Founded in 2000, DIVERCHIM is the leading French Contract Research Organization in chemistry for life sciences companies. Our teams combine experience in drug discovery and process development, medicinal chemistry, parallel synthesis, biochemical tools and fine chemicals to deliver you with unique chemistry solutions to achieve your requirements. Diverchim specifies in complex multi-steps synthesis, low temperature chemistry, asymmetric, organometallic, cyclopropane, pyrrolidine, oxetane chemistry. Besides Diverchim can scale-up existing processes or develop a new process for existing products. Our Custom Synthesis capabilities range from mg scale to cGMP kilogram scale. Finally DIVERCHIM offers reference products for screening and building blocks for discovery (catalog).
Computer-Aided Drug Discovery
Virtual Screening / Docking
Pharmacophore search
Protein Homology Modeling
ADMET
Fragment based Drug Discovery
High throughput chemistry Support
Synthesis of reference compounds
Design and Synthesis of buildings blocks and scaffolds
Design, development and optimization of chemical routes
Custom and focused library synthesis
Design and synthesis of unique Building Blocks and Screening Collection
Fragment synthesis
Patented innovative technologies
Drug Discovery – Medicinal Chemistry
Hit generation
Hit selection to optimize
Hit to Lead transition
Lead Optimization
Chemical Development Support
Process Development
Route scouting and optimization
Scale-Up Synthesis
Multi kilogram Production
cGMP Production
Analytical Development
Analytical services
Structural Analysis
Quality Control
Preparative purification
Method development and validation
In house designed and produced innovative collection