17H32N2O6S
392.51
RM-L140346
(2S,4R)-4-ethyl-N-((1R,2R)-2-hydroxy-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-1-methylpyrrolidine-2-carboxamide

Lincomycin Impurity 47
Formula: C18H33N2O8PS
468.5
RM-L140347
(2S,4R)-N-((1R,2R)-1-((3aS,4R,6R,7R,7aR)-2,7-dihydroxy-6-(methylthio)-2-oxidotetrahydro-4H-[1,3,2]dioxaphospholo[4,5-c]pyran-4-yl)-2-hydroxypropyl)-1-methyl-4-propylpyrrolidine-2-carboxamide

Lincomycin Impurity 48
Formula: C18H32N2O6S
404.52
RM-L140348
N-((1R,2R)-2-hydroxy-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-1-methyl-4-propylidenepyrrolidine-2-carboxamide

Lincomycin Impurity 49
Formula: C17H32N2O8
392.45
RM-L140349
(2S,4R)-N-((1S,2R)-1,2-dihydroxy-1-((2S,3R,4S,5R)-3,4,5,6-tetrahydroxytetrahydro-2H-pyran-2-yl)propyl)-1-methyl-4-propylpyrrolidine-2-carboxamide

Lincomycin phosphate(USP);Clindamycin Phosphate EP Impurity F; Clindamycin Impurity G
CAS:27480-30-4
Formula: C18H35N2O9PS
486.52
RM-C120420
(2R,3R,4S,5R,6R)-4,5-dihydroxy-6-((1R,2R)-2-hydroxy-1-((2S,4R)-1-methyl-4-propylpyrrolidine-2-carboxamido)propyl)-2-(methylthio)tetrahydro-2H-pyran-3-yl dihydrogen phosphate

LINCOMYCIN SULFOXIDE (MIXTURE OF DIASTEREOMERS)
CAS:22083-92-7
Formula: C18H34N2O7S
422.54
RM-L140332
(2S,4R)-N-((1R,2R)-2-hydroxy-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfinyl)tetrahydro-2H-pyran-2-yl)propyl)-1-methyl-4-propylpyrrolidine-2-carboxamide

LINDANE
CAS:58-89-9
Formula: C6H6Cl6
290.83
RM-L090400
Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1+¦,2+¦,3+¦,4+¦,5+¦,6+¦)

LINEZOLID
CAS:165800-03-3
Formula: C16H20FN3O4
337.35
RM-L142600
N-[[(5S)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl] methyl] acetamide

LINEZOLID AMINE IMPURITY
CAS:93246-53-8
Formula: C10H13FN2O
196.22
RM-L142611
3-Fluoro-4-(morpholin-4-yl)phenylamine

LINEZOLID BENZYL IMPURITY
CAS:168828-81-7
Formula: C18H19FN2O3
330.35
RM-L142605
benzyl (3-fluoro-4-morpholinophenyl)carbamate

LINEZOLID DESACETAMIDE DESCARBONYL PHTHALIMIDE
CAS:874340-08-6
Formula: C21H22FN3O4
399.42
RM-L142610
N-(3-Phthalimido-2-(R)-hydroxypropyl)-3-fluoro-4-(morpholinyl)aniline

LINEZOLID DESACETAMIDE HYDROXY IMPURITY
CAS:168828-82-8
Formula: C14H17FN2O4
296.29
RM-L142606
(R)-3-(3-fluoro-4-morpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one

LINEZOLID DESACETAMIDE PHTHALIMIDE
CAS:168828-89-5
Formula: C22H20FN3O5
425.41
RM-L142609
(S)-N-[[3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl] methyl] phthalimide

LINEZOLID DESCARBONYL IMPURITY
CAS:333753-67-6
Formula: C15H22FN3O3
311.35
RM-L142607
N-[(2R)-3-[[3-Fluoro-4-(4-morpholinyl)phenyl]amino]-2-hydroxypropyl] acetamide

LINEZOLID DESFLUORO IMPURITY
CAS:556801-15-1
Formula: C16H21N3O4
319.36
RM-L142604
N-[[(5S)-3-[4-(4-Morpholinyl)phenyl]-2-oxo-5-oxazolidinyl] methyl] acetamide

LINEZOLID DIMER
CAS:908143-04-4
Formula: C30H35F2N5O7
615.63
RM-L142608
N,N-bis(((S)-3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

Linezolid Impurity 101
Formula: C14H19N3O4
293.32
RM-L142701
(S)-5-(aminomethyl)-3-(3-hydroxy-4-morpholinophenyl)oxazolidin-2-one

Linezolid Impurity 102
CAS:227200-81-9
Formula: C14H19N3O4
293.32
RM-L142702
(S)-N-((3-(4-((2-hydroxyethyl)amino)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

Linezolid Impurity 103
Formula: C35H44F2N6O9
730.77
RM-L142703
N,N'-(2-hydroxypropane-1,3-diyl)bis(N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide)

Linezolid Impurity 104
Formula: C17H20FN3O5
365.36
RM-L142704
(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)-N-formylacetamide

Linezolid Impurity 105
CAS:477846-96-1
Formula: C10H11BrN2O3
287.11
RM-L142705
4-(2-bromo-4-nitrophenyl)morpholine

Linezolid Impurity 106
Formula: C32H39F2N5O9
675.69
RM-L142706
N-(2-(((R)-3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methoxy)-2-hydroxyethyl)-N-(((S)-3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

Linezolid Impurity 107
Formula: C20H24F2N4O2
390.43
RM-L142707
1,2-bis(3-fluoro-4-morpholinophenyl)hydrazine

Linezolid Impurity 108
Formula: C20H22F2N4O2
388.42
RM-L142708
1,2-bis(3-fluoro-4-morpholinophenyl)diazene

Linezolid Impurity 109
Formula: C20H22F2N4O3
404.42
RM-L142709
1,2-bis(3-fluoro-4-morpholinophenyl)diazene 1-oxide

Linezolid Impurity 111
Formula: C24H25FN2O
376.48
RM-L142711
N,N-dibenzyl-3-fluoro-4-morpholinoaniline

LINEZOLID IMPURITY 112
Formula: C15H20FN3O2
293.34
RM-L142712
3-fluoro-N-((2-methyl-4,5-dihydrooxazol-5-yl)methyl)-4-morpholinoaniline

LINEZOLID IMPURITY 113
CAS:220954-15-4
Formula: C10H11FN2O3
226.21
RM-L142713
4-(3-fluoro-5-nitrophenyl)morpholine

LINEZOLID IMPURITY 114
Formula: C7H11NO3
157.17
RG-P022636
(3-acetyl-2-methyl-4,5-dihydrooxazol-3-ium-5-yl)methanolate

Linezolid Impurity 115
CAS:78692-88-3
Formula: C7H11ClO4
194.61
RG-P022637
(S)-3-chloropropane-1,2-diyl diacetate

Linezolid Impurity 116
CAS:216869-17-9
Formula: C17H22FN3O4
351.38
RM-L142716
(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)propionamide

Linezolid Impurity 117
CAS:168828-65-7
Formula: C15H18FN3O4
323.32
RM-L142717
(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)formamide

LINEZOLID IMPURITY 118
CAS:264601-17-4
Formula: C14H18N2O4
278.31
RM-L142718
(R)-5-(hydroxymethyl)-3-(4-morpholinophenyl)oxazolidin-2-one

LINEZOLID IMPURITY 119
CAS:2180529-06-8
Formula: C14H17FN2O4
296.3
RM-L142719
(S)-3-(3-fluoro-4-morpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one

Linezolid Impurity 120
CAS:556801-09-3
Formula: C15H20N2O6S
356.39
RM-L142720
(R)-(3-(4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate

Linezolid Impurity 121
CAS:2180621-71-8
Formula: C15H19FN2O6S
374.38
RM-L142721
(S)-(3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate

LINEZOLID IMPURITY 122
CAS:556801-12-8
Formula: C22H21N3O5
407.43
RM-L142722
(S)-2-((3-(4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)isoindoline-1,3-dione

LINEZOLID IMPURITY 123
Formula: C17H24FN3O4
353.39
RM-L142723
(S)-N-(3-acetamido-2-hydroxypropyl)-N-(3-fluoro-4-morpholinophenyl)acetamide

Linezolid Impurity 124
Formula: C16H20FN3O3S
353.41
RM-L142724
N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)ethanethioamide

Linezolid Impurity 125
Formula: C17H24FN3O4
353.39
RM-L142725
1-amino-3-(N-(3-fluoro-4-morpholinophenyl)acetamido)propan-2-yl acetate

LINEZOLID IMPURITY 126
Formula: C29H35F2N5O6
587.62
RM-L142726
(5S,5'S)-5,5'-((methylazanediyl)bis(methylene))bis(3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one)

LINEZOLID IMPURITY 127
Formula: C5H10ClNO2
151.59
RM-L142727
(R)-N-(3-chloro-2-hydroxypropyl)acetamide

Linezolid Impurity 128
Formula: C15H22FN3O3
311.36
RM-L142728
1-amino-3-((3-fluoro-4-morpholinophenyl)amino)propan-2-yl acetate

Linezolid Impurity 129
Formula: C23H23N3O7
453.45
RM-L142729
methyl (S)-2-(((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)carbamoyl)benzoate

LINEZOLID IMPURITY 130
Formula: C23H28FN3O5
445.49
RM-L142730
benzyl (S)-(3-acetamido-2-hydroxypropyl)(3-fluoro-4-morpholinophenyl)carbamate

LINEZOLID IMPURITY 131
Formula: C22H20FN3O5
425.42
RM-L142731
2-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)isoindoline-1,3-dione

LINEZOLID IMPURITY 132
Formula: C16H22FN3O3
323.37
RM-L142732
(S)-5-((dimethylamino)methyl)-3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one

Linezolid Impurity 133
Formula: C15H20FN3O3
309.34
RM-L142733
(S)-3-(3-fluoro-4-morpholinophenyl)-5-((methylamino)methyl)oxazolidin-2-one

Linezolid Impurity 134
CAS:1215006-11-3
Formula: C20H28FN3O4
393.46
RM-L142734
(S)-N-(tert-butyl)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

Linezolid Impurity 135
CAS:1215006-08-8
Formula: C18H26FN3O3
351.42
RM-L142735
(S)-5-((tert-butylamino)methyl)-3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one

Linezolid Impurity 136
CAS:725676-93-7
Formula: C3H8ClNO
109.55
RM-L142736
2-amino-3-chloropropan-1-ol

Linezolid Impurity 137
Formula: C5H7N3O2
141.13
RM-L142737
N-carbamoyl-2-cyano-N-methylacetamide

Linezolid Impurity 138
CAS:1429374-38-8
Formula: C5H10ClNO2
151.59
RM-L142738
(S)-1-amino-3-chloropropan-2-yl acetate

Linezolid Impurity 139
CAS:588708-63-8
Formula: C10H11FN2O2
210.21
RM-L142739
4-(2-fluoro-4-nitrosophenyl)morpholine

Linezolid Impurity 140
Formula: C10H13FN2O2
212.22
RM-L142740
N-(3-fluoro-4-morpholinophenyl)hydroxylamine

Linezolid Impurity 141
CAS:209960-29-2
Formula: C10H13FN2O
196.23
RM-L142741
2-fluoro-4-morpholinoaniline

Linezolid Impurity 142
Formula: C11H11NO4
221.21
RM-L142742
2-cyanoethyl 2-(2,5-dimethylfuran-3-yl)-2-oxoacetate

Linezolid Impurity 145
CAS:500206-01-9
Formula: C10H13FN2O
196.23
RM-L142745
2-fluoro-5-morpholinoaniline

Linezolid Impurity 146
CAS:258864-18-5
Formula: C10H13FN2O
196.23
RM-L142746
3-Fluoro-5-morpholinoaniline

Linezolid Impurity 147
CAS:232951-87-0
Formula: C10H13FN2O
196.23
RM-L142747
4-Fluoro-2-morpholinoaniline

Linezolid Impurity 148
CAS:1233952-34-5
Formula: C10H13FN2O
196.23
RM-L142748
3-Fluoro-2-morpholinoaniline

Linezolid Impurity 149
CAS:1802413-79-1
Formula: C10H13FN2O
196.23
RM-L142749
2-fluoro-3-morpholinoaniline

Linezolid Impurity 150
CAS:179900-22-2
Formula: C10H13FN2O
196.23
RM-L142750
2-fluoro-6-morpholinoaniline

LINEZOLID IMPURITY 17
CAS:15708-41-5
Formula: C10H12FeN2NaO8
367.05
RM-L142617
iron(III) sodium 2,2',2'',2'''-(ethane-1,2-diylbis(azanetriyl))tetraacetate

LINEZOLID IMPURITY 24
CAS:1138458-15-7
Formula: C13H14ClFN2O3
300.71
RM-L142624
(R)-5-chloro-3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one

LINEZOLID IMPURITY 25
CAS:212325-40-1
Formula: C12H15FN2O3
254.26
RM-L142625
methyl (3-fluoro-4-morpholinophenyl)carbamate

LINEZOLID IMPURITY 26
CAS:348626-43-7
Formula: C18H20N2O3
312.36
RM-L142626
benzyl (4-morpholinophenyl)carbamate

LINEZOLID IMPURITY 27
CAS:10389-51-2
Formula: C10H12N2O3
208.21
RM-L142627
4-(4-Nitrophenyl)morpholine

LINEZOLID IMPURITY 29
CAS:2512211-93-5
Formula: C15H20FN3O2
293.34
RM-L142629
1-(3-fluoro-4-morpholinophenyl)-2-methyl-1,4,5,6-tetrahydropyrimidin-5-ol

LINEZOLID IMPURITY 31
Formula: C21H29FN4O6
452.48
RM-L142631
N-((S)-3-acetamido-2-hydroxypropyl)-N-(((S)-3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

LINEZOLID IMPURITY 32
CAS:589489-13-4
Formula: C12H19Cl2NO5
328.19
RM-L142632
(2S,2'S)-(acetylazanediyl)bis(1-chloropropane-3,2-diyl) diacetate

LINEZOLID IMPURITY 34
Formula: C23H25FN4O5
456.47
RM-L142634
(S)-N1-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)-N2-methylphthalamide

LINEZOLID IMPURITY 35
CAS:952680-48-7
Formula: C15H21FN2O3
296.34
RM-L142635
tert-butyl (3-fluoro-4-morpholinophenyl)carbamate

LINEZOLID IMPURITY 36
Formula: C17H22FN3O4
351.37
RM-L142636
(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)-N-methylacetamide

LINEZOLID IMPURITY 37
CAS:1798014-14-8
Formula: C32H31FN4O7
602.61
RM-L142637
2-((R)-3-(((S)-3-(1,3-dioxoisoindolin-2-yl)-2-hydroxypropyl)(3-fluoro-4-morpholinophenyl)amino)-2-hydroxypropyl)isoindoline-1,3-dione

LINEZOLID IMPURITY 38
CAS:1219708-30-1
Formula: C14H18FN3O4
311.31
RM-L142638
(S)-N-((3-(3-fluoro-4-((2-hydroxyethyl)amino)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

Linezolid Impurity 39; N-Phthalyl-L-Alanine
CAS:4192-28-3
Formula: C11H9NO4
219.19
RM-L142639
(S)-2-(1,3-Dioxoisoindolin-2-yl)propanoic acid

LINEZOLID IMPURITY 40
CAS:183905-31-9
Formula: C7H12ClNO3
193.63
RM-L142640
(S)-1-Acetamido-3-chloropropan-2-yl acetate

LINEZOLID IMPURITY 41
Formula: C21H26FN3O4
403.45
RM-L142641
benzyl (3-amino-2-hydroxypropyl)(3-fluoro-4-morpholinophenyl)carbamate

LINEZOLID IMPURITY 42
Formula: C25H29F2N5O5
517.53
RM-L142642
1-(3-fluoro-4-morpholinophenyl)-3-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)urea

LINEZOLID IMPURITY 43
Formula: C21H29FN4O6
452.48
RM-L142643
N-(3-acetamido-2-hydroxypropyl)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

LINEZOLID IMPURITY 44
Formula: C20H26FN3O5
407.44
RM-L142644
(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)-N-(3-oxobutyl)acetamide

LINEZOLID IMPURITY 45
Formula: C25H25FN2O4
436.48
RM-L142645
4-(4-(benzyl((benzyloxy)carbonyl)amino)-2-fluorophenyl)morpholine 4-oxide

LINEZOLID IMPURITY 46
Formula: C25H25FN2O4
436.48
RM-L142646
Linezolid Impurity 46

LINEZOLID IMPURITY 47
CAS:174649-09-3
Formula: C15H19FN2O6S
374.38
RM-L142647
(R)-(3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate

LINEZOLID IMPURITY 49
Formula: C21H23N3O4
381.43
RM-L142649
(R)-2-(2-hydroxy-3-((4-morpholinophenyl)amino)propyl)isoindoline-1,3-dione

LINEZOLID IMPURITY 50
CAS:565176-83-2
Formula: C13H17FN2O3
268.28
RM-L142650
ethyl (3-fluoro-4-morpholinophenyl)carbamate

LINEZOLID IMPURITY 51
Formula: C33H41F2N5O9
689.71
RM-L142651
N-(3-(((R)-3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methoxy)-2-hydroxypropyl)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

LINEZOLID IMPURITY 52
CAS:858344-36-2
Formula: C15H19FN2O6S
374.38
RM-L142652
(3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate

LINEZOLID IMPURITY 53
CAS:1391062-33-1
Formula: C15H20FN3O2
293.34
RM-L142653
N-(3-((3-fluoro-4-morpholinophenyl)imino)propyl)acetamide

LINEZOLID IMPURITY 54
Formula: C21H24F2N4O3
418.44
RM-L142654
1,3-bis(3-fluoro-4-morpholinophenyl)urea

LINEZOLID IMPURITY 56
Formula: C13H17FN2O2
252.28
RM-L142656
(R)-3-Fluoro-4-morpholino-N-(oxiran-2-ylmethyl)aniline

LINEZOLID IMPURITY 57
CAS:496031-57-3
Formula: C14H16ClFN2O3
314.74
RM-L142657
(R)-5-(Chloromethyl)-3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one

LINEZOLID IMPURITY 58
Formula: C14H16ClFN2O3
314.74
RM-L142658
(S)-5-(chloromethyl)-3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one

LINEZOLID IMPURITY 59
CAS:333753-71-2
Formula: C15H22FN3O3
311.35
RM-L142659
(S)-1-amino-3-((3-fluoro-4-morpholinophenyl)amino)propan-2-yl acetate

Linezolid Impurity 60
Formula: C36H38F2N6O8
720.72
RM-L142660
N1,N2-bis(((S)-3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)phthalamide

LINEZOLID IMPURITY 61
Formula: C22H22D3FN4O4
431.48
RM-L142661
Linezolid Impurity 61

LINEZOLID IMPURITY 62
Formula: C22H25FN4O4
428.46
RM-L142662
(S)-N-((3-(3-fluoro-4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

LINEZOLID IMPURITY 63
Formula: C22H25FN4O4
428.46
RM-L142663
(S)-N-((3-(3-fluoro-4-(4-(2-hydroxyphenyl)piperazin-1-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

LINEZOLID IMPURITY 64
Formula: C22H25FN4O4
428.46
RM-L142664
(S)-N-((3-(3-fluoro-4-(4-(3-hydroxyphenyl)piperazin-1-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

LINEZOLID IMPURITY 65
CAS:1233093-70-3
Formula: C10H11FN2O3
226.2
RM-L142665
4-(2-fluoro-5-nitrophenyl)morpholine

LINEZOLID IMPURITY 68
Formula: C33H41F2N5O9
689.7
RM-L142668
N-(3-(((R)-3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methoxy)-2-hydroxypropyl)-N-(((S)-3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

LINEZOLID IMPURITY 69
CAS:384344-17-6
Formula: C10H12FNO
181.21
RM-L142669
4-(2-fluorophenyl)morpholine

LINEZOLID IMPURITY 70
CAS:224323-52-8
Formula: C10H12ClNO
197.66
RM-L142670
(S)-1-(benzylideneamino)-3-chloropropan-2-ol

Linezolid Impurity 71
Formula: C9H18N2O3
202.25
RM-L142671
(S)-1-acetamido-3-(dimethylamino)propan-2-yl acetate

LINEZOLID IMPURITY 72
CAS:183805-10-9
Formula: C5H9NO2
115.13
RM-L142672
(S)-N-(oxiran-2-ylmethyl)acetamide

Linezolid Impurity 73
Formula: C5H9NO2
115.13
RM-L142673
(R)-(2-methyl-4,5-dihydrooxazol-5-yl)methanol

Linezolid Impurity 74
Formula: C14H19N3O4
293.32
RM-L142674
4,4'-(4-nitro-1,2-phenylene)dimorpholine

LINEZOLID IMPURITY 75
CAS:952288-54-9
Formula: C14H19N3O3
277.32
RM-L142675
(S)-5-(aminomethyl)-3-(4-morpholinophenyl)oxazolidin-2-one

LINEZOLID IMPURITY 76
CAS:1561176-27-9
Formula: C15H22FN3O3
311.35
RM-L142676
(S)-N-(3-((3-fluoro-4-morpholinophenyl)amino)-2-hydroxypropyl)acetamide

LINEZOLID IMPURITY 77
CAS:1394245-06-7
Formula: C16H22FN3O5
355.36
RM-L142677
(S)-(3-acetamido-2-hydroxypropyl)(3-fluoro-4-morpholinophenyl)carbamic acid

LINEZOLID IMPURITY 78
CAS:1532560-87-4
Formula: C13H20FN3O2
269.32
RM-L142678
1-amino-3-((3-fluoro-4-morpholinophenyl)amino)propan-2-ol

LINEZOLID IMPURITY 79 (R-LINEZOLID DESACETAMIDE PHTHALIMIDE)
CAS:947736-16-5
Formula: C22H20FN3O5
425.42
RM-L142679
(R)-2-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)isoindoline-1,3-dione

Linezolid Impurity 81
Formula: C15H18FNO4
295.31
RM-L142681
(5R)-3-(3-fluoro-4-morpholinophenyl)-5-(hydroxymethyl)dihydrofuran-2(3H)-one

Linezolid Impurity 82
CAS:1175797-88-2
Formula: C10H13FN2O
196.23
RM-L142682
4-fluoro-3-morpholinoaniline

Linezolid Impurity 84
CAS:2307625-63-2
Formula: C28H33F2N5O6
573.6
RM-L142684
(5S,5'S)-5,5'-(azanediylbis(methylene))bis(3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one)

Linezolid Impurity 85
Formula: C21H29FN4O6
452.48
RM-L142685
N-(3-acetamido-2-hydroxypropyl)-N-(((S)-3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

Linezolid Impurity 86
CAS:1373348-82-3
Formula: C22H21ClFN3O5
461.87
RM-L142686
(S)-1-chloro-3-(1,3-dioxoisoindolin-2-yl)propan-2-yl (3-fluoro-4-morpholinophenyl)carbamate

Linezolid Impurity 87
CAS:872991-73-6
Formula: C17H19FN2O
286.35
RM-L142687
N-benzyl-3-fluoro-4-morpholinoaniline

LINEZOLID IMPURITY 88
Formula: C21H24FN3O3
385.44
RM-L142688
(S)-5-((benzylamino)methyl)-3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one

LINEZOLID IMPURITY 89
CAS:55435-71-7
Formula: C10H11ClN2O3
242.66
RM-L142689
4-(2-chloro-4-nitrophenyl)morpholine

Linezolid Impurity 90
CAS:55048-24-3
Formula: C10H13ClN2O
212.68
RM-L142690
3-Chloro-4-morpholinoaniline

Linezolid Impurity 91
Formula: C18H19FN2O3
330.36
RM-L142691
benzyl (4-fluoro-3-morpholinophenyl)carbamate

Linezolid Impurity 92
CAS:224323-49-3
Formula: C5H9NO2
115.13
RM-L142692
N-(oxiran-2-ylmethyl)acetamide

Linezolid Impurity 93
CAS:152139-76-9
Formula: C5H11NO3
133.15
RM-L142693
(S)-N-(2,3-dihydroxypropyl)acetamide

Linezolid Impurity 94
Formula: C6H13NO3
147.17
RM-L142694
(S)-N-(2-hydroxy-3-methoxypropyl)acetamide

Linezolid Impurity 95
Formula: C12H17NO3
223.27
RM-L142695
(S)-N-(3-(benzyloxy)-2-hydroxypropyl)acetamide

Linezolid Impurity 96
CAS:1644566-11-9
Formula: C16H20FN3O4
337.35
RM-L142696
(S)-N-((3-(4-fluoro-3-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

Linezolid Impurity 97
CAS:2369879-47-8
Formula: C16H18FN3O6
367.33
RM-L142697
(S)-2-(N-(4-(5-(acetamidomethyl)-2-oxooxazolidin-3-yl)-2-fluorophenyl)formamido)ethyl formate

Linezolid Impurity 98
Formula: C15H18FN3O5
339.32
RM-L142698
(S)-N-((3-(3-Fluoro-4-(N-(2-hydroxyethyl)formamido)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

Linezolid Impurity 99
Formula: C15H22FN3O3
311.36
RM-L142699
N-(3-amino-2-hydroxypropyl)-N-(3-fluoro-4-morpholinophenyl)acetamide

LINEZOLID IMPURITY D
Formula: C7H12ClNO3
193.63
RM-L142612
(R)-1-acetamido-3-chloropropan-2-yl acetate

LINEZOLID IMPURITY E
CAS:224323-47-1
Formula: C5H10ClNO2
151.59
RM-L142613
(S)-N-(3-chloro-2-hydroxypropyl)acetamide

LINEZOLID IMPURITY F
CAS:2689-39-6
Formula: C10H11FN2O3
226.2
RM-L142614
4-(2-FLUORO-4-NITROPHENYL)MORPHOLINE

Linezolid Impurity G
Formula: C30H35F2N5O7
615.63
RM-L142615
N-(((R)-3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)-N-(((S)-3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

LINEZOLID IMPURITY H
CAS:2524-67-6
Formula: C10H14N2O
178.23
RM-L142616
4-Morpholinoaniline

Linezolid Impurity I (Pnu142063)
CAS:1391068-25-9
Formula: C15H22FN3O3 HCl
311.36 36.46
RM-L122605
(S)-N-(3-amino-2-hydroxypropyl)-N-(3-fluoro-4-morpholinophenyl)acetamide hydrochloride

Linezolid Impurity J
Formula: C15H22FN3O3
311.35
RM-L142618
(R)-1-amino-3-((3-fluoro-4-morpholinophenyl)amino)propan-2-yl acetate

LINEZOLID IMPURITY K
CAS:496031-56-2
Formula: C16H19FN2O5
338.33
RM-L142620
(R)-(3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl acetate

LINEZOLID IMPURITY L
CAS:1807854-53-0
Formula: C12H15FN2O2
238.26
RM-L142621
N-(3-fluoro-4-morpholinophenyl)acetamide

LINEZOLID IMPURITY M
CAS:333753-72-3
Formula: C13H20FN3O2
269.32
RM-L142622
(S)-1-Amino-3-((3-fluoro-4-morpholinophenyl)amino)propan-2-ol

Linezolid Impurity N
Formula: C16H20FN3O4
337.35
RM-L142623
N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

LINEZOLID IMPURITY S
CAS:5394-50-3
Formula: C16H16N2O4
300.31
RM-L142619
Dibenzyl hydrazine-1,2-dicarboxylate

LINEZOLID N-OXIDE
CAS:189038-36-6
Formula: C16H20FN3O5
353.35
RM-L142633
(S)-4-(4-(5-(acetamidomethyl)-2-oxooxazolidin-3-yl)-2-fluorophenyl)morpholine 4-oxide

Linezolid Nitroso Impurity 143
Formula: C15H21FN4O4
340.36
RM-L142743
(R)-N-(3-((3-fluoro-4-morpholinophenyl)(nitroso)amino)-2-hydroxypropyl)acetamide

Linezolid Nitroso Impurity 144
Formula: C16H19FN4O6
382.35
RM-L142744
(R)-N-((3-(3-fluoro-4-(nitroso(2-(2-oxoethoxy)ethyl)amino)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

LINEZOLID USP RC A
CAS:168828-84-0
Formula: C14H16FN5O3
321.31
RM-L142601
(5R)-5-(Azidomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxazolidinone

LINEZOLID USP RC B
CAS:216868-57-4
Formula: C16H20FN3O3S
353.41
RM-L142602
(S)-N-{[3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl]methyl} thioacetamide

LINEZOLID USP RC C
CAS:168828-90-8
Formula: C14H18FN3O3
295.31
RM-L142603
(S)-5-(aminomethyl)-3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one

LINEZOLID-D3
CAS:1127120-38-0
Formula: C16H17D3FN3O4
340.36
RM-L142667
(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide-2,2,2-d3

LINEZOLID-D8
CAS:1032182-14-1
Formula: C16H12D8FN3O4
345.4
RM-L142666
Linezolid-D8

LINOLENIC ACID
CAS:463-40-1
Formula: C18H30O2
278.43
RM-L090501
(9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid

LINOLEYL ALCOHOL
CAS:506-43-4
Formula: C18H34O
266.47
RG-E141481
(9Z,12Z)-Octadeca-9,12-dien-1-ol

Linoleyl lysophosphatidylcholine
CAS:22252-07-9
Formula: C26H50NO7P
519.66
RM-L271004
1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC; (R)-2-hydroxy-3-(((9Z,12Z)-octadeca-9,12-dienoyl)oxy)propyl (2-(trimethylammonio)ethyl) phosphate

LINURON
CAS:330-55-2
Formula: C9H10Cl2N2O2
249.09
RG-A260693
LINURON

LINZAGOLIX
CAS:935283-04-8
Formula: C22H15F3N2O7S
508.42
RM-L230000
3-(5-((2,3-difluoro-6-methoxybenzyl)oxy)-2-fluoro-4-methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylic acid

LINZAGOLIX CHOLINE
CAS:1321816-57-2
Formula: C22H14F3N2O7S*C5H14NO
507.42*104.17
RM-L230007
2-hydroxy-N,N,N-trimethylethan-1-aminium 3-(5-((2,3-difluoro-6-methoxybenzyl)oxy)-2-fluoro-4-methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylate

Linzagolix Impurity 1
Formula: C7H7NO4S
201.2
RM-L230001
4-amino-3-(methoxycarbonyl)thiophene-2-carboxylic acid

Linzagolix Impurity 2
Formula: C7H7NO4S
201.2
RM-L230002
4-amino-2-(methoxycarbonyl)thiophene-3-carboxylic acid

Linzagolix Impurity 3
CAS:2218504-94-8
Formula: C7H6FNO4
187.13
RM-L230003
4-fluoro-2-methoxy-6-nitrophenol

Linzagolix Impurity 4
CAS:1033103-05-7
Formula: C7H8FNO2
157.14
RM-L230004
2-amino-4-fluoro-6-methoxyphenol

Linzagolix Impurity 5
CAS:2168201-68-9
Formula: C6H6FNO2
143.12
RM-L230005
4-amino-5-fluorobenzene-1,2-diol

Linzagolix Impurity 6
Formula: C12H16FNO4
257.26
RM-L230006
tert-butyl (5-fluoro-2-hydroxy-3-methoxyphenyl)carbamate

LIOTHYRONINE SODIUM
CAS:55-06-1
Formula: C15H12I3NO4*Na
672.96
RM-L091500
sodium (S)-2-amino-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoate

Liothyronine Sodium EP Impurity B
CAS:300-39-0
Formula: C9H9I2NO3
432.98
RM-L091502
(S)-2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid

Lipoic Acid Impurity 1
Formula: C18H32N2O2S4
436.72
RM-L091627
N,N'-(ethane-1,2-diyl)bis(5-(1,2-dithiolan-3-yl)pentanamide)

Lipoic Acid Impurity 10(Impurity C1)
CAS:2114407-82-6
Formula: C8H14O3S2
222.32
RM-L091636
5-((2S)-2-oxido-1,2-dithiolan-3-yl)pentanoic acid

Lipoic Acid Impurity 11 (Impurity D)
CAS:2114407-76-8
Formula: C8H14O3S2
222.32
RM-L091637
5-((1R)-1-oxido-1,2-dithiolan-3-yl)pentanoic acid

Lipoic Acid Impurity 12(Impurity C2)
CAS:2114407-78-0
Formula: C8H14O3S2
222.32
RM-L091638
5-((1S)-1-oxido-1,2-dithiolan-3-yl)pentanoic acid

Lipoic Acid Impurity 13
CAS:41443-60-1
Formula: C8H14Cl2O2
213.1
RM-L091639
6,8-dichlorooctanoic acid

Lipoic Acid Impurity 14
Formula: C8H14O3S2
222.32
RM-L091640
5-((3R)-2-oxido-1,2-dithiolan-3-yl)pentanoic acid/5-((3R)-1-oxido-1,2-dithiolan-3-yl)pentanoic acid

LIPOIC ACID IMPURITY 15
CAS:1071-71-2
Formula: C8H13ClO3
192.64
RM-L091641
ethyl 6-chloro-6-oxohexanoate

Lipoic Acid Impurity 16
Formula: C9H16O2S2
220.35
RM-L091642
5-(5-methyl-1,2-dithiolan-3-yl)pentanoic acid

Lipoic Acid Impurity 17
CAS:46236-19-5
Formula: C9H16O2S2
220.35
RM-L091643
methyl 5-(1,2-dithiolan-3-yl)pentanoate

Lipoic Acid Impurity 18
Formula: C6H10O2S2
178.27
RM-L091644
3-(1,2-dithiolan-3-yl)propanoic acid

Lipoic Acid Impurity 19
Formula: C6H10O3S2
194.27
RM-L091645
3-(1,2-dithiolan-3-yl)-3-hydroxypropanoic acid

Lipoic Acid Impurity 2
CAS:462-20-4
Formula: C8H16O2S2
208.34
RM-L091628
6,8-dimercaptooctanoic acid

Lipoic Acid Impurity 20
Formula: C4H6O2S2
150.22
RM-L091646
1,2-Dithiolane-3-carboxylic acid

Lipoic Acid Impurity 21
Formula: C9H16O2S2
220.35
RM-L091647
5-(1,2-dithian-3-yl)pentanoic acid

Lipoic Acid Impurity 22
CAS:25636-58-2
Formula: C8H14O2S
174.26
RM-L091648
5-(thietan-2-yl)pentanoic acid

Lipoic Acid Impurity 23
CAS:940-69-2
Formula: C8H15NOS2
205.34
RM-L091649
5-(1,2-dithiolan-3-yl)pentanamide

LIPOIC ACID IMPURITY 24
CAS:50628-92-7
Formula: C10H16O3
184.23
RM-L091650
ethyl 6-oxooct-7-enoate

LIPOIC ACID IMPURITY 26
CAS:74903-53-0
Formula: C8H16O4
176.21
RM-L091652
6,8-dihydroxyoctanoic acid

LIPOIC ACID IMPURITY 27
CAS:90435-60-2
Formula: C8H15ClO3
194.66
RM-L091653
8-chloro-6-hydroxyoctanoic acid

LIPOIC ACID IMPURITY 28
CAS:91009-30-2
Formula: C10H20O2S2
236.39
RM-L091654
6,8-bis(methylthio)octanoic acid

LIPOIC ACID IMPURITY 29
CAS:1700-12-5
Formula: C10H18O6
234.25
RM-L091655
bis(2-hydroxyethyl) adipate

Lipoic Acid Impurity 3; Rac-Lipoic Acid Impurity 1 (S-Oxide)
CAS:108015-78-7
Formula: C8H14O3S2
222.32
RM-L091629
5-(2-oxido-1,2-dithiolan-3-yl)pentanoic acid

Lipoic Acid Impurity 31
Formula: C8H14O3S2
222.32
RM-L091657
5-(2-oxido-1,2-dithiolan-3-yl)pentanoic acid/5-(1-oxido-1,2-dithiolan-3-yl)pentanoic acid

LIPOIC ACID IMPURITY 32
CAS:119365-69-4
Formula: C8H16O2S2
208.34
RM-L091658
(R)-6,8-dimercaptooctanoic acid

Lipoic Acid Impurity 33
CAS:188745-24-6
Formula: C8H14O3S2
222.32
RM-L091659
5-((3R)-2-oxido-1,2-dithiolan-3-yl)pentanoic acid

Lipoic Acid Impurity 34
Formula: C8H14O3S2
222.32
RM-L091660
5-((3S)-2-oxido-1,2-dithiolan-3-yl)pentanoic acid

Lipoic Acid Impurity 35
Formula: C8H14O3S2
222.32
RM-L091661
5-((3S)-1-oxido-1,2-dithiolan-3-yl)pentanoic acid

Lipoic Acid Impurity 36
CAS:188783-96-2
Formula: C8H14O3S2
222.32
RM-L091662
5-((3R)-1-oxido-1,2-dithiolan-3-yl)pentanoic acid

Lipoic Acid Impurity 37
Formula: C8H14O3S2
222.32
RM-L091663
5-((2S,3R)-2-oxido-1,2-dithiolan-3-yl)pentanoic acid/5-((1R,3R)-1-oxido-1,2-dithiolan-3-yl)pentanoic acid

Lipoic Acid Impurity 38
Formula: C16H28O4S4
412.65
RM-L091664
5,5'-(1,2,6,7-tetrathiecane-3,8-diyl)dipentanoic acid

Lipoic Acid Impurity 4
Formula: C8H14O4S2
238.32
RM-L091630
5-(2,2-dioxido-1,2-dithiolan-3-yl)pentanoic acid

LIPOIC ACID IMPURITY 40
CAS:100386-08-1
Formula: C12H24O2S2
264.45
RM-L091666
ethyl 6,8-bis(methylthio)octanoate

Lipoic Acid Impurity 41
Formula: C16H26O5S4
426.63
RM-L091667
5-(1-oxido-1,2-dithiolan-3-yl)pentanoic anhydride

LIPOIC ACID IMPURITY 42
CAS:91140-37-3
Formula: C10H18O2S
202.31
RM-L091668
ethyl 5-(thietan-2-yl)pentanoate

Lipoic Acid Impurity 43
CAS:91009-31-3
Formula: C10H20O2S2
236.39
RM-L091669
ethyl 6,8-dimercaptooctanoate

Lipoic Acid Impurity 44
Formula: C10H18O2S
202.31
RM-L091670
(E)-ethyl 8-mercaptooct-5-enoate

Lipoic Acid Impurity 45
Formula: C12H20N2OS2
272.43
RM-L091671
N-(2-aminoethyl)-5-(2,3-dithioxocyclopentyl)pentanamide

LIPOIC ACID IMPURITY 46
CAS:2635383-46-7
Formula: C10H18O2S3
266.43
RM-L091672
ethyl 5-(1,2,3-trithian-4-yl)pentanoate

Lipoic Acid Impurity 47
Formula: C8H14O3S2
222.32
RM-L091673
5-((1S,3R)-1-oxido-1,2-dithiolan-3-yl)pentanoic acid

Lipoic Acid Impurity 48
Formula: C8H14O3S2
222.32
RM-L091674
5-((2R,3R)-2-oxido-1,2-dithiolan-3-yl)pentanoic acid

Lipoic Acid Impurity 49
Formula: C8H14O3S2
222.32
RM-L091675
5-((1R,3R)-1-oxido-1,2-dithiolan-3-yl)pentanoic acid

Lipoic Acid Impurity 5; Thioctic Acid Impurity 2
CAS:17370-41-1
Formula: C8H14O4S2
238.32
RM-L091631
5-(1,1-dioxido-1,2-dithiolan-3-yl)pentanoic acid

Lipoic Acid Impurity 50
Formula: C8H14O3S2
222.32
RM-L091676
5-((2S,3R)-2-oxido-1,2-dithiolan-3-yl)pentanoic acid

Lipoic Acid Impurity 51
Formula: C12H24N4O2S2
320.47
RM-L091677
ethyl 6,8-bis(carbamimidoylthio)octanoate

Lipoic Acid Impurity 52
Formula: C24H42O6S6
618.95
RM-L091678
5,5',5''-(1,2,6,7,11,12-hexathiacyclopentadecane-3,8,15-triyl)tripentanoic acid

Lipoic Acid Impurity 53
CAS:2140286-94-6
Formula: C8H14O4S2
238.32
RM-L091679
(R)-5-(2,2-dioxido-1,2-dithiolan-3-yl)pentanoic acid

Lipoic Acid Impurity 54
CAS:120476-62-2
Formula: C8H13ClO2
176.64
RG-A263520
7-(2-chloroethyl)oxepan-2-one

Lipoic Acid Impurity 55
Formula: C8H14O3S
190.26
RM-L091680
5-(1-oxidothietan-2-yl)pentanoic acid

Lipoic Acid Impurity 56
Formula: C15H20O2
232.32
RM-L091682
ethyl (E)-6-(p-tolyl)hex-4-enoate

Lipoic Acid Impurity 6
Formula: C8H14O4S2
238.32
RM-L091632
5-(1,2-dioxido-1,2-dithiolan-3-yl)pentanoic acid

Lipoic Acid Impurity 7
Formula: C16H28O6S4
444.65
RM-L091633
5,5'-(1,6-dioxido-1,2,6,7-tetrathiecane-3,10-diyl)dipentanoic acid

Lipoic Acid Impurity 8
Formula: C20H37NO6S4 C4H11NO3
515.77 121.14
RM-L091634
2-amino-2-(hydroxymethyl)propane-1,3-diol 5-(10-(5-((1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)amino)-5-oxopentyl)-1,2,6,7-tetrathiecan-3-yl)pentanoate

Lipoic Acid Impurity 9(Impurity E)
CAS:2114407-83-7
Formula: C8H14O3S2
222.32
RM-L091635
5-((2R)-2-oxido-1,2-dithiolan-3-yl)pentanoic acid

LIPOIC ACID IMPURITY A
CAS:728854-75-9
Formula: C10H20N2OS2
248.41
RM-L091601
N-(2-aminoethyl)-5-(1,2-dithiolan-3-yl)pentanamide

Lipoic Acid Impurity C (C1+C2)
CAS:2114407-82-6+2114407-78-0
Formula: C8H14O3S2
222.32
RM-L091656
5-((1S)-1-oxido-1,2-dithiolan-3-yl)pentanoic acid/5-((2S)-2-oxido-1,2-dithiolan-3-yl)pentanoic acid

Lipoic Acid Impurity39
CAS:6718-96-3
Formula: C16H28O4S4
412.65
RM-L091665
5,5'-(1,2,6,7-tetrathiecane-3,10-diyl)dipentanoic acid

LIPOPEPTIDE ACETATE
CAS:171263-26-6
Formula: C38H68N6O8
736.97
RM-L161600
Lipopeptide Acetate

LIQUIRITIGENIN
CAS:578-86-9
Formula: C15H12O4
256.26
RM-L091704
(S)-7-Hydroxy-2-(4-hydroxyphenyl)chroman-4-one

LIQUIRITIN
CAS:551-15-5
Formula: C21H22O9
418.4
RM-L091702
7-Hydroxyflavanone 4GÇ¦-O-glucoside; (S)-7-hydroxy-2-(4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)chroman-4-one

LIQUIRITIN APIOSIDE
CAS:74639-14-8
Formula: C26H30O13
550.51
RM-L091701
(S)-2-(4-(((2S,3R,4S,5S,6R)-3-(((2S,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-7-hydroxychroman-4-one

Liquiritinapioside
CAS:199796-12-8
Formula: C26H30O13
550.51
RM-L091700
(S)-7-(((2S,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-2-(4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)chroman-4-one

LIRAGLUTIDE
CAS:204656-20-2
Formula: C172H265N43O51
3751.26
RM-L090100
Liraglutide

Liraglutide Impurity 1
Formula: C25H40N2O9
512.6
RM-L090101
(R)-16-((1-carboxy-4-((2,5-dioxopyrrolidin-1-yl)oxy)-4-oxobutyl)amino)-16-oxohexadecanoic acid

Liraglutide Impurity 10
Formula: C35H39N5O6
625.73
RM-L090110
Na-(tert-butoxycarbonyl)-Nt-trityl-L-histidyl-L-alanylglycine

Liraglutide Impurity 11
Formula: C41H49N5O8
739.87
RM-L090111
((S)-5-(tert-butoxy)-2-((S)-2-((tert-butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-5-oxopentanoyl)glycine

Liraglutide Impurity 12
Formula: C29H35N3O8
553.61
RM-L090112
((S)-2-((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)propanamido)-5-(tert-butoxy)-5-oxopentanoyl)glycine

Liraglutide Impurity 13
Formula: C42H51N5O8
753.9
RM-L090113
(6S,9S,12S)-12-(3-(tert-butoxy)-3-oxopropyl)-2,2,9-trimethyl-4,7,10-trioxo-6-((1-trityl-1H-imidazol-4-yl)methyl)-3-oxa-5,8,11-triazatridecan-13-oic acid

Liraglutide Impurity 14
Formula: C44H54N6O9
810.95
RM-L090114
((S)-5-(tert-butoxy)-2-((R)-2-((S)-2-((tert-butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)propanamido)-5-oxopentanoyl)glycine

Liraglutide Impurity 15
Formula: C44H54N6O9
810.95
RM-L090115
((R)-5-(tert-butoxy)-2-((S)-2-((S)-2-((tert-butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)propanamido)-5-oxopentanoyl)glycine

Liraglutide Impurity 16
Formula: C64H101N5O16
1196.53
RM-L090116
(23S,50R)-50-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-23-(tert-butoxycarbonyl)-2,2-dimethyl-4,21,26,35,44-pentaoxo-3,30,33,39,42-pentaoxa-22,27,36,45-tetraazahenpentacontan-51-oic acid

Liraglutide Impurity 17
Formula: C64H101N5O16
1196.53
RM-L090117
(23R,50S)-50-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-23-(tert-butoxycarbonyl)-2,2-dimethyl-4,21,26,35,44-pentaoxo-3,30,33,39,42-pentaoxa-22,27,36,45-tetraazahenpentacontan-51-oic acid

Liraglutide Impurity 18
Formula: C58H90N4O13
1051.37
RM-L090118
(23R,41R)-41-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-23-(tert-butoxycarbonyl)-2,2-dimethyl-4,21,26,35-tetraoxo-3,30,33-trioxa-22,27,36-triazadotetracontan-42-oic acid

Liraglutide Impurity 19
Formula: C70H112N6O19
1341.69
RM-L090119
(23R,59R)-59-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-23-(tert-butoxycarbonyl)-2,2-dimethyl-4,21,26,35,44,53-hexaoxo-3,30,33,39,42,48,51-heptaoxa-22,27,36,45,54-pentaazahexacontan-60-oic acid

Liraglutide Impurity 2
Formula: C174H269N43O51
3779.32
RM-L090102
Liraglutide Impurity 2

Liraglutide Impurity 20
Formula: C71H107N5O16
1286.66
RM-L090120
5-benzyl 32,50-di-tert-butyl (5R,32R)-1-(9H-fluoren-9-yl)-3,11,20,29,34-pentaoxo-2,13,16,22,25-pentaoxa-4,10,19,28,33-pentaazapentacontane-5,32,50-tricarboxylate

Liraglutide Impurity 21
Formula: C55H86N4O13
1011.31
RM-L090121
(R)-45-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2,2-dimethyl-4,21,30,39-tetraoxo-3,25,28,34,37-pentaoxa-22,31,40-triazahexatetracontan-46-oic acid

Liraglutide Impurity 22
Formula: C42H61N5O13
843.97
RM-L090122
(5R,32R)-32-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-amino-2,2-dimethyl-4,8,17,26-tetraoxo-3,12,15,21,24-pentaoxa-9,18,27-triazatritriacontan-33-oic acid

Liraglutide Impurity 23
Formula: C24H49N3O2
411.68
RM-L090123
N-(3-(dimethylamino)propyl)-N-(ethylcarbamoyl)palmitamide

Liraglutide Impurity 24
Formula: C24H49N3O2
411.68
RM-L090124
N-((3-(dimethylamino)propyl)carbamoyl)-N-ethylpalmitamide

Liraglutide Impurity 25
Formula: C33H64N4O5
596.9
RM-L090125
tert-butyl N5-(3-(dimethylamino)propyl)-N5-(ethylcarbamoyl)-N2-palmitoyl-L-glutaminate

Liraglutide Impurity 26
Formula: C33H64N4O5
596.9
RM-L090126
tert-butyl N5-((3-(dimethylamino)propyl)carbamoyl)-N5-ethyl-N2-palmitoyl-L-glutaminate

Liraglutide Impurity 27
Formula: C34H62N2O8
626.88
RM-L090127
(S)-5-(tert-butoxy)-4-((R)-5-(tert-butoxy)-5-oxo-4-palmitamidopentanamido)-5-oxopentanoic acid

Liraglutide Impurity 28
Formula: C35H40N4O5
596.73
RM-L090128
methyl (S)-2-(2-((tert-butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoate

Liraglutide Impurity 29
Formula: C34H38N4O5
582.7
RM-L090129
(R)-2-(2-((tert-Butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic Acid

Liraglutide Impurity 3
Formula: C34H62N2O8
626.88
RM-L090103
Liraglutide Impurity 3

Liraglutide Impurity 30
Formula: C55H52N6O5
877.06
RM-L090130
Na-(Na-(tert-butoxycarbonyl)-Nt-trityl-L-histidyl)-Nt-trityl-L-histidine

Liraglutide Impurity 31
CAS:2490269-78-6
Formula: C27H32N2O7
496.56
RM-L090131
tert-butyl (S)-4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-((2-methoxy-2-oxoethyl)amino)-5-oxopentanoate

Liraglutide Impurity 32
Formula: C26H30N2O7
482.53
RM-L090132
(R)-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoyl)glycine

Liraglutide Impurity 33
Formula: C35H45N3O10
667.76
RM-L090133
((S)-2-((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanamido)-5-(tert-butoxy)-5-oxopentanoyl)glycine

Liraglutide Impurity 34
Formula: C29H35N3O8
553.61
RM-L090134
(S)-(2-(3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)propanamido)-5-(tert-butoxy)-5-oxopentanoyl)glycine

Liraglutide Impurity 35
CAS:3034424-49-9
Formula: C38H37N3O7
647.73
RM-L090135
N2,N6-bis(((9H-fluoren-9-yl)methoxy)carbonyl)-L-lysylglycine

Liraglutide Impurity 36
Formula: C26H29N3O5
463.53
RM-L090136
tert-butyl (S)-4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-((cyanomethyl)amino)-5-oxopentanoate

Liraglutide Impurity 37
Formula: C27H32N2O7
496.56
RM-L090137
(S)-N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoyl)-N-methylglycine

Liraglutide Impurity 38
CAS:872333-19-2
Formula: C33H38N2O6
558.68
RM-L090138
methyl N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-L-threonyl-L-phenylalaninate

Liraglutide Impurity 39
Formula: C32H36N2O6
544.65
RM-L090139
N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-D-allothreonyl-L-phenylalanine

Liraglutide Impurity 4
Formula: C172H265N43O51
3751.26
RM-L090104
Liraglutide Impurity 4

Liraglutide Impurity 40
Formula: C32H36N2O6
544.65
RM-L090140
N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-L-threonyl-D-phenylalanine

Liraglutide Impurity 41
Formula: C40H51N3O8
701.86
RM-L090141
N-(N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-L-threonyl)-O-(tert-butyl)-L-threonyl-L-phenylalanine

Liraglutide Impurity 42
Formula: C35H41N3O7
615.73
RM-L090142
N-(3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)propanoyl)-O-(tert-butyl)-L-threonyl-L-phenylalanine

Liraglutide Impurity 43
CAS:1082989-02-3
Formula: C29H30N2O5S
518.63
RM-L090143
(((9H-fluoren-9-yl)methoxy)carbonyl)-L-methionyl-L-phenylalanine

Liraglutide Impurity 44
Formula: C32H36N2O6
544.65
RM-L090144
N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-L-homoseryl-L-phenylalanine

Liraglutide Impurity 45
CAS:2301029-80-9
Formula: C30H32N2O5
500.6
RM-L090145
(((9H-fluoren-9-yl)methoxy)carbonyl)-L-isoleucyl-L-phenylalanine

Liraglutide Impurity 46
CAS:3029772-31-1
Formula: C45H43N3O7
737.85
RM-L090146
N2,N6-bis(((9H-fluoren-9-yl)methoxy)carbonyl)-L-lysyl-L-phenylalanine

Liraglutide Impurity 47
Formula: C37H35N3O8
649.7
RM-L090147
(2S,2'S)-2,2'-(((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)succinyl)bis(azanediyl))bis(3-phenylpropanoic acid)

Liraglutide Impurity 48
Formula: C28H36N2O6S
528.66
RM-L090148
N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-L-threonyl-L-methionine

Liraglutide Impurity 49
Formula: C32H36N2O7
560.65
RM-L090149
N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-L-threonyl-L-tyrosine

Liraglutide Impurity 5
Formula: C170H261N43O51
3723.21
RM-L090105
Liraglutide Impurity 5

Liraglutide Impurity 50
Formula: C29H38N2O6
510.63
RM-L090150
N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-L-threonyl-L-leucine

Liraglutide Impurity 51
Formula: C16H26N4O5
354.41
RM-L090151
methyl (S)-2-(2-((tert-butoxycarbonyl)amino)-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanoate

Liraglutide Impurity 52
Formula: C34H36N4O4
564.69
RM-L090152
2-cyanopropan-2-yl Na-(tert-butoxycarbonyl)-Nt-trityl-L-histidinate

Liraglutide Impurity 53
Formula: C34H37N5O3
563.7
RM-L090153
tert-butyl (S)-(1-((2-cyanopropan-2-yl)amino)-1-oxo-3-(1-trityl-1H-imidazol-4-yl)propan-2-yl)carbamate

Liraglutide Impurity 54
Formula: C34H39N5O4
581.72
RM-L090154
tert-butyl (S)-(1-((1-amino-2-methyl-1-oxopropan-2-yl)amino)-1-oxo-3-(1-trityl-1H-imidazol-4-yl)propan-2-yl)carbamate

Liraglutide Impurity 55
Formula: C25H27N3O8
497.5
RM-L090155
(2S,2'S)-2,2'-(((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)succinyl)bis(azanediyl))dipropionic acid

Liraglutide Impurity 56
CAS:169168-84-7
Formula: C22H22N2O7
426.43
RM-L090156
(((9H-fluoren-9-yl)methoxy)carbonyl)-L-alanyl-L-aspartic acid

Liraglutide Impurity 57
Formula: C26H29N3O8
511.53
RM-L090157
(2S,2'S)-2,2'-(((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)pentanedioyl)bis(azanediyl))dipropionic acid

Liraglutide Impurity 58
CAS:538334-42-8
Formula: C23H24N2O7
440.45
RM-L090158
(((9H-fluoren-9-yl)methoxy)carbonyl)-L-alanyl-L-glutamic acid

Liraglutide Impurity 59
CAS:294855-91-7
Formula: C25H42N2O7
482.62
RM-L090159
(S)-5-((2,5-dioxopyrrolidin-1-yl)oxy)-5-oxo-2-palmitamidopentanoic acid

Liraglutide Impurity 6
Formula: C193H302N44O55
4118.79
RM-L090106
Liraglutide Impurity 6

Liraglutide Impurity 60
Formula: C25H40N2O9
512.6
RM-L090160
(S)-16-((1-carboxy-4-((2,5-dioxopyrrolidin-1-yl)oxy)-4-oxobutyl)amino)-16-oxohexadecanoic acid

Liraglutide Impurity 61
CAS:1855872-05-7
Formula: C25H47NO5
441.65
RM-L090161
(R)-5-(tert-butoxy)-5-oxo-4-palmitamidopentanoic acid

Liraglutide Impurity 62(Fmoc-Thr(tBu)-Phe-OH)
CAS:1962160-86-6
Formula: C32H36N2O6
544.65
RM-L090162
N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-L-threonyl-L-phenylalanine

Liraglutide Impurity 7
Formula: C27H46N2O7
510.67
RM-L090107
1-(tert-butyl) 5-(2,5-dioxopyrrolidin-1-yl) tetradecanoyl-L-glutamate

Liraglutide Impurity 8
Formula: C43H53N5O8
767.92
RM-L090108
(6S,12R)-12-(3-(tert-butoxy)-3-oxopropyl)-2,2,9,9-tetramethyl-4,7,10-trioxo-6-((1-trityl-1H-imidazol-4-yl)methyl)-3-oxa-5,8,11-triazatridecan-13-oic acid

Liraglutide Impurity 9
Formula: C46H57N7O10
868
RM-L090109
((S)-5-(tert-butoxy)-2-((S)-2-((S)-2-((tert-butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)propanamido)-5-oxopentanoyl)glycylglycine

LISDEXAMFETAMINE DIMESYLATE
CAS:608137-33-3
Formula: C15H25N3O*2 CH4O3S
263.39*2 96.10
RM-A613001
(S)-2,6-diamino-N-((S)-1-phenylpropan-2-yl)hexanamide dimethanesulfonate

LISINOPRIL DIHYDRATE
CAS:83915-83-7
Formula: C21H31N3O5 2H2O
405.50 36.03
RM-L191400
(2S)-1-[(2S)-6-Amino-2-[[(1S)-1-carboxy-3-phenylpropyl]- amino]hexanoyl]pyrrolidine-2-carboxylic acid dihydrate; ((S)-1-carboxy-3-phenylpropyl)-L-lysyl-L-proline dihydrate

Lisinopril EP Impurity A; Enalapril Homophenylalanine Impurity
CAS:1012-05-1
Formula: C10H13NO2
179.22
RM-L191401
(2RS)-2-amino-4-phenylbutanoic acid

LISINOPRIL EP IMPURITY C
CAS:328385-86-0
Formula: C21H29N3O4
387.47
RM-L191403
(S)-2-((3S,8aS)-3-(4-aminobutyl)-1,4-dioxohexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-4-phenylbutanoic acid

LISINOPRIL EP IMPURITY D
CAS:219677-82-4
Formula: C21H29N3O4
387.47
RM-L191404
(S)-2-((3S,8aR)-3-(4-aminobutyl)-1,4-dioxohexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-4-phenylbutanoic acid

LISINOPRIL EP IMPURITY E
CAS:85955-59-5
Formula: C21H31N3O5
405.49
RM-L191405
(S)-1-((S)-6-amino-2-(((R)-1-carboxy-3-phenylpropyl)amino)hexanoyl)pyrrolidine-2-carboxylic acid

LISINOPRIL EP IMPURITY F
CAS:1132650-67-9
Formula: C21H37N3O5
411.54
RM-L191406
(S)-1-((S)-6-amino-2-(((S)-1-carboxy-3-cyclohexylpropyl)amino)hexanoyl)pyrrolidine-2-carboxylic acid

Lisinopril EP Impurity G (Dimer)
CAS:1356839-89-8
Formula: C42H60N6O9
792.96
RM-L191407
(S)-1-((S)-6-((S)-2-(((S)-6-amino-1-((S)-2-carboxypyrrolidin-1-yl)-1-oxohexan-2-yl)amino)-4-phenylbutanamido)-2-(((S)-1-carboxy-3-phenylpropyl)amino)hexanoyl)pyrrolidine-2-carboxylic acid

LISINOPRIL EP IMPURITY H
CAS:138247-43-5
Formula: C16H24N2O4
308.37
RM-L191408
(S)-6-amino-2-(((S)-1-carboxy-3-phenylpropyl)amino)hexanoic acid

LISINOPRIL EP IMPURITY I
CAS:927819-64-5
Formula: C31H41N3O7
567.67
RM-L191409
(2S)-1-[(2S)-2,6-Bis[[(1S)-1-Carboxy-3-phenylpropyl]-amino]hexanoyl]pyrrolidine- 2-carboxylic acid

LISINOPRIL IMPURITY 11
Formula: C37H53N5O8
695.85
RM-L191411
(2S)-1-((2S)-6-(6-amino-2-(((S)-1-carboxy-3-phenylpropyl)amino)hexanamido)-2-(((R)-1-carboxy-3-phenylpropyl)amino)hexanoyl)pyrrolidine-2-carboxylic acid

Lisinopril Impurity 12
Formula: C10H12F6N2O4
338.2
RM-L191412
(S)-2,6-bis(2,2,2-trifluoroacetamido)hexanoic acid

LISINOPRIL IMPURITY 13
Formula: C8H13F3N2O3
242.2
RM-L191413
(S)-6-amino-2-(2,2,2-trifluoroacetamido)hexanoic acid

LISINOPRIL IMPURITY 14
Formula: C20H25F3N2O6
446.42
RM-L191414
(S)-2-(((S)-1-ethoxy-1,4-dioxo-4-phenylbutan-2-yl)amino)-6-(2,2,2-trifluoroacetamido)hexanoic acid

LISINOPRIL IMPURITY 15
Formula: C20H25F3N2O6
446.42
RM-L191415
(S)-2-(((R)-1-ethoxy-1,4-dioxo-4-phenylbutan-2-yl)amino)-6-(2,2,2-trifluoroacetamido)hexanoic acid

LISINOPRIL IMPURITY 16
Formula: C20H27F3N2O5
432.43
RM-L191416
(S)-2-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-6-(2,2,2-trifluoroacetamido)hexanoic acid

LISINOPRIL IMPURITY 17
Formula: C20H33F3N2O5
438.48
RM-L191417
(S)-2-(((S)-4-cyclohexyl-1-ethoxy-1-oxobutan-2-yl)amino)-6-(2,2,2-trifluoroacetamido)hexanoic acid

LISINOPRIL IMPURITY 18
Formula: C30H38N2O6
522.63
RM-L191418
(S)-2-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-6-(((S)-1-(ethynyloxy)-1-oxo-4-phenylbutan-2-yl)amino)hexanoic acid

LISINOPRIL IMPURITY 19
Formula: C42H60N6O9
792.96
RM-L191419
(S)-1-((S)-6-((S)-1-((S)-6-amino-2-(((S)-1-carboxy-3-phenylpropyl)amino)hexanoyl)pyrrolidine-2-carboxamido)-2-(((S)-1-carboxy-3-phenylpropyl)amino)hexanoyl)pyrrolidine-2-carboxylic acid

LISINOPRIL IMPURITY 20
Formula: C42H58N6O8
774.95
RM-L191420
(2S,2'S)-1,1'-((3S,5S,12S,14S)-2,11-dioxo-3,12-diphenethyl-1,4,10,13-tetraazacyclooctadecane-5,14-dicarbonyl)bis(pyrrolidine-2-carboxylic acid)

Lisinopril Impurity 22
Formula: C37H53N5O8
695.86
RM-L191422
N2-((S)-1-carboxy-3-phenylpropyl)-N6-(((S)-1-carboxy-3-phenylpropyl)-L-lysyl)-L-lysyl-L-proline

LISINOPRIL IMPURITY 23
Formula: C25H34F3N3O6
529.56
RM-L191423
N2-((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)-N6-(2,2,2-trifluoroacetyl)-L-lysyl-L-proline

LISINOPRIL IMPURITY 24
CAS:112246-14-7
Formula: C25H34F3N3O6
529.56
RM-L191424
N2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)-N6-(2,2,2-trifluoroacetyl)-L-lysyl-L-proline

LISINOPRIL IMPURITY 25
CAS:219677-79-9
Formula: C25H32F3N3O5
511.54
RM-L191425
ethyl (S)-2-((3S,8aS)-1,4-dioxo-3-(4-(2,2,2-trifluoroacetamido)butyl)hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-4-phenylbutanoate

Lisinopril Impurity 26
CAS:199002-00-1
Formula: C25H40F3N3O6
535.61
RM-L191426
N2-(4-cyclohexyl-1-ethoxy-1-oxobutan-2-yl)-N6-(2,2,2-trifluoroacetyl)-L-lysyl-L-proline

Lisinopril Impurity 28;BOC-L-Proline
CAS:15761-39-4
Formula: C10H17NO4
215.25
RM-L191428
(tert-butoxycarbonyl)-L-proline

Lisinopril Impurity 32
CAS:1207346-27-7
Formula: C13H20BNO4
265.12
RM-L191432
(S)-(4-(2-amino-3-(tert-butoxy)-3-oxopropyl)phenyl)boronic acid

Lisinopril Impurity J
Formula: C31H41N3O7
567.68
RM-L191410
A name could not be generated for this structure.

Lisinopril Nitroso Impurity 27
CAS:519175-80-5
Formula: C21H30N4O6
434.49
RM-L191427
N2-((S)-1-carboxy-3-phenylpropyl)-N2-nitroso-L-lysyl-L-proline

LISINOPRIL-D5
CAS:1356905-39-9
Formula: C21H26N3O5D5
410.53
RM-L091905
Lisinopril-d5

LISOFYLLINE-D6
CAS:1185995-26-9
Formula: C13H14D6N4O3
286.36
RM-L462001
1-(5-hydroxyhexyl)-3,7-bis(methyl-d3)-3,7-dihydro-1H-purine-2,6-dione

LITHIUM ACETOACETATE
CAS:3483-11-2
Formula: C4H5O3 Li
101.08 6.94
RG-A261047
LITHIUM ACETOACETATE

LITHIUM AZIDE
CAS:19597-69-4
Formula: LiN3
48.96
RG-A260394
Lithium azide

LITHOCHOLIC ACID-2,2,4,4-D4
CAS:83701-16-0
Formula: C24H36D4O3
380.61
RM-L100002
Lithocholic acid-2,2,4,4-d4; (R)-4-((3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl-2,2,4,4-d4)pentanoic acid

LITHOSPERMIC ACID
CAS:28831-65-4
Formula: C27H22O12
538.46
RG-L012001
(2S,3S)-4-[(1E)-3-[(1R)-1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1- yl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-3-benzofurancarboxylic acid; (+)-Lithospermic acid; Lithospermic acid A; (2S,3S)-4-((E)-3-((R)-1-carboxy-2-

Lithospermic Acid Impurity 2
Formula: C27H22O12
538.46
RG-L012002
(E)-4-(3-(1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxoprop-1-en-1-yl)-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydrobenzofuran-3-carboxylic acid

LLY-507
CAS:1793053-37-8
Formula: C36H42N6O
574.76
RM-L250500
5-cyano-2'-[4-[2-(3-methyl-1H-indol-1-yl)ethyl]-1-piperazinyl]-N-[3-(1-pyrrol

LOBAPLATIN IMPURITY 1
Formula: C9H18N2O3Pt
397.33
RM-L150101
Lobaplatin Impurity 1

Lobaplatin Impurity 10
CAS:131392-27-3
Formula: C6H14Cl2N2Pt
380.18
RM-L150110
Lobaplatin Impurity 10

Lobaplatin Impurity 12
Formula: C6H14N2
114.19
RM-L150112
((1R,2R)-cyclobutane-1,2-diyl)dimethanamine

LOBAPLATIN IMPURITY 2
Formula: C9H18N2O3Pt
397.33
RM-L150102
Lobaplatin Impurity 2

Lobaplatin Impurity 3
Formula: C9H20N2O5Pt
431.35
RM-L150103
Lobaplatin Impurity 3

LOBAPLATIN IMPURITY 4
CAS:2497658-50-9
Formula: C9H18N2O3Pt
397.33
RM-L150104
Lobaplatin Impurity 4

LOBAPLATIN IMPURITY 5
CAS:2497658-49-6
Formula: C9H18N2O3Pt
397.33
RM-L150105
Lobaplatin Impurity 5

LOBAPLATIN IMPURITY 6
CAS:2496693-11-7
Formula: C9H18N2O3Pt
397.33
RM-L150106
Lobaplatin Impurity 6

LOBAPLATIN IMPURITY 7
CAS:2496693-10-6
Formula: C9H18N2O3Pt
397.33
RM-L150107
Lobaplatin Impurity 7

Lobaplatin Impurity 8
CAS:15286-88-1
Formula: C6H14N2
114.19
RM-L150108
((1R,2S)-cyclobutane-1,2-diyl)dimethanamine

LOBAPLATIN IMPURITY 9
CAS:1731-23-3
Formula: C6H14N2
114.19
RM-L150109
((1R,2R)-cyclobutane-1,2-diyl)dimethanamine

LOBELINE EP IMPURITY A
CAS:731823-86-2(HCl salt)
Formula: C22H27NO2
337.46
RM-L150201
2-((2S,6R)-6-((R)-2-hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethanone

LOBELINE EP IMPURITY B
CAS:579-21-5
Formula: C22H25NO2
335.44
RM-L150202
2,2'-((2R,6S)-1-methylpiperidine-2,6-diyl)bis(1-phenylethanone)

LOBELINE EP IMPURITY C
CAS:552-72-7
Formula: C22H29NO2
339.47
RM-L150203
(R)-2-((2R,6S)-6-((S)-2-hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethanol

LOBELINE HCL
CAS:134-63-4
Formula: C22H27NO2 HCl
337.46 36.46
RM-L150200
2-((2R,6S)-6-((S)-2-Hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethanone hydrochloride

Lobeline Impurity 10
Formula: C22H25NO2
335.45
RM-L150210
2,2'-((2S,6S)-1-methylpiperidine-2,6-diyl)bis(1-phenylethan-1-one)

Lobeline Impurity 11
CAS:888711-33-9
Formula: C22H25NO2
335.45
RM-L150211
2,2'-((2R,6R)-1-methylpiperidine-2,6-diyl)bis(1-phenylethan-1-one)--2,2'-((2S,6S)-1-methylpiperidine-2,6-diyl)bis(1-phenylethan-1-one) (1/1)

Lobeline Impurity 12
Formula: C22H29NO2
339.48
RM-L150212
2,2'-(1-methylpiperidine-2,6-diyl)bis(1-phenylethan-1-ol)

Lobeline Impurity 13
Formula: C22H27NO2
337.46
RM-L150213
2-((2S,6S)-6-((S)-2-hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethan-1-one

Lobeline Impurity 14
Formula: C22H27NO2
337.46
RM-L150214
2-((2S,6R)-6-((S)-2-hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethan-1-one

Lobeline Impurity 15
CAS:686709-76-2
Formula: C22H27NO2
337.46
RM-L150215
2-((2S,6R)-6-((S)-2-hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethan-1-one and 2-((2R,6S)-6-((R)-2-hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethan-1-one

Lobeline Impurity 16
Formula: C28H37NO4
451.61
RM-L150216
(S)-2-[(2R,6S)-1-Methyl-6-[(R)-2-phenyl-2-propionoxyethyl]-2-piperidyl]-1-phenylethyl propionate

Lobeline Impurity 17
Formula: C28H37NO4
451.61
RM-L150217
(1S,1'S)-((2R,6S)-1-methylpiperidine-2,6-diyl)bis(1-phenylethane-2,1-diyl) dipropionate

Lobeline Impurity 18
Formula: C25H31NO3
393.53
RM-L150218
(S)-2-((2R,6S)-1-methyl-6-(2-oxo-2-phenylethyl)piperidin-2-yl)-1-phenylethyl propionate

Lobeline Impurity 19
Formula: C25H31NO3
393.53
RM-L150219
(S)-2-((2S,6R)-1-methyl-6-(2-oxo-2-phenylethyl)piperidin-2-yl)-1-phenylethyl propionate

Lobeline Impurity 4
CAS:775271-34-6
Formula: C22H26ClNO
355.91
RM-L150204
2-((2R,6S)-6-((S)-2-chloro-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethan-1-one

Lobeline Impurity 5
CAS:140137-94-6
Formula: C21H20O2
304.39
RM-L150205
(2E,7E)-1,9-diphenylnona-2,7-diene-1,9-dione

Lobeline Impurity 6
CAS:1125824-42-1
Formula: C22H29NO2
339.48
RM-L150206
(1S,1'S)-2,2'-((2S,6R)-1-methylpiperidine-2,6-diyl)bis(1-phenylethan-1-ol)

Lobeline Impurity 7
Formula: C22H29NO2
339.48
RM-L150207
(1R,1'R)-2,2'-((2R,6R)-1-methylpiperidine-2,6-diyl)bis(1-phenylethan-1-ol)

Lobeline Impurity 8
Formula: C22H29NO2
339.48
RM-L150208
(1S,1'S)-2,2'-((2R,6R)-1-methylpiperidine-2,6-diyl)bis(1-phenylethan-1-ol)

Lobeline Impurity 9
Formula: C22H25NO2
335.45
RM-L150209
2,2'-((2R,6R)-1-methylpiperidine-2,6-diyl)bis(1-phenylethan-1-one)

LODOXAMIDE IMPURITY 2
Formula: C11H7ClN2O8
330.63
RM-L488002
2,2'-((5-carboxy-2-chloro-1,3-phenylene)bis(azanediyl))bis(2-oxoacetic acid)

LODOXAMIDE IMPURITY 3
Formula: C9H6ClN3O3
239.62
RM-L488003
2-((3-amino-2-chloro-5-cyanophenyl)amino)-2-oxoacetic acid

LODOXAMIDE IMPURITY 4
Formula: C11H8ClN3O7
329.65
RM-L488004
2,2'-((5-carbamoyl-2-chloro-1,3-phenylene)bis(azanediyl))bis(2-oxoacetic acid)

Lodoxamide Impurity 5
Formula: C7H8ClN3O
185.61
RM-L488005
3,5-diamino-4-chlorobenzamide